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Results for hmga1a

Z-value: 1.06

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Transcription factors associated with hmga1a

Gene Symbol Gene ID Gene Info
hmga1a
ENSDARG00000028335 high mobility group AT-hook 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmga1adr10_dc_chr23_-_3815492_38155560.562.5e-02Click!

Activity profile of hmga1a motif

Sorted Z-values of hmga1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hmga1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr23_+_25428372 2.88 ENSDART00000147440
fmnl3
formin-like 3
chr23_-_28420470 2.27 ENSDART00000145072
neurod4
neuronal differentiation 4
chr7_-_22685672 2.22 ENSDART00000101447
tnfsf10l
TNF superfamily member 10, like
chr3_+_61924544 2.22 ENSDART00000090370
noxo1a
NADPH oxidase organizer 1a
chr8_-_50992034 2.14 ENSDART00000004065
zgc:91909
zgc:91909
chr4_+_7406743 2.04 ENSDART00000168327
cald1a
caldesmon 1a
chr12_-_650506 2.04 ENSDART00000172651
sult2st2
sulfotransferase family 2, cytosolic sulfotransferase 2
chr5_-_55843553 1.95 ENSDART00000024207
tbx2a
T-box 2a
chr25_+_33833810 1.92 ENSDART00000073440
ENSDARG00000051762
ENSDARG00000051762
chr17_+_51430928 1.82 ENSDART00000170951
PXDN
peroxidasin
chr11_-_21422588 1.70

chr8_+_53173227 1.50 ENSDART00000131514
nadka
NAD kinase a
chr4_-_978592 1.44 ENSDART00000160902
naga
N-acetylgalactosaminidase, alpha
chr20_+_34497817 1.44 ENSDART00000061632
fam129aa
family with sequence similarity 129, member Aa
chr21_-_30144979 1.39 ENSDART00000065447
hnrnph1l
heterogeneous nuclear ribonucleoprotein H1, like
chr3_+_39821041 1.38

chr11_-_16840339 1.34 ENSDART00000122222
suclg2
succinate-CoA ligase, GDP-forming, beta subunit
chr21_+_22808694 1.32 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr12_-_10372055 1.31 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr5_-_20310793 1.28 ENSDART00000147639
si:ch211-225b11.1
si:ch211-225b11.1
chr19_-_46058954 1.24 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr5_-_37850885 1.23 ENSDART00000136428
ENSDART00000112487
chrne
cholinergic receptor, nicotinic, epsilon
chr25_+_558191 1.18 ENSDART00000126863
ENSDART00000166012
nell2a
neural EGFL like 2a
chr5_-_65103730 1.12 ENSDART00000169616
notch1b
notch 1b
chr10_+_42905246 1.11

chr6_-_48095609 1.07 ENSDART00000137458
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr23_-_45646407 1.03 ENSDART00000149291
ENSDARG00000036894
ENSDARG00000036894
chr2_+_1055716 1.00 ENSDART00000165477
AL935300.3
ENSDARG00000098661
chr7_-_22685631 0.96 ENSDART00000122113
tnfsf10l
TNF superfamily member 10, like
chr16_-_12345194 0.95 ENSDART00000114759
lpcat3
lysophosphatidylcholine acyltransferase 3
chr8_-_45043860 0.93 ENSDART00000138269
BX005065.1
ENSDARG00000092243
chr18_+_14627030 0.93 ENSDART00000080788
wfdc1
WAP four-disulfide core domain 1
chr17_-_50168910 0.92 ENSDART00000150024
acyp1
acylphosphatase 1, erythrocyte (common) type
chr7_-_35042805 0.90 ENSDART00000005053
slc12a4
solute carrier family 12 (potassium/chloride transporter), member 4
chr2_+_26183544 0.87 ENSDART00000078634
eif5a2
eukaryotic translation initiation factor 5A2
chr5_-_3489302 0.87

chr4_-_22950321 0.86 ENSDART00000050753
cd36
CD36 molecule (thrombospondin receptor)
chr7_+_48727042 0.83 ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr15_+_4079643 0.82

chr21_-_20728623 0.78 ENSDART00000135940
ENSDART00000002231
ghrb
growth hormone receptor b
chr19_-_43358940 0.78

chr13_+_42280697 0.77 ENSDART00000084354
cpeb3
cytoplasmic polyadenylation element binding protein 3
chr20_-_31841557 0.76

chr11_+_36827593 0.74 ENSDART00000124997
card19
caspase recruitment domain family, member 19
chr4_+_13569588 0.74 ENSDART00000136152
calua
calumenin a
chr2_+_26647894 0.73 ENSDART00000040278
efna2a
ephrin-A2a
chr1_-_54294303 0.72 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr25_-_1390537 0.71 ENSDART00000154130
CR354429.1
ENSDARG00000097252
chr19_-_46058895 0.70 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr5_-_19691538 0.69 ENSDART00000139675
dao.1
D-amino-acid oxidase, tandem duplicate 1
chr7_+_48726955 0.68 ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr10_+_20406765 0.66 ENSDART00000080395
golga7
golgin A7
chr12_+_22448972 0.65

chr3_+_36373519 0.64 ENSDART00000161652
si:dkeyp-72e1.9
si:dkeyp-72e1.9
chr5_+_32231368 0.60 ENSDART00000169358
ENSDARG00000095142
ENSDARG00000095142
chr7_+_32859453 0.59 ENSDART00000142450
zgc:153219
zgc:153219
chr3_+_25888520 0.58 ENSDART00000135389
foxred2
FAD-dependent oxidoreductase domain containing 2
chr23_-_3467855 0.58

chr1_+_1964902 0.56 ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr20_+_34497843 0.55 ENSDART00000061632
fam129aa
family with sequence similarity 129, member Aa
chr25_-_22821132 0.55

chr6_-_2089453 0.53 ENSDART00000022179
prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr23_+_3468073 0.52

chr11_-_12067922 0.51 ENSDART00000110117
socs7
suppressor of cytokine signaling 7
chr4_-_71730637 0.51 ENSDART00000174367
CABZ01032472.1
ENSDARG00000105801
chr11_-_18305730 0.50 ENSDART00000155474
fgd5a
FYVE, RhoGEF and PH domain containing 5a
chr1_-_54294382 0.49 ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr10_+_6120218 0.49 ENSDART00000166799
ENSDART00000157947
tln1
talin 1
chr14_-_33180554 0.49 ENSDART00000108827
c1galt1c1
C1GALT1-specific chaperone 1
chr24_-_37227441 0.49 ENSDART00000022999
ube2ib
ubiquitin-conjugating enzyme E2Ib
chr5_+_32231323 0.48 ENSDART00000169358
ENSDARG00000095142
ENSDARG00000095142
chr9_-_7419306 0.46 ENSDART00000125054
slc23a3
solute carrier family 23, member 3
chr15_+_46976241 0.45 ENSDART00000002384
phox2a
paired-like homeobox 2a
chr6_+_28303542 0.45 ENSDART00000136898
lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_10264593 0.41 ENSDART00000091726
fam78ba
family with sequence similarity 78, member B a
chr13_+_26943081 0.40 ENSDART00000146227
slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
KN149679v1_-_32359 0.40 ENSDART00000172177
surf4
surfeit gene 4
chr6_-_6965908 0.40 ENSDART00000041304
atg3
autophagy related 3
chr14_+_26461399 0.39 ENSDART00000125289
ahnak
AHNAK nucleoprotein
chr14_-_15393962 0.39 ENSDART00000161123
ENSDART00000167146
neurl1b
neuralized E3 ubiquitin protein ligase 1B
chr20_-_46345447 0.35 ENSDART00000100544
ENSDART00000152925
taar10
trace amine-associated receptor 10
chr17_-_21180028 0.35 ENSDART00000104708
abhd12
abhydrolase domain containing 12
chr5_+_52934865 0.35 ENSDART00000161682
BX323994.2
ENSDARG00000100423
chr4_+_75509365 0.34

chr11_-_18306222 0.34 ENSDART00000155474
fgd5a
FYVE, RhoGEF and PH domain containing 5a
chr14_-_2430754 0.34 ENSDART00000159004
si:ch73-233f7.8
si:ch73-233f7.8
chr4_+_17256021 0.34 ENSDART00000132933
casc1
cancer susceptibility candidate 1
chr5_-_1296190 0.34

chr17_+_31722419 0.33 ENSDART00000155073
arhgap5
Rho GTPase activating protein 5
chr11_+_44414503 0.32

chr24_-_35646129 0.31 ENSDART00000026578
ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr13_+_41791642 0.30 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr14_-_33180680 0.29 ENSDART00000052789
c1galt1c1
C1GALT1-specific chaperone 1
chr23_-_27707182 0.29 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr8_+_49986368 0.29 ENSDART00000156403
gfpt1
glutamine--fructose-6-phosphate transaminase 1
chr11_-_40416762 0.28 ENSDART00000166372
si:ch211-222l21.1
si:ch211-222l21.1
chr21_+_7807310 0.27 ENSDART00000023997
tbca
tubulin cofactor a
chr20_+_35352522 0.26 ENSDART00000002773
ENSDART00000137915
fam49a
family with sequence similarity 49, member A
chr25_+_15190474 0.24 ENSDART00000147572
ENSDART00000090330
hipk3a
homeodomain interacting protein kinase 3a
chr16_+_11833310 0.19 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr15_+_17094877 0.18 ENSDART00000062069
plin2
perilipin 2
chr5_-_51184375 0.14 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr7_-_20565207 0.13 ENSDART00000052977
cldn15a
claudin 15a
chr2_+_56705456 0.11

chr18_+_439454 0.11 ENSDART00000167841
ss18l2
synovial sarcoma translocation gene on chromosome 18-like 2
chr12_+_33818414 0.09 ENSDART00000085888
trim8b
tripartite motif containing 8b
chr1_+_19156170 0.08 ENSDART00000111454
ENSDARG00000080019
ENSDARG00000080019
chr7_-_32859341 0.04 ENSDART00000127006
ENSDART00000143768
mns1
meiosis-specific nuclear structural 1
chr3_-_61114604 0.02

chr21_+_21706999 0.01 ENSDART00000101700
pold3
polymerase (DNA-directed), delta 3, accessory subunit

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.7 2.0 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.5 3.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.4 0.9 GO:0044539 long-chain fatty acid import(GO:0044539)
0.3 1.3 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.3 1.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 0.9 GO:0045905 positive regulation of translational termination(GO:0045905)
0.3 0.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 1.4 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.2 2.3 GO:0001839 neural plate morphogenesis(GO:0001839)
0.2 0.7 GO:0070178 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.2 2.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.2 2.0 GO:0051923 sulfation(GO:0051923)
0.1 1.1 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 1.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.8 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 2.9 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 1.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.7 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 0.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.5 GO:0021703 locus ceruleus development(GO:0021703)
0.0 1.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0010890 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.4 GO:0060030 dorsal convergence(GO:0060030)
0.0 1.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 2.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.3 0.8 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.4 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.3 0.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.3 0.8 GO:0004903 growth hormone receptor activity(GO:0004903)
0.3 0.8 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 1.4 GO:0015925 galactosidase activity(GO:0015925)
0.2 3.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 1.2 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.3 GO:0070548 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) L-glutamine aminotransferase activity(GO:0070548)
0.1 2.0 GO:0017022 myosin binding(GO:0017022)
0.1 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.9 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.8 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 2.0 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 2.2 GO:0060090 binding, bridging(GO:0060090)
0.0 1.3 GO:0015293 symporter activity(GO:0015293)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination