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Results for hlfb

Z-value: 0.40

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Transcription factors associated with hlfb

Gene Symbol Gene ID Gene Info
ENSDARG00000061011 HLF transcription factor, PAR bZIP family member b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hlfbdr10_dc_chr12_+_32044331_32044374-0.476.6e-02Click!

Activity profile of hlfb motif

Sorted Z-values of hlfb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hlfb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_24617667 0.56 ENSDART00000159531
lysophosphatidic acid receptor 3
chr18_-_16933517 0.49

chr6_+_50452131 0.42 ENSDART00000155051
myelocytomatosis oncogene homolog
chr6_+_16341787 0.40 ENSDART00000114667
zgc:161969
chr16_+_53391438 0.38 ENSDART00000010792
phosphatidylserine synthase 1a
chr1_-_35196892 0.35 ENSDART00000033566
SMAD family member 1
chr22_+_15946773 0.34 ENSDART00000144545
ring finger and CCCH-type domains 1a
chr13_-_10488076 0.33 ENSDART00000160561
si:ch73-54n14.2
chr15_-_38027363 0.33 ENSDART00000157550
si:dkey-238d18.15
chr23_-_18972097 0.31 ENSDART00000133826
ENSDARG00000057403
chr17_+_26946957 0.31 ENSDART00000114215
grainyhead-like transcription factor 3
chr10_+_39140943 0.31 ENSDART00000158245
si:ch73-1a9.3
chr25_-_18234069 0.30 ENSDART00000104496
dual specificity phosphatase 6
chr15_-_5912236 0.30

chr21_-_34809442 0.29 ENSDART00000029708
zgc:56585
chr15_-_29415309 0.29 ENSDART00000133117
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr6_-_26905146 0.28 ENSDART00000011863
high density lipoprotein binding protein a
chr5_+_6393799 0.26 ENSDART00000099417
ENSDARG00000076082
chr13_-_35908743 0.26 ENSDART00000133565
si:dkey-157l19.2
chr24_+_38783264 0.26 ENSDART00000154214
si:ch73-70c5.1
chr6_+_16342020 0.26 ENSDART00000114667
zgc:161969
chr17_-_20216303 0.26 ENSDART00000029380
BCL2/adenovirus E1B interacting protein 4
KN150442v1_-_37820 0.25 ENSDART00000158371
prothymosin, alpha b
chr5_-_68439806 0.24 ENSDART00000168213
methionine adenosyltransferase II, alpha b
chr6_+_12091402 0.24 ENSDART00000155101
si:dkey-276j7.3
chr4_-_22617898 0.21 ENSDART00000131402
golgin B1
chr8_-_15071283 0.21

chr10_+_32949485 0.21

chr15_-_5911817 0.21

chr15_-_5912105 0.21

chr10_+_18919823 0.21 ENSDART00000138334
protein phosphatase 2, regulatory subunit B, alpha b
chr22_+_11745592 0.20 ENSDART00000140272
keratin 96
chr19_-_3115104 0.19 ENSDART00000093146
block of proliferation 1
chr18_+_26916897 0.19 ENSDART00000050230
tetraspanin 3a
chr10_+_36718872 0.19 ENSDART00000063359
uncoupling protein 3
chr13_-_50940551 0.19

chr8_+_7937128 0.19 ENSDART00000137920
si:ch211-169p10.1
chr21_+_26486084 0.19 ENSDART00000134617
adenylosuccinate synthase, like
chr4_-_16555765 0.18 ENSDART00000033188
B-cell translocation gene 1, anti-proliferative
chr6_+_48349630 0.18 ENSDART00000064826
Mov10 RISC complex RNA helicase a
chr7_+_30222432 0.18 ENSDART00000027466
family with sequence similarity 63, member B
chr20_-_35343242 0.18 ENSDART00000113294
frizzled class receptor 3a
chr23_+_36608246 0.18 ENSDART00000113179
tetraspanin 31
KN150702v1_+_177145 0.18 ENSDART00000166225
ENSDARG00000102620
chr23_-_32239909 0.18

chr24_-_9153377 0.17 ENSDART00000082434
TGFB-induced factor homeobox 1
chr8_-_23172938 0.17 ENSDART00000141090
si:ch211-196c10.15
chr8_+_7937320 0.17 ENSDART00000137920
si:ch211-169p10.1
chr22_-_35967525 0.17 ENSDART00000176971
ENSDARG00000106725
chr6_+_42478185 0.17 ENSDART00000150226
macrophage stimulating 1 receptor a
chr20_-_36714338 0.17 ENSDART00000172395
ENSDART00000152856
enabled homolog (Drosophila)
chr14_-_30564987 0.17 ENSDART00000173451
si:ch211-126c2.4
chr1_-_11707244 0.16 ENSDART00000146067
sodium channel and clathrin linker 1
chr24_-_16878970 0.16 ENSDART00000106058
ENSDART00000106057
prostaglandin D2 synthase b, tandem duplicate 2
chr10_+_16914003 0.15 ENSDART00000177906
unc-13 homolog B
chr16_+_53391776 0.15 ENSDART00000010792
phosphatidylserine synthase 1a
chr1_-_39177682 0.15 ENSDART00000035739
transmembrane protein 134
chr21_+_18870471 0.15 ENSDART00000160185
sphingomyelin phosphodiesterase 4
chr21_+_17014240 0.15 ENSDART00000047201
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2b
chr21_-_32747483 0.15

chr19_-_22914516 0.15

chr6_+_23709605 0.15 ENSDART00000166921
glutamate-ammonia ligase (glutamine synthase) b
chr16_-_45950530 0.14 ENSDART00000060822
antifreeze protein type IV
chr7_+_45747622 0.14 ENSDART00000163991
cyclin E1
chr21_-_32747592 0.14

chr16_-_19762541 0.14 ENSDART00000141616
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr9_-_9754075 0.14 ENSDART00000092884
leucine rich repeat containing 58b
chr12_-_26445560 0.14 ENSDART00000138437
acyl-CoA synthetase family member 2
chr21_+_25588388 0.14 ENSDART00000134678
ENSDARG00000078256
chr24_+_28481885 0.14 ENSDART00000079770
ENSDART00000147063
ATP-binding cassette, sub-family A (ABC1), member 4a
chr6_-_32425011 0.13 ENSDART00000078908
ubiquitin specific peptidase 1
chr3_+_26092485 0.13 ENSDART00000128284
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr5_+_22470117 0.13 ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr19_+_4939815 0.13 ENSDART00000093402
cyclin-dependent kinase 12
chr7_+_45748086 0.13 ENSDART00000170294
cyclin E1
chr20_-_36714401 0.13 ENSDART00000165176
enabled homolog (Drosophila)
chr19_+_12066023 0.13 ENSDART00000130537
sperm associated antigen 1a
chr13_-_18064929 0.13 ENSDART00000079902
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr4_+_22146112 0.13 ENSDART00000158316
acyl-CoA synthetase short-chain family member 3
chr9_-_32489944 0.13 ENSDART00000078596
heat shock 60 protein 1
chr19_-_44459352 0.13 ENSDART00000151084
ubiquinol-cytochrome c reductase binding protein
chr14_+_6656015 0.13 ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr3_-_29760552 0.13 ENSDART00000014021
solute carrier family 25, member 39
KN150708v1_-_31573 0.13 ENSDART00000160040
solute carrier family 16, member 6a
chr11_-_44724371 0.13 ENSDART00000166501
calcium activated nucleotidase 1b
chr5_+_18837448 0.13

chr3_+_23963926 0.13 ENSDART00000138270
coatomer protein complex, subunit zeta 2
chr3_+_24564249 0.12 ENSDART00000111769
megakaryoblastic leukemia (translocation) 1a
chr24_-_38782898 0.12 ENSDART00000155542
ENSDARG00000097123
chr5_-_11309164 0.12 ENSDART00000132564
neurofibromin 2a (merlin)
chr22_+_11726312 0.12 ENSDART00000155366
keratin 96
chr19_+_16111610 0.12 ENSDART00000131319
CTP synthase 1a
chr7_+_22582619 0.12 ENSDART00000148502
chloride channel, voltage-sensitive 5b
chr13_-_50940520 0.12

chr3_+_7877162 0.12 ENSDART00000057434
ENSDART00000170291
hook microtubule-tethering protein 2
chr13_-_35908796 0.12 ENSDART00000084929
si:dkey-157l19.2
chr6_+_49552893 0.12 ENSDART00000022581
RAB22A, member RAS oncogene family
chr4_-_16556116 0.12 ENSDART00000033188
B-cell translocation gene 1, anti-proliferative
chr2_+_24152953 0.12 ENSDART00000131030
golgi reassembly stacking protein 1a
chr15_-_47277391 0.12 ENSDART00000151600
H3 histone, family 3B.1
chr23_-_14460361 0.12 ENSDART00000019620
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr18_-_14910429 0.11 ENSDART00000099701
selenoprotein O
chr16_-_6909034 0.11 ENSDART00000149206
ENSDART00000149778
myelin basic protein b
chr19_-_22914419 0.11

chr21_-_32748287 0.11 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr24_+_37911828 0.11 ENSDART00000131975
TEL2, telomere maintenance 2, homolog (S. cerevisiae)
chr10_-_5016621 0.11 ENSDART00000101414
heterogeneous nuclear ribonucleoprotein D
chr25_+_34340569 0.11 ENSDART00000157638
transmembrane protein 231
chr8_-_53165501 0.11 ENSDART00000135982
nuclear receptor subfamily 6, group A, member 1a
chr2_+_21698627 0.11 ENSDART00000133228
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr22_-_12305110 0.11 ENSDART00000123574
zinc finger, RAN-binding domain containing 3
chr19_+_42658273 0.11 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr10_-_2848524 0.11 ENSDART00000034555
ENSDART00000135708
ENSDART00000137180
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chr7_+_45747395 0.11 ENSDART00000163991
cyclin E1
chr25_-_6262259 0.11 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr7_+_45748011 0.10 ENSDART00000170294
cyclin E1
chr16_-_45943282 0.10 ENSDART00000133213
antifreeze protein type IV
chr12_+_26971687 0.10

chr24_-_9153339 0.10 ENSDART00000082434
TGFB-induced factor homeobox 1
chr5_-_13872772 0.10 ENSDART00000164698
ENSDARG00000104490
chr20_-_19632944 0.10 ENSDART00000125830
eukaryotic translation initiation factor 2B, subunit 4 delta
chr11_-_22211478 0.10 ENSDART00000065996
transmembrane protein 183A
chr6_-_32424706 0.10 ENSDART00000078908
ubiquitin specific peptidase 1
chr24_+_32610480 0.10 ENSDART00000132417
YME1-like 1a
chr5_-_11309124 0.10 ENSDART00000132564
neurofibromin 2a (merlin)
chr21_-_32747544 0.10

chr14_+_37203442 0.10

chr12_+_13167781 0.10 ENSDART00000160664
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr24_-_6304289 0.10 ENSDART00000140212
zgc:174877
chr22_-_15567180 0.10 ENSDART00000123125
tropomyosin 4a
chr21_+_4345107 0.09 ENSDART00000025612
phytanoyl-CoA dioxygenase domain containing 1
chr9_-_9754243 0.09 ENSDART00000092884
leucine rich repeat containing 58b
chr2_-_50126390 0.09 ENSDART00000083690
biliverdin reductase A
chr7_-_35136743 0.09 ENSDART00000074963
lysophosphatidylcholine acyltransferase 2
chr15_+_28370102 0.09 ENSDART00000175860
myosin Ic, paralog b
chr3_-_30754236 0.09 ENSDART00000109104
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr15_-_1800139 0.09 ENSDART00000093074
BUD23, rRNA methyltransferase and ribosome maturation factor
chr3_-_57459668 0.09 ENSDART00000003066
ENSDART00000125439
cytohesin 1a
chr7_-_37283707 0.09 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr1_-_49967146 0.09 ENSDART00000015591
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr9_+_27909662 0.09 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr2_+_16928379 0.09 ENSDART00000160641
ENSDART00000125413
5'-3' exoribonuclease 1
chr20_-_7303735 0.09 ENSDART00000100060
desmocollin 2 like
chr2_+_23196172 0.09 ENSDART00000145944
angiomotin like 2b
chr23_-_29952020 0.09 ENSDART00000058407
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr3_+_16514376 0.09 ENSDART00000013816
ENSDARG00000013161
chr18_+_5986137 0.09 ENSDART00000125725
si:ch1073-390k14.1
chr12_-_23008264 0.09 ENSDART00000152887
armadillo repeat containing 4
chr5_-_19691538 0.09 ENSDART00000139675
D-amino-acid oxidase, tandem duplicate 1
chr8_-_8659980 0.09 ENSDART00000046712
zgc:86609
chr21_-_4842528 0.09 ENSDART00000097796
ring finger protein 165a
chr18_-_14910358 0.09 ENSDART00000099701
selenoprotein O
chr25_+_13695348 0.09 ENSDART00000159278
zgc:92873
chr12_+_19159234 0.09 ENSDART00000153428
trinucleotide repeat containing 6b
chr22_+_10577272 0.09 ENSDART00000147975
RAD54-like 2 (S. cerevisiae)
chr3_-_40407003 0.09

chr12_+_31307634 0.09 ENSDART00000153179
zinc finger, DHHC-type containing 6
chr23_+_4773894 0.09 ENSDART00000172739
Raf-1 proto-oncogene, serine/threonine kinase a
chr5_+_2440622 0.09 ENSDART00000169404
heat shock protein 5
chr13_+_12651778 0.09 ENSDART00000090000
si:ch211-233a24.2
chr16_+_17706003 0.09

chr17_-_22552999 0.08 ENSDART00000141523
exonuclease 1
chr5_-_13872815 0.08 ENSDART00000164698
ENSDARG00000104490
chr9_-_306569 0.08 ENSDART00000166059
si:ch211-166e11.5
chr4_-_11978689 0.08

chr4_-_25807510 0.08 ENSDART00000122881
transmembrane and coiled-coil domain family 3
chr13_-_14798134 0.08 ENSDART00000020576
cell division cycle 25B
chr11_+_24583090 0.08 ENSDART00000135443
lysine (K)-specific demethylase 5Ba
chr19_+_12730277 0.08 ENSDART00000088917
RNA (guanine-7-) methyltransferase
chr23_-_39879096 0.08 ENSDART00000159519
ENSDARG00000102199
chr25_+_34340352 0.08 ENSDART00000163190
transmembrane protein 231
chr5_+_35839198 0.08 ENSDART00000102973
ENSDART00000103020
ectodysplasin A
chr22_+_15947127 0.08 ENSDART00000144545
ring finger and CCCH-type domains 1a
chr13_-_36486255 0.08 ENSDART00000160250
ENSDARG00000103360
chr10_+_23130414 0.08 ENSDART00000022170
listerin E3 ubiquitin protein ligase 1
chr5_+_22470177 0.08 ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr8_-_37217197 0.08 ENSDART00000178556
RNA binding motif protein 39b
chr7_+_22582561 0.08 ENSDART00000148502
chloride channel, voltage-sensitive 5b
chr12_-_26445609 0.08 ENSDART00000132737
ENSDART00000163931
acyl-CoA synthetase family member 2
chr18_-_14910497 0.08 ENSDART00000099701
selenoprotein O
chr1_+_15827083 0.08

chr12_-_22279713 0.08 ENSDART00000153194
si:dkey-38p12.3
chr13_-_25066650 0.08

chr13_+_29904913 0.08 ENSDART00000057525
DnaJ (Hsp40) homolog, subfamily B, member 12a
chr17_-_10682357 0.08 ENSDART00000064597
lectin, galactoside binding soluble 3b
chr8_-_22537415 0.08 ENSDART00000165640
porcupine homolog like
chr11_-_7068532 0.08 ENSDART00000112156
si:ch211-253b8.5
chr7_-_21620707 0.07 ENSDART00000019699
methyltransferase like 3
chr24_+_26183653 0.07 ENSDART00000003884
myoneurin
chr22_+_12306260 0.07

chr5_-_4507692 0.07 ENSDART00000067600
zinc finger and BTB domain containing 43
chr12_+_13167278 0.07 ENSDART00000092906
protein phosphatase 1, catalytic subunit, alpha isozyme b
chr11_+_16017857 0.07 ENSDART00000081054
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr14_-_31222400 0.07 ENSDART00000034979
motile sperm domain containing 1
chr18_-_16934756 0.07 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr10_+_6925373 0.07 ENSDART00000128866
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr25_+_34340139 0.07 ENSDART00000061996
transmembrane protein 231
chr24_+_32610430 0.07 ENSDART00000132417
YME1-like 1a
chr20_-_33584483 0.07 ENSDART00000177645
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr7_-_19390325 0.07 ENSDART00000163686
si:ch211-212k18.4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 0.3 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
0.1 0.3 GO:0003433 growth plate cartilage chondrocyte development(GO:0003431) chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.1 GO:0045041 interleukin-6 production(GO:0032635) regulation of interleukin-6 production(GO:0032675) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0090365 forebrain radial glial cell differentiation(GO:0021861) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of mRNA modification(GO:0090365)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.1 GO:0036088 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.4 GO:0050670 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0 0.1 GO:0042214 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.2 GO:0019856 pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0061355 Wnt protein secretion(GO:0061355)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0035552 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.0 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic cell cycle, embryonic(GO:0045448) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.0 0.1 GO:0015859 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.1 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0070266 necroptotic process(GO:0070266)
0.0 0.0 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.5 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.1 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.1 GO:0097345 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.0 0.0 GO:0034552 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.3 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.0 0.2 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0016422 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport