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Results for hey1+heyl_hey2

Z-value: 0.55

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Transcription factors associated with hey1+heyl_hey2

Gene Symbol Gene ID Gene Info
ENSDARG00000055798 hes related family bHLH transcription factor with YRPW motif like
ENSDARG00000070538 hes-related family bHLH transcription factor with YRPW motif 1
ENSDARG00000013441 hes-related family bHLH transcription factor with YRPW motif 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hey1dr10_dc_chr19_-_32214978_322149900.312.4e-01Click!
hey2dr10_dc_chr20_-_39693535_396935920.234.0e-01Click!

Activity profile of hey1+heyl_hey2 motif

Sorted Z-values of hey1+heyl_hey2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hey1+heyl_hey2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_14531021 0.83 ENSDART00000170954
si:dkey-102m7.3
chr19_-_24971633 0.68 ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr25_-_34608926 0.62 ENSDART00000130395
histone 1, H4, like
chr25_-_35817806 0.55 ENSDART00000129969
ENSDARG00000086604
chr7_+_24770873 0.52 ENSDART00000165314
ENSDARG00000103682
chr20_-_25726868 0.49 ENSDART00000126716
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr2_-_24661477 0.49 ENSDART00000078975
ENSDART00000155677
tRNA selenocysteine 1 associated protein 1b
chr7_+_58718614 0.48 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr8_+_17148864 0.48 ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr12_-_7572970 0.48 ENSDART00000158095
solute carrier family 16, member 9b
chr10_+_4962403 0.46 ENSDART00000134679
ENSDARG00000093688
chr6_-_47842137 0.46 ENSDART00000141986
leucine-rich repeats and immunoglobulin-like domains 2
chr19_+_7233537 0.44 ENSDART00000080348
bromodomain containing 2a
chr10_-_8029671 0.44 ENSDART00000141445
EWS RNA-binding protein 1a
chr22_+_16471319 0.44 ENSDART00000014330
immediate early response 5
chr10_-_44441481 0.44 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr20_+_32503118 0.44 ENSDART00000018640
sorting nexin 3
chr2_+_25363717 0.44 ENSDART00000142601
stromal antigen 1a
chr20_-_23184142 0.43 ENSDART00000176282
ENSDARG00000108718
chr11_-_16840339 0.43 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr11_+_3940085 0.42 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr1_-_674449 0.42 ENSDART00000160564
cysteine/tyrosine-rich 1
chr19_+_42899678 0.41 ENSDART00000076915
si:dkey-166k12.1
chr15_+_1187249 0.41 ENSDART00000152638
ENSDART00000152466
myeloid leukemia factor 1
chr16_-_45103102 0.41 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_-_791149 0.38 ENSDART00000151782
ENSDART00000037515
misato 1, mitochondrial distribution and morphology regulator
chr10_-_22065636 0.38

chr16_+_43468861 0.38

chr24_+_32754013 0.37 ENSDART00000156638
si:ch211-282b22.1
chr4_-_21931540 0.37 ENSDART00000174400
ribosomal protein S16
chr11_+_30416953 0.36

chr13_+_46514162 0.36 ENSDART00000159260
ENSDARG00000098286
chr7_-_73530653 0.35 ENSDART00000166633
ENSDART00000009888
ENSDART00000171254
calsequestrin 1b
chr19_+_43524098 0.35 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1, like 2
chr13_+_31271568 0.35 ENSDART00000019202
tudor domain containing 9
chr9_-_41044622 0.34 ENSDART00000143384
si:dkey-95p16.1
chr11_+_44922098 0.34 ENSDART00000172999
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr13_-_18506153 0.33 ENSDART00000057869
methionine adenosyltransferase I, alpha
chr12_+_24221087 0.33 ENSDART00000088178
neurexin 1a
chr24_-_12794564 0.33 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr8_+_23192085 0.33 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr20_+_45989418 0.32 ENSDART00000131169
bone morphogenetic protein 2b
chr22_-_120677 0.31

chr19_+_7234029 0.31 ENSDART00000080348
bromodomain containing 2a
chr21_-_20728623 0.30 ENSDART00000135940
ENSDART00000002231
growth hormone receptor b
chr6_-_28231995 0.29 ENSDART00000131126
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr3_+_1455113 0.29 ENSDART00000065922
WBP2 N-terminal like
chr21_-_20674965 0.28 ENSDART00000065649
ENSDARG00000044676
chr17_+_27383737 0.28 ENSDART00000156756
ENSDARG00000097369
chr7_-_6205157 0.28 ENSDART00000172884
histone 1, H4, like
chr24_-_26339981 0.28 ENSDART00000135496
eukaryotic translation initiation factor 5A
chr5_+_4033390 0.28 ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr20_+_54464026 0.27 ENSDART00000158810
ENSDART00000161631
ENSDART00000172631
ENSDART00000168924
FK506 binding protein 3
chr24_-_12794672 0.27 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr6_-_60152594 0.27 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr8_+_166461 0.26

chr5_-_41039135 0.26 ENSDART00000083644
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr9_+_24255064 0.26 ENSDART00000101577
ENSDART00000159324
ENSDART00000023196
ENSDART00000079689
ENSDART00000172743
ENSDART00000171577
leucine rich repeat (in FLII) interacting protein 1a
chr24_-_33869817 0.26 ENSDART00000079283
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr6_-_60152693 0.25 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr3_-_10455344 0.25 ENSDART00000111833
phosphatidylcholine transfer protein
chr3_+_54327353 0.25 ENSDART00000127487
eukaryotic translation initiation factor 3, subunit G
chr19_+_34145030 0.25 ENSDART00000151521
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_19114558 0.25 ENSDART00000177621
DENN/MADD domain containing 4A
chr19_+_43523303 0.24 ENSDART00000167847
eukaryotic translation elongation factor 1 alpha 1, like 2
chr7_+_44373815 0.24 ENSDART00000170721
si:dkey-56m19.5
chr4_+_11054808 0.24 ENSDART00000140362
coiled-coil domain containing 59
chr20_-_48677794 0.24 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr9_-_785511 0.23 ENSDART00000012506
engrailed homeobox 1a
KN150670v1_-_72156 0.23

chr3_+_1455242 0.23 ENSDART00000065922
WBP2 N-terminal like
chr8_+_23716843 0.23 ENSDART00000136547
ribosomal protein L10a
chr3_+_32394653 0.23 ENSDART00000150897
si:ch73-367p23.2
chr2_-_9691594 0.23 ENSDART00000146715
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr5_+_23625065 0.23 ENSDART00000029719
si:ch211-114c12.2
chr7_-_29811734 0.23 ENSDART00000075600
tetraspanin 3b
chr23_-_32043229 0.23 ENSDART00000134550
ORMDL sphingolipid biosynthesis regulator 2
chr1_+_16683931 0.22 ENSDART00000103262
ENSDART00000145068
ENSDART00000169619
ENSDART00000010526
FAT atypical cadherin 1a
chr18_+_9524331 0.22 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
KN150487v1_+_15409 0.22 ENSDART00000166996
ENSDARG00000100224
chr14_-_31676235 0.22 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr8_+_20406797 0.22 ENSDART00000016422
MAP kinase interacting serine/threonine kinase 2b
chr2_-_42525768 0.22 ENSDART00000026339
GTP binding protein 4
chr6_+_42821679 0.22 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr18_-_17031173 0.22 ENSDART00000129146
TBC1 domain family, member 15
chr2_+_5297505 0.22 ENSDART00000108990
peroxisomal biogenesis factor 5-like b
chr9_+_54692834 0.22

chr12_-_22438379 0.22 ENSDART00000177715
ENSDARG00000108493
chr24_-_8592157 0.21 ENSDART00000082351
transcription factor AP-2 alpha
chr11_+_7139675 0.21 ENSDART00000155864
ENSDARG00000097452
chr8_-_17148743 0.21 ENSDART00000025803
polymerase (DNA directed), alpha 2
chr23_+_35964754 0.21 ENSDART00000103147
homeobox C12a
chr5_+_22173976 0.21 ENSDART00000142112
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr18_-_21229799 0.21 ENSDART00000060160
calbindin 2a
chr24_+_12845250 0.21 ENSDART00000126842
hypothetical protein FLJ11011-like (H. sapiens)
chr21_-_776741 0.20

chr16_+_7213011 0.20 ENSDART00000168830
ENSDART00000168274
ENSDART00000160383
ENSDART00000163281
BMP binding endothelial regulator
chr19_-_9192541 0.20

chr1_-_22144014 0.20 ENSDART00000043556
LIM domain binding 2b
chr25_+_36872560 0.20 ENSDART00000163178
solute carrier family 10, member 3
chr7_-_28376722 0.20 ENSDART00000150148
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr4_-_16835283 0.20 ENSDART00000165289
glycogen synthase 2
chr12_+_30471781 0.20 ENSDART00000126984
nebulin-related anchoring protein
chr16_-_15496868 0.19 ENSDART00000053754
hyaluronan synthase 2
chr10_+_29351676 0.19 ENSDART00000088973
synaptotagmin-like 2a
chr5_+_2384929 0.19

chr2_+_50126676 0.19 ENSDART00000145483
ribosomal protein L37
chr12_+_19262722 0.19 ENSDART00000078266
ribosomal L1 domain containing 1
chr3_+_28871566 0.19

chr1_-_54087595 0.19 ENSDART00000150362
si:ch211-197k17.3
chr18_+_14725148 0.18 ENSDART00000146128
URI1, prefoldin-like chaperone
chr7_-_40713381 0.18 ENSDART00000031700
engrailed homeobox 2a
chr18_+_9524247 0.18 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_-_13922285 0.18 ENSDART00000080334
YY1 associated factor 2
chr18_-_26876598 0.18

chr13_-_40190349 0.18 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr7_+_67244332 0.18 ENSDART00000170322
ribosomal protein L13
chr15_-_2689005 0.18 ENSDART00000063325
claudin f
chr15_+_16961487 0.18 ENSDART00000154679
yippee-like 2b
chr5_-_9162684 0.17

chr24_+_23599223 0.17

chr10_+_5422223 0.17 ENSDART00000063093
AU RNA binding protein/enoyl-CoA hydratase
chr1_-_17073539 0.17

chr11_+_39768718 0.17 ENSDART00000130278
si:dkey-264d12.1
chr23_+_7614867 0.17 ENSDART00000011554
transmembrane 9 superfamily protein member 4
chr6_-_12883682 0.17 ENSDART00000165375
zgc:194469
chr10_-_11053655 0.17 ENSDART00000132995
adenylate kinase 3
chr25_-_20994084 0.17 ENSDART00000154765
proline rich 5a (renal)
KN150680v1_+_10854 0.17

chr16_+_53632229 0.17 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr20_+_1887099 0.17

chr24_-_12794057 0.17 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr12_-_9479063 0.17 ENSDART00000169727
si:ch211-207i20.3
chr18_+_20001243 0.17 ENSDART00000090310
protein inhibitor of activated STAT, 1b
chr15_+_19902697 0.17 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr20_-_128304 0.17 ENSDART00000149581
yippee-like 5
chr18_+_44802349 0.17 ENSDART00000139526
family with sequence similarity 118, member B
chr2_-_58737903 0.17

chr6_+_60190849 0.16

chr1_+_30142256 0.16 ENSDART00000022841
methionyl aminopeptidase type 1D (mitochondrial)
chr22_+_17581859 0.16 ENSDART00000035670
polymerase (RNA) II (DNA directed) polypeptide E, b
chr8_-_387126 0.16

chr21_+_713673 0.16

chr16_-_24697750 0.16 ENSDART00000163305
FXYD domain containing ion transport regulator 6 like
chr18_-_5260386 0.16 ENSDART00000027115
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr1_-_50215233 0.16 ENSDART00000137648
si:dkeyp-123h10.2
chr22_+_18228143 0.16 ENSDART00000141535
ENSDARG00000095557
chr18_+_9524184 0.16 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr19_-_24971920 0.16 ENSDART00000132660
polymerase (RNA) III (DNA directed) polypeptide G like a
chr18_+_5260471 0.16 ENSDART00000150992
WD repeat domain 59
chr20_-_5324678 0.16 ENSDART00000114316
serine palmitoyltransferase, long chain base subunit 2b
chr17_+_19479310 0.16 ENSDART00000077804
solute carrier family 22, member 15
chr6_+_60152913 0.15

chr25_-_35817715 0.15 ENSDART00000129969
ENSDARG00000086604
chr12_-_34621359 0.15

chr8_-_31597252 0.15 ENSDART00000018886
growth hormone receptor a
chr19_+_2754903 0.15 ENSDART00000160533
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr9_+_56881036 0.15

chr10_+_22942760 0.15 ENSDART00000134790
mediator complex subunit 11
chr6_-_57479360 0.15 ENSDART00000128065
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr20_+_27341026 0.15 ENSDART00000123950
ENSDARG00000077377
chr19_+_34582100 0.15 ENSDART00000135592
POC1 centriolar protein homolog B (Chlamydomonas), like
chr25_+_222244 0.15 ENSDART00000155344
ENSDARG00000073905
chr11_-_42826276 0.15

chr4_+_830826 0.15

chr24_+_42133471 0.15 ENSDART00000170514
topoisomerase (DNA) I, mitochondrial
chr12_+_27194414 0.15 ENSDART00000087204
dual specificity phosphatase 3a
chr16_+_24045707 0.15 ENSDART00000058965
apolipoprotein Eb
chr8_-_16577737 0.15 ENSDART00000139038
ENSDARG00000092337
chr20_-_22478716 0.15 ENSDART00000110967
ENSDART00000011135
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr7_+_5846555 0.15 ENSDART00000083397
histone 1, H4, like
chr1_+_157674 0.14 ENSDART00000152205
ENSDART00000160843
cullin 4A
chr5_+_68410884 0.14 ENSDART00000153691
ENSDARG00000097815
chr16_+_22950567 0.14 ENSDART00000143957
flavin adenine dinucleotide synthetase 1
chr7_-_71092394 0.14 ENSDART00000081245
DEAH (Asp-Glu-Ala-His) box helicase 15
chr1_+_30840656 0.14 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr3_-_34208423 0.14 ENSDART00000151634
trinucleotide repeat containing 6C1
chr10_+_5267746 0.14 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr24_-_8592102 0.14 ENSDART00000082351
transcription factor AP-2 alpha
chr13_+_24531753 0.14 ENSDART00000014176
muscle segment homeobox 3
chr17_+_53068731 0.14 ENSDART00000156774
diphthamine biosynthesis 6
chr13_-_25068717 0.14 ENSDART00000057605
adenosine kinase a
chr20_-_158899 0.14 ENSDART00000131635
solute carrier family 16 (aromatic amino acid transporter), member 10
chr3_+_53518347 0.14 ENSDART00000170461
collagen, type V, alpha 3a
chr22_-_520129 0.14 ENSDART00000001201
bystin-like
chr25_+_18866796 0.14 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
KN150670v1_-_61400 0.14

chr23_+_2482102 0.14 ENSDART00000126038
t-complex 1
chr24_-_42120772 0.14 ENSDART00000166413
ENSDART00000166414
signal sequence receptor, alpha
chr9_-_9106512 0.14

chr12_-_47699958 0.13 ENSDART00000171932
ENSDART00000168165
ENSDART00000161985
hematopoietically expressed homeobox
chr24_-_3751435 0.13 ENSDART00000139596
adenosine deaminase, RNA-specific, B2 (non-functional)
chr19_+_33235087 0.13 ENSDART00000052097
ENSDART00000052096
heat-responsive protein 12
chr16_+_7213161 0.13 ENSDART00000168830
ENSDART00000168274
ENSDART00000160383
ENSDART00000163281
BMP binding endothelial regulator
chr17_+_48734060 0.13 ENSDART00000178697
dishevelled associated activator of morphogenesis 2
chr20_-_9212177 0.13 ENSDART00000064140
YLP motif containing 1
chr7_-_32562435 0.13 ENSDART00000099872
ENSDART00000099871
ENSDART00000147554
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr22_-_120910 0.13

chr12_-_4497094 0.13 ENSDART00000163651
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr18_+_41570495 0.13 ENSDART00000169621
ENSDART00000162052
bromodomain adjacent to zinc finger domain, 1B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.4 GO:0061130 branching involved in pancreas morphogenesis(GO:0061114) pancreatic bud formation(GO:0061130) pancreas field specification(GO:0061131)
0.1 0.4 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.3 GO:0045905 positive regulation of translational termination(GO:0045905)
0.1 0.3 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.2 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.7 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.2 GO:0046379 renal water homeostasis(GO:0003091) renal water transport(GO:0003097) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.3 GO:0007141 male meiosis I(GO:0007141)
0.1 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.4 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.4 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.8 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 0.1 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.1 GO:0006210 thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.9 GO:0043049 otic placode formation(GO:0043049)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.0 0.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0009746 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0019184 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.1 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.1 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.0 0.5 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 1.2 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.0 0.1 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.4 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.6 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.1 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2 0.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.2 0.5 GO:0102344 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.4 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.4 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.6 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.3 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.5 GO:0050699 WW domain binding(GO:0050699)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 0.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.1 GO:0005035 death receptor activity(GO:0005035)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0050661 NADP binding(GO:0050661)
0.0 0.0 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport