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Results for gsx2+pnx

Z-value: 0.83

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Transcription factors associated with gsx2+pnx

Gene Symbol Gene ID Gene Info
pnx
ENSDARG00000025899 posterior neuron-specific homeobox
gsx2
ENSDARG00000043322 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pnxdr10_dc_chr10_+_2772113_27721180.621.0e-02Click!
gsx2dr10_dc_chr20_-_22584941_225849530.591.5e-02Click!

Activity profile of gsx2+pnx motif

Sorted Z-values of gsx2+pnx motif

Network of associatons between targets according to the STRING database.

First level regulatory network of gsx2+pnx

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr22_-_35967525 2.84 ENSDART00000176971
CABZ01037120.1
ENSDARG00000106725
chr20_-_36984259 2.36 ENSDART00000076313
txlnba
taxilin beta a
chr13_+_35213326 2.00 ENSDART00000019323
jag1b
jagged 1b
chr9_-_30437160 1.90 ENSDART00000147241
BX936337.1
ENSDARG00000092870
chr12_-_4497094 1.84 ENSDART00000163651
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr14_+_6122948 1.81 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr17_-_35934175 1.79 ENSDART00000110040
ENSDART00000137525
sox11a
AL929378.1
SRY (sex determining region Y)-box 11a
ENSDARG00000092907
chr14_-_14337584 1.77 ENSDART00000167119
ENSDART00000168027
ENSDART00000167521
znf185
zinc finger protein 185 with LIM domain
chr3_-_23513177 1.71 ENSDART00000078425
eve1
even-skipped-like1
chr14_-_40022693 1.70 ENSDART00000149443
pcdh19
protocadherin 19
chr25_+_30699938 1.66 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr11_-_15162109 1.65 ENSDART00000124968
rpn2
ribophorin II
chr11_-_29910947 1.63 ENSDART00000156121
scml2
sex comb on midleg-like 2 (Drosophila)
chr7_+_56405531 1.62

chr25_+_31457309 1.58 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr19_+_17451381 1.58 ENSDART00000167602
spaca4l
sperm acrosome associated 4 like
chr1_-_57300743 1.58 ENSDART00000081122
COLGALT1 (1 of many)
collagen beta(1-O)galactosyltransferase 1
chr12_+_27032862 1.48

chr19_-_7576069 1.40 ENSDART00000148836
rfx5
regulatory factor X, 5
chr21_+_20512024 1.40 ENSDART00000126005
efna5a
ephrin-A5a
chr6_-_23193752 1.40 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr20_-_9107294 1.38 ENSDART00000140792
OMA1
OMA1 zinc metallopeptidase
chr15_-_4537178 1.36 ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr14_-_4038642 1.36 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr17_+_23278879 1.30 ENSDART00000153652
zgc:165461
zgc:165461
chr12_+_20230575 1.26 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr23_-_12310778 1.26 ENSDART00000131256
phactr3a
phosphatase and actin regulator 3a
chr23_+_19887319 1.26 ENSDART00000139192
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr17_+_134921 1.22 ENSDART00000166339
klhdc2
kelch domain containing 2
chr12_-_27032151 1.21 ENSDART00000153365
BX001014.2
ENSDARG00000096750
chr11_-_446028 1.16 ENSDART00000005923
zgc:77375
zgc:77375
chr2_-_24898678 1.15 ENSDART00000145145
cnn2
calponin 2
chr1_-_58580939 1.13 ENSDART00000158011
col5a3b
collagen, type V, alpha 3b
chr17_+_135165 1.13 ENSDART00000166339
klhdc2
kelch domain containing 2
chr11_-_6442836 1.11 ENSDART00000004483
zgc:162969
zgc:162969
chr25_-_13737344 1.10

chr6_-_7563110 1.08 ENSDART00000135945
rpsa
ribosomal protein SA
chr18_-_46260401 1.08 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
KN149726v1_+_1094 1.07

chr7_+_30516734 1.07 ENSDART00000174000
apba2b
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr9_+_36092350 1.05 ENSDART00000005086
atp1a1b
ATPase, Na+/K+ transporting, alpha 1b polypeptide
chr23_+_44137593 1.05 ENSDART00000148470
CU993818.1
ENSDARG00000095873
chr20_+_545574 1.05 ENSDART00000152453
dse
dermatan sulfate epimerase
chr3_-_23277066 1.04 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr25_+_34515221 1.04 ENSDART00000046218
flnca
filamin C, gamma a (actin binding protein 280)
chr21_-_3548719 1.03 ENSDART00000137844
atp8b1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr24_+_37752791 1.00 ENSDART00000158181
wdr24
WD repeat domain 24
chr4_+_73490746 0.97 ENSDART00000174082
nup50
nucleoporin 50
chr23_+_20183765 0.97 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr23_+_28656263 0.96 ENSDART00000020296
nadl1.2
neural adhesion molecule L1.2
chr8_-_15091823 0.96 ENSDART00000142358
bcar3
breast cancer anti-estrogen resistance 3
chr3_+_13114740 0.96 ENSDART00000162724
ENSDARG00000074231
ENSDARG00000074231
chr10_+_32160464 0.95 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr19_+_21783429 0.94 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr8_+_7740132 0.93 ENSDART00000171325
tfe3a
transcription factor binding to IGHM enhancer 3a
chr10_+_2952793 0.93

chr7_-_17129072 0.93

chr23_+_27052594 0.92 ENSDART00000109712
ENSDART00000018654
rnd1b
Rho family GTPase 1b
chr6_+_34528904 0.90 ENSDART00000161249
ENSDART00000166715
ENSDART00000161502
lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr3_-_60866373 0.89 ENSDART00000112043
cacng4b
calcium channel, voltage-dependent, gamma subunit 4b
chr12_-_28248133 0.89 ENSDART00000016283
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr13_-_25502297 0.88 ENSDART00000077627
ENSDART00000139237
ret
ret proto-oncogene receptor tyrosine kinase
chr4_+_292818 0.87 ENSDART00000103659
msgn1
mesogenin 1
chr15_-_14616083 0.86 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr15_-_35394535 0.86 ENSDART00000144153
mff
mitochondrial fission factor
chr1_+_55077656 0.86 ENSDART00000144983
tecrb
trans-2,3-enoyl-CoA reductase b
chr3_-_38642067 0.85 ENSDART00000155518
znf281a
zinc finger protein 281a
chr20_+_10502210 0.84 ENSDART00000155888
AL845550.1
ENSDARG00000097342
chr15_-_1858350 0.84 ENSDART00000082026
mmp28
matrix metallopeptidase 28
chr11_+_37639045 0.84 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr13_-_49695322 0.84

chr20_-_15734333 0.83 ENSDART00000176999
ENSDART00000179202
CABZ01015860.1
ENSDARG00000108793
chr7_-_23775835 0.82 ENSDART00000144616
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr1_-_50215233 0.79 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
KN149830v1_+_5168 0.79

chr19_+_48555386 0.79

chr16_+_51319421 0.78

chr22_+_16282153 0.78 ENSDART00000162685
ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr16_+_1302842 0.78

chr24_-_11768200 0.77 ENSDART00000033621
tm9sf1
transmembrane 9 superfamily member 1
chr3_-_15584548 0.75 ENSDART00000137325
mvp
major vault protein
chr6_+_6767424 0.75 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr2_+_33399405 0.75 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_+_39885307 0.73 ENSDART00000051055
ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr1_+_6833994 0.71 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr8_-_31098193 0.70 ENSDART00000098925
vgll4l
vestigial like 4 like
chr19_-_22956977 0.69 ENSDART00000019505
pleca
plectin a
chr23_-_31585883 0.67 ENSDART00000157511
eya4
EYA transcriptional coactivator and phosphatase 4
chr24_-_6048914 0.65 ENSDART00000146830
ENSDART00000021981
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr20_+_29307039 0.64 ENSDART00000152949
katnbl1
katanin p80 subunit B-like 1
chr4_+_75129077 0.64 ENSDART00000064312
ms4a17a.7
membrane-spanning 4-domains, subfamily A, member 17A.7
chr8_+_1760968 0.64 ENSDART00000021820
serpind1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr20_+_29307142 0.64 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr9_-_41608298 0.64

chr13_+_18414806 0.63 ENSDART00000110197
zgc:154058
zgc:154058
chr3_+_59491893 0.62 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr7_-_67906887 0.62 ENSDART00000171943
si:ch73-315f9.2
si:ch73-315f9.2
chr21_+_6829161 0.61 ENSDART00000037265
olfm1b
olfactomedin 1b
chr1_+_49894685 0.61 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr21_+_25496316 0.60

chr6_-_30671802 0.59 ENSDART00000065215
lurap1
leucine rich adaptor protein 1
chr1_-_518543 0.58 ENSDART00000138032
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr1_-_661529 0.58 ENSDART00000166786
ENSDART00000170483
appa
amyloid beta (A4) precursor protein a
chr6_-_39346614 0.58 ENSDART00000104074
zgc:158846
zgc:158846
chr8_-_19166630 0.58

chr25_+_4909062 0.57 ENSDART00000170049
parvb
parvin, beta
chr11_+_1495509 0.57 ENSDART00000139079
srsf6b
serine/arginine-rich splicing factor 6b
chr24_+_35500964 0.57 ENSDART00000058571
snai2
snail family zinc finger 2
chr11_-_41241693 0.57 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr14_+_5078937 0.56 ENSDART00000031508
lbx2
ladybird homeobox 2
chr7_-_19390325 0.55 ENSDART00000163686
si:ch211-212k18.4
si:ch211-212k18.4
chr8_+_52633069 0.54 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr11_+_43924640 0.54 ENSDART00000179206
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr6_+_24299180 0.53 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr1_-_57301027 0.53 ENSDART00000081122
COLGALT1 (1 of many)
collagen beta(1-O)galactosyltransferase 1
chr10_-_26782374 0.53 ENSDART00000162710
fgf13b
fibroblast growth factor 13b
chr14_-_3951077 0.53

chr6_-_23193873 0.52 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr25_-_2386615 0.52

chr19_+_32679320 0.52

chr5_-_30015572 0.52 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr23_+_36016450 0.51 ENSDART00000103035
hoxc6a
homeobox C6a
chr19_-_22957035 0.51 ENSDART00000019505
pleca
plectin a
chr24_+_33697332 0.51

chr3_+_13487523 0.51 ENSDART00000166000
si:ch211-194b1.1
si:ch211-194b1.1
chr4_+_22759177 0.51 ENSDART00000146272
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr19_-_3208938 0.51

chr5_-_27958815 0.51 ENSDART00000177313
si:ch73-195i19.3
si:ch73-195i19.3
chr3_-_60985683 0.51 ENSDART00000133091
pvalb5
parvalbumin 5
chr5_-_23649439 0.50

chr15_-_45446153 0.50 ENSDART00000100332
fgf12b
fibroblast growth factor 12b
chr23_-_10692678 0.49

chr19_+_32679258 0.49

chr4_-_935448 0.49 ENSDART00000171855
sim1b
single-minded family bHLH transcription factor 1b
chr3_-_31392769 0.48

chr11_+_18710724 0.48 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr15_+_34007335 0.47 ENSDART00000166141
tekt1
tektin 1
chr21_-_26453406 0.47 ENSDART00000009889
zgc:110540
zgc:110540
chr23_-_36198253 0.46

chr14_-_9407573 0.46 ENSDART00000166739
NRK
si:zfos-2326c3.2
chr20_-_46458839 0.46 ENSDART00000153087
bmf2
Bcl2 modifying factor 2
KN150127v1_+_2671 0.46

chr18_-_43890514 0.46 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr9_+_36316158 0.45 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr15_-_18110169 0.44

chr20_+_35479511 0.44 ENSDART00000135284
vsnl1a
visinin-like 1a
chr23_+_17220363 0.43 ENSDART00000143420
BX927275.2
ENSDARG00000095017
chr21_-_45550182 0.43 ENSDART00000163152
h2afy
H2A histone family, member Y
chr20_+_26981663 0.43 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr11_-_18068313 0.42

chr24_+_40292617 0.42

chr11_+_38013238 0.42 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr5_-_63031745 0.42

chr13_+_47175 0.42 ENSDART00000102505
foxg1d
forkhead box G1d
chr25_-_35530474 0.42

chr20_+_25326042 0.40 ENSDART00000130494
moxd1
monooxygenase, DBH-like 1
chr13_-_44492897 0.40

chr5_+_65754237 0.40 ENSDART00000170757
kntc1
kinetochore associated 1
chr5_-_68876416 0.40 ENSDART00000170885
eif2b1
eukaryotic translation initiation factor 2B, subunit 1 alpha
chr19_+_48555339 0.40

chr8_-_22252973 0.40 ENSDART00000131805
nphp4
nephronophthisis 4
KN149830v1_-_23361 0.38

chr23_-_46268313 0.38 ENSDART00000170417
ENSDART00000168352
CABZ01102528.1
ENSDARG00000098990
chr21_+_45802046 0.37 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr17_+_6295257 0.37 ENSDART00000064694
TATDN3
TatD DNase domain containing 3
chr20_-_23345739 0.37

chr16_+_13928376 0.37 ENSDART00000163251
flcn
folliculin
chr14_-_6831308 0.37 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr24_-_24859334 0.36 ENSDART00000080997
zdhhc20b
zinc finger, DHHC-type containing 20b
chr13_-_51409167 0.36 ENSDART00000174550
CABZ01090417.1
ENSDARG00000108080
chr4_+_11459212 0.36 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr12_-_41128584 0.36

chr17_-_37247505 0.35 ENSDART00000108514
asxl2
additional sex combs like transcriptional regulator 2
chr11_-_40464213 0.35 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr3_+_22392439 0.35

chr11_-_42263721 0.34 ENSDART00000130573
atp6ap1la
ATPase, H+ transporting, lysosomal accessory protein 1-like a
chr6_-_40886902 0.34 ENSDART00000017968
ENSDART00000154100
sirt4
sirtuin 4
chr19_+_21783111 0.34 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr9_-_30765708 0.34 ENSDART00000101085
morc3a
MORC family CW-type zinc finger 3a
chr6_-_57542101 0.33 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr21_-_45550252 0.33 ENSDART00000163152
h2afy
H2A histone family, member Y
chr16_-_43029548 0.33 ENSDART00000057305
thbs3a
thrombospondin 3a
chr8_+_25015374 0.33 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr4_+_15072119 0.33

chr1_+_127240 0.32 ENSDART00000122230
f7i
coagulation factor VIIi
chr13_-_40600924 0.32 ENSDART00000099847
ENSDART00000057046
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr17_+_135261 0.32 ENSDART00000166339
klhdc2
kelch domain containing 2
chr2_-_27065203 0.32 ENSDART00000148110
si:dkey-181m9.8
si:dkey-181m9.8
chr20_+_35479428 0.32 ENSDART00000159483
ENSDART00000031091
BX511024.1
vsnl1a
ENSDARG00000104812
visinin-like 1a
chr3_+_27667194 0.32 ENSDART00000075100
carhsp1
calcium regulated heat stable protein 1
chr23_+_20779487 0.32 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr2_+_50873893 0.32

chr3_-_30494171 0.32 ENSDART00000151698
syt3
synaptotagmin III
chr11_+_26238579 0.31 ENSDART00000165097
unm_sa1614
un-named sa1614
chr20_-_15029379 0.31 ENSDART00000152641
dnm3a
dynamin 3a
chr10_-_41478085 0.31 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr6_+_40924749 0.31 ENSDART00000133599
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr6_+_9441851 0.31 ENSDART00000064995
sumo1
small ubiquitin-like modifier 1
chr6_-_39201300 0.30 ENSDART00000077938
c1galt1b
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr20_+_17899547 0.30

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.3 0.9 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.3 0.9 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.2 1.7 GO:0033700 phospholipid efflux(GO:0033700)
0.2 0.6 GO:0097702 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.2 2.0 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 1.2 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.2 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.7 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.2 0.9 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 1.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 0.4 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.1 1.2 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 1.3 GO:0015671 oxygen transport(GO:0015671)
0.1 0.7 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 2.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.0 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.0 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.1 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.3 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.3 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.1 0.8 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 1.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.0 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0036372 opsin transport(GO:0036372)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.7 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.8 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.3 GO:0010883 regulation of lipid storage(GO:0010883)
0.0 1.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0007286 spermatid development(GO:0007286)
0.0 1.0 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.9 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.6 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.3 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.2 0.6 GO:0097224 sperm connecting piece(GO:0097224)
0.2 1.6 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 1.3 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.6 GO:0005861 troponin complex(GO:0005861)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0031430 M band(GO:0031430)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.3 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.6 GO:0042645 nucleoid(GO:0009295) ribonuclease P complex(GO:0030677) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.1 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.5 GO:0031514 motile cilium(GO:0031514)
0.0 0.4 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 1.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.6 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.6 GO:0008665 tRNA 2'-phosphotransferase activity(GO:0000215) 2'-phosphotransferase activity(GO:0008665)
0.1 1.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.4 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.7 GO:0043295 glutathione binding(GO:0043295)
0.1 0.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.8 GO:0005112 Notch binding(GO:0005112)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.0 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.6 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.1 GO:0043236 laminin binding(GO:0043236)
0.1 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 2.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.3 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.9 GO:0019199 transmembrane receptor protein tyrosine kinase activity(GO:0004714) transmembrane receptor protein kinase activity(GO:0019199)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.1 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 5.5 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.6 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.0 REACTOME TRANSLATION Genes involved in Translation
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis