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Results for homeza

Z-value: 1.32

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Transcription factors associated with homeza

Gene Symbol Gene ID Gene Info
ENSDARG00000054304 homeobox and leucine zipper encoding a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
homezadr10_dc_chr2_+_38288916_382891650.611.3e-02Click!

Activity profile of homeza motif

Sorted Z-values of homeza motif

Network of associatons between targets according to the STRING database.

First level regulatory network of homeza

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_34971985 3.49 ENSDART00000141201
cyclin A1
chr6_-_8125341 3.18 ENSDART00000139161
ENSDART00000140021
acid phosphatase 5a, tartrate resistant
chr21_-_13593659 3.01 ENSDART00000065817
POU domain, class 5, transcription factor 3
chr21_+_20360180 2.78 ENSDART00000003299
ENSDARG00000025174
chr15_-_20904022 2.59 ENSDART00000141746
aldehyde dehydrogenase 3 family, member A2a
chr1_-_51576354 2.48 ENSDART00000083946
phospholipase D family, member 6
chr19_-_868378 2.38

chr6_-_43297126 2.36 ENSDART00000154170
FERM domain containing 4Ba
chr9_-_51745361 2.22 ENSDART00000154959
ENSDARG00000097096
chr7_+_17848688 2.18 ENSDART00000055810
zRAB1B, member RAS oncogene family a
chr16_+_27680365 2.16 ENSDART00000005625
GLI pathogenesis-related 2, like
chr10_-_25246786 2.08 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr8_-_23759076 2.01 ENSDART00000145894
zgc:195245
chr7_+_15479700 2.01

chr22_-_5600910 1.97 ENSDART00000179579
ENSDARG00000106226
chr3_-_20833004 1.94 ENSDART00000160794
solute carrier family 35, member B1
chr25_+_5845303 1.92 ENSDART00000163948
ENSDARG00000053246
chr16_+_53391438 1.86 ENSDART00000010792
phosphatidylserine synthase 1a
chr20_-_23527234 1.83 ENSDART00000004625
zygote arrest 1
chr24_+_34183462 1.82 ENSDART00000143995
zgc:92591
chr5_+_40896478 1.79 ENSDART00000039369
Fanconi anemia, complementation group G
chr2_-_601945 1.78

chr11_-_25019899 1.77 ENSDART00000123567
snail family zinc finger 1a
chr19_+_39689450 1.74

chr2_+_27730940 1.74 ENSDART00000134976
si:ch73-382f3.1
chr2_-_57339717 1.71 ENSDART00000150034
protein inhibitor of activated STAT, 4b
chr5_+_69013399 1.67 ENSDART00000162057
ENSDART00000166893
SET domain containing (lysine methyltransferase) 8b
chr9_-_46614763 1.65 ENSDART00000009790
connexin 43.4
chr10_+_14984467 1.64

chr16_-_33047066 1.61 ENSDART00000147941
ENSDART00000075218
malic enzyme 1, NADP(+)-dependent, cytosolic
chr10_-_34971926 1.58 ENSDART00000141201
cyclin A1
chr15_+_44168257 1.57 ENSDART00000176254
ENSDARG00000106724
chr2_+_11423028 1.57 ENSDART00000144982
LIM homeobox 8a
chr6_-_12787256 1.54 ENSDART00000157139
transmembrane BAX inhibitor motif containing 1a
chr11_-_40383013 1.54 ENSDART00000112140
family with sequence similarity 213, member B
chr10_-_44634139 1.49 ENSDART00000010056
ENSDART00000169919
coiled-coil domain containing 62
chr6_-_12786937 1.48 ENSDART00000157139
transmembrane BAX inhibitor motif containing 1a
chr15_-_20903444 1.47 ENSDART00000139551
aldehyde dehydrogenase 3 family, member A2a
chr24_+_34183557 1.46 ENSDART00000143995
zgc:92591
KN150226v1_+_11535 1.46

chr3_-_20832951 1.40 ENSDART00000160794
solute carrier family 35, member B1
chr19_+_8693855 1.38 ENSDART00000144925
sorting nexin family member 27a
chr15_-_970988 1.36 ENSDART00000106627
ENSDART00000102239
zgc:162936
chr3_+_16692138 1.35 ENSDART00000023985
zgc:153952
chr10_+_16078433 1.35 ENSDART00000065037
ENSDART00000124502
lamin B1
chr3_-_32231069 1.34 ENSDART00000035545
protein arginine methyltransferase 1
chr10_-_44634167 1.34 ENSDART00000010056
ENSDART00000169919
coiled-coil domain containing 62
chr8_+_41004169 1.33

chr8_+_40463218 1.33

chr24_+_39237314 1.32 ENSDART00000155346
TBC1 domain family, member 24
chr15_-_20904050 1.32 ENSDART00000141746
aldehyde dehydrogenase 3 family, member A2a
chr3_+_30187036 1.31 ENSDART00000151006
ENSDARG00000096295
chr10_+_16078021 1.31 ENSDART00000065037
ENSDART00000124502
lamin B1
chr24_+_23571714 1.28 ENSDART00000080332
COP9 signalosome subunit 5
chr15_+_24741620 1.27 ENSDART00000078014
polymerase (DNA-directed), delta interacting protein 2
chr5_+_40896320 1.27 ENSDART00000039369
Fanconi anemia, complementation group G
chr21_+_20360748 1.27 ENSDART00000146615
ENSDARG00000025174
chr8_-_22493608 1.26 ENSDART00000021514
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr8_-_11806733 1.26 ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr18_-_35432838 1.25 ENSDART00000141703
small nuclear ribonucleoprotein polypeptide A
chr8_-_29842489 1.24 ENSDART00000149297
solute carrier family 20 (phosphate transporter), member 2
chr6_-_8125287 1.24 ENSDART00000139161
ENSDART00000140021
acid phosphatase 5a, tartrate resistant
chr6_-_6818607 1.24 ENSDART00000151822
tubulin, alpha 8 like 4
chr3_-_19913207 1.23

chr15_+_24628191 1.22 ENSDART00000140658
dehydrogenase/reductase (SDR family) member 13b
chr17_+_28594742 1.22 ENSDART00000062430
ENSDART00000113300
MIS18 binding protein 1
chr5_-_31257158 1.22 ENSDART00000112546
protein kinase N3
chr25_+_20596490 1.20 ENSDART00000073648
KxDL motif containing 1
chr3_-_39117855 1.20 ENSDART00000102678
N-myristoyltransferase 1a
chr18_-_43890836 1.19 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr17_+_16184621 1.17 ENSDART00000156832
kinesin family member 13Ba
chr4_+_13902603 1.17 ENSDART00000137549
periphilin 1
chr16_-_12582192 1.17

chr17_-_24860924 1.15 ENSDART00000123147
zinc finger and BTB domain containing 8A
chr13_+_3807780 1.14 ENSDART00000012759
Yip1 domain family, member 3
chr8_-_11806698 1.14 ENSDART00000064017
Rap guanine nucleotide exchange factor (GEF) 1a
chr16_+_53632289 1.13 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr1_-_29958364 1.13 ENSDART00000085454
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
chr18_-_35432655 1.13 ENSDART00000137663
small nuclear ribonucleoprotein polypeptide A
chr23_+_27777325 1.11 ENSDART00000134008
limb development membrane protein 1-like
chr4_+_9010972 1.11 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr5_+_29996321 1.11 ENSDART00000124487
histone H4 transcription factor
chr14_-_30196413 1.09 ENSDART00000178574
ENSDARG00000106816
chr19_-_31988686 1.09 ENSDART00000161739
tyrosyl-DNA phosphodiesterase 2b
chr24_-_21224371 1.08 ENSDART00000156537
spindle and centriole associated protein 1
chr2_-_19705537 1.07 ENSDART00000168627
zinc finger, FYVE domain containing 9a
chr23_+_35327654 1.07 ENSDART00000165034
si:ch211-225h24.2
chr3_+_18287783 1.07 ENSDART00000144690
TBC1 domain family, member 16
chr7_+_39812522 1.06 ENSDART00000099046
ENSDARG00000036489
chr18_+_22426900 1.05 ENSDART00000115388
craniofacial development protein 1
chr7_+_22524917 1.04 ENSDART00000112169
RNA binding motif protein 4.2
chr15_-_20903489 1.03 ENSDART00000139551
aldehyde dehydrogenase 3 family, member A2a
KN150226v1_+_11474 1.03

chr24_+_35296732 1.03 ENSDART00000172652
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr15_+_46053808 1.03

chr1_-_25970424 1.02 ENSDART00000152401
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr21_-_43654780 1.01 ENSDART00000142733
si:dkey-229d11.5
chr18_-_12358605 1.01 ENSDART00000114024
family with sequence similarity 107, member B
chr1_-_25369230 1.00 ENSDART00000171752
programmed cell death 4a
chr23_+_6652454 0.99 ENSDART00000081763
RNA binding motif protein 38
chr13_-_44885278 0.99 ENSDART00000159021
KH domain containing, RNA binding, signal transduction associated 1a
chr7_+_39812659 0.99 ENSDART00000099046
ENSDARG00000036489
chr1_-_51075777 0.99 ENSDART00000152745
small nuclear ribonucleoprotein polypeptide B2
chr7_-_64745132 0.98 ENSDART00000112166
family with sequence similarity 60, member A, like
chr24_+_28304276 0.98 ENSDART00000018095
SH3-domain GRB2-like endophilin B1a
chr8_-_39788989 0.98 ENSDART00000067843
zgc:162025
chr20_-_49067167 0.98 ENSDART00000163071
ENSDART00000170617
5'-3' exoribonuclease 2
chr23_+_33981443 0.97 ENSDART00000159445
citrate synthase
chr11_+_19440815 0.97 ENSDART00000005639
THO complex 7
chr19_+_7082199 0.97 ENSDART00000110366
zinc finger and BTB domain containing 22b
chr12_+_6197452 0.97

chr12_-_4800362 0.96 ENSDART00000172093
si:ch211-93e11.8
chr15_+_17350036 0.96 ENSDART00000134512
clathrin, heavy chain b (Hc)
chr21_+_11686037 0.95 ENSDART00000031786
glutaredoxin (thioltransferase)
chr20_+_1364879 0.95 ENSDART00000145981
ENSDART00000152709
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr8_-_16689736 0.95 ENSDART00000049676
DEP domain containing 1a
chr11_+_14285767 0.95 ENSDART00000171347
si:ch211-262i1.6
chr3_+_18287645 0.94 ENSDART00000136243
TBC1 domain family, member 16
chr4_+_29008199 0.94 ENSDART00000150629
si:dkey-23a23.3
chr24_-_21224397 0.94 ENSDART00000156537
spindle and centriole associated protein 1
chr9_+_8990774 0.94 ENSDART00000133899
ubiquitin conjugating enzyme E2 A, like
chr1_+_40894908 0.91 ENSDART00000111367
si:dkey-56e3.3
chr7_+_66410533 0.91 ENSDART00000027616
ENSDART00000162763
eukaryotic translation initiation factor 4, gamma 2a
chr14_-_23980060 0.91 ENSDART00000054243
D4, zinc and double PHD fingers family 2, like
chr15_+_24741931 0.91 ENSDART00000143137
polymerase (DNA-directed), delta interacting protein 2
chr14_+_14850200 0.91 ENSDART00000167966
zgc:158852
chr3_+_30962827 0.91 ENSDART00000153074
si:dkey-66i24.9
chr18_-_6896957 0.91 ENSDART00000175747
protein phosphatase 6, regulatory subunit 2b
chr16_+_29090602 0.91 ENSDART00000149454
G patch domain containing 4
chr16_-_29470341 0.90 ENSDART00000149289
toll-like receptor 18
chr19_+_42758938 0.90 ENSDART00000077059
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr25_+_20596613 0.90 ENSDART00000073648
KxDL motif containing 1
chr15_-_20903583 0.90 ENSDART00000031625
aldehyde dehydrogenase 3 family, member A2a
chr22_+_17474904 0.90 ENSDART00000061366
RAB11B, member RAS oncogene family, a
chr20_+_40590886 0.89

chr9_-_41238226 0.89 ENSDART00000008275
adenosine deaminase, tRNA-specific 3
chr20_+_6545449 0.88 ENSDART00000145763
si:ch211-191a24.4
chr23_-_31323662 0.88

chr25_-_15176295 0.87

KN150712v1_-_26150 0.87

chr24_+_23571827 0.87 ENSDART00000080332
COP9 signalosome subunit 5
KN150034v1_+_1223 0.86

chr7_+_39812732 0.86 ENSDART00000099046
ENSDARG00000036489
chr9_+_44921195 0.86 ENSDART00000145271
NCK-associated protein 1
chr19_-_17400440 0.86 ENSDART00000160433
splicing factor 3a, subunit 3
chr9_-_20743808 0.86

chr13_-_36486255 0.85 ENSDART00000160250
ENSDARG00000103360
chr8_-_16479425 0.85 ENSDART00000146469
ENSDART00000132681
tetratricopeptide repeat domain 39A
chr10_-_36849596 0.85

chr8_-_20882626 0.85 ENSDART00000025356
HAUS augmin-like complex, subunit 5
chr21_-_11106675 0.84 ENSDART00000167666
DnaJ (Hsp40) homolog, subfamily C, member 21
chr17_+_23534953 0.84 ENSDART00000135814
pantothenate kinase 1a
chr13_+_3808095 0.84 ENSDART00000012759
Yip1 domain family, member 3
chr17_-_15487267 0.84

chr3_+_30962542 0.83 ENSDART00000153074
si:dkey-66i24.9
chr19_+_7708513 0.83 ENSDART00000129994
ENSDART00000131324
ENSDART00000104731
pygopus homolog 2 (Drosophila)
chr10_-_15382145 0.82 ENSDART00000133919
pumilio RNA-binding family member 3
chr7_-_18460264 0.82 ENSDART00000173905
tRNA methyltransferase 10A
chr19_-_4206143 0.82 ENSDART00000164611
Ras-related GTP binding Cb
chr9_+_8990576 0.82 ENSDART00000133899
ubiquitin conjugating enzyme E2 A, like
chr5_+_37497397 0.82

chr9_-_10174409 0.81 ENSDART00000004745
histamine N-methyltransferase
chr9_-_25370812 0.81 ENSDART00000012582
esterase D/formylglutathione hydrolase
chr6_-_52677363 0.81 ENSDART00000083830
syndecan 4
chr17_+_13292569 0.79 ENSDART00000177104
ENSDARG00000108498
chr16_-_31494275 0.79 ENSDART00000056551
casein kinase 2, alpha 1 polypeptide
chr25_-_31979408 0.78

chr1_-_25970563 0.78 ENSDART00000152401
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr10_-_36849734 0.78

chr22_-_6916274 0.78

chr9_-_34700736 0.77 ENSDART00000169114
protein phosphatase 2, regulatory subunit B'', beta
chr3_+_40147509 0.77 ENSDART00000017304
cleavage and polyadenylation specific factor 4
chr23_-_41367783 0.77

chr22_-_24957034 0.77 ENSDART00000142147
dynein, axonemal, light chain 4b
chr3_+_52699683 0.77 ENSDART00000125136
DSN1 homolog, MIS12 kinetochore complex component
chr3_+_19490148 0.76

chr21_-_21604542 0.75 ENSDART00000010282
carbonyl reductase 1-like
chr25_-_12316228 0.75 ENSDART00000168275
de-etiolated homolog 1 (Arabidopsis)
chr22_-_9809500 0.75

chr3_+_22914688 0.74 ENSDART00000156472
beta-1,4-N-acetyl-galactosaminyl transferase 2, tandem duplicate 2
chr7_+_28341426 0.74 ENSDART00000019991
solute carrier family 7, member 6 opposite strand
chr11_+_37385705 0.74 ENSDART00000129918
kinesin family member 17
chr9_+_55429357 0.74

chr20_+_44600015 0.74 ENSDART00000023763
WD repeat and coiled coil containing
chr19_+_8693695 0.74 ENSDART00000144925
sorting nexin family member 27a
chr19_-_27755498 0.74 ENSDART00000137346
zinc ribbon domain containing 1
chr15_+_20303673 0.73 ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr8_-_44247277 0.73

chr12_-_308764 0.73 ENSDART00000066579
ENSDART00000171396
6-pyruvoyltetrahydropterin synthase
chr8_-_8451037 0.73 ENSDART00000064113
activator of basal transcription 1
chr16_+_53632152 0.71 ENSDART00000124691
sphingomyelin phosphodiesterase 5
chr3_+_35292809 0.71 ENSDART00000176673
ENSDARG00000108159
chr9_+_32838316 0.71 ENSDART00000172033
RAB, member of RAS oncogene family-like 3
chr6_-_24292584 0.71 ENSDART00000163965
bromodomain, testis-specific
chr12_-_31346300 0.71 ENSDART00000175929
acyl-CoA synthetase long-chain family member 5
chr14_-_32319519 0.71

chr7_-_51474798 0.71 ENSDART00000175523
histone deacetylase 8
chr3_-_26112995 0.71 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr1_-_25369054 0.70 ENSDART00000171752
programmed cell death 4a
chr16_+_54953101 0.70

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.6 4.4 GO:0045453 bone resorption(GO:0045453)
0.5 1.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.5 1.4 GO:1902001 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.4 3.0 GO:0000338 protein deneddylation(GO:0000338)
0.4 1.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.3 2.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 1.4 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.3 3.0 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.3 2.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.3 1.3 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.3 1.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.3 1.2 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.3 1.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 0.8 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.3 1.9 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.3 0.8 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2 2.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.7 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) RNA 5'-end processing(GO:0000966) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.7 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 1.7 GO:0032196 transposition(GO:0032196)
0.2 0.6 GO:0071887 leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
0.2 1.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 0.7 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746) regulation of protein lipidation(GO:1903059)
0.2 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.5 GO:0021861 forebrain radial glial cell differentiation(GO:0021861)
0.2 2.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.2 0.8 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.1 1.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.7 GO:0007141 male meiosis I(GO:0007141)
0.1 2.1 GO:0032418 lysosome localization(GO:0032418)
0.1 1.0 GO:0097065 anterior head development(GO:0097065)
0.1 1.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 7.1 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 0.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.8 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 1.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.4 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1 0.3 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 2.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.1 0.2 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.1 0.5 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.7 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 0.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 5.1 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.8 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.6 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.5 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 2.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.7 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 1.5 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.8 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 1.8 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.6 GO:0035065 regulation of histone acetylation(GO:0035065)
0.1 0.3 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.2 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.1 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.9 GO:0043486 histone exchange(GO:0043486)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.0 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0043111 replication fork arrest(GO:0043111)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 1.3 GO:0006284 base-excision repair(GO:0006284)
0.0 1.0 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.7 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 1.1 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.0 GO:0030282 bone mineralization(GO:0030282)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0034727 lysosomal microautophagy(GO:0016237) pexophagy(GO:0030242) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.8 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.4 GO:0016233 telomere capping(GO:0016233)
0.0 0.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0051645 Golgi localization(GO:0051645)
0.0 0.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 1.3 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.1 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.1 GO:0065001 specification of organ axis polarity(GO:0010084) specification of axis polarity(GO:0065001)
0.0 1.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.5 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0 0.6 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 6.5 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.0 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.0 0.5 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.6 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 1.1 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 1.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.5 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.0 0.3 GO:0009408 response to heat(GO:0009408)
0.0 1.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0061136 regulation of proteasomal protein catabolic process(GO:0061136)
0.0 0.8 GO:0006413 translational initiation(GO:0006413)
0.0 0.6 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.1 GO:0006596 polyamine biosynthetic process(GO:0006596)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.3 3.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 2.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 2.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 0.8 GO:0000941 nuclear MIS12/MIND complex(GO:0000818) condensed nuclear chromosome inner kinetochore(GO:0000941)
0.3 1.8 GO:0033503 HULC complex(GO:0033503)
0.2 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 2.0 GO:0008180 COP9 signalosome(GO:0008180)
0.2 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 3.4 GO:0005685 U1 snRNP(GO:0005685)
0.2 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.2 2.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 1.0 GO:0032797 SMN complex(GO:0032797)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 0.8 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.6 GO:0000811 GINS complex(GO:0000811)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.6 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.9 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.9 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 5.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:0070187 telosome(GO:0070187)
0.1 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 3.3 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0031968 outer membrane(GO:0019867) organelle outer membrane(GO:0031968)
0.0 0.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 1.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 3.3 GO:0005769 early endosome(GO:0005769)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686) preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 1.3 GO:0005925 focal adhesion(GO:0005925)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 1.4 GO:0044815 nucleosome(GO:0000786) DNA packaging complex(GO:0044815)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0035755 cardiolipin hydrolase activity(GO:0035755)
0.8 7.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6 2.5 GO:0005460 UDP-glucose transmembrane transporter activity(GO:0005460)
0.6 4.8 GO:0008199 ferric iron binding(GO:0008199)
0.5 1.6 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.5 1.8 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.4 1.3 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.4 1.7 GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.4 1.3 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.4 3.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 3.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.3 1.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 1.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.2 1.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.6 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.2 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.8 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 0.5 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.2 1.4 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.7 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 1.9 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.2 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.7 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 1.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 1.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 2.1 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.6 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 1.8 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.6 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 0.4 GO:0030882 antigen binding(GO:0003823) lipid antigen binding(GO:0030882)
0.1 0.3 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 1.7 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.9 GO:0030332 cyclin binding(GO:0030332)
0.1 5.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:0061133 peptidase activator activity(GO:0016504) endopeptidase activator activity(GO:0061133)
0.1 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 1.0 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 1.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 6.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 4.3 GO:0042393 histone binding(GO:0042393)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 2.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.3 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 1.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 1.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.6 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex