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DANIO-CODE

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Results for gsc

Z-value: 1.01

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Transcription factors associated with gsc

Gene Symbol Gene ID Gene Info
gsc
ENSDARG00000059073 goosecoid

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gscdr10_dc_chr17_-_19325678_193256880.234.0e-01Click!

Activity profile of gsc motif

Sorted Z-values of gsc motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gsc

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_26013873 4.87 ENSDART00000043932
atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr17_-_32473712 2.58 ENSDART00000148455
ENSDART00000149885
grhl1
grainyhead-like transcription factor 1
chr9_-_43178744 2.54

chr22_+_14068525 2.48 ENSDART00000080329
ENSDART00000115383
he1a
hatching enzyme 1a
chr6_-_43094573 2.46 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr23_-_27226280 2.26 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr11_-_29316162 2.20 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr25_+_182037 2.04 ENSDART00000156469
RPS17
ribosomal protein S17
chr19_-_32931355 2.00 ENSDART00000103410
zbtb8b
zinc finger and BTB domain containing 8B
chr14_-_36037883 1.90 ENSDART00000173006
gpm6aa
glycoprotein M6Aa
chr21_-_39239757 1.83

chr16_+_42925950 1.82 ENSDART00000159730
ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr5_+_44316830 1.74

chr9_+_38975508 1.73

chr23_+_36832325 1.73

chr5_+_59844830 1.72 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr5_+_59845054 1.70 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr15_-_15532980 1.58 ENSDART00000004220
ENSDART00000131259
rab34a
RAB34, member RAS oncogene family a
chr23_-_27226387 1.57 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr16_+_25180444 1.56 ENSDART00000157346
ENSDART00000155032
si:ch211-261d7.3
si:ch211-261d7.3
chr13_+_11305846 1.55

chr9_+_26292183 1.55

chr10_-_8029671 1.53 ENSDART00000141445
ewsr1a
EWS RNA-binding protein 1a
chr13_-_31491759 1.52 ENSDART00000057432
six1a
SIX homeobox 1a
chr10_+_32160464 1.51 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr5_-_28025315 1.51 ENSDART00000131729
tnc
tenascin C
chr17_+_45931793 1.49 ENSDART00000155372
kif26ab
kinesin family member 26Ab
chr3_+_45375639 1.48 ENSDART00000162799
crb3a
crumbs homolog 3a
chr5_-_28025439 1.41 ENSDART00000131729
tnc
tenascin C
chr1_-_44476084 1.37 ENSDART00000034549
zgc:111983
zgc:111983
chr16_+_19730756 1.32 ENSDART00000112894
sp8b
sp8 transcription factor b
chr16_+_19730820 1.27 ENSDART00000079201
sp8b
sp8 transcription factor b
chr2_-_30071872 1.25 ENSDART00000056747
shhb
sonic hedgehog b
chr11_+_18823629 1.25

chr10_-_37131530 1.24 ENSDART00000132023
myo18aa
myosin XVIIIAa
chr18_+_45121016 1.22 ENSDART00000172328
gyltl1b
glycosyltransferase-like 1b
chr13_-_50299821 1.19 ENSDART00000170527
vent
ventral expressed homeobox
chr23_-_5825236 1.17 ENSDART00000055087
phlda3
pleckstrin homology-like domain, family A, member 3
chr11_+_15478585 1.16 ENSDART00000163289
ENSDART00000066033
gdf11
growth differentiation factor 11
chr6_-_39278328 1.15 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr15_-_45229713 1.14

chr17_-_6191539 1.13 ENSDART00000081707
ENSDARG00000058775
ENSDARG00000058775
chr3_-_58739476 1.13 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr13_-_39821399 1.12 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr23_-_10202347 1.12 ENSDART00000142442
plxnb1a
plexin b1a
chr12_-_10001043 1.09 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr9_+_33167554 1.09 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr6_-_13215384 1.08 ENSDART00000112883
fmnl2b
formin-like 2b
chr14_+_34626233 1.00 ENSDART00000004550
rnf145a
ring finger protein 145a
chr19_-_42721857 0.98 ENSDART00000150919
ENSDART00000151034
si:ch211-191i18.2
si:ch211-191i18.2
chr3_+_23573114 0.96 ENSDART00000024256
hoxb6a
homeobox B6a
chr14_+_30390575 0.89 ENSDART00000087884
ccdc85b
coiled-coil domain containing 85B
chr2_-_30071815 0.87 ENSDART00000056747
shhb
sonic hedgehog b
chr11_+_30048913 0.86

chr13_-_33269297 0.85

chr23_+_41295092 0.85 ENSDART00000109567
nhsa
Nance-Horan syndrome a (congenital cataracts and dental anomalies)
chr5_+_58824344 0.85 ENSDART00000148727
gtf2ird1
GTF2I repeat domain containing 1
chr13_+_24417183 0.84 ENSDART00000177677
lgalslb
lectin, galactoside-binding-like b
chr7_-_38288929 0.84

chr11_-_40414239 0.83 ENSDART00000165163
si:ch211-222l21.1
si:ch211-222l21.1
chr13_-_50299643 0.83 ENSDART00000170527
vent
ventral expressed homeobox
chr7_-_49322226 0.82 ENSDART00000174161
brsk2b
BR serine/threonine kinase 2b
chr2_-_30071993 0.80 ENSDART00000056747
shhb
sonic hedgehog b
chr23_+_14058972 0.80 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr2_-_42222069 0.79 ENSDART00000142792
cspp1b
centrosome and spindle pole associated protein 1b
chr12_+_5495284 0.77 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr21_-_91068 0.77

chr4_-_14927871 0.76 ENSDART00000110199
prdm4
PR domain containing 4
chr5_-_56856570 0.76 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr23_-_4175790 0.76 ENSDART00000109807
ENSDARG00000076299
ENSDARG00000076299
chr23_-_10202175 0.75 ENSDART00000142442
plxnb1a
plexin b1a
chr23_+_6298911 0.75 ENSDART00000139795
syt2a
synaptotagmin IIa
chr22_-_26971466 0.73 ENSDART00000087202
ENSDARG00000061256
ENSDARG00000061256
chr24_+_37645966 0.73 ENSDART00000061203
rhot2
ras homolog family member T2
chr11_+_25266623 0.71 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b
chr8_+_14343513 0.69 ENSDART00000057642
acbd6
acyl-CoA binding domain containing 6
chr3_-_58739399 0.69 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr2_-_42011586 0.68 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr14_+_47326080 0.67 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr3_+_45375698 0.67 ENSDART00000162799
crb3a
crumbs homolog 3a
chr18_-_43890514 0.65 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr11_+_19894390 0.63 ENSDART00000103997
fezf2
FEZ family zinc finger 2
chr17_+_45931756 0.59 ENSDART00000155372
kif26ab
kinesin family member 26Ab
chr5_-_21520111 0.56

chr6_-_17699493 0.56 ENSDART00000154180
CR388029.1
ENSDARG00000097214
chr6_+_54931721 0.54

chr19_+_39100820 0.52

chr17_-_15141309 0.50 ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr20_-_25537241 0.50 ENSDART00000153266
itsn2a
intersectin 2a
chr14_+_7393010 0.49 ENSDART00000123139
brd8
bromodomain containing 8
chr11_+_30049412 0.47

chr6_-_35417797 0.47 ENSDART00000016586
rgs5a
regulator of G protein signaling 5a
chr5_+_69369417 0.47

chr17_+_45932080 0.46 ENSDART00000157326
kif26ab
kinesin family member 26Ab
chr21_+_15660541 0.45 ENSDART00000101956
ENSDART00000026903
ptpra
protein tyrosine phosphatase, receptor type, A
chr20_+_29685096 0.45 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr20_+_27088598 0.43 ENSDART00000012816
sel1l
sel-1 suppressor of lin-12-like (C. elegans)
chr5_-_13890202 0.43 ENSDART00000026120
ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr23_-_5825177 0.42 ENSDART00000055087
phlda3
pleckstrin homology-like domain, family A, member 3
chr4_+_5370319 0.42 ENSDART00000163797
ENSDARG00000014395
ENSDARG00000014395
chr19_-_42668754 0.41 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr3_-_16077831 0.40 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr10_+_13320935 0.39 ENSDART00000135082
tmem267
transmembrane protein 267
chr7_-_21639345 0.38 ENSDART00000111066
epoa
erythropoietin a
chr21_-_14950265 0.38 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr8_+_18584936 0.38 ENSDART00000089161
ENSDARG00000062021
ENSDARG00000062021
chr5_+_26217533 0.37

chr11_-_40414131 0.37 ENSDART00000165163
si:ch211-222l21.1
si:ch211-222l21.1
chr5_-_24302467 0.37

chr1_+_46400232 0.37 ENSDART00000036783
cryzl1
crystallin, zeta (quinone reductase)-like 1
chr1_-_45228793 0.33 ENSDART00000140890
pnpla6
patatin-like phospholipase domain containing 6
chr20_+_32646617 0.33

chr18_+_17765358 0.33 ENSDART00000137239
si:ch211-216l23.2
si:ch211-216l23.2
chr16_-_22903823 0.33

chr25_-_31970637 0.32 ENSDART00000006124
cops2
COP9 signalosome subunit 2
chr7_-_50244215 0.32 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr7_+_66660781 0.31 ENSDART00000082664
sbf2
SET binding factor 2
chr14_-_29459799 0.31 ENSDART00000005568
pdlim3b
PDZ and LIM domain 3b
chr5_+_42472789 0.30 ENSDART00000026020
wdr54
WD repeat domain 54
chr24_-_16760535 0.30 ENSDART00000066759
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr11_+_2437479 0.30 ENSDART00000130886
NABP2
nucleic acid binding protein 2
chr23_+_5631757 0.29 ENSDART00000059307
smpd2a
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr24_+_9740818 0.28 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr12_-_10667591 0.27 ENSDART00000164038
ENSDARG00000101171
ENSDARG00000101171
chr19_+_19224936 0.26 ENSDART00000171103
ddah2
dimethylarginine dimethylaminohydrolase 2
chr8_+_28493939 0.25 ENSDART00000053782
scrt2
scratch family zinc finger 2
chr13_+_11305968 0.24

chr15_+_30580253 0.24

chr8_+_28419432 0.24 ENSDART00000062706
tmem189
transmembrane protein 189
chr21_-_41994224 0.23 ENSDART00000092821
ENSDART00000165743
ENSDART00000075740
gabrg2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr9_-_28588288 0.21 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr3_-_5367142 0.20 ENSDART00000098927
txn2
thioredoxin 2
chr18_+_7680416 0.19 ENSDART00000132369
rabl2
RAB, member of RAS oncogene family-like 2
chr19_+_19225228 0.19 ENSDART00000166172
ddah2
dimethylarginine dimethylaminohydrolase 2
chr5_+_59845172 0.18 ENSDART00000130565
tmem132e
transmembrane protein 132E
chr2_-_22149297 0.17

chr5_+_25346893 0.17

chr5_+_63716392 0.16 ENSDART00000015940
edf1
endothelial differentiation-related factor 1
chr5_-_56856527 0.16 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr7_+_30698873 0.16 ENSDART00000155974
tjp1a
tight junction protein 1a
chr25_+_15983777 0.15 ENSDART00000165598
ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr25_-_22791839 0.15 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr19_-_25842461 0.14

chr19_+_19224736 0.13 ENSDART00000158228
ddah2
dimethylarginine dimethylaminohydrolase 2
chr23_-_17583239 0.12 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr3_-_30810423 0.12 ENSDART00000076830
coro1a
coronin, actin binding protein, 1A
chr23_-_28368224 0.12 ENSDART00000139537
znf385a
zinc finger protein 385A
chr6_-_39278397 0.11 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr8_+_36951655 0.10

chr7_+_52612436 0.10 ENSDART00000109973
tp53bp1
tumor protein p53 binding protein, 1
chr14_-_46564205 0.10 ENSDART00000111410
ganab
glucosidase, alpha; neutral AB
chr17_-_8498935 0.10 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr17_-_20959288 0.10 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr17_-_33462243 0.09 ENSDART00000131807
ccdc28a
coiled-coil domain containing 28A
chr20_-_18836593 0.09 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr6_-_13215294 0.08 ENSDART00000112883
fmnl2b
formin-like 2b
chr4_+_14928134 0.07 ENSDART00000019647
psmc2
proteasome 26S subunit, ATPase 2
chr24_+_3447129 0.06 ENSDART00000134598
wdr37
WD repeat domain 37
chr3_+_23573053 0.06 ENSDART00000024256
hoxb6a
homeobox B6a
chr7_+_41141295 0.05 ENSDART00000083967
chpf2
chondroitin polymerizing factor 2
chr24_-_16760393 0.05 ENSDART00000149706
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr20_+_29685331 0.04 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr17_+_45932212 0.02 ENSDART00000157326
kif26ab
kinesin family member 26Ab
chr5_+_18941935 0.02 ENSDART00000163064
ube3b
ubiquitin protein ligase E3B
chr6_+_30385605 0.01 ENSDART00000108943
shroom2a
shroom family member 2a
chr19_+_19225148 0.01 ENSDART00000166172
ddah2
dimethylarginine dimethylaminohydrolase 2
chr2_+_36845714 0.01 ENSDART00000140474
nrd1a
nardilysin a (N-arginine dibasic convertase)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0014819 regulation of skeletal muscle contraction(GO:0014819) positive regulation of muscle contraction(GO:0045933)
0.8 2.5 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) positive regulation of neuromuscular junction development(GO:1904398)
0.6 2.6 GO:0003334 keratinocyte development(GO:0003334)
0.6 1.9 GO:0035058 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855)
0.5 3.6 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.4 2.6 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.4 1.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.4 1.1 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.4 2.5 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.3 3.9 GO:0016540 protein autoprocessing(GO:0016540)
0.3 1.9 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.2 1.5 GO:0014857 skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 2.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 2.0 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 1.6 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 1.5 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.5 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.6 GO:1904407 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1 0.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.7 GO:0097345 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.1 1.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.1 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 1.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.4 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 1.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.9 GO:0001843 neural tube closure(GO:0001843)
0.0 1.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.4 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0051932 synaptic transmission, GABAergic(GO:0051932) regulation of postsynaptic membrane potential(GO:0060078)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 2.3 GO:0007018 microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.7 GO:0031672 A band(GO:0031672)
0.3 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 1.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0016234 inclusion body(GO:0016234)
0.1 1.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0000922 spindle pole(GO:0000922)
0.0 5.8 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.5 4.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.4 1.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 2.9 GO:0005113 patched binding(GO:0005113)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.8 GO:0051020 GTPase binding(GO:0051020)
0.1 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.4 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.2 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 2.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases