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Results for hnf1ba+hnf1bb

Z-value: 2.65

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Transcription factors associated with hnf1ba+hnf1bb

Gene Symbol Gene ID Gene Info
hnf1ba
ENSDARG00000006615 HNF1 homeobox Ba
hnf1bb
ENSDARG00000022295 HNF1 homeobox Bb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf1bbdr10_dc_chr21_+_38770125_387701370.924.3e-07Click!
hnf1badr10_dc_chr15_-_16076874_160769520.792.8e-04Click!

Activity profile of hnf1ba+hnf1bb motif

Sorted Z-values of hnf1ba+hnf1bb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf1ba+hnf1bb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_25623974 11.53 ENSDART00000173602
cd99l2
CD99 molecule-like 2
chr2_-_18157106 10.58 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr16_-_42990753 10.05 ENSDART00000149317
hfe2
hemochromatosis type 2
chr21_-_23271127 9.60 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr19_-_5435448 9.21 ENSDART00000027701
krt92
keratin 92
chr1_-_11439671 8.73 ENSDART00000164817
mtp
microsomal triglyceride transfer protein
chr12_-_6144233 8.65 ENSDART00000152292
a1cf
apobec1 complementation factor
chr1_+_9367672 7.66 ENSDART00000144756
fgb
fibrinogen beta chain
chr24_-_39722595 7.23 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr21_-_20291707 7.17 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr5_+_31745031 7.14 ENSDART00000147132
c9
complement component 9
chr14_-_20760787 7.08

chr15_-_18159904 7.02 ENSDART00000170874
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr6_+_7742042 6.74 ENSDART00000112290
ENSDART00000062740
palm3
paralemmin 3
chr3_-_16100715 6.61 ENSDART00000146699
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr15_+_35184996 6.51 ENSDART00000086954
ENSDART00000161594
sesn3
sestrin 3
chr14_-_31128891 6.37

chr8_-_985673 6.26 ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr13_-_23536022 6.17

chr19_+_20199890 5.44 ENSDART00000161019
hoxa4a
homeobox A4a
chr10_+_25407847 5.38 ENSDART00000047541
bach1b
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr16_-_9785057 5.15 ENSDART00000113724
mal2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr5_-_40707316 4.97 ENSDART00000161932
npr3
natriuretic peptide receptor 3
chr8_-_53508979 4.93 ENSDART00000158789
chdh
choline dehydrogenase
chr13_-_18704185 4.85 ENSDART00000146795
lzts2a
leucine zipper, putative tumor suppressor 2a
chr24_-_6048914 4.70 ENSDART00000146830
ENSDART00000021981
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr14_-_46651359 4.65 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr9_+_38814714 4.60 ENSDART00000114728
znf148
zinc finger protein 148
chr9_+_21340251 4.44 ENSDART00000133903
hao2
hydroxyacid oxidase 2 (long chain)
chr2_+_2374651 4.26 ENSDART00000132500
c8a
complement component 8, alpha polypeptide
chr23_+_32409339 4.24 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr8_-_47811709 4.19 ENSDART00000115050
ENSDART00000133669
kank3
KN motif and ankyrin repeat domains 3
chr24_+_35899507 4.14 ENSDART00000122408
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr20_-_35938683 4.03 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr22_+_20436009 4.00 ENSDART00000135984
onecut3a
one cut homeobox 3a
chr6_+_30469823 3.99 ENSDART00000121492
FP236735.1
ENSDARG00000087805
chr20_-_25582221 3.96 ENSDART00000157559
si:dkey-183n20.15
si:dkey-183n20.15
chr5_-_11562856 3.94 ENSDART00000026749
nipsnap1
nipsnap homolog 1 (C. elegans)
chr17_-_13072982 3.85 ENSDART00000178859
CABZ01047998.1
ENSDARG00000105945
chr5_+_44722544 3.82 ENSDART00000084411
adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr23_+_24557956 3.72

chr7_-_25624212 3.71 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr6_+_7741987 3.59 ENSDART00000112290
ENSDART00000062740
palm3
paralemmin 3
chr6_+_60060297 3.53 ENSDART00000178621
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr23_+_24711233 3.50

chr1_-_22160662 3.49 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr15_+_28269289 3.47 ENSDART00000077736
vtna
vitronectin a
chr21_+_43674754 3.46 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr22_-_23641813 3.38 ENSDART00000159622
cfh
complement factor H
chr24_-_16895179 3.29 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr15_+_42626315 3.25

chr14_+_38313985 3.22 ENSDART00000148938
rnasel3
ribonuclease like 3
chr25_+_23326562 3.14

chr1_-_18809429 3.13 ENSDART00000124260
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr5_+_3721680 3.11 ENSDART00000140537
dhrs11a
dehydrogenase/reductase (SDR family) member 11a
chr17_+_15026344 3.07 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr7_-_25624128 3.05 ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr8_+_15216833 3.02 ENSDART00000141185
slc5a9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr2_-_24661477 3.01 ENSDART00000078975
ENSDART00000155677
trnau1apb
tRNA selenocysteine 1 associated protein 1b
chr17_+_15025997 3.01 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr11_-_37730181 2.96 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr13_-_40600924 2.91 ENSDART00000099847
ENSDART00000057046
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr6_+_54213569 2.89 ENSDART00000128456
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr24_+_25767893 2.83 ENSDART00000143099
map3k15
mitogen-activated protein kinase kinase kinase 15
chr14_+_721560 2.82 ENSDART00000165014
klb
klotho beta
chr5_-_54151518 2.73

chr1_-_58258428 2.71

chr5_+_37254520 2.64 ENSDART00000051222
ins
preproinsulin
chr7_-_72027936 2.55 ENSDART00000161914
slc35c1
solute carrier family 35 (GDP-fucose transporter), member C1
chr21_+_39918070 2.39 ENSDART00000135235
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr12_-_3903961 2.25 ENSDART00000134292
ENSDARG00000021154
ENSDARG00000021154
chr24_+_9124068 2.22

chr3_+_40028301 2.17 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr25_+_23326630 2.15

chr17_+_15026176 2.11 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr4_-_885413 2.11 ENSDART00000022668
aim1b
crystallin beta-gamma domain containing 1b
chr5_-_30114979 2.09 ENSDART00000016758
ftr82
finTRIM family, member 82
chr7_+_26788074 2.07 ENSDART00000173919
plekha7b
pleckstrin homology domain containing, family A member 7b
chr11_-_44738307 2.04 ENSDART00000167540
afmid
arylformamidase
chr22_+_34738389 2.01 ENSDART00000154372
hoga1
4-hydroxy-2-oxoglutarate aldolase 1
chr24_+_19842162 1.88 ENSDART00000123031
CR381686.3
ENSDARG00000094073
chr9_-_14137664 1.87 ENSDART00000132747
prkag3b
protein kinase, AMP-activated, gamma 3b non-catalytic subunit
chr4_+_74835204 1.84 ENSDART00000172647
ENSDART00000174351
zgc:113209
zgc:113209
chr23_+_25930072 1.79 ENSDART00000124103
hnf4a
hepatocyte nuclear factor 4, alpha
chr18_-_48498261 1.78 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr9_+_30909291 1.74 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr8_-_19166630 1.73

chr11_-_27832530 1.68 ENSDART00000172937
BX248318.1
ENSDARG00000104418
chr13_-_36409205 1.65 ENSDART00000043312
srsf5a
serine/arginine-rich splicing factor 5a
chr16_-_8711133 1.63

chr23_+_28843683 1.51 ENSDART00000132179
masp2
mannan-binding lectin serine peptidase 2
chr9_+_30183691 1.50 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr24_+_23646663 1.47 ENSDART00000146580
mybl1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr9_+_30909382 1.46 ENSDART00000146115
klf12b
Kruppel-like factor 12b
chr5_-_42304154 1.37 ENSDART00000112807
cxcl20
chemokine (C-X-C motif) ligand 20
chr16_-_22903823 1.32

chr3_+_26603352 1.30 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr10_-_41742329 1.28 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr1_+_25974174 1.18 ENSDART00000152144
si:dkey-25o16.2
si:dkey-25o16.2
chr6_-_43030291 1.17 ENSDART00000149637
glyctk
glycerate kinase
chr8_+_26502909 1.17 ENSDART00000046863
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr2_+_51087570 1.11

chr5_-_37285874 1.09 ENSDART00000132152
si:ch211-139a5.9
si:ch211-139a5.9
chr24_-_21768269 1.05 ENSDART00000081178
c1qtnf9
C1q and TNF related 9
chr19_-_15324958 1.03 ENSDART00000055619
phactr4a
phosphatase and actin regulator 4a
chr8_+_30690195 1.02 ENSDART00000005345
upb1
ureidopropionase, beta
chr5_+_23625065 0.98 ENSDART00000029719
si:ch211-114c12.2
si:ch211-114c12.2
chr6_+_32478052 0.97

chr1_+_25974337 0.96 ENSDART00000152617
si:dkey-25o16.2
si:dkey-25o16.2
chr25_+_3221696 0.95 ENSDART00000104888
slc35b4
solute carrier family 35, member B4
chr24_+_14569372 0.93 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr14_-_46650551 0.90

chr22_-_23721742 0.89 ENSDART00000163228
cfh
complement factor H
chr3_+_52645074 0.84 ENSDART00000058958
atp13a1
ATPase type 13A1
chr17_+_11950934 0.79

chr15_+_44442345 0.79 ENSDART00000028011
msantd4
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr1_+_25974264 0.79 ENSDART00000152785
si:dkey-25o16.2
si:dkey-25o16.2
chr24_+_25767966 0.77 ENSDART00000143099
map3k15
mitogen-activated protein kinase kinase kinase 15
chr7_-_10318692 0.76 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr25_-_36621405 0.74 ENSDART00000128108
urahb
urate (5-hydroxyiso-) hydrolase b
chr7_-_72027580 0.73 ENSDART00000161914
slc35c1
solute carrier family 35 (GDP-fucose transporter), member C1
chr14_-_46650640 0.71

chr25_-_3633631 0.67 ENSDART00000159335
ENSDART00000088077
zgc:158398
zgc:158398
chr22_+_10630419 0.65 ENSDART00000105835
tusc2b
tumor suppressor candidate 2b
chr17_+_5740225 0.63 ENSDART00000019905
fndc4b
fibronectin type III domain containing 4b
chr17_-_22047445 0.57 ENSDART00000156872
ttbk1b
tau tubulin kinase 1b
chr21_+_39055276 0.56 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr3_+_55994886 0.56

chr5_-_54151599 0.53

chr20_+_34814623 0.49 ENSDART00000034252
pnocb
prepronociceptin b
chr7_-_32562435 0.49 ENSDART00000099872
ENSDART00000099871
ENSDART00000147554
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr5_-_11562934 0.46 ENSDART00000026749
nipsnap1
nipsnap homolog 1 (C. elegans)
chr24_-_21740552 0.42

chr20_+_31173383 0.40 ENSDART00000136255
otofa
otoferlin a
chr17_-_17928974 0.38 ENSDART00000090447
hhipl1
HHIP-like 1
chr15_+_38319701 0.35 ENSDART00000122134
stim1a
stromal interaction molecule 1a
chr10_+_2948774 0.33 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr2_+_51087643 0.32

chr17_-_51804002 0.18 ENSDART00000103350
ENSDART00000017329
numb
numb homolog (Drosophila)
chr9_+_28877812 0.17 ENSDART00000101319
zgc:162396
zgc:162396
chr17_+_15025962 0.13 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr19_+_8225252 0.11 ENSDART00000147218
efna3a
ephrin-A3a
chr12_-_3904030 0.09 ENSDART00000134292
ENSDARG00000021154
ENSDARG00000021154
chr10_-_42302932 0.09 ENSDART00000076693
ENSDART00000073631
stambpa
STAM binding protein a
chr14_-_46650934 0.08 ENSDART00000163316
CR383676.1
ENSDARG00000099970
chr2_-_27953540 0.03 ENSDART00000040555
tgs1
trimethylguanosine synthase 1
chr21_-_26678542 0.02 ENSDART00000053794
banf1
barrier to autointegration factor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:0097374 sensory neuron axon guidance(GO:0097374)
2.4 9.6 GO:0032481 positive regulation of type I interferon production(GO:0032481)
2.3 11.4 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
1.3 4.0 GO:0050864 regulation of B cell activation(GO:0050864)
1.2 8.4 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
1.0 3.9 GO:0019532 oxalate transport(GO:0019532)
0.9 3.5 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.9 5.1 GO:0045056 transcytosis(GO:0045056)
0.8 5.9 GO:0048769 sarcomerogenesis(GO:0048769)
0.8 7.7 GO:0070527 platelet aggregation(GO:0070527)
0.7 2.6 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858) regulation of feeding behavior(GO:0060259)
0.6 5.1 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.6 4.9 GO:0051013 microtubule severing(GO:0051013)
0.6 4.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.6 8.6 GO:0016556 mRNA modification(GO:0016556)
0.5 3.3 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.5 3.0 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.4 3.1 GO:0038093 B cell differentiation(GO:0030183) Fc receptor signaling pathway(GO:0038093)
0.4 2.9 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.4 3.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.4 3.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.3 2.0 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.3 8.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.3 1.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.3 1.5 GO:0006956 complement activation(GO:0006956)
0.3 5.0 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.2 1.4 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.2 0.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.6 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 3.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.8 GO:0035999 folic acid-containing compound biosynthetic process(GO:0009396) tetrahydrofolate interconversion(GO:0035999)
0.1 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.9 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 3.6 GO:0006814 sodium ion transport(GO:0006814)
0.0 21.0 GO:0022610 cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.0 3.8 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 5.4 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.0 GO:0008643 carbohydrate transport(GO:0008643)
0.0 1.1 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 3.5 GO:0006955 immune response(GO:0006955)
0.0 0.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 2.9 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.2 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 4.6 GO:0030097 hemopoiesis(GO:0030097)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0005577 fibrinogen complex(GO:0005577)
2.3 11.4 GO:0005579 membrane attack complex(GO:0005579)
0.6 5.1 GO:0061700 GATOR2 complex(GO:0061700)
0.5 5.9 GO:0031430 M band(GO:0031430)
0.5 7.0 GO:0045180 basal cortex(GO:0045180)
0.2 1.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.9 GO:0032587 ruffle membrane(GO:0032587)
0.1 9.2 GO:0005882 intermediate filament(GO:0005882)
0.1 4.9 GO:0030496 midbody(GO:0030496)
0.1 8.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 5.1 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 9.7 GO:0030054 cell junction(GO:0030054)
0.0 15.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 17.2 GO:0005739 mitochondrion(GO:0005739)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 8.6 GO:0005576 extracellular region(GO:0005576)
0.0 33.3 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.9 3.5 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.8 3.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.6 5.1 GO:0070728 leucine binding(GO:0070728)
0.6 1.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.5 5.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 2.4 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.4 3.0 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.4 1.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.4 8.3 GO:0030371 translation repressor activity(GO:0030371)
0.4 2.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.4 5.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 2.0 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 4.4 GO:0010181 FMN binding(GO:0010181)
0.3 3.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 0.8 GO:0016882 cyclo-ligase activity(GO:0016882)
0.2 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 0.9 GO:0004061 arylformamidase activity(GO:0004061)
0.2 4.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 4.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2 10.6 GO:0008201 heparin binding(GO:0008201)
0.2 8.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.2 1.4 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.2 3.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 4.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 6.6 GO:0031406 carboxylic acid binding(GO:0031406)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.9 GO:0016208 AMP binding(GO:0016208)
0.1 3.1 GO:0019955 cytokine binding(GO:0019955)
0.1 5.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 3.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 2.6 GO:0005179 hormone activity(GO:0005179)
0.1 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.0 3.2 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.3 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 9.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 20.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.0 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 8.2 PID BMP PATHWAY BMP receptor signaling
0.1 2.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 20.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.6 4.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
1.5 7.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 7.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.3 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 2.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 6.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 2.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 4.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2 2.8 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.2 3.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 7.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 3.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 8.6 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 4.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1