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Results for hoxa1a+hoxb1b+hoxc1a

Z-value: 1.66

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Transcription factors associated with hoxa1a+hoxb1b+hoxc1a

Gene Symbol Gene ID Gene Info
hoxb1b
ENSDARG00000054033 homeobox B1b
hoxc1a
ENSDARG00000070337 homeobox C1a
hoxa1a
ENSDARG00000104307 homeobox A1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc1adr10_dc_chr23_+_36079624_360796790.985.5e-12Click!
hoxa1adr10_dc_chr19_+_20213125_202131500.917.7e-07Click!
hoxb1bdr10_dc_chr12_+_27050043_270500920.721.5e-03Click!

Activity profile of hoxa1a+hoxb1b+hoxc1a motif

Sorted Z-values of hoxa1a+hoxb1b+hoxc1a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa1a+hoxb1b+hoxc1a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_+_24932972 7.91 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr3_-_54893038 6.26 ENSDART00000155871
ENSDART00000109016
hbae3
hemoglobin alpha embryonic-3
chr17_+_17841882 6.00 ENSDART00000123311
ism2a
isthmin 2a
chr5_-_65349550 5.26 ENSDART00000164228
nrarpb
notch-regulated ankyrin repeat protein b
chr20_-_9474672 5.24 ENSDART00000152674
ENSDARG00000033201
ENSDARG00000033201
chr6_+_60190849 5.12

chr24_+_389982 4.89 ENSDART00000061973
tgfbr1b
transforming growth factor, beta receptor 1 b
chr21_-_43083936 4.70 ENSDART00000040169
jakmip2
janus kinase and microtubule interacting protein 2
chr5_+_16669696 4.54

chr12_-_25825072 4.40

chr20_-_32543497 4.22 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr6_+_29800606 4.13 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr19_-_2399429 4.06 ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr20_-_29580624 4.05 ENSDART00000062370
actc1a
actin, alpha, cardiac muscle 1a
chr25_+_20118286 3.73 ENSDART00000104297
tnnt2d
troponin T2d, cardiac
chr19_-_47994946 3.43 ENSDART00000114549
CU695215.1
ENSDARG00000076126
chr7_+_16610457 3.32

chr21_-_26459113 3.28 ENSDART00000157255
cd248b
CD248 molecule, endosialin b
chr7_+_16583234 3.24 ENSDART00000173580
nav2a
neuron navigator 2a
chr8_-_40425193 3.12 ENSDART00000130798
myl7
myosin, light chain 7, regulatory
chr14_+_503643 3.11

chr23_+_2391223 3.02

chr23_-_12079877 2.96 ENSDART00000147956
ENSDARG00000076364
ENSDARG00000076364
chr3_-_45779817 2.84 ENSDART00000164361
gcgra
glucagon receptor a
chr11_+_43559400 2.81

chr17_-_52020689 2.80 ENSDART00000019766
tgfb3
transforming growth factor, beta 3
chr6_+_30441419 2.64

chr18_-_23889256 2.63 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr7_+_21521123 2.63 ENSDART00000112531
ENSDART00000100936
tmem88b
transmembrane protein 88 b
chr18_+_24935499 2.52

chr21_+_16987306 2.49 ENSDART00000080628
arpc3
actin related protein 2/3 complex, subunit 3
chr20_-_35938683 2.41 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr16_+_46435014 2.41 ENSDART00000144000
rpz2
rapunzel 2
chr16_+_14817799 2.38 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr3_-_44113070 2.37 ENSDART00000160717
znf750
zinc finger protein 750
chr23_+_36079164 2.36 ENSDART00000103131
hoxc1a
homeo box C1a
chr5_+_19802818 2.31

chr23_+_36079624 2.19 ENSDART00000103131
hoxc1a
homeo box C1a
chr3_+_23638277 2.19 ENSDART00000110682
hoxb1a
homeobox B1a
chr24_+_40974634 2.16

chr16_+_10531986 2.12 ENSDART00000161568
ino80e
INO80 complex subunit E
chr3_+_15656123 2.03 ENSDART00000055834
phospho1
phosphatase, orphan 1
chr7_+_42124857 2.02 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr16_+_46902372 1.99 ENSDART00000177679
thsd7ab
thrombospondin, type I, domain containing 7Ab
chr1_+_45503061 1.96 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr17_-_6915458 1.90 ENSDART00000081797
sash1b
SAM and SH3 domain containing 1b
chr9_+_32267615 1.85

chr11_+_34562255 1.84 ENSDART00000103157
slc38a3a
solute carrier family 38, member 3a
chr17_+_22936598 1.78 ENSDART00000155145
ltbp1
latent transforming growth factor beta binding protein 1
chr24_-_26744092 1.77 ENSDART00000087991
fndc3bb
fibronectin type III domain containing 3Bb
chr4_-_14927871 1.73 ENSDART00000110199
prdm4
PR domain containing 4
chr8_-_17692185 1.72

chr18_-_23889025 1.70 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr10_+_17494274 1.68

chr1_+_23093114 1.65

chr18_-_23888988 1.62 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr17_-_26586506 1.61 ENSDART00000087062
fam149b1
family with sequence similarity 149, member B1
chr20_+_27792255 1.60 ENSDART00000153299
si:dkey-1h6.8
si:dkey-1h6.8
chr21_-_14534576 1.59 ENSDART00000089967
ENSDART00000132142
cacna1bb
calcium channel, voltage-dependent, N type, alpha 1B subunit, b
chr5_-_71295651 1.58

chr9_-_23406315 1.57 ENSDART00000159256
kif5c
kinesin family member 5C
chr7_+_73466424 1.55 ENSDART00000123429
si:dkey-46i9.6
si:dkey-46i9.6
chr4_-_1564624 1.53 ENSDART00000168633
BICD1 (1 of many)
BICD cargo adaptor 1
chr16_-_16796313 1.50

chr23_-_2027166 1.49 ENSDART00000127443
prdm5
PR domain containing 5
chr16_+_21121428 1.49

chr23_-_19053587 1.45

chr13_+_35619748 1.43 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr5_+_6054781 1.43 ENSDART00000060532
zgc:110796
zgc:110796
chr11_-_11487856 1.42 ENSDART00000030103
krt94
keratin 94
chr14_+_23917724 1.42 ENSDART00000138082
ENSDART00000079215
stc2a
stanniocalcin 2a
chr22_-_15576473 1.39 ENSDART00000036075
tpm4a
tropomyosin 4a
chr18_-_23889169 1.33 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr14_+_34207218 1.33 ENSDART00000135608
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr22_-_34961734 1.22 ENSDART00000165142
slit1b
slit homolog 1b (Drosophila)
chr7_-_71929355 1.16

chr10_-_27780050 1.15 ENSDART00000138149
si:dkey-33o22.1
si:dkey-33o22.1
chr24_+_27469268 1.15 ENSDART00000105774
ek1
eph-like kinase 1
chr3_-_55399331 1.14 ENSDART00000162413
axin2
axin 2 (conductin, axil)
chr20_+_22780756 1.11

chr18_+_5707066 1.09

chr22_-_562269 1.03 ENSDART00000086434
tmcc2
transmembrane and coiled-coil domain family 2
chr14_-_46645127 1.01

chr17_-_19606453 0.99 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr1_-_25225339 0.99 ENSDART00000109714
usp53b
ubiquitin specific peptidase 53b
chr1_+_19376127 0.97 ENSDART00000088653
prss12
protease, serine, 12 (neurotrypsin, motopsin)
chr17_-_8016214 0.96 ENSDART00000148520
syne1b
spectrin repeat containing, nuclear envelope 1b
chr9_+_32267297 0.95

chr21_+_10699071 0.93

chr5_-_51631013 0.92 ENSDART00000010757
rgmb
repulsive guidance molecule family member b
chr1_-_20132900 0.90 ENSDART00000054472
tll1
tolloid-like 1
chr14_-_26078923 0.90 ENSDART00000022236
emx3
empty spiracles homeobox 3
chr4_-_5643440 0.89 ENSDART00000010903
rsph9
radial spoke head 9 homolog
chr3_-_60723276 0.84

chr7_+_30803603 0.81 ENSDART00000173805
tjp1a
tight junction protein 1a
chr10_+_20151165 0.76 ENSDART00000142708
dmtn
dematin actin binding protein
chr20_-_32543458 0.75 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr1_+_23093475 0.73

chr16_-_31230568 0.73 ENSDART00000058829
scrt1b
scratch family zinc finger 1b
chr2_-_16548451 0.73 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr3_-_40387858 0.72 ENSDART00000055194
actb2
actin, beta 2
chr4_-_70713033 0.72 ENSDART00000169130
ftr64
finTRIM family, member 64
chr14_+_43599635 0.71 ENSDART00000155539
CR786577.1
ENSDARG00000097875
chr7_+_29681510 0.69 ENSDART00000173737
tpma
alpha-tropomyosin
chr24_+_34227202 0.69 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr7_+_16583304 0.67 ENSDART00000113332
nav2a
neuron navigator 2a
chr18_+_41552295 0.67 ENSDART00000087445
tsen34
TSEN34 tRNA splicing endonuclease subunit
chr22_+_35113233 0.66 ENSDART00000123066
srfa
serum response factor a
chr21_-_28304276 0.66 ENSDART00000141629
nrxn2a
neurexin 2a
chr3_+_23621561 0.65 ENSDART00000146636
hoxb2a
homeobox B2a
chr21_-_36886505 0.65 ENSDART00000113678
wwc1
WW and C2 domain containing 1
chr7_-_46510731 0.64

chr13_-_43027245 0.62 ENSDART00000099601
ENSDARG00000068784
ENSDARG00000068784
chr21_+_10698503 0.61 ENSDART00000144460
znf532
zinc finger protein 532
chr17_-_44895892 0.58 ENSDART00000123971
fam161b
family with sequence similarity 161, member B
chr20_+_29685096 0.57 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr5_+_60457842 0.54

chr23_+_2391317 0.53

chr12_+_16848206 0.49

chr5_-_71277652 0.48

chr14_+_4169371 0.45 ENSDART00000136665
gnpda2
glucosamine-6-phosphate deaminase 2
chr3_+_60724858 0.45 ENSDART00000044096
helz
helicase with zinc finger
chr25_+_7287952 0.44 ENSDART00000170569
syt12
synaptotagmin XII
chr5_+_8460247 0.42 ENSDART00000091397
tnksb
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b
chr17_-_44895849 0.41 ENSDART00000123971
fam161b
family with sequence similarity 161, member B
chr16_-_29502678 0.41 ENSDART00000148405
si:ch211-113g11.6
si:ch211-113g11.6
chr17_+_44896297 0.37 ENSDART00000133103
coq6
coenzyme Q6 monooxygenase
chr20_-_53264360 0.37 ENSDART00000124231
ENSDARG00000090191
ENSDARG00000090191
chr4_-_13256905 0.34 ENSDART00000026593
ENSDART00000150577
grip1
glutamate receptor interacting protein 1
chr15_+_32139366 0.33 ENSDART00000153791
dchs1a
dachsous cadherin-related 1a
chr9_+_32262914 0.33 ENSDART00000110204
pikfyve
phosphoinositide kinase, FYVE finger containing
chr10_+_20151082 0.32 ENSDART00000142708
dmtn
dematin actin binding protein
KN150266v1_-_69477 0.32

chr14_+_18956828 0.32 ENSDART00000005738
slitrk2
SLIT and NTRK-like family, member 2
chr4_-_12107094 0.28 ENSDART00000048675
mrps33
mitochondrial ribosomal protein S33
chr8_+_18800414 0.27 ENSDART00000160732
mpnd
MPN domain containing
chr17_+_51675406 0.23 ENSDART00000157171
si:ch211-168d23.3
si:ch211-168d23.3
chr7_+_13130332 0.23 ENSDART00000166318
dagla
diacylglycerol lipase, alpha
chr22_-_15576405 0.22 ENSDART00000009054
tpm4a
tropomyosin 4a
chr23_-_16765933 0.21 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr22_+_11827925 0.21 ENSDART00000179540
mras
muscle RAS oncogene homolog
chr21_-_28304413 0.18 ENSDART00000141629
nrxn2a
neurexin 2a
chr17_+_44896084 0.17 ENSDART00000085009
coq6
coenzyme Q6 monooxygenase
chr2_-_14833381 0.14

chr12_-_30898994 0.13

chr22_+_1121048 0.12 ENSDART00000158017
ENSDARG00000100747
ENSDARG00000100747
chr6_-_31589470 0.08 ENSDART00000111837
raver2
ribonucleoprotein, PTB-binding 2
chr20_+_29685331 0.06 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr13_-_36164801 0.02 ENSDART00000169768
slc8a3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr10_+_4717721 0.02 ENSDART00000161789
palm2
paralemmin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
1.5 7.3 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
1.0 3.1 GO:0055004 atrial cardiac myofibril assembly(GO:0055004)
0.8 4.1 GO:0003197 endocardial cushion development(GO:0003197)
0.8 2.4 GO:0050864 regulation of B cell activation(GO:0050864)
0.6 6.3 GO:0015671 oxygen transport(GO:0015671)
0.4 2.2 GO:0021561 facial nerve development(GO:0021561)
0.4 5.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.4 1.8 GO:0015817 histidine transport(GO:0015817)
0.3 1.6 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.3 0.8 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 1.0 GO:0010996 response to auditory stimulus(GO:0010996)
0.2 0.9 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.2 0.6 GO:0032475 otolith formation(GO:0032475)
0.2 2.4 GO:0070831 basement membrane assembly(GO:0070831)
0.2 1.1 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.2 4.8 GO:0030278 regulation of ossification(GO:0030278)
0.1 0.4 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.9 GO:0044458 motile cilium assembly(GO:0044458)
0.1 3.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 3.5 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 4.1 GO:0060037 pharyngeal system development(GO:0060037)
0.1 1.5 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.1 0.7 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 2.8 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 0.5 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 1.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.4 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.1 2.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 2.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.0 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.2 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.0 2.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 1.6 GO:0070509 calcium ion import(GO:0070509)
0.0 0.5 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 2.4 GO:0008544 epidermis development(GO:0008544)
0.0 0.9 GO:0031638 zymogen activation(GO:0031638)
0.0 1.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 2.4 GO:0006338 chromatin remodeling(GO:0006338)
0.0 5.0 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 2.0 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.4 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 0.7 GO:0006936 muscle contraction(GO:0006936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.3 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.6 3.5 GO:0048179 activin receptor complex(GO:0048179)
0.5 8.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 4.1 GO:0005869 dynactin complex(GO:0005869)
0.3 2.4 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.7 GO:0097433 dense body(GO:0097433)
0.2 0.9 GO:0060091 kinocilium(GO:0060091)
0.2 3.7 GO:0005861 troponin complex(GO:0005861)
0.1 2.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.1 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 2.3 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 2.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.8 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.0 4.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.9 6.3 GO:0031720 haptoglobin binding(GO:0031720)
0.9 3.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.9 8.8 GO:0015026 coreceptor activity(GO:0015026)
0.7 7.3 GO:0001972 retinoic acid binding(GO:0001972)
0.5 3.7 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.5 1.8 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.3 2.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.3 1.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.4 GO:0016493 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) C-C chemokine receptor activity(GO:0016493)
0.2 2.8 GO:0017046 peptide hormone binding(GO:0017046)
0.2 0.7 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 5.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.7 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters(GO:0016894)
0.1 1.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 6.8 GO:0051015 actin filament binding(GO:0051015)
0.0 4.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 6.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 16.9 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 1.0 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.8 PID BMP PATHWAY BMP receptor signaling
0.2 2.8 PID ALK1 PATHWAY ALK1 signaling events
0.2 7.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.4 8.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 5.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 7.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK