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Results for grhl1
Z-value: 2.01
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Transcription factors associated with grhl1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| grhl1 | dr10_dc_chr17_-_32473712_32473913 | 0.86 | 1.8e-05 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of grhl1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_22386456 Show fit | 7.37 |
ENSDART00000146081
|
plac8 onzin related protein 5 |
|
| chr6_+_17959219 Show fit | 6.62 |
ENSDART00000026448
|
envoplakin a |
|
| chr3_-_29846530 Show fit | 6.43 |
ENSDART00000077111
|
hydroxysteroid (17-beta) dehydrogenase 14 |
|
| chr24_+_38783264 Show fit | 5.62 |
ENSDART00000154214
|
si:ch73-70c5.1 |
|
| chr9_-_30453625 Show fit | 5.06 |
ENSDART00000060150
|
MID1 interacting protein 1a |
|
| chr16_-_9785057 Show fit | 4.65 |
ENSDART00000113724
|
mal, T-cell differentiation protein 2 (gene/pseudogene) |
|
| chr6_-_43273456 Show fit | 4.63 |
|
|
|
| chr16_+_13534390 Show fit | 4.28 |
ENSDART00000157396
|
ENSDARG00000022807 |
|
| KN149859v1_+_16751 Show fit | 4.18 |
ENSDART00000167610
|
ENSDARG00000103399 |
|
| chr22_+_21996941 Show fit | 4.05 |
ENSDART00000149586
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.5 | GO:0043049 | neural crest formation(GO:0014029) otic placode formation(GO:0043049) |
| 0.2 | 6.6 | GO:0045104 | intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104) |
| 0.8 | 4.6 | GO:0045056 | transcytosis(GO:0045056) |
| 0.1 | 4.3 | GO:0046890 | regulation of lipid biosynthetic process(GO:0046890) |
| 0.4 | 4.1 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 1.3 | 3.9 | GO:0003241 | growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 0.0 | 2.1 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 2.0 | GO:0009615 | response to virus(GO:0009615) |
| 0.2 | 1.0 | GO:0006041 | glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043) |
| 0.0 | 0.8 | GO:0007599 | blood coagulation(GO:0007596) hemostasis(GO:0007599) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.5 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 6.6 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 5.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 4.6 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 4.3 | GO:0005874 | microtubule(GO:0005874) |
| 0.1 | 4.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 3.9 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 3.2 | GO:0034707 | chloride channel complex(GO:0034707) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.5 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 1.3 | 6.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 1.3 | 5.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.5 | 4.6 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.5 | 4.1 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.2 | 3.9 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 3.2 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.5 | 2.6 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 2.0 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.2 | 1.0 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.9 | REACTOME AQUAPORIN MEDIATED TRANSPORT | Genes involved in Aquaporin-mediated transport |
| 0.0 | 2.0 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |