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Results for hmx4

Z-value: 1.61

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Transcription factors associated with hmx4

Gene Symbol Gene ID Gene Info
hmx4
ENSDARG00000007941 H6 family homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hmx4dr10_dc_chr1_-_40208469_402085130.931.4e-07Click!

Activity profile of hmx4 motif

Sorted Z-values of hmx4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hmx4

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_25157675 6.50 ENSDART00000136984
fabp2
fatty acid binding protein 2, intestinal
chr11_-_5868257 6.24 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr13_+_7575753 4.71

chr6_+_17959219 4.32 ENSDART00000026448
evpla
envoplakin a
chr20_-_26632676 4.17 ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr5_-_7666964 3.77 ENSDART00000167643
slc1a3a
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr1_+_25662652 3.69 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr13_+_22528640 3.63 ENSDART00000078877
sncga
synuclein, gamma a
chr1_-_24747855 3.56 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr13_-_33696425 3.52 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr22_-_27082972 3.36 ENSDART00000077411
cxcl12b
chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)
chr11_-_25693072 3.25 ENSDART00000122011
kaznb
kazrin, periplakin interacting protein b
chr20_+_30894667 3.24 ENSDART00000145066
nhsl1b
NHS-like 1b
chr15_-_41288480 3.20 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr16_-_7525980 3.17 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr6_+_59788008 3.14

chr6_-_8501230 3.13 ENSDART00000143956
cavin2b
caveolae associated protein 2b
chr9_-_48098629 3.10

chr17_+_27417635 3.10 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr10_+_13251463 3.05 ENSDART00000000887
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr5_-_23829861 3.05 ENSDART00000051553
znf703
zinc finger protein 703
chr3_+_36282205 3.00 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr16_+_24032160 2.95 ENSDART00000103190
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr10_-_43826919 2.91 ENSDART00000039551
ENSDART00000160786
ENSDART00000099134
mef2ca
myocyte enhancer factor 2ca
chr7_-_37587227 2.90 ENSDART00000173552
adcy7
adenylate cyclase 7
chr9_-_53898524 2.81 ENSDART00000175619
ENSDART00000179009
CABZ01078244.2
ENSDARG00000107473
chr1_-_58606982 2.80 ENSDART00000158067
txndc11
thioredoxin domain containing 11
chr13_+_3533517 2.73 ENSDART00000018737
qkib
QKI, KH domain containing, RNA binding b
chr16_+_32605735 2.72 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr16_-_24602919 2.71 ENSDART00000147478
cadm4
cell adhesion molecule 4
chr2_+_49837788 2.60 ENSDART00000108861
sema4e
semaphorin 4e
chr20_-_29517770 2.56 ENSDART00000147464
ryr3
ryanodine receptor 3
chr6_-_23193752 2.55 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr22_+_12327849 2.52 ENSDART00000178678
FO704572.1
ENSDARG00000106890
KN150001v1_+_14939 2.49

chr2_-_21693984 2.49 ENSDART00000171699
hhatla
hedgehog acyltransferase-like, a
chr16_+_1227270 2.46

chr1_+_25662910 2.43 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr20_-_9107294 2.43 ENSDART00000140792
OMA1
OMA1 zinc metallopeptidase
chr17_+_27383737 2.39 ENSDART00000156756
FP017274.1
ENSDARG00000097369
chr10_+_7712522 2.37 ENSDART00000157608
fam136a
family with sequence similarity 136, member A
chr21_+_17731439 2.35 ENSDART00000124173
rxraa
retinoid X receptor, alpha a
KN150702v1_+_177145 2.35 ENSDART00000166225
CABZ01076674.1
ENSDARG00000102620
chr2_-_50244008 2.32 ENSDART00000029412
hecw1b
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1b
chr14_+_33382973 2.30 ENSDART00000132488
apln
apelin
chr3_+_54327353 2.29 ENSDART00000127487
eif3g
eukaryotic translation initiation factor 3, subunit G
chr1_+_9176411 2.28 ENSDART00000054848
pmm2
phosphomannomutase 2
chr7_-_33080261 2.28 ENSDART00000114041
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr12_-_10001043 2.25 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr23_-_9924987 2.23 ENSDART00000005015
prkcbp1l
protein kinase C binding protein 1, like
chr9_-_34491458 2.21 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr19_+_31046291 2.19 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr14_-_17353336 2.14

chr25_-_18234069 2.14 ENSDART00000104496
dusp6
dual specificity phosphatase 6
chr4_-_20435099 2.13 ENSDART00000055317
lrrc17
leucine rich repeat containing 17
chr9_-_41044622 2.07 ENSDART00000143384
si:dkey-95p16.1
si:dkey-95p16.1
chr7_-_64637419 2.07 ENSDART00000020456
mmp15b
matrix metallopeptidase 15b
chr1_-_22583661 2.05 ENSDART00000147800
rpl9
ribosomal protein L9
chr25_+_14411153 2.04 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr1_-_13547500 2.00 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr15_-_31635737 2.00 ENSDART00000156047
hmgb1b
high mobility group box 1b
chr22_+_21997000 1.98 ENSDART00000046174
gna15.1
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr7_+_28862183 1.98 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr13_+_27654900 1.97 ENSDART00000160550
CR356236.1
ENSDARG00000102040
chr16_+_5625301 1.95

chr6_+_59762717 1.95 ENSDART00000050457
zgc:65895
zgc:65895
chr23_+_24711233 1.90

chr21_+_5887486 1.88 ENSDART00000048399
slc4a4b
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr23_+_6043862 1.88

chr7_+_19300351 1.85 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr25_-_32344881 1.84 ENSDART00000012862
isl2a
ISL LIM homeobox 2a
chr14_+_13919450 1.84 ENSDART00000174760
nlgn3a
neuroligin 3a
chr22_+_12746080 1.83 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr13_+_3533426 1.83 ENSDART00000018737
qkib
QKI, KH domain containing, RNA binding b
chr7_+_13753344 1.80

chr4_+_5733160 1.79 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr19_+_7798512 1.79 ENSDART00000104719
ENSDART00000146747
tuft1b
tuftelin 1b
chr13_+_51663349 1.77

chr25_+_5232865 1.73

chr19_+_22478256 1.73 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr13_+_3533318 1.73 ENSDART00000018737
qkib
QKI, KH domain containing, RNA binding b
chr6_+_1873957 1.68

chr19_-_20614846 1.65 ENSDART00000155527
si:ch211-155k24.9
si:ch211-155k24.9
chr21_-_15578808 1.60 ENSDART00000136666
mmp11b
matrix metallopeptidase 11b
chr1_+_27174549 1.59 ENSDART00000102337
dnajb14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr13_+_25356184 1.56 ENSDART00000057689
bag3
BCL2-associated athanogene 3
chr16_-_20901879 1.54 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr8_+_53173227 1.54 ENSDART00000131514
nadka
NAD kinase a
chr25_-_13057808 1.54 ENSDART00000172571
smpd3
sphingomyelin phosphodiesterase 3, neutral
chr16_+_26673516 1.54 ENSDART00000141393
ptpn3
protein tyrosine phosphatase, non-receptor type 3
chr11_+_18823629 1.53

chr16_-_32605560 1.52

chr7_-_60525749 1.52 ENSDART00000136999
pcxb
pyruvate carboxylase b
chr1_-_58258428 1.50

chr15_-_47696481 1.47

chr3_-_19050721 1.46 ENSDART00000131503
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr10_-_43200499 1.46 ENSDART00000171494
ssbp2
single-stranded DNA binding protein 2
chr25_+_18487408 1.46 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr23_+_39713307 1.45 ENSDART00000109464
g0s2
G0/G1 switch 2
chr6_-_923434 1.45 ENSDART00000167390
zgc:113442
zgc:113442
chr17_+_53068731 1.45 ENSDART00000156774
dph6
diphthamine biosynthesis 6
chr10_+_9134634 1.45 ENSDART00000110443
fstb
follistatin b
chr1_+_157674 1.44 ENSDART00000152205
ENSDART00000160843
cul4a
cullin 4A
chr20_-_53629996 1.44 ENSDART00000141826
mettl24
methyltransferase like 24
chr16_-_33637966 1.42 ENSDART00000142965
BX511161.1
ENSDARG00000092272
chr9_-_53898458 1.42 ENSDART00000175619
ENSDART00000179009
CABZ01078244.2
ENSDARG00000107473
chr3_-_28078162 1.39 ENSDART00000165936
rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr18_+_45121016 1.39 ENSDART00000172328
gyltl1b
glycosyltransferase-like 1b
chr10_-_7712439 1.36 ENSDART00000159330
pcyox1
prenylcysteine oxidase 1
chr7_-_64637051 1.35 ENSDART00000020456
mmp15b
matrix metallopeptidase 15b
chr6_+_24299180 1.32 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
KN150207v1_-_1208 1.32 ENSDART00000171112
CABZ01112575.1
ENSDARG00000099354
chr16_+_20932876 1.28 ENSDART00000079343
jazf1b
JAZF zinc finger 1b
chr16_+_5625552 1.28

chr25_+_35782970 1.28 ENSDART00000125440
hist1h4l
histone 1, H4, like
chr19_+_12843381 1.27 ENSDART00000139909
mc5ra
melanocortin 5a receptor
chr8_-_3974357 1.26 ENSDART00000163754
ENSDART00000169474
mtmr3
myotubularin related protein 3
chr1_-_18695214 1.25

chr7_-_667744 1.24 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr14_-_33704021 1.22 ENSDART00000149396
ENSDART00000123607
cyfip2
cytoplasmic FMR1 interacting protein 2
chr19_-_13912235 1.21 ENSDART00000177773
epb41a
erythrocyte membrane protein band 4.1a
chr18_-_19467100 1.19 ENSDART00000060363
rpl4
ribosomal protein L4
chr16_+_13993746 1.19 ENSDART00000101304
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr20_-_53271601 1.18

chr6_-_39656043 1.17 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr21_-_8000406 1.16

chr23_-_21288972 1.16 ENSDART00000143206
megf6a
multiple EGF-like-domains 6a
chr18_-_36085063 1.16 ENSDART00000059352
ENSDART00000145177
exosc5
exosome component 5
chr3_+_55779906 1.16

chr1_-_54294303 1.16 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr14_-_33483075 1.16 ENSDART00000158870
si:dkey-76i15.1
si:dkey-76i15.1
chr23_+_200650 1.14

chr8_+_52633069 1.14 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr4_-_9591451 1.14 ENSDART00000114060
cdnf
cerebral dopamine neurotrophic factor
chr1_+_23093475 1.11

chr17_+_27706409 1.10 ENSDART00000123588
ENSDART00000170462
ENSDART00000169708
qkia
QKI, KH domain containing, RNA binding a
chr17_+_48349119 1.09 ENSDART00000019804
CABZ01043017.1
ENSDARG00000001937
chr7_+_25587183 1.09 ENSDART00000148780
mtmr1a
myotubularin related protein 1a
chr17_-_26849495 1.09 ENSDART00000153590
si:dkey-221l4.10
si:dkey-221l4.10
chr9_-_41982635 1.09 ENSDART00000144573
obsl1b
obscurin-like 1b
chr3_+_32234028 1.09 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr7_-_57030751 1.06

chr24_-_42226496 1.05 ENSDART00000163208
ENSDART00000112680
rmdn1
regulator of microtubule dynamics 1
chr13_-_36420228 1.04

chr14_+_33382672 1.04 ENSDART00000075312
apln
apelin
chr3_+_56507117 1.03 ENSDART00000154405
rac1b
ras-related C3 botulinum toxin substrate 1b (rho family, small GTP binding protein Rac1)
chr3_+_59491893 1.03 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr10_-_38206238 1.02 ENSDART00000174882
FP016248.1
ENSDARG00000107804
chr15_+_42393715 1.01

chr14_-_24744825 0.98 ENSDART00000159827
ENSDART00000131027
TMEM216
transmembrane protein 216
chr23_+_4385722 0.98 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
sgk2a
serum/glucocorticoid regulated kinase 2a
chr22_-_12130441 0.96 ENSDART00000146785
tmem163b
transmembrane protein 163b
chr6_+_39838929 0.94 ENSDART00000112637
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr23_-_26562635 0.94 ENSDART00000168052
magi3a
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr1_+_35462641 0.94 ENSDART00000053773
ENSDART00000147458
lsm6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr24_-_39132141 0.93

chr13_-_49546922 0.93

chr20_+_38129564 0.93 ENSDART00000032161
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr20_-_53630053 0.91 ENSDART00000135091
mettl24
methyltransferase like 24
chr23_+_22408855 0.90 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr8_-_24788837 0.89 ENSDART00000126220
alx3
ALX homeobox 3
chr18_+_37034218 0.88

chr3_-_22699157 0.88 ENSDART00000055659
cyb561
cytochrome b561
chr3_+_16116080 0.87 ENSDART00000122519
st8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr21_-_19789339 0.86

chr7_-_42972804 0.86 ENSDART00000054552
cdh8
cadherin 8
chr10_+_13251650 0.85 ENSDART00000136932
rassf6
Ras association (RalGDS/AF-6) domain family 6
chr14_-_46648350 0.84

chr7_+_22272746 0.84 ENSDART00000101528
chrnb1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr17_-_50343403 0.84 ENSDART00000140121
si:ch211-235i11.5
si:ch211-235i11.5
chr13_-_24248675 0.83 ENSDART00000046360
rhoua
ras homolog family member Ua
chr1_+_45148094 0.83 ENSDART00000048191
map2k7
mitogen-activated protein kinase kinase 7
chr16_-_28775103 0.83 ENSDART00000127753
adam15
ADAM metallopeptidase domain 15
chr20_-_32429358 0.81 ENSDART00000062982
foxo3b
forkhead box O3b
KN150001v1_+_15017 0.81

chr10_-_20681689 0.79

chr6_-_39655998 0.79 ENSDART00000155859
larp4ab
La ribonucleoprotein domain family, member 4Ab
chr6_-_23193873 0.79 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr6_-_34954414 0.78

chr25_+_9904821 0.78

chr17_+_31604804 0.76 ENSDART00000111629
cinp
cyclin-dependent kinase 2 interacting protein
chr16_+_4825665 0.73

chr13_+_7575720 0.73

chr23_-_26562855 0.72 ENSDART00000168052
magi3a
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr10_-_175160 0.72

chr16_+_54729975 0.71

chr13_+_41791642 0.71 ENSDART00000114741
polr1b
polymerase (RNA) I polypeptide B
chr6_+_46404650 0.70 ENSDART00000131203
ENSDART00000103472
ENSDART00000132845
ENSDART00000138567
ENSDART00000168440
pbrm1l
polybromo 1, like
chr11_-_2227358 0.69 ENSDART00000018131
hnrnpa1a
heterogeneous nuclear ribonucleoprotein A1a
chr24_-_16878970 0.69 ENSDART00000106058
ENSDART00000106057
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr4_-_4583387 0.69 ENSDART00000155287
rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr13_+_18401965 0.68 ENSDART00000136024
ftr14l
finTRIM family, member 14-like
chr23_+_17220363 0.67 ENSDART00000143420
BX927275.2
ENSDARG00000095017
chr12_-_26323696 0.67

chr24_-_20176227 0.67 ENSDART00000163683
map3k20
mitogen-activated protein kinase kinase kinase 20
chr16_-_54638972 0.66

chr17_+_25314291 0.66 ENSDART00000082319
tmem54a
transmembrane protein 54a
chr11_+_40567461 0.66 ENSDART00000160023
errfi1a
ERBB receptor feedback inhibitor 1a
chr3_-_33290990 0.65 ENSDART00000075493
ENSDART00000132293
ccdc103
coiled-coil domain containing 103
chr11_-_18656380 0.65 ENSDART00000080355
ENSDARG00000057708
ENSDARG00000057708

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.2 6.1 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
1.1 3.2 GO:0042756 drinking behavior(GO:0042756)
0.9 2.7 GO:0090171 chondrocyte morphogenesis(GO:0090171)
0.9 2.7 GO:0050748 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.8 3.4 GO:0097535 trigeminal sensory nucleus development(GO:0021730) lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.8 2.4 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.8 2.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.7 2.1 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
0.6 1.8 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.5 2.9 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.5 4.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.5 1.8 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.5 1.4 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.5 2.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.4 1.6 GO:0010657 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.4 5.0 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.3 3.0 GO:0034333 adherens junction assembly(GO:0034333)
0.3 2.9 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.3 3.2 GO:0001709 cell fate determination(GO:0001709)
0.3 2.9 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) regulation of osteoblast differentiation(GO:0045667)
0.2 3.2 GO:0097475 motor neuron migration(GO:0097475)
0.2 1.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 2.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 0.8 GO:0050687 negative regulation of response to biotic stimulus(GO:0002832) negative regulation of defense response to virus(GO:0050687)
0.2 2.1 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 0.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 2.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 0.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 3.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 1.2 GO:0001964 startle response(GO:0001964)
0.1 2.3 GO:0032526 response to retinoic acid(GO:0032526)
0.1 4.3 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 2.3 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.9 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 1.4 GO:0046686 response to cadmium ion(GO:0046686)
0.1 1.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.5 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 2.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.3 GO:0070285 pigment cell development(GO:0070285)
0.1 1.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.1 GO:0031641 regulation of myelination(GO:0031641)
0.1 1.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 2.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 2.7 GO:0001885 endothelial cell development(GO:0001885)
0.1 0.3 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.7 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.3 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.6 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 0.8 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 6.5 GO:0033993 response to lipid(GO:0033993)
0.1 7.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 1.0 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.1 0.3 GO:0060359 sperm motility(GO:0030317) response to alkaloid(GO:0043279) response to ammonium ion(GO:0060359) cellular response to ammonium ion(GO:0071242)
0.0 0.4 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.6 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 2.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 2.1 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.0 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 1.3 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.4 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 3.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 1.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.6 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 2.9 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.6 GO:0007416 synapse assembly(GO:0007416)
0.0 2.3 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.9 GO:0022900 electron transport chain(GO:0022900)
0.0 0.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 1.5 GO:0031016 pancreas development(GO:0031016)
0.0 2.5 GO:0042127 regulation of cell proliferation(GO:0042127)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.4 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.3 1.2 GO:0016586 RSC complex(GO:0016586)
0.2 3.0 GO:0016363 nuclear matrix(GO:0016363)
0.2 2.1 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.5 GO:0043679 axon terminus(GO:0043679)
0.2 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 0.7 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 2.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.9 GO:0005688 U6 snRNP(GO:0005688)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 3.1 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 4.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.9 GO:0071564 npBAF complex(GO:0071564)
0.1 5.0 GO:0031012 extracellular matrix(GO:0031012)
0.1 4.3 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 17.7 GO:0005615 extracellular space(GO:0005615)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.6 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.5 GO:0009986 cell surface(GO:0009986)
0.0 2.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 2.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 3.4 GO:0005576 extracellular region(GO:0005576)
0.0 1.8 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.9 GO:0030658 transport vesicle membrane(GO:0030658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
1.2 6.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.2 3.5 GO:1903136 cuprous ion binding(GO:1903136)
0.9 4.3 GO:0019215 intermediate filament binding(GO:0019215)
0.8 2.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.7 2.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.6 1.8 GO:0016841 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.6 6.5 GO:0005504 fatty acid binding(GO:0005504)
0.5 3.2 GO:0031704 apelin receptor binding(GO:0031704)
0.5 2.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.4 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.4 2.6 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 3.4 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.4 1.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 1.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 1.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 3.1 GO:0005080 protein kinase C binding(GO:0005080)
0.2 9.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.2 2.1 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 2.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.2 2.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821) mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 2.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 1.4 GO:0048185 activin binding(GO:0048185)
0.1 0.9 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1 2.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0051192 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.1 1.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 2.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.5 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 5.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 2.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0070402 NADPH binding(GO:0070402)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 2.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.5 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 3.2 GO:0042393 histone binding(GO:0042393)
0.0 2.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.1 GO:0008083 growth factor activity(GO:0008083)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 2.1 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 1.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 2.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 2.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 2.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 2.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 5.5 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 0.5 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 3.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression