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Results for hic1l+hic2

Z-value: 0.25

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Transcription factors associated with hic1l+hic2

Gene Symbol Gene ID Gene Info
hic1l
ENSDARG00000045660 hypermethylated in cancer 1 like
hic2
ENSDARG00000100497 hypermethylated in cancer 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hic2dr10_dc_chr10_-_3176372_31764500.476.8e-02Click!
hic1ldr10_dc_chr25_-_25480657_254806610.263.2e-01Click!

Activity profile of hic1l+hic2 motif

Sorted Z-values of hic1l+hic2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hic1l+hic2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr22_-_25592743 0.74 ENSDART00000110638
ENSDART00000172092
si:ch211-12h2.8
si:ch211-12h2.8
chr2_+_25281122 0.31 ENSDART00000025962
gyg1a
glycogenin 1a
chr2_+_24982557 0.25 ENSDART00000088346
mast3a
microtubule associated serine/threonine kinase 3a
chr2_+_24982611 0.21 ENSDART00000088346
mast3a
microtubule associated serine/threonine kinase 3a
chr8_-_49227232 0.21

chr2_+_24982203 0.21 ENSDART00000088346
mast3a
microtubule associated serine/threonine kinase 3a
chr8_-_49227286 0.20

chr23_-_6831711 0.19 ENSDART00000125393
FP102169.1
ENSDARG00000089210
chr5_-_24013767 0.18 ENSDART00000003957
tia1l
cytotoxic granule-associated RNA binding protein 1, like
chr21_+_33216466 0.18 ENSDART00000163808
ndst1b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
chr2_+_24982471 0.18 ENSDART00000088346
mast3a
microtubule associated serine/threonine kinase 3a
chr5_-_54097015 0.18

chr9_+_33409580 0.18 ENSDART00000100893
si:ch211-125e6.13
si:ch211-125e6.13
chr7_-_73620443 0.17 ENSDART00000158891
ENSDART00000111622
FP236812.3
ENSDARG00000079652
chr15_-_7340623 0.17 ENSDART00000161613
SLC7A1 (1 of many)
solute carrier family 7 member 1
chr17_+_51851738 0.16 ENSDART00000053422
ttll5
tubulin tyrosine ligase-like family, member 5
chr3_+_14362849 0.16 ENSDART00000161403
rab3db
RAB3D, member RAS oncogene family, b
chr1_+_29919378 0.16 ENSDART00000127670
bora
bora, aurora kinase A activator
chr2_-_30929469 0.16 ENSDART00000141669
myl12.2
myosin, light chain 12, genome duplicate 2
chr1_-_12575687 0.15

chr7_-_33414221 0.13

chr13_+_15669704 0.13 ENSDART00000146234
apopt1
apoptogenic 1, mitochondrial
chr2_+_24982268 0.12 ENSDART00000088346
mast3a
microtubule associated serine/threonine kinase 3a
chr22_-_20236913 0.12 ENSDART00000134485
si:dkey-110c1.10
si:dkey-110c1.10
chr21_+_33216833 0.12

chr6_-_19813235 0.12 ENSDART00000151152
si:dkey-19e4.5
si:dkey-19e4.5
chr7_+_22540012 0.12

chr21_+_33216675 0.11 ENSDART00000163808
ndst1b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
chr13_+_15669924 0.11 ENSDART00000146234
apopt1
apoptogenic 1, mitochondrial
chr21_+_33216241 0.11 ENSDART00000169972
ndst1b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b
chr7_-_21620707 0.11 ENSDART00000019699
mettl3
methyltransferase like 3
chr13_-_6150836 0.11 ENSDART00000092105
agpat5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr19_-_2148053 0.10 ENSDART00000020497
snx13
sorting nexin 13
chr7_-_21620664 0.10 ENSDART00000019699
mettl3
methyltransferase like 3
chr14_-_25636795 0.10

chr8_-_1154004 0.09 ENSDART00000149969
ENSDART00000016800
znf367
zinc finger protein 367
chr12_+_33793468 0.09 ENSDART00000130853
mfsd13a
major facilitator superfamily domain containing 13A
chr4_+_17666992 0.09 ENSDART00000066999
ccdc53
coiled-coil domain containing 53
chr22_-_21873054 0.09

chr20_-_54646114 0.08 ENSDART00000038745
yy1b
YY1 transcription factor b
chr19_+_21124187 0.08 ENSDART00000129730
rab5aa
RAB5A, member RAS oncogene family, a
chr7_-_46509861 0.08 ENSDART00000166565
tshz3b
teashirt zinc finger homeobox 3b
chr12_+_33793663 0.08 ENSDART00000004769
mfsd13a
major facilitator superfamily domain containing 13A
chr8_+_26838596 0.07

chr24_-_30924897 0.07 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr23_-_20199769 0.07 ENSDART00000147725
tktb
transketolase b
chr7_-_65012626 0.07

chr21_-_38670059 0.07 ENSDART00000065169
ENSDART00000113813
siah2l
seven in absentia homolog 2 (Drosophila)-like
chr22_-_5791916 0.07 ENSDART00000011076
cers5
ceramide synthase 5
chr3_-_30955799 0.06 ENSDART00000103421
zgc:153292
zgc:153292
chr18_-_16134258 0.06 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr5_+_25133592 0.06 ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr16_-_53978295 0.06 ENSDART00000158047
ZNRF2
zinc and ring finger 2
chr18_-_35590515 0.06 ENSDART00000150351
ryr1b
ryanodine receptor 1b (skeletal)
chr13_-_33077267 0.06 ENSDART00000146138
trip11
thyroid hormone receptor interactor 11
chr12_+_27445044 0.06 ENSDART00000133719
etv4
ets variant 4
chr7_+_20829815 0.06 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr11_-_11591523 0.06 ENSDART00000142208
zgc:110712
zgc:110712
chr5_-_34664282 0.06 ENSDART00000114981
ENSDART00000051279
ptcd2
pentatricopeptide repeat domain 2
chr6_-_19556328 0.06 ENSDART00000074256
ppp1r12c
protein phosphatase 1, regulatory subunit 12C
chr18_-_16134320 0.05 ENSDART00000061189
sspn
sarcospan (Kras oncogene-associated gene)
chr9_+_29832294 0.05 ENSDART00000023210
trim13
tripartite motif containing 13
chr9_-_22371512 0.05 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr1_+_29919729 0.05 ENSDART00000127670
bora
bora, aurora kinase A activator
chr23_-_20199837 0.05 ENSDART00000005021
tktb
transketolase b
chr11_-_41751050 0.04 ENSDART00000173086
zgc:175088
zgc:175088
chr6_+_20595096 0.04

chr25_-_13562597 0.04 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr9_-_29832812 0.04 ENSDART00000101177
spryd7b
SPRY domain containing 7b
chr17_+_13078286 0.04 ENSDART00000149779
gemin2
gem (nuclear organelle) associated protein 2
chr2_-_32404140 0.04 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr6_-_19812488 0.04 ENSDART00000151179
si:dkey-19e4.5
si:dkey-19e4.5
chr7_+_29681510 0.04 ENSDART00000173737
tpma
alpha-tropomyosin
chr7_+_29681196 0.04 ENSDART00000039657
tpma
alpha-tropomyosin
chr5_-_21520111 0.04

chr17_-_24872401 0.03 ENSDART00000135569
gale
UDP-galactose-4-epimerase
chr24_-_39970897 0.03 ENSDART00000134251
slc12a7b
solute carrier family 12 (potassium/chloride transporter), member 7b
chr2_+_11423028 0.03 ENSDART00000144982
lhx8a
LIM homeobox 8a
chr2_-_30929321 0.03 ENSDART00000141669
myl12.2
myosin, light chain 12, genome duplicate 2
chr25_+_11013469 0.03 ENSDART00000112789
AKAP13
A-kinase anchoring protein 13
chr15_-_29415309 0.03 ENSDART00000133117
tsku
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr4_-_9821525 0.03 ENSDART00000131357
ENSDART00000138321
parp12b
poly (ADP-ribose) polymerase family, member 12b
chr22_-_21872864 0.03 ENSDART00000158501
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr13_+_290930 0.03 ENSDART00000017854
lgi1a
leucine-rich, glioma inactivated 1a
chr12_+_31614163 0.03 ENSDART00000152973
RNF157
ring finger protein 157
chr25_-_19476079 0.02 ENSDART00000156811
si:ch211-59o9.10
si:ch211-59o9.10
chr25_-_13562558 0.02 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr25_-_13562693 0.02 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr6_-_27118157 0.02 ENSDART00000073883
dtymk
deoxythymidylate kinase (thymidylate kinase)
chr22_+_3989571 0.02 ENSDART00000170751
ticam1
toll-like receptor adaptor molecule 1
chr9_-_22402341 0.02 ENSDART00000110656
crygm2d20
crystallin, gamma M2d20
chr11_+_24110796 0.02 ENSDART00000089747
nfs1
NFS1 cysteine desulfurase
chr2_+_25281087 0.02 ENSDART00000025962
gyg1a
glycogenin 1a
chr13_+_18377514 0.02

chr17_+_8831186 0.02 ENSDART00000109573
akap6
A kinase (PRKA) anchor protein 6
chr19_+_48166365 0.02

chr22_-_5791865 0.02 ENSDART00000011076
cers5
ceramide synthase 5
chr21_-_14950265 0.02 ENSDART00000178507
mmp17a
matrix metallopeptidase 17a
chr17_+_32408151 0.02 ENSDART00000155519
si:ch211-139d20.3
si:ch211-139d20.3
chr20_+_31372117 0.02

chr20_-_28865097 0.01 ENSDART00000114611
sipa1l1
signal-induced proliferation-associated 1 like 1
chr17_-_43409222 0.01 ENSDART00000156033
itpk1b
inositol-tetrakisphosphate 1-kinase b
chr2_-_44402452 0.01 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr14_+_5852428 0.01 ENSDART00000157730
bscl2l
Bernardinelli-Seip congenital lipodystrophy 2, like
chr19_-_2147899 0.01 ENSDART00000020497
snx13
sorting nexin 13
chr3_-_11861502 0.01 ENSDART00000018159
ENSDARG00000011609
ENSDARG00000011609
chr5_-_25133229 0.01 ENSDART00000051566
zgc:101016
zgc:101016
chr17_+_52736844 0.01 ENSDART00000160507
meis2a
Meis homeobox 2a
chr8_+_8934762 0.01 ENSDART00000133137
bcap31
B-cell receptor-associated protein 31
chr25_+_16849382 0.01 ENSDART00000016591
fgf6a
fibroblast growth factor 6a
chr1_+_29919605 0.00 ENSDART00000127670
bora
bora, aurora kinase A activator
chr20_-_54645903 0.00 ENSDART00000038745
yy1b
YY1 transcription factor b
chr3_-_11861438 0.00 ENSDART00000018159
ENSDARG00000011609
ENSDARG00000011609
chr15_-_20795531 0.00 ENSDART00000114464
tpst1
tyrosylprotein sulfotransferase 1
chr22_+_9493668 0.00 ENSDART00000143953
strip1
striatin interacting protein 1
chr14_-_20766762 0.00 ENSDART00000164373
si:dkey-74k8.3
si:dkey-74k8.3
chr4_-_14916491 0.00 ENSDART00000067040
si:dkey-180p18.9
si:dkey-180p18.9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060853 forebrain radial glial cell differentiation(GO:0021861) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of mRNA modification(GO:0090365)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.1 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.1 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431) chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway