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Results for hbp1

Z-value: 0.49

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Transcription factors associated with hbp1

Gene Symbol Gene ID Gene Info
hbp1
ENSDARG00000028517 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hbp1dr10_dc_chr25_-_3345176_33452050.647.4e-03Click!

Activity profile of hbp1 motif

Sorted Z-values of hbp1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hbp1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_31606213 1.10 ENSDART00000126873
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr7_-_8128948 1.03 ENSDART00000057101
aep1
aerolysin-like protein
chr19_-_43037791 0.99 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr24_+_4341242 0.90 ENSDART00000133360
ccny
cyclin Y
chr6_+_23787804 0.79 ENSDART00000163188
znf648
zinc finger protein 648
chr14_+_5852295 0.68 ENSDART00000128638
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr2_+_9263844 0.65 ENSDART00000028906
pigk
phosphatidylinositol glycan anchor biosynthesis, class K
chr9_+_30767182 0.65 ENSDART00000139811
commd6
COMM domain containing 6
chr25_+_558191 0.63 ENSDART00000126863
ENSDART00000166012
nell2a
neural EGFL like 2a
chr20_-_44598129 0.59 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr20_+_26981663 0.55 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr7_-_25426346 0.54 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr15_+_16950266 0.54 ENSDART00000049196
gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr6_-_24003717 0.53 ENSDART00000164915
scinla
scinderin like a
chr19_+_43843780 0.51 ENSDART00000151571
ahdc1
AT hook, DNA binding motif, containing 1
chr17_-_26893412 0.51 ENSDART00000045842
rcan3
regulator of calcineurin 3
chr13_-_12513113 0.48

chr14_-_2278018 0.48 ENSDART00000125674
pcdh2ab9
protocadherin 2 alpha b 9
chr6_+_60190849 0.46

chr12_-_48948928 0.46 ENSDART00000163734
rgrb
retinal G protein coupled receptor b
chr3_+_43010408 0.45 ENSDART00000169061
CU138533.1
ENSDARG00000099842
chr17_+_37306052 0.45 ENSDART00000134000
tmem62
transmembrane protein 62
chr7_-_23751107 0.42 ENSDART00000149133
cideb
cell death-inducing DFFA-like effector b
chr8_+_48624273 0.41 ENSDART00000121432
nppa
natriuretic peptide A
chr24_-_6868340 0.40 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr6_+_54931721 0.39

chr14_-_34172522 0.38 ENSDART00000140368
si:ch211-232m8.3
si:ch211-232m8.3
chr19_+_10912601 0.37 ENSDART00000053325
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr13_-_49546922 0.36

chr4_+_9027862 0.36 ENSDART00000102893
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr9_-_34068225 0.36 ENSDART00000088441
ENSDART00000150035
si:ch73-147f11.1
si:ch73-147f11.1
chr11_+_24640015 0.34 ENSDART00000006038
shisa4
shisa family member 4
chr7_+_73466424 0.33 ENSDART00000123429
si:dkey-46i9.6
si:dkey-46i9.6
chr6_-_40724581 0.33 ENSDART00000035101
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr25_-_34677352 0.33 ENSDART00000115210
ano9a
anoctamin 9a
chr23_+_23255489 0.31 ENSDART00000137353
klhl17
kelch-like family member 17
chr16_+_5625552 0.31

chr1_+_39545535 0.30 ENSDART00000045697
zgc:56493
zgc:56493
chr18_+_17622557 0.30 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr18_+_11747188 0.29 ENSDART00000051105
tmtc2b
transmembrane and tetratricopeptide repeat containing 2b
chr11_-_25181234 0.29 ENSDART00000013714
gata1a
GATA binding protein 1a
chr24_+_25872051 0.28 ENSDART00000137851
tfr1b
transferrin receptor 1b
chr18_-_19114558 0.28 ENSDART00000177621
dennd4a
DENN/MADD domain containing 4A
chr15_+_32439470 0.26 ENSDART00000153657
trim3a
tripartite motif containing 3a
chr16_-_54638972 0.25

chr1_-_32647357 0.25 ENSDART00000136383
cd99
CD99 molecule
chr19_-_32900108 0.25 ENSDART00000050130
gmpr
guanosine monophosphate reductase
chr17_-_45036982 0.24 ENSDART00000155043
tmed8
transmembrane p24 trafficking protein 8
chr23_-_41002187 0.24 ENSDART00000061037
ENSDARG00000041644
ENSDARG00000041644
chr14_-_17000025 0.24 ENSDART00000168853
jakmip1
janus kinase and microtubule interacting protein 1
chr7_+_27420387 0.23 ENSDART00000079091
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr12_-_17079132 0.22 ENSDART00000020541
lipf
lipase, gastric
chr3_-_23277066 0.22 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr1_-_12584179 0.22

chr10_-_20567013 0.22 ENSDART00000159060
ddhd2
DDHD domain containing 2
chr22_+_29694605 0.22

chr11_-_3592968 0.21 ENSDART00000085855
dnajc16l
DnaJ (Hsp40) homolog, subfamily C, member 16 like
chr2_-_19532470 0.21 ENSDART00000166881
BX323588.1
ENSDARG00000102520
chr18_-_39797167 0.21 ENSDART00000169916
dmxl2
Dmx-like 2
chr14_-_34172619 0.20 ENSDART00000147380
ENSDARG00000092889
ENSDARG00000092889
chr13_-_22713071 0.19 ENSDART00000142738
pbld
phenazine biosynthesis like protein domain containing
chr8_+_50498398 0.18

chr14_+_5852428 0.17 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr16_+_22114192 0.17 ENSDART00000167919
znf687a
zinc finger protein 687a
chr7_+_28630661 0.16 ENSDART00000113998
dok4
docking protein 4
chr10_+_35479226 0.16 ENSDART00000147303
hhla2a.1
HERV-H LTR-associating 2a, tandem duplicate 1
chr19_+_46647893 0.15 ENSDART00000162785
ENSDART00000171251
ENSDART00000164938
mapk15
mitogen-activated protein kinase 15
chr1_-_9364331 0.13 ENSDART00000054835
ENSDART00000125358
rnf175
ring finger protein 175
chr1_-_54366578 0.12 ENSDART00000170001
vps54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr6_-_42143595 0.11 ENSDART00000085472
grm2a
glutamate receptor, metabotropic 2a
chr13_+_13875110 0.11 ENSDART00000131875
atrn
attractin
chr19_+_25009921 0.10

chr14_+_34626233 0.10 ENSDART00000004550
rnf145a
ring finger protein 145a
chr13_-_41821890 0.09 ENSDART00000132808
nanp
N-acetylneuraminic acid phosphatase
chr1_-_55765067 0.09 ENSDART00000037576
slc25a10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr7_-_51364562 0.09 ENSDART00000174131
rps4x
ribosomal protein S4, X-linked
chr8_+_27536121 0.09 ENSDART00000016696
rhocb
ras homolog family member Cb
chr14_+_7071129 0.08 ENSDART00000142158
hars
histidyl-tRNA synthetase
chr19_+_31944725 0.08 ENSDART00000136289
tmem64
transmembrane protein 64
chr11_-_18281078 0.07

chr24_+_9371496 0.07

chr11_+_44805115 0.06 ENSDART00000167828
tmc6b
transmembrane channel-like 6b
chr9_-_23177842 0.06

chr25_+_35787139 0.06 ENSDART00000073402
si:ch211-113a14.16
si:ch211-113a14.16
chr21_+_21575563 0.06 ENSDART00000008099
b9d2
B9 protein domain 2
chr3_+_47412661 0.05 ENSDART00000155648
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr5_-_18457877 0.04 ENSDART00000142531
ankle2
ankyrin repeat and LEM domain containing 2
chr20_+_47639141 0.04 ENSDART00000043938
tram2
translocation associated membrane protein 2
chr12_-_6871799 0.03 ENSDART00000171511
ENSDART00000171846
ENSDART00000166531
ENSDART00000152322
pcdh15b
protocadherin-related 15b
chr10_-_14582293 0.03 ENSDART00000039161
hdhd2
haloacid dehalogenase-like hydrolase domain containing 2
chr16_+_7325399 0.03 ENSDART00000081477
sri
sorcin
chr17_+_53277665 0.02 ENSDART00000129236
wu:fe17e08
wu:fe17e08
chr17_+_45824480 0.02

chr16_+_5625788 0.02

chr14_+_7596207 0.02 ENSDART00000113299
zgc:110843
zgc:110843
chr22_+_13862110 0.02 ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr1_+_19376651 0.01 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr1_+_28860348 0.00 ENSDART00000154342
ENSDART00000088290
raph1b
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.2 0.5 GO:0002280 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.1 0.9 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.5 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.1 0.3 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691) phospholipid homeostasis(GO:0055091)
0.1 0.3 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.1 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.2 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 1.1 GO:0014823 response to activity(GO:0014823)
0.1 0.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.4 GO:0043649 coenzyme catabolic process(GO:0009109) dicarboxylic acid catabolic process(GO:0043649)
0.1 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.5 GO:0007602 phototransduction(GO:0007602)
0.0 1.0 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)
0.0 0.5 GO:0019722 calcium-mediated signaling(GO:0019722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0046930 pore complex(GO:0046930)
0.1 0.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 1.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.4 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.0 0.4 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0051427 hormone receptor binding(GO:0051427)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D