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Results for grhl1

Z-value: 2.01

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Transcription factors associated with grhl1

Gene Symbol Gene ID Gene Info
ENSDARG00000061391 grainyhead-like transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
grhl1dr10_dc_chr17_-_32473712_324739130.861.8e-05Click!

Activity profile of grhl1 motif

Sorted Z-values of grhl1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of grhl1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_22386456 7.37 ENSDART00000146081
plac8 onzin related protein 5
chr6_+_17959219 6.62 ENSDART00000026448
envoplakin a
chr3_-_29846530 6.43 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr24_+_38783264 5.62 ENSDART00000154214
si:ch73-70c5.1
chr9_-_30453625 5.06 ENSDART00000060150
MID1 interacting protein 1a
chr16_-_9785057 4.65 ENSDART00000113724
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr6_-_43273456 4.63

chr16_+_13534390 4.28 ENSDART00000157396
ENSDARG00000022807
KN149859v1_+_16751 4.18 ENSDART00000167610
ENSDARG00000103399
chr22_+_21996941 4.05 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr21_-_22510751 3.89 ENSDART00000169870
myosin VB
chr9_-_40212864 3.88 ENSDART00000166918
IKAROS family zinc finger 2
chr16_+_7213011 3.71 ENSDART00000168830
ENSDART00000168274
ENSDART00000160383
ENSDART00000163281
BMP binding endothelial regulator
chr4_-_76620869 3.64

chr25_+_24520476 3.62

chr1_-_51862897 3.50 ENSDART00000136469
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr14_+_37206949 3.49

chr4_-_876235 3.25

chr1_-_23765358 3.24

chr21_-_13571753 3.19 ENSDART00000065819
chloride intracellular channel 3
chr3_-_18605846 3.09 ENSDART00000145277
zgc:113333
chr24_-_38782898 3.03 ENSDART00000155542
ENSDARG00000097123
chr16_+_7213161 3.03 ENSDART00000168830
ENSDART00000168274
ENSDART00000160383
ENSDART00000163281
BMP binding endothelial regulator
chr10_+_4924065 2.59 ENSDART00000108595
solute carrier family 46 member 2
chr21_-_3548719 2.55 ENSDART00000137844
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr4_-_9779763 2.55 ENSDART00000134280
SVOP-like
chr21_+_25588388 2.41 ENSDART00000134678
ENSDARG00000078256
chr7_+_22386328 2.31 ENSDART00000141048
plac8 onzin related protein 5
chr13_+_18401965 2.22 ENSDART00000136024
finTRIM family, member 14-like
chr4_+_4223606 2.05

chr2_+_35871754 2.02 ENSDART00000134918
DEAH (Asp-Glu-Ala-His) box helicase 9
chr23_+_17428740 1.84

chr1_-_51863187 1.81 ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr5_-_55745399 1.71

chr14_-_33604914 1.68 ENSDART00000168546
zinc finger, DHHC-type containing 24
chr5_-_6004819 1.54 ENSDART00000099570
tankyrase 1 binding protein 1
chr9_-_40212643 1.53 ENSDART00000166918
IKAROS family zinc finger 2
chr6_-_43273663 1.51

chr7_+_19583578 1.31 ENSDART00000149812
ovo-like zinc finger 1
chr10_+_4924008 1.31 ENSDART00000108595
solute carrier family 46 member 2
chr23_+_17428538 1.13

chr2_-_57502941 0.97

chr2_-_58272475 0.86 ENSDART00000166282
ENSDART00000159040
purine nucleoside phosphorylase 5b
chr14_+_4169846 0.85 ENSDART00000038301
glucosamine-6-phosphate deaminase 2
chr5_-_57016269 0.83 ENSDART00000074264
cytokine receptor family member B12
chr15_-_5913508 0.79 ENSDART00000155252
si:ch73-281n10.2
chr5_-_39440105 0.77 ENSDART00000157755
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr9_-_40213104 0.72 ENSDART00000166918
IKAROS family zinc finger 2
chr16_+_7213299 0.71 ENSDART00000162610
BMP binding endothelial regulator
chr15_+_29343644 0.69 ENSDART00000170537
ENSDART00000128973
RAP1 GTPase activating protein 2a
chr8_-_49227143 0.67

chr15_+_5914095 0.60 ENSDART00000114134
tryptophan rich basic protein
chr5_-_28970034 0.52 ENSDART00000043259
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2
chr16_+_35708856 0.47 ENSDART00000161393
MAP7 domain containing 1a
chr12_-_17013870 0.42

chr21_-_42813859 0.39

chr20_-_43448899 0.39 ENSDART00000152888
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4a
chr3_-_29846789 0.38 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr7_+_22421454 0.33

chr9_-_40213039 0.31 ENSDART00000166918
IKAROS family zinc finger 2
chr19_-_41887040 0.28 ENSDART00000062026
distal-less homeobox 5a
chr10_+_19568414 0.26 ENSDART00000162912
V-set and immunoglobulin domain containing 8a
chr23_-_22723966 0.19 ENSDART00000141127
carbonic anhydrase VI
chr14_+_4169371 0.19 ENSDART00000136665
glucosamine-6-phosphate deaminase 2
chr9_-_30453581 0.13 ENSDART00000060150
MID1 interacting protein 1a
chr23_-_22724076 0.10 ENSDART00000132733
carbonic anhydrase VI
chr19_-_20203902 0.08 ENSDART00000172668
ENSDARG00000101330
chr1_-_51863300 0.06 ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr4_-_9779987 0.05 ENSDART00000134280
SVOP-like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.8 4.6 GO:0045056 transcytosis(GO:0045056)
0.4 4.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 7.5 GO:0043049 neural crest formation(GO:0014029) otic placode formation(GO:0043049)
0.2 6.6 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.2 1.0 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 4.3 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.1 0.5 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 2.0 GO:0009615 response to virus(GO:0009615)
0.0 0.3 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 2.1 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0036269 swimming behavior(GO:0036269)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.6 GO:0005882 intermediate filament(GO:0005882)
0.1 5.4 GO:0016324 apical plasma membrane(GO:0016324)
0.1 3.9 GO:0016459 myosin complex(GO:0016459)
0.1 4.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 7.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.3 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0004046 aminoacylase activity(GO:0004046)
1.3 6.6 GO:0019215 intermediate filament binding(GO:0019215)
0.5 2.6 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.5 4.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 4.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 7.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 0.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 3.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 2.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 3.2 GO:0005254 chloride channel activity(GO:0005254)
0.1 0.5 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 2.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases