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Results for hnf1a

Z-value: 2.70

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Transcription factors associated with hnf1a

Gene Symbol Gene ID Gene Info
hnf1a
ENSDARG00000009470 HNF1 homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf1adr10_dc_chr8_+_39768744_397687800.931.3e-07Click!

Activity profile of hnf1a motif

Sorted Z-values of hnf1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_-_99353 14.15 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr8_+_933677 11.62 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr22_-_17570306 11.13 ENSDART00000139361
gpx4a
glutathione peroxidase 4a
chr24_-_39722595 10.46 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr2_-_18157106 10.00 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr12_-_6144233 9.47 ENSDART00000152292
a1cf
apobec1 complementation factor
chr22_-_23598571 9.16 ENSDART00000166800
cfhl4
complement factor H like 4
chr1_+_9367672 8.61 ENSDART00000144756
fgb
fibrinogen beta chain
chr21_-_23271127 8.47 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr16_-_42990753 8.10 ENSDART00000149317
hfe2
hemochromatosis type 2
chr1_-_11439671 8.03 ENSDART00000164817
mtp
microsomal triglyceride transfer protein
chr20_+_18841440 7.67 ENSDART00000174532
fam167ab
family with sequence similarity 167, member Ab
chr7_-_25623974 7.58 ENSDART00000173602
cd99l2
CD99 molecule-like 2
chr19_-_22802777 7.56 ENSDART00000151234
eppk1
epiplakin 1
chr14_-_46651359 7.10 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr5_+_31745031 6.97 ENSDART00000147132
c9
complement component 9
chr14_-_20760787 6.84

chr14_-_31128891 6.51

chr25_+_30746445 6.49 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr6_+_7742042 6.42 ENSDART00000112290
ENSDART00000062740
palm3
paralemmin 3
chr21_+_25199691 6.41 ENSDART00000168140
ENSDART00000112783
tmem45b
transmembrane protein 45B
chr3_-_16100715 6.18 ENSDART00000146699
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr7_+_26978970 6.14 ENSDART00000150068
sox6
SRY (sex determining region Y)-box 6
chr17_+_3879416 5.88 ENSDART00000151849
hao1
hydroxyacid oxidase (glycolate oxidase) 1
chr12_+_31558667 5.72 ENSDART00000152971
dnmbp
dynamin binding protein
chr13_-_23536022 5.46

chr9_-_43178744 5.43

chr15_-_24987099 5.37

chr23_+_32409339 5.10 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr13_-_40600924 5.07 ENSDART00000099847
ENSDART00000057046
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr16_-_9785057 5.03 ENSDART00000113724
mal2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr21_-_44610563 5.01 ENSDART00000099528
spry4
sprouty homolog 4 (Drosophila)
chr18_+_9413588 5.00 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr3_+_15355472 4.98 ENSDART00000141714
nupr1
nuclear protein 1
chr11_-_23079615 4.98 ENSDART00000125024
golt1a
golgi transport 1A
chr3_+_45375639 4.86 ENSDART00000162799
crb3a
crumbs homolog 3a
chr15_-_16075172 4.85

chr15_+_27431469 4.60 ENSDART00000122101
tbx2b
T-box 2b
chr22_+_3136570 4.52 ENSDART00000163327
rpl36
ribosomal protein L36
chr23_+_24711233 4.42

chr4_-_885413 4.40 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr13_-_11404389 4.40 ENSDART00000018155
adss
adenylosuccinate synthase
chr9_+_21340251 4.35 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr5_-_55843553 4.30 ENSDART00000024207
tbx2a
T-box 2a
chr16_+_55351732 4.23 ENSDART00000109391
CABZ01052290.1
ENSDARG00000077559
chr20_-_7303735 4.03 ENSDART00000100060
dsc2l
desmocollin 2 like
chr10_+_7296895 4.03 ENSDART00000161506
fut10
fucosyltransferase 10
chr10_-_8074713 4.00 ENSDART00000140476
atp6v0a2a
ATPase, H+ transporting, lysosomal V0 subunit a2a
chr8_-_47811709 4.00 ENSDART00000115050
ENSDART00000133669
kank3
KN motif and ankyrin repeat domains 3
chr24_-_16895179 3.90 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr13_-_42453219 3.78 ENSDART00000135172
fam83ha
family with sequence similarity 83, member Ha
chr6_+_30469823 3.71 ENSDART00000121492
FP236735.1
ENSDARG00000087805
chr22_+_12746080 3.67 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr14_-_46650724 3.64

chr20_-_7303804 3.62 ENSDART00000100060
dsc2l
desmocollin 2 like
chr5_-_62747812 3.54

chr6_-_39346614 3.52 ENSDART00000104074
zgc:158846
zgc:158846
chr22_-_23641813 3.39 ENSDART00000159622
cfh
complement factor H
chr14_+_8198019 3.34 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr24_+_9124068 3.32

chr1_-_22160662 3.30 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr6_+_7741987 3.20 ENSDART00000112290
ENSDART00000062740
palm3
paralemmin 3
chr17_-_13072982 3.15 ENSDART00000178859
CABZ01047998.1
ENSDARG00000105945
chr12_+_15624640 3.13 ENSDART00000079803
nmt1b
N-myristoyltransferase 1b
chr5_-_54151518 3.07

chr11_-_40415291 2.97

chr20_-_25582221 2.95 ENSDART00000157559
si:dkey-183n20.15
si:dkey-183n20.15
chr17_-_35004687 2.85

chr2_+_49683715 2.80 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr15_-_27431216 2.80 ENSDART00000155933
AL954322.2
ENSDARG00000097072
chr22_+_34738389 2.78 ENSDART00000154372
hoga1
4-hydroxy-2-oxoglutarate aldolase 1
chr23_+_31505372 2.76 ENSDART00000138350
rps12
ribosomal protein S12
chr5_+_3721680 2.70 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr8_+_1122000 2.67 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr5_+_44722544 2.65 ENSDART00000084411
adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr1_-_18809429 2.61 ENSDART00000124260
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr3_-_34208423 2.57 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr15_+_9321225 2.56 ENSDART00000055554
slc37a4a
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr5_-_62747914 2.54

chr3_+_54506912 2.53 ENSDART00000135913
si:ch211-74m13.1
si:ch211-74m13.1
chr9_-_1457681 2.53 ENSDART00000124777
ENSDART00000093412
osbpl6
oxysterol binding protein-like 6
chr25_-_7346766 2.50 ENSDART00000170050
cdkn1cb
cyclin-dependent kinase inhibitor 1Cb
chr21_-_99497 2.46 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr11_-_37730181 2.44 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr11_-_27455348 2.43 ENSDART00000045942
phf2
PHD finger protein 2
chr3_+_45375698 2.43 ENSDART00000162799
crb3a
crumbs homolog 3a
chr24_+_19842162 2.36 ENSDART00000123031
CR381686.3
ENSDARG00000094073
chr21_+_43674754 2.35 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr7_+_39934376 2.35 ENSDART00000173742
ncapg2
non-SMC condensin II complex, subunit G2
chr6_+_54213569 2.31 ENSDART00000128456
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr14_+_721560 2.26 ENSDART00000165014
klb
klotho beta
chr17_+_15026344 2.19 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr8_+_26502909 2.17 ENSDART00000046863
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr7_-_25624212 2.17 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr5_-_30114979 2.16 ENSDART00000016758
ftr82
finTRIM family, member 82
chr9_-_43736549 2.13 ENSDART00000140526
znf385b
zinc finger protein 385B
chr8_+_13069277 2.08 ENSDART00000138433
itgb4
integrin, beta 4
chr17_+_15025997 2.04 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr3_+_23607148 2.03 ENSDART00000143981
hoxb3a
homeobox B3a
chr5_-_9162684 2.01

chr9_-_14137664 2.00 ENSDART00000132747
prkag3b
protein kinase, AMP-activated, gamma 3b non-catalytic subunit
chr3_+_15355424 1.99 ENSDART00000141714
nupr1
nuclear protein 1
chr21_-_44109455 1.95 ENSDART00000044599
oatx
organic anion transporter X
chr10_-_41742329 1.95 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr3_+_40028301 1.95 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr10_-_1799784 1.92 ENSDART00000058627
epb41l4a
erythrocyte membrane protein band 4.1 like 4A
chr15_-_23532475 1.85 ENSDART00000148804
pdzd3a
PDZ domain containing 3a
chr2_-_44893769 1.84 ENSDART00000041806
acsm3
acyl-CoA synthetase medium-chain family member 3
chr9_+_33177527 1.81 ENSDART00000174533
vangl1
VANGL planar cell polarity protein 1
chr17_-_14956738 1.78

chr9_-_48152388 1.73

chr7_-_25624128 1.68 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr10_+_4476558 1.68 ENSDART00000125299
plk2a
polo-like kinase 2a (Drosophila)
chr5_-_37285874 1.67 ENSDART00000132152
si:ch211-139a5.9
si:ch211-139a5.9
chr5_+_8843643 1.66 ENSDART00000149417
ENSDART00000061616
tal2
T-cell acute lymphocytic leukemia 2
chr13_+_48327287 1.65 ENSDART00000168596
si:ch1073-268j14.1
si:ch1073-268j14.1
chr2_-_24661477 1.61 ENSDART00000078975
ENSDART00000155677
trnau1apb
tRNA selenocysteine 1 associated protein 1b
chr14_-_32543646 1.60 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr16_-_8711133 1.60

chr1_+_25974174 1.59 ENSDART00000152144
si:dkey-25o16.2
si:dkey-25o16.2
chr14_-_46650551 1.59

chr24_-_8592157 1.58 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr16_+_11833310 1.51 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr20_-_7141247 1.46 ENSDART00000160910
si:ch211-121a2.4
si:ch211-121a2.4
chr2_-_5492583 1.46 ENSDART00000152907
si:ch1073-184j22.2
si:ch1073-184j22.2
chr17_+_15026176 1.43 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr24_+_23646663 1.43 ENSDART00000146580
mybl1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr4_-_30124515 1.38

chr14_-_46650640 1.27

chr1_+_25974337 1.26 ENSDART00000152617
si:dkey-25o16.2
si:dkey-25o16.2
chr23_+_25930072 1.26 ENSDART00000124103
hnf4a
hepatocyte nuclear factor 4, alpha
KN149681v1_-_46883 1.23

chr9_+_30909291 1.22 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr20_-_25537241 1.20 ENSDART00000153266
itsn2a
intersectin 2a
chr9_+_30183691 1.16 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr16_+_26573825 1.16

chr9_+_30909382 1.13 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr10_+_20151165 1.13 ENSDART00000142708
dmtn
dematin actin binding protein
chr4_+_74835204 1.06 ENSDART00000172647
ENSDART00000174351
zgc:113209
zgc:113209
chr1_+_25974264 1.04 ENSDART00000152785
si:dkey-25o16.2
si:dkey-25o16.2
chr5_+_67157870 1.00 ENSDART00000162301
ENSDART00000159386
si:ch211-271b14.1
si:ch211-271b14.1
chr22_-_17570275 1.00 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr18_+_9413668 0.99 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr22_-_23721742 0.94 ENSDART00000163228
cfh
complement factor H
chr24_+_14569372 0.93 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr6_+_32478052 0.90

chr18_+_10957421 0.86 ENSDART00000166561
ttc38
tetratricopeptide repeat domain 38
chr3_+_26603352 0.86 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr3_+_52645074 0.85 ENSDART00000058958
atp13a1
ATPase type 13A1
chr12_-_20251183 0.82 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr20_-_7303680 0.82 ENSDART00000100060
dsc2l
desmocollin 2 like
chr19_+_20690151 0.73 ENSDART00000151059
oxnad1
oxidoreductase NAD-binding domain containing 1
chr5_-_54151599 0.72

chr17_+_11950934 0.70

chr4_-_70791859 0.69 ENSDART00000125726
si:ch211-161m3.6
si:ch211-161m3.6
chr11_-_27832530 0.66 ENSDART00000172937
BX248318.1
ENSDARG00000104418
chr19_-_15324958 0.64 ENSDART00000055619
phactr4a
phosphatase and actin regulator 4a
chr3_-_31583910 0.63 ENSDART00000051542
ccdc47
coiled-coil domain containing 47
chr7_-_10318692 0.60 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr8_+_13069233 0.56 ENSDART00000138433
itgb4
integrin, beta 4
chr7_-_61591422 0.55 ENSDART00000110328
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr21_+_39055276 0.50 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr8_+_13069201 0.50 ENSDART00000138433
itgb4
integrin, beta 4
chr11_-_6071086 0.48 ENSDART00000122262
babam1
BRISC and BRCA1 A complex member 1
chr5_-_28888704 0.47

chr12_+_20545413 0.46 ENSDART00000144804
mxra7
matrix-remodelling associated 7
chr3_+_30967192 0.41 ENSDART00000153354
BX004999.1
ENSDARG00000096792
chr7_+_41033650 0.40 ENSDART00000016660
ENSDARG00000016964
ENSDARG00000016964
chr11_+_6138968 0.40 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr14_-_46650934 0.40 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr10_+_2948774 0.35 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr5_-_28888658 0.33

chr9_+_28877812 0.33 ENSDART00000101319
zgc:162396
zgc:162396
chr18_+_5005303 0.32

chr25_-_36621405 0.27 ENSDART00000128108
urahb
urate (5-hydroxyiso-) hydrolase b
chr10_+_20151082 0.27 ENSDART00000142708
dmtn
dematin actin binding protein
chr21_-_99613 0.14 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr2_-_27953540 0.14 ENSDART00000040555
tgs1
trimethylguanosine synthase 1
chr9_-_30692456 0.01

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.7 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
3.3 10.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
3.0 8.9 GO:0072025 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
2.3 6.8 GO:1902855 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855)
2.1 8.5 GO:0032481 positive regulation of type I interferon production(GO:0032481)
1.5 5.9 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
1.4 7.0 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
1.3 7.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.2 3.7 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
1.2 6.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.1 8.5 GO:0002159 desmosome assembly(GO:0002159)
0.9 6.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.9 8.6 GO:0070527 platelet aggregation(GO:0070527)
0.8 5.0 GO:0045056 transcytosis(GO:0045056)
0.8 2.4 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.8 3.1 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.7 5.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.7 9.5 GO:0016556 mRNA modification(GO:0016556)
0.6 4.0 GO:0036065 fucosylation(GO:0036065)
0.6 3.3 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.5 5.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.5 1.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 2.8 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.4 2.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.4 1.6 GO:0015865 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) purine-containing compound transmembrane transport(GO:0072530) mitochondrial ATP transmembrane transport(GO:1990544)
0.4 2.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.4 2.6 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.4 4.0 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.3 2.3 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.3 2.5 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.3 1.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 6.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.2 3.8 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.2 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 14.2 GO:0033993 response to lipid(GO:0033993)
0.1 11.0 GO:0006979 response to oxidative stress(GO:0006979)
0.1 0.5 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.1 1.6 GO:0050935 iridophore differentiation(GO:0050935)
0.1 0.4 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 2.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 4.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.1 4.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 2.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.4 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 1.7 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 2.3 GO:0030261 chromosome condensation(GO:0030261)
0.0 1.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 1.4 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 14.1 GO:0022610 cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.0 2.7 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 2.8 GO:0072001 kidney development(GO:0001822) renal system development(GO:0072001)
0.0 1.9 GO:0031032 actomyosin structure organization(GO:0031032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0005577 fibrinogen complex(GO:0005577)
1.4 7.0 GO:0005579 membrane attack complex(GO:0005579)
0.7 14.9 GO:0045095 keratin filament(GO:0045095)
0.5 4.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.5 2.3 GO:0000796 condensin complex(GO:0000796)
0.3 2.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 4.9 GO:0030057 desmosome(GO:0030057)
0.2 2.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 1.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 4.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.9 GO:0008305 integrin complex(GO:0008305)
0.1 2.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 4.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 6.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 5.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 5.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.8 GO:0022626 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.1 2.2 GO:0005795 Golgi stack(GO:0005795)
0.1 2.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.9 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.7 GO:0000922 spindle pole(GO:0000922)
0.0 8.5 GO:0030054 cell junction(GO:0030054)
0.0 2.6 GO:0043235 receptor complex(GO:0043235)
0.0 13.5 GO:0005576 extracellular region(GO:0005576)
0.0 10.0 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 16.7 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
4.0 12.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
2.3 11.3 GO:0019215 intermediate filament binding(GO:0019215)
1.7 5.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.3 4.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.2 3.7 GO:0016841 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
1.1 11.6 GO:0005504 fatty acid binding(GO:0005504)
0.9 2.7 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.8 3.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.7 10.2 GO:0010181 FMN binding(GO:0010181)
0.6 1.9 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.6 8.2 GO:0038191 neuropilin binding(GO:0038191)
0.6 3.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.5 5.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 2.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 1.6 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.4 4.0 GO:0051117 ATPase binding(GO:0051117)
0.3 2.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 5.6 GO:0030371 translation repressor activity(GO:0030371)
0.3 1.9 GO:0043495 protein anchor(GO:0043495)
0.2 5.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 2.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.8 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.2 2.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 9.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 10.0 GO:0008201 heparin binding(GO:0008201)
0.2 1.8 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 2.5 GO:0015248 sterol transporter activity(GO:0015248)
0.1 8.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 2.9 GO:0005178 integrin binding(GO:0005178)
0.1 2.0 GO:0016208 AMP binding(GO:0016208)
0.1 5.1 GO:0031406 carboxylic acid binding(GO:0031406)
0.1 2.6 GO:0019955 cytokine binding(GO:0019955)
0.1 2.4 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 7.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 20.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 3.3 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 2.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.5 6.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 2.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 6.1 PID BMP PATHWAY BMP receptor signaling
0.1 2.3 PID FGF PATHWAY FGF signaling pathway
0.1 1.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
1.4 8.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.2 10.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.5 16.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 7.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.4 8.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 4.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 1.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.2 10.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 2.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 2.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 7.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 8.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 5.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression