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Results for hdx

Z-value: 0.78

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Transcription factors associated with hdx

Gene Symbol Gene ID Gene Info
hdx
ENSDARG00000079382 highly divergent homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hdxdr10_dc_chr14_-_5918482_5918516-0.702.5e-03Click!

Activity profile of hdx motif

Sorted Z-values of hdx motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hdx

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_12916555 2.12 ENSDART00000140691
si:ch211-167j6.3
si:ch211-167j6.3
chr6_+_23476669 1.80

chr21_-_2296253 1.73 ENSDART00000162867
zgc:66483
zgc:66483
chr5_+_52199662 1.71

chr6_-_2000017 1.66 ENSDART00000158535
vstm2l
V-set and transmembrane domain containing 2 like
chr2_+_34984631 1.59 ENSDART00000141796
astn1
astrotactin 1
chr21_-_7334721 1.57 ENSDART00000136671
f2rl1.1
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
chr5_-_17502869 1.45 ENSDART00000129878
zdhhc8b
zinc finger, DHHC-type containing 8b
chr23_+_32174669 1.42 ENSDART00000000992
ENSDARG00000000887
ENSDARG00000000887
chr10_-_25608902 1.32 ENSDART00000147876
grik1a
glutamate receptor, ionotropic, kainate 1a
chr12_+_30673985 1.31 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr10_-_36849540 1.30

chr16_-_26947117 1.29 ENSDART00000111156
pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr5_-_63773138 1.27 ENSDART00000172321
brd3b
bromodomain containing 3b
chr3_-_39316317 1.25

chr2_+_37312637 1.24 ENSDART00000056519
gpr160
G protein-coupled receptor 160
chr10_-_36849596 1.19

chr2_-_54224744 1.14

chr23_+_44730111 1.13 ENSDART00000177271
trappc1
trafficking protein particle complex 1
chr23_+_19728953 1.11 ENSDART00000104441
abhd6b
abhydrolase domain containing 6b
chr7_-_13416823 1.09 ENSDART00000056893
pdcd7
programmed cell death 7
chr20_-_34894930 1.08

chr10_-_36849734 1.07

chr11_-_24300849 1.07 ENSDART00000171004
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr14_+_31265616 1.06

chr8_-_53165501 1.02 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr7_+_40866623 1.01 ENSDART00000052274
puf60b
poly-U binding splicing factor b
chr15_-_26954009 1.01 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr5_+_62611606 0.97 ENSDART00000177108
si:ch73-376l24.2
si:ch73-376l24.2
chr23_+_10870124 0.97 ENSDART00000035693
ppp4r2a
protein phosphatase 4, regulatory subunit 2a
chr12_-_26529300 0.96 ENSDART00000162163
ENSDART00000087067
hexdc
hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing
chr2_+_46210971 0.96

chr16_-_43491205 0.95

chr7_+_15479700 0.95

chr22_+_2049719 0.92

chr22_+_11943005 0.91 ENSDART00000105788
mgat5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr21_+_7570595 0.91 ENSDART00000161921
zgc:113019
zgc:113019
chr16_-_7703633 0.88 ENSDART00000148581
CT574585.1
ENSDARG00000095852
chr23_+_37476457 0.88 ENSDART00000178064
AL954146.3
ENSDARG00000108629
chr11_+_8142982 0.87 ENSDART00000166379
samd13
sterile alpha motif domain containing 13
chr23_-_42918086 0.86 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr20_-_34894607 0.85

chr7_+_35163845 0.85 ENSDART00000173733
BX294178.2
ENSDARG00000104955
chr1_+_58608231 0.84 ENSDART00000161872
ENSDART00000160658
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr2_+_46210909 0.83

chr7_+_38690837 0.82 ENSDART00000173565
dgkza
diacylglycerol kinase, zeta a
chr15_-_6949405 0.78 ENSDART00000019330
ech1
enoyl CoA hydratase 1, peroxisomal
chr16_+_42567707 0.78 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr14_+_30058172 0.77 ENSDART00000053925
mtmr7a
myotubularin related protein 7a
chr19_+_5052459 0.75 ENSDART00000003634
stard3
StAR-related lipid transfer (START) domain containing 3
chr10_-_36849472 0.75

chr23_-_42918055 0.73 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr8_+_36527653 0.72 ENSDART00000136418
ENSDART00000061378
sf3a1
splicing factor 3a, subunit 1
chr5_-_13945310 0.71 ENSDART00000157675
kat6a
K(lysine) acetyltransferase 6A
chr2_-_40067309 0.71

chr19_+_20404995 0.69 ENSDART00000142841
osbpl3a
oxysterol binding protein-like 3a
chr7_+_48025010 0.69 ENSDART00000052123
slc25a44b
solute carrier family 25, member 44 b
chr22_-_4787016 0.68 ENSDART00000140313
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr1_-_22577855 0.67 ENSDART00000175685
rfc1
replication factor C (activator 1) 1
chr11_-_24300785 0.67 ENSDART00000171004
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr15_-_26953872 0.65 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr22_-_11024649 0.65 ENSDART00000105823
ENSDART00000159995
insrb
insulin receptor b
chr6_-_2000167 0.64 ENSDART00000160475
vstm2l
V-set and transmembrane domain containing 2 like
chr22_+_35156074 0.63 ENSDART00000130581
rnf13
ring finger protein 13
chr17_+_6378694 0.63 ENSDART00000062952
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr3_-_59690168 0.62 ENSDART00000035878
cdr2l
cerebellar degeneration-related protein 2-like
chr1_+_58608185 0.62 ENSDART00000161872
ENSDART00000160658
parn
poly(A)-specific ribonuclease (deadenylation nuclease)
chr22_+_35229352 0.62 ENSDART00000061315
ENSDART00000146430
tsc22d2
TSC22 domain family 2
chr1_-_20919505 0.61

chr13_+_13814142 0.61 ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr4_+_377994 0.61 ENSDART00000148933
rpl18a
ribosomal protein L18a
chr5_+_1109967 0.61 ENSDART00000046781
ENSDART00000163101
rnf185
ring finger protein 185
chr2_-_37299150 0.61 ENSDART00000137598
nadkb
NAD kinase b
chr19_+_20405107 0.60 ENSDART00000151066
osbpl3a
oxysterol binding protein-like 3a
chr2_-_41035670 0.59 ENSDART00000123886
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr6_-_41023836 0.58 ENSDART00000103776
hdhd3
haloacid dehalogenase-like hydrolase domain containing 3
chr3_-_33789615 0.58

chr22_-_23252993 0.58 ENSDART00000105613
si:dkey-121a9.3
si:dkey-121a9.3
chr10_+_33758581 0.57 ENSDART00000141650
b3glctb
beta 3-glucosyltransferase b
chr18_+_5199305 0.57 ENSDART00000020233
zdhhc7
zinc finger, DHHC-type containing 7
chr5_+_56539999 0.56 ENSDART00000167660
pja2
praja ring finger 2
chr18_+_9755131 0.55

chr6_-_22910576 0.54 ENSDART00000164114
grb2a
growth factor receptor-bound protein 2a
chr10_+_39972154 0.54 ENSDART00000003435
smfn
small fragment nuclease
chr22_-_9866462 0.54 ENSDART00000138343
znf990
zinc finger protein 990
chr13_+_33578737 0.54 ENSDART00000161465
CABZ01087953.1
ENSDARG00000104106
chr25_+_11212787 0.54 ENSDART00000159583
FQ312013.1
ENSDARG00000099473
chr16_+_32128415 0.53 ENSDART00000137029
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr16_+_19223683 0.52 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr14_-_11714513 0.52 ENSDART00000106654
znf711
zinc finger protein 711
chr24_+_39750793 0.51 ENSDART00000133284
luc7l
LUC7-like (S. cerevisiae)
chr10_-_36848930 0.51

KN150384v1_+_17709 0.51

chr3_-_25361866 0.50 ENSDART00000147322
grb2b
growth factor receptor-bound protein 2b
chr5_-_56539892 0.50

chr23_-_15280634 0.50 ENSDART00000056570
phf20b
PHD finger protein 20, b
chr22_+_1568354 0.49 ENSDART00000175704
si:ch211-255f4.11
si:ch211-255f4.11
chr10_+_1653868 0.49 ENSDART00000018532
triap1
TP53 regulated inhibitor of apoptosis 1
chr23_-_42918166 0.48 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr6_-_31361901 0.48 ENSDART00000153734
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr11_+_33154781 0.48

chr16_-_7703754 0.47 ENSDART00000148581
CT574585.1
ENSDARG00000095852
chr2_-_41035732 0.47 ENSDART00000123886
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr3_-_25361708 0.47 ENSDART00000147322
grb2b
growth factor receptor-bound protein 2b
chr8_+_25988813 0.47 ENSDART00000058100
xpc
xeroderma pigmentosum, complementation group C
chr24_+_9740978 0.46 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr6_-_6138267 0.46 ENSDART00000092172
mtif2
mitochondrial translational initiation factor 2
chr11_+_42310157 0.45 ENSDART00000085868
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr6_-_41023783 0.44 ENSDART00000103776
hdhd3
haloacid dehalogenase-like hydrolase domain containing 3
chr13_+_46429054 0.44 ENSDART00000160401
tmem63ba
transmembrane protein 63Ba
chr5_+_13146987 0.43 ENSDART00000139199
h2afva
H2A histone family, member Va
chr1_+_43822319 0.42 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr3_-_52837780 0.42 ENSDART00000062081
lpar2a
lysophosphatidic acid receptor 2a
chr9_-_12678315 0.42

chr22_-_4786947 0.42 ENSDART00000140313
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr14_-_30150071 0.41 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr22_+_35229139 0.39 ENSDART00000061315
ENSDART00000146430
tsc22d2
TSC22 domain family 2
chr23_-_465425 0.39 ENSDART00000140749
si:ch73-181d5.4
si:ch73-181d5.4
chr13_+_9510368 0.39 ENSDART00000140504
prdx3
peroxiredoxin 3
chr7_-_13416289 0.39

chr7_+_17701669 0.37 ENSDART00000113120
taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr12_+_26785950 0.37 ENSDART00000087329
znf438
zinc finger protein 438
chr12_+_3834709 0.37 ENSDART00000066546
nif3l1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr15_-_26954063 0.37 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr8_-_17130906 0.36

chr25_-_23485520 0.36 ENSDART00000149107
nap1l4a
nucleosome assembly protein 1-like 4a
chr17_-_970957 0.36 ENSDART00000177536
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17
chr6_+_8078889 0.35 ENSDART00000134245
gcdha
glutaryl-CoA dehydrogenase a
chr5_-_6182820 0.35 ENSDART00000168698
ostf1
osteoclast stimulating factor 1
chr20_+_50249994 0.34 ENSDART00000047212
cpsf2
cleavage and polyadenylation specific factor 2
chr6_+_40566498 0.34 ENSDART00000154766
si:ch73-15b2.5
si:ch73-15b2.5
chr24_+_39769129 0.33 ENSDART00000066500
ENSDART00000145075
stub1
STIP1 homology and U-Box containing protein 1
chr5_+_25080638 0.32 ENSDART00000134242
zfand5a
zinc finger, AN1-type domain 5a
chr5_-_63773215 0.32 ENSDART00000168030
brd3b
bromodomain containing 3b
chr9_+_12917201 0.32 ENSDART00000102386
si:ch211-167j6.4
si:ch211-167j6.4
chr5_+_61278798 0.31 ENSDART00000168808
si:dkeyp-117b8.4
si:dkeyp-117b8.4
chr5_+_36066523 0.31 ENSDART00000097686
zgc:153990
zgc:153990
chr13_+_18377514 0.30

chr10_-_36849108 0.30

chr9_-_2756749 0.30

chr6_+_54568649 0.30 ENSDART00000157142
tead3b
TEA domain family member 3 b
chr2_+_31823314 0.30 ENSDART00000086608
ranbp9
RAN binding protein 9
chr16_+_42567668 0.29 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr10_-_44441197 0.29 ENSDART00000160231
sbno1
strawberry notch homolog 1 (Drosophila)
chr17_+_6378932 0.28 ENSDART00000062952
slc5a6b
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
chr7_+_15479520 0.28

chr24_-_36248243 0.28 ENSDART00000065336
tmem14cb
transmembrane protein 14Cb
chr3_+_33788977 0.27 ENSDART00000055248
alkbh7
alkB homolog 7
chr12_+_30119447 0.27 ENSDART00000102081
afap1l2
actin filament associated protein 1-like 2
chr9_-_32532616 0.26 ENSDART00000078499
rftn2
raftlin family member 2
chr6_+_54568388 0.26 ENSDART00000093199
tead3b
TEA domain family member 3 b
chr23_-_39879096 0.25 ENSDART00000159519
ENSDARG00000102199
ENSDARG00000102199
chr16_+_19223553 0.25 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr24_+_33478309 0.25 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr9_+_26029780 0.24 ENSDART00000127135
gtdc1
glycosyltransferase-like domain containing 1
chr7_+_34216448 0.24 ENSDART00000109872
cln6a
CLN6, transmembrane ER protein a
chr9_+_56868126 0.24 ENSDART00000160107
CU639413.1
ENSDARG00000100275
chr6_-_40165125 0.23 ENSDART00000153956
ip6k2b
inositol hexakisphosphate kinase 2b
chr22_+_18904372 0.23 ENSDART00000131131
bsg
basigin
chr25_+_3619832 0.23

chr11_+_42184049 0.22 ENSDART00000056048
si:ch1073-165f9.2
si:ch1073-165f9.2
chr5_-_17502894 0.21 ENSDART00000129878
zdhhc8b
zinc finger, DHHC-type containing 8b
chr22_+_35156212 0.21 ENSDART00000131952
ENSDART00000003303
rnf13
ring finger protein 13
chr6_+_6674857 0.20 ENSDART00000151343
ENSDARG00000077040
ENSDARG00000077040
chr18_-_22105000 0.20 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr16_+_23580507 0.19 ENSDART00000021092
snx27b
sorting nexin family member 27b
chr5_-_7591027 0.19 ENSDART00000158447
nipbla
nipped-B homolog a (Drosophila)
chr7_+_19779221 0.19 ENSDART00000052904
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr24_-_24999348 0.18 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr16_+_27449058 0.18 ENSDART00000132329
stx17
syntaxin 17
chr16_+_51290761 0.18 ENSDART00000058290
dhdds
dehydrodolichyl diphosphate synthase
chr19_-_24971920 0.18 ENSDART00000132660
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr25_+_15901561 0.17 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr8_+_36527535 0.16 ENSDART00000136418
ENSDART00000061378
sf3a1
splicing factor 3a, subunit 1
chr9_-_32489944 0.16 ENSDART00000078596
hspd1
heat shock 60 protein 1
chr10_+_8142976 0.16 ENSDART00000123447
pstpip2
proline-serine-threonine phosphatase interacting protein 2
chr3_-_25361754 0.16 ENSDART00000147322
grb2b
growth factor receptor-bound protein 2b
chr1_-_28146457 0.16 ENSDART00000110270
ENSDART00000170797
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr24_+_39768911 0.16 ENSDART00000066500
ENSDART00000145075
stub1
STIP1 homology and U-Box containing protein 1
chr25_+_10714737 0.15 ENSDART00000167730
anpepb
alanyl (membrane) aminopeptidase b
chr5_+_26820868 0.13 ENSDART00000098590
cyb561a3a
cytochrome b561 family, member A3a
chr5_-_23179648 0.13

chr25_+_35784138 0.12 ENSDART00000152761
CR354435.7
ENSDARG00000094744
chr1_-_22577723 0.12 ENSDART00000143948
rfc1
replication factor C (activator 1) 1
chr4_-_72627654 0.12 ENSDART00000112820
zgc:165515
zgc:165515
chr18_+_5199209 0.11 ENSDART00000020233
zdhhc7
zinc finger, DHHC-type containing 7
chr10_+_9512758 0.11 ENSDART00000141869
rbm18
RNA binding motif protein 18
chr19_+_19164500 0.11 ENSDART00000165728
vps52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr11_+_42310184 0.10 ENSDART00000085868
appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr7_-_48123296 0.10 ENSDART00000174381
sin3ab
SIN3 transcription regulator family member Ab
chr11_+_30049041 0.09

chr14_+_26421549 0.09 ENSDART00000172927
eef1g
eukaryotic translation elongation factor 1 gamma
chr16_+_39292206 0.08 ENSDART00000127319
ENSDART00000102510
zgc:77056
zgc:77056
chr25_+_17765920 0.08 ENSDART00000151853
btbd10a
BTB (POZ) domain containing 10a
chr20_+_21578759 0.08

chr8_-_16702377 0.07 ENSDART00000100706
ndufaf2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr5_+_71409912 0.07 ENSDART00000165835
ddx54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr3_+_26092485 0.07 ENSDART00000128284
nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr24_-_17255674 0.06 ENSDART00000134947
ENSDART00000122757
cul1b
cullin 1b
chr4_+_26047568 0.06 ENSDART00000126474
si:ch211-265o23.1
si:ch211-265o23.1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.4 0.7 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.3 0.8 GO:0070655 mechanosensory epithelium regeneration(GO:0070655) mechanoreceptor differentiation involved in mechanosensory epithelium regeneration(GO:0070656) neuromast regeneration(GO:0070657) neuromast hair cell differentiation involved in neuromast regeneration(GO:0070658)
0.3 1.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 1.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.9 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.2 1.3 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 2.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.4 GO:0032675 interleukin-6 production(GO:0032635) regulation of interleukin-6 production(GO:0032675)
0.1 2.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 2.0 GO:0007099 centriole replication(GO:0007099)
0.1 2.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0008211 glucocorticoid metabolic process(GO:0008211) regulation of steroid metabolic process(GO:0019218)
0.1 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.7 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.7 GO:0030301 cholesterol transport(GO:0030301)
0.0 1.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.3 GO:0070265 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.6 GO:0035329 hippo signaling(GO:0035329)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.4 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.4 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:0071005 U4 snRNP(GO:0005687) U2-type precatalytic spliceosome(GO:0071005)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.2 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.2 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.7 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 1.0 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.5 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 0.9 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.0 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 0.7 GO:0019705 protein-cysteine S-myristoyltransferase activity(GO:0019705)
0.2 2.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 2.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094) dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.1 2.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.6 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 2.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER