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Results for hnf4a+hnf4b

Z-value: 1.18

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Transcription factors associated with hnf4a+hnf4b

Gene Symbol Gene ID Gene Info
ENSDARG00000021494 hepatocyte nuclear factor 4, alpha
ENSDARG00000104742 hepatic nuclear factor 4, beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf4adr10_dc_chr23_+_25930072_259301580.581.9e-02Click!

Activity profile of hnf4a+hnf4b motif

Sorted Z-values of hnf4a+hnf4b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4a+hnf4b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_23999029 5.19 ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr3_-_31672763 3.83 ENSDART00000028270
glial fibrillary acidic protein
chr14_+_20809272 3.24 ENSDART00000139865
aldolase b, fructose-bisphosphate
chr25_+_21732255 3.22 ENSDART00000027393
creatine kinase, mitochondrial 1
chr22_+_37934447 3.12 ENSDART00000076082
fetuin B
chr6_-_39315024 3.09 ENSDART00000012644
keratin 4
chr25_+_5162045 3.01 ENSDART00000169540
ENSDARG00000101164
chr2_+_24881103 2.90 ENSDART00000144149
angiopoietin-like 4
chr21_-_37509454 2.86 ENSDART00000175126
fibroblast growth factor receptor 4
chr16_+_55167489 2.86 ENSDART00000149795
nuclear receptor subfamily 0, group B, member 2a
chr16_+_24032160 2.84 ENSDART00000103190
apolipoprotein A-IV b, tandem duplicate 2
chr14_+_6122948 2.80 ENSDART00000149783
ENSDART00000148461
ATP-binding cassette, sub-family A (ABC1), member 1B
chr2_-_10667156 2.69 ENSDART00000081196
scinderin like b
chr12_-_5085227 2.68 ENSDART00000160729
retinol binding protein 4, plasma
chr24_-_33817169 2.64 ENSDART00000079292
caveolae associated protein 4b
chr2_+_30932612 2.59 ENSDART00000132450
ENSDART00000137012
myomesin 1a (skelemin)
chr12_+_27032862 2.56

chr7_+_23843682 2.49 ENSDART00000173899
mitochondrial ribosomal protein L52
chr4_-_16461748 2.43 ENSDART00000128835
wu:fc23c09
chr21_+_25199691 2.28 ENSDART00000168140
ENSDART00000112783
transmembrane protein 45B
chr2_+_3701942 2.27 ENSDART00000132572
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr20_+_2255204 2.26 ENSDART00000137579
si:ch73-18b11.2
chr2_+_32036450 2.12 ENSDART00000140776
ENSDARG00000091946
chr17_+_1058137 2.11

chr12_+_29994735 2.09 ENSDART00000042572
ENSDART00000153025
actin binding LIM protein 1b
chr2_-_20941256 2.07 ENSDART00000114199
si:ch211-267e7.3
chr1_-_18695214 2.05

chr5_+_51392394 2.04 ENSDART00000143276
SET binding protein 1
chr23_-_15442032 2.01 ENSDART00000082060
ENSDARG00000078145
chr10_-_6453139 2.01 ENSDART00000168549
carbonic anhydrase IX
chr13_+_16130212 1.95 ENSDART00000125813
molybdenum cofactor sulfurase
chr15_-_26619404 1.91 ENSDART00000150152
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr17_-_30685367 1.83 ENSDART00000114358
zgc:194392
chr20_+_23643050 1.80 ENSDART00000168690
palladin, cytoskeletal associated protein
chr1_-_46015367 1.79 ENSDART00000074519
karyopherin alpha 3 (importin alpha 4)
chr7_-_54407681 1.78 ENSDART00000162795
cyclin D1
chr11_+_30073930 1.76 ENSDART00000127075
UDP glucuronosyltransferase 1 family, polypeptide B1
chr4_+_11174186 1.73 ENSDART00000138661
tetraspanin 11
chr5_+_8415025 1.71 ENSDART00000046440
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr22_-_20101177 1.71 ENSDART00000138688
cAMP responsive element binding protein 3-like 3a
KN149726v1_+_1094 1.68

chr16_+_17061069 1.68 ENSDART00000111074
si:ch211-120k19.1
chr7_+_25649559 1.68 ENSDART00000026295
arrestin, beta 2b
chr11_+_30048913 1.66

chr8_+_7740132 1.63 ENSDART00000171325
transcription factor binding to IGHM enhancer 3a
chr7_-_64637419 1.62 ENSDART00000020456
matrix metallopeptidase 15b
chr1_+_52739724 1.59 ENSDART00000159220
uncoupling protein 1
chr7_+_31567166 1.55 ENSDART00000099785
ENSDART00000122506
myosin binding protein C, cardiac
chr12_-_31342432 1.54 ENSDART00000148603
acyl-CoA synthetase long-chain family member 5
chr2_-_37974443 1.54 ENSDART00000034595
cerebellin 10
chr13_+_28689749 1.51 ENSDART00000101653
ENSDARG00000062790
chr11_+_8119829 1.50 ENSDART00000011183
protein kinase, cAMP-dependent, catalytic, beta a
chr3_-_60973097 1.47 ENSDART00000055062
parvalbumin 1
chr17_+_443558 1.45 ENSDART00000171386
zgc:194887
chr19_+_31944725 1.44 ENSDART00000136289
transmembrane protein 64
chr3_-_10342940 1.43 ENSDART00000124419
ENSDARG00000101154
chr24_-_33817036 1.31 ENSDART00000079292
caveolae associated protein 4b
chr22_+_16293900 1.29 ENSDART00000164161
oxysterol binding protein-like 1A
chr12_-_27032151 1.27 ENSDART00000153365
ENSDARG00000096750
chr8_+_1760968 1.27 ENSDART00000021820
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr23_+_17853977 1.26

chr15_-_1225595 1.23

chr3_-_23513177 1.22 ENSDART00000078425
even-skipped-like1
chr22_+_16471319 1.22 ENSDART00000014330
immediate early response 5
chr5_-_1325831 1.21

chr16_-_32059848 1.18 ENSDART00000138701
glutathione S-transferase kappa 1
chr11_+_36983626 1.15 ENSDART00000170209
interleukin 17 receptor C
chr11_+_30482530 1.10 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr5_-_3562233 1.08 ENSDART00000143250
si:ch1073-189o9.1
chr13_-_22713071 1.07 ENSDART00000142738
phenazine biosynthesis like protein domain containing
chr7_-_64637051 1.07 ENSDART00000020456
matrix metallopeptidase 15b
chr15_-_23532475 1.05 ENSDART00000148804
PDZ domain containing 3a
chr13_-_37001997 1.05 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr13_+_45843396 1.05 ENSDART00000005195
ENSDART00000074547
BSD domain containing 1
chr11_+_11217547 1.05 ENSDART00000087105
myomesin 2a
chr14_+_24637864 1.04 ENSDART00000170871
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr8_-_11512545 1.03 ENSDART00000133932
si:ch211-248e11.2
chr24_+_20815964 1.02 ENSDART00000133008
si:ch211-161h7.8
chr21_-_12958161 1.01 ENSDART00000133517
si:dkey-228b2.5
chr16_-_12345194 1.00 ENSDART00000114759
lysophosphatidylcholine acyltransferase 3
chr21_-_30074456 0.99 ENSDART00000014223
solute carrier family 23 (ascorbic acid transporter), member 1
chr5_+_29327363 0.97

chr2_+_37985514 0.97 ENSDART00000149224
apolipoprotein L, 1
chr18_+_17622557 0.97 ENSDART00000046891
cholesteryl ester transfer protein, plasma
chr20_+_27194162 0.95 ENSDART00000024595
ubiquitin protein ligase E3 component n-recognin 7
chr13_-_40600924 0.95 ENSDART00000099847
ENSDART00000057046
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr15_-_1880456 0.94 ENSDART00000102410
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_+_30049412 0.94

chr5_+_29327479 0.93

chr2_-_44429891 0.92 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
myelin protein zero
chr5_+_51392688 0.91 ENSDART00000143276
SET binding protein 1
chr6_+_53428775 0.90 ENSDART00000165067
abhydrolase domain containing 14B
chr2_-_56531858 0.89 ENSDART00000113589
glutathione peroxidase 4b
chr12_+_2412047 0.88 ENSDART00000112032
Rho GTPase activating protein 22
chr18_-_16934961 0.87 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr20_+_22766887 0.86 ENSDART00000147520
ligand of numb-protein X 1
chr13_+_16130123 0.86 ENSDART00000170855
molybdenum cofactor sulfurase
chr25_+_3884499 0.84 ENSDART00000104926
ENSDARG00000058108
chr7_-_20201358 0.83 ENSDART00000174001
netrin 5
chr9_-_41982635 0.82 ENSDART00000144573
obscurin-like 1b
chr13_+_45843567 0.82 ENSDART00000005195
ENSDART00000074547
BSD domain containing 1
chr16_-_54638972 0.80

chr17_-_16079935 0.80

chr10_+_21693418 0.79 ENSDART00000160754
protocadherin 1 gamma 1
chr7_-_51186389 0.77 ENSDART00000174328
Rho GTPase activating protein 6
chr9_+_8919542 0.76 ENSDART00000134954
carbohydrate kinase domain containing
chr2_-_37967102 0.74 ENSDART00000163165
ENSDARG00000105027
chr11_-_30117563 0.74 ENSDART00000078387
peroxisomal trans-2-enoyl-CoA reductase
chr12_+_29994880 0.74 ENSDART00000042572
ENSDART00000153025
actin binding LIM protein 1b
chr8_+_6533379 0.72 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
KN149817v1_+_2207 0.72

chr23_-_3816492 0.70 ENSDART00000136394
high mobility group AT-hook 1a
chr18_-_7184884 0.69 ENSDART00000135587
CD9 molecule a
chr14_-_32543646 0.69 ENSDART00000105726
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr20_+_22766918 0.68 ENSDART00000147520
ligand of numb-protein X 1
chr7_-_20201693 0.66 ENSDART00000174001
netrin 5
chr7_+_30779987 0.66 ENSDART00000148347
tight junction protein 1a
chr8_+_39768744 0.66 ENSDART00000018862
HNF1 homeobox a
chr22_+_24617667 0.65 ENSDART00000159531
lysophosphatidic acid receptor 3
chr6_-_2501966 0.65 ENSDART00000155109
hydroxypyruvate isomerase
chr5_-_44243476 0.65 ENSDART00000161408
fructose-1,6-bisphosphatase 1a
chr10_+_33956052 0.64

chr21_-_36886505 0.64 ENSDART00000113678
WW and C2 domain containing 1
chr18_-_7441136 0.62 ENSDART00000101250
si:dkey-30c15.13
chr13_+_50062513 0.60 ENSDART00000124142
ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr14_+_721560 0.60 ENSDART00000165014
klotho beta
chr11_+_6754335 0.60 ENSDART00000104292
phosphodiesterase 4C, cAMP-specific b
chr21_-_37509396 0.59 ENSDART00000100286
fibroblast growth factor receptor 4
chr24_-_36840203 0.59 ENSDART00000135142
si:ch73-334d15.1
chr8_+_36888422 0.58

chr4_-_19705018 0.58 ENSDART00000100974
staphylococcal nuclease and tudor domain containing 1
chr8_+_13069277 0.56 ENSDART00000138433
integrin, beta 4
chr2_+_23600656 0.56

chr23_-_5080531 0.56

chr17_-_42778156 0.55 ENSDART00000140549
NK2 homeobox 2a
chr13_+_32676922 0.55 ENSDART00000085252
PQ loop repeat containing 3
chr5_-_63487161 0.54 ENSDART00000048395
cardiac myosin light chain-1
chr19_+_31944573 0.54 ENSDART00000136289
transmembrane protein 64
chr16_-_25691856 0.52 ENSDART00000077447
ENSDART00000131528
zgc:110410
chr1_+_11485480 0.51 ENSDART00000132560
STRA6-like
chr20_-_3074139 0.50 ENSDART00000046641
mitogen-activated protein kinase kinase kinase 5
chr15_+_21399127 0.49 ENSDART00000154914
ENSDARG00000097950
chr10_+_26786051 0.49 ENSDART00000100329
coagulation factor IXb
chr22_-_17570275 0.48 ENSDART00000099056
glutathione peroxidase 4a
chr22_-_10744909 0.47 ENSDART00000081156
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr1_-_51658383 0.45 ENSDART00000132638
ENSDARG00000059948
chr20_-_3074186 0.44 ENSDART00000046641
mitogen-activated protein kinase kinase kinase 5
chr10_-_17484971 0.44

chr20_-_52526843 0.43 ENSDART00000132941
si:ch1073-287p18.1
chr1_-_11377949 0.43 ENSDART00000103406
phospholipase A2, group XIIA
chr10_+_10780578 0.42 ENSDART00000170147
ENSDART00000004181
solute carrier family 27 (fatty acid transporter), member 4
chr12_-_944349 0.42 ENSDART00000128188
diacylglycerol lipase, beta
chr1_-_11377650 0.42 ENSDART00000143628
phospholipase A2, group XIIA
chr12_+_16832804 0.42

chr8_+_30690195 0.41 ENSDART00000005345
ureidopropionase, beta
chr9_-_48152388 0.41

chr9_-_470390 0.40 ENSDART00000162054
si:dkey-11f4.16
chr18_-_47026460 0.40 ENSDART00000108574
GRAM domain containing 1Bb
chr1_+_14539766 0.39 ENSDART00000109911
heparan-alpha-glucosaminide N-acetyltransferase
chr20_+_5063644 0.39 ENSDART00000081351
ENSDART00000131103
ENSDART00000028039
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1
chr18_+_18465885 0.36 ENSDART00000165079
siah E3 ubiquitin protein ligase 1
chr7_-_73620490 0.36 ENSDART00000158891
ENSDART00000111622
ENSDARG00000079652
chr8_+_47108500 0.36 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr3_+_24059652 0.36 ENSDART00000034762
proline rich 15-like a
chr2_+_3702282 0.35 ENSDART00000133007
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr23_-_45074750 0.35 ENSDART00000148669
si:ch73-269m23.5
chr15_-_29420984 0.35 ENSDART00000127795
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr5_+_29327447 0.34

chr15_-_16140187 0.34 ENSDART00000080413
serine/arginine-rich splicing factor 1a
chr22_+_16293724 0.33 ENSDART00000164161
oxysterol binding protein-like 1A
chr15_+_21399299 0.33 ENSDART00000154914
ENSDARG00000097950
chr2_-_5816954 0.33 ENSDART00000014020
somatostatin 2
chr3_-_49104540 0.31 ENSDART00000138503
bloodthirsty-related gene family, member 2
chr1_-_45972732 0.30 ENSDART00000134450
emopamil binding protein-like
chr13_-_30938325 0.30 ENSDART00000112653
WDFY family member 4
chr23_-_24562107 0.30 ENSDART00000155593
transmembrane protein 82
chr24_-_32235674 0.29 ENSDART00000166212
cubilin (intrinsic factor-cobalamin receptor)
chr8_-_214434 0.29 ENSDART00000168412
hydroxysteroid (17-beta) dehydrogenase 4
chr4_-_16461881 0.29 ENSDART00000128835
wu:fc23c09
chr6_-_40431708 0.29 ENSDART00000156005
si:dkey-28n18.9
chr12_+_29994657 0.28 ENSDART00000042572
ENSDART00000153025
actin binding LIM protein 1b
chr15_-_1225639 0.27

chr10_+_22004006 0.27

chr24_+_36022833 0.26 ENSDART00000088480
ATP-binding cassette, sub-family D (ALD), member 4
chr5_+_43365449 0.25 ENSDART00000113502
si:dkey-84j12.1
chr23_+_17946933 0.25 ENSDART00000117743
Small nucleolar RNA SNORD59
chr15_+_21808902 0.24 ENSDART00000016860
protein phosphatase 2, regulatory subunit A, beta b
chr12_+_49091872 0.23 ENSDART00000178771
ENSDARG00000107503
chr15_+_21399228 0.22 ENSDART00000154914
ENSDARG00000097950
chr3_-_23513293 0.21 ENSDART00000140264
even-skipped-like1
chr9_+_21572750 0.20 ENSDART00000130023
crystallin, lambda 1
chr17_-_17928974 0.19 ENSDART00000090447
HHIP-like 1
chr23_-_9928561 0.19

chr7_-_30009715 0.19 ENSDART00000173989
small EDRK-rich factor 2
chr23_-_43703447 0.18 ENSDART00000170500
itchy E3 ubiquitin protein ligase b
chr13_-_37002066 0.17 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr14_+_6122644 0.17 ENSDART00000149783
ENSDART00000148461
ATP-binding cassette, sub-family A (ABC1), member 1B
chr20_-_36906124 0.16 ENSDART00000166966
solute carrier family 25, member 27
chr3_+_23536083 0.16

chr8_+_39768702 0.14 ENSDART00000018862
HNF1 homeobox a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
0.6 1.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.5 1.5 GO:1903793 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.5 3.9 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.5 2.8 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.4 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.4 3.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 3.2 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.4 3.9 GO:0033292 T-tubule organization(GO:0033292)
0.4 1.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.3 2.0 GO:0033700 phospholipid efflux(GO:0033700)
0.3 1.6 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.3 1.6 GO:0071398 cellular response to fatty acid(GO:0071398)
0.2 1.0 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.2 1.0 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.2 1.1 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2 0.7 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 0.6 GO:0032475 otolith formation(GO:0032475)
0.2 4.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 2.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.6 GO:0008347 glial cell migration(GO:0008347)
0.2 1.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.7 GO:1990544 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.2 2.9 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.2 0.7 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.2 1.7 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.4 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 6.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 2.7 GO:0051014 actin filament severing(GO:0051014)
0.1 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431) chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.7 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 2.9 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:0098921 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.5 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.5 GO:0032543 mitochondrial translation(GO:0032543)
0.1 9.0 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 1.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.7 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 2.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.8 GO:0030073 insulin secretion(GO:0030073)
0.0 1.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.7 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 3.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.9 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0072019 proximal convoluted tubule development(GO:0072019)
0.0 0.5 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 0.2 GO:0009409 response to cold(GO:0009409)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.6 GO:0031430 M band(GO:0031430)
0.1 3.1 GO:0045095 keratin filament(GO:0045095)
0.1 3.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 2.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.9 GO:0043209 myelin sheath(GO:0043209)
0.1 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.8 GO:0005882 intermediate filament(GO:0005882)
0.1 2.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 3.4 GO:0043235 receptor complex(GO:0043235)
0.0 14.0 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.7 2.8 GO:0030151 molybdenum ion binding(GO:0030151)
0.5 2.7 GO:0034632 retinol transporter activity(GO:0034632)
0.5 1.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.4 3.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 0.9 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.3 1.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.7 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 3.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.5 GO:0004691 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.7 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.2 1.5 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 2.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 2.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.6 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 3.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 4.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 3.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 6.5 GO:0051015 actin filament binding(GO:0051015)
0.0 9.1 GO:0008289 lipid binding(GO:0008289)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)
0.0 1.9 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 1.7 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.0 PID FGF PATHWAY FGF signaling pathway
0.1 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 2.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 1.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 0.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.6 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 3.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.