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Results for hoxa5a

Z-value: 1.55

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Transcription factors associated with hoxa5a

Gene Symbol Gene ID Gene Info
hoxa5a
ENSDARG00000102501 homeobox A5a

Activity profile of hoxa5a motif

Sorted Z-values of hoxa5a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa5a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr21_-_32747592 8.46

chr7_+_17695289 8.40 ENSDART00000101601
cth1
cysteine three histidine 1
chr12_-_13692190 4.85 ENSDART00000152370
foxh1
forkhead box H1
chr24_-_14446593 4.80

chr7_-_55346967 4.62 ENSDART00000135304
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr19_-_20819101 4.62 ENSDART00000137590
dazl
deleted in azoospermia-like
chr5_+_26888744 4.53 ENSDART00000123635
sfrp1a
secreted frizzled-related protein 1a
chr21_-_2296253 4.43 ENSDART00000162867
zgc:66483
zgc:66483
chr10_-_43070342 4.35 ENSDART00000099270
CU326366.2
ENSDARG00000068593
chr11_-_44539778 4.03 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr22_-_38321005 3.91 ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr2_-_44924505 3.16 ENSDART00000113351
ncapd2
non-SMC condensin I complex, subunit D2
chr10_-_1933874 3.04 ENSDART00000101023
tdgf1
teratocarcinoma-derived growth factor 1
chr1_-_43299713 2.93 ENSDART00000138447
zgc:66472
zgc:66472
chr10_-_2915710 2.93 ENSDART00000002622
oclna
occludin a
chr11_-_15886860 2.86 ENSDART00000170731
zgc:173544
zgc:173544
chr21_-_32747544 2.80

chr2_+_56534374 2.65 ENSDART00000113964
POLR2E (1 of many)
RNA polymerase II subunit E
chr3_+_16692138 2.53 ENSDART00000023985
zgc:153952
zgc:153952
chr10_+_44853207 2.48 ENSDART00000169466
scarb1
scavenger receptor class B, member 1
chr21_+_43183522 2.42 ENSDART00000151350
aff4
AF4/FMR2 family, member 4
chr16_-_39245082 2.34 ENSDART00000058546
ebag9
estrogen receptor binding site associated, antigen, 9
chr12_-_10529153 2.16 ENSDART00000047769
myof
myoferlin
chr17_-_1524751 2.15 ENSDART00000112803
wdr20a
WD repeat domain 20a
chr1_+_18909507 2.14 ENSDART00000088933
ENSDART00000141579
fbxo10
F-box protein 10
chr17_-_38940072 2.07 ENSDART00000141177
slc24a4a
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr23_+_32102030 2.01 ENSDART00000145501
tpx2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr1_+_18909404 1.98 ENSDART00000088933
ENSDART00000141579
fbxo10
F-box protein 10
chr2_+_32863386 1.93 ENSDART00000056649
tmem53
transmembrane protein 53
chr18_+_39079744 1.93 ENSDART00000098729
zgc:171509
zgc:171509
chr12_-_10528974 1.92 ENSDART00000047769
myof
myoferlin
chr12_+_20222000 1.89 ENSDART00000150020
hbae5
hemoglobin, alpha embryonic 5
chr8_-_38284748 1.88 ENSDART00000102233
pdlim2
PDZ and LIM domain 2 (mystique)
chr9_-_10174409 1.82 ENSDART00000004745
hnmt
histamine N-methyltransferase
chr21_-_2350090 1.80 ENSDART00000168946
si:ch211-241b2.4
si:ch211-241b2.4
chr3_+_16692090 1.79 ENSDART00000023985
zgc:153952
zgc:153952
chr17_+_5680342 1.77 ENSDART00000156089
CU929322.1
ENSDARG00000096839
chr10_+_16914003 1.75 ENSDART00000177906
UNC13B
unc-13 homolog B
chr3_-_20944854 1.74 ENSDART00000109790
nlk1
nemo-like kinase, type 1
chr10_-_109097 1.72 ENSDART00000127228
ttc3
tetratricopeptide repeat domain 3
chr5_+_56988663 1.63 ENSDART00000074268
zgc:153929
zgc:153929
chr4_-_5766814 1.61 ENSDART00000021753
ccnc
cyclin C
chr8_-_39788989 1.59 ENSDART00000067843
zgc:162025
zgc:162025
chr7_+_26730804 1.58

chr13_-_11873326 1.57 ENSDART00000111438
mgea5
meningioma expressed antigen 5 (hyaluronidase)
chr4_-_26106485 1.56 ENSDART00000100611
si:ch211-244b2.3
si:ch211-244b2.3
chr23_-_6831711 1.55 ENSDART00000125393
FP102169.1
ENSDARG00000089210
chr2_-_37821146 1.55 ENSDART00000154124
nfatc4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr4_-_17654047 1.52

chr17_-_43041254 1.41 ENSDART00000124663
npc2
Niemann-Pick disease, type C2
chr2_-_48444730 1.36 ENSDART00000057957
itm2cb
integral membrane protein 2Cb
chr22_-_26112676 1.32

chr14_-_26199966 1.32 ENSDART00000054175
ENSDART00000145625
smad5
SMAD family member 5
chr17_-_10581958 1.32 ENSDART00000051526
jmjd7
jumonji domain containing 7
chr16_-_24916921 1.31 ENSDART00000153731
si:dkey-79d12.5
si:dkey-79d12.5
chr11_-_33605979 1.29 ENSDART00000171439
si:ch211-227n13.3
si:ch211-227n13.3
chr22_+_1445227 1.28 ENSDART00000164685
si:dkeyp-53d3.5
si:dkeyp-53d3.5
chr15_-_23756976 1.27 ENSDART00000141618
ercc2
excision repair cross-complementation group 2
chr13_-_25620394 1.27 ENSDART00000111567
sgpl1
sphingosine-1-phosphate lyase 1
chr15_-_47351885 1.27

chr11_-_6870810 1.26 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr7_+_73595871 1.25 ENSDART00000169756
HIST1H2BA (1 of many)
Histone H2B 1/2
chr11_-_30388949 1.24 ENSDART00000063775
ENSDARG00000043442
ENSDARG00000043442
chr14_-_26127173 1.20 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr1_-_52833426 1.19 ENSDART00000143349
zgc:66455
zgc:66455
chr19_+_7254917 1.18 ENSDART00000123934
hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr6_+_6505309 1.17 ENSDART00000065568
zgc:113227
zgc:113227
chr23_-_27647386 1.15

chr12_+_22507388 1.15 ENSDART00000168935
mfsd8
major facilitator superfamily domain containing 8
chr21_-_32747483 1.15

chr6_+_23218068 1.14 ENSDART00000164960
stx8
syntaxin 8
chr8_-_31706783 1.14 ENSDART00000061832
si:dkey-46a10.3
si:dkey-46a10.3
chr17_-_9806413 1.13 ENSDART00000021942
eapp
e2f-associated phosphoprotein
chr9_-_44797688 1.10

chr10_-_10755962 1.09 ENSDART00000137797
CT027791.1
ENSDARG00000093881
chr16_+_41004372 1.08 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr2_+_32842978 1.07 ENSDART00000143127
si:dkey-154p10.3
si:dkey-154p10.3
chr10_-_43070514 1.02

chr13_-_25620444 1.01 ENSDART00000111567
sgpl1
sphingosine-1-phosphate lyase 1
chr17_+_16102236 0.99 ENSDART00000156989
CT954240.1
ENSDARG00000097742
chr11_-_25019165 0.99 ENSDART00000130477
ENSDART00000079578
snai1a
snail family zinc finger 1a
chr11_+_30389309 0.94 ENSDART00000087909
tmem246
transmembrane protein 246
chr21_-_1618494 0.94 ENSDART00000124904
zgc:152948
zgc:152948
chr12_-_7201660 0.93 ENSDART00000152450
ipmkb
inositol polyphosphate multikinase b
chr9_-_12298632 0.93 ENSDART00000032344
nup35
nucleoporin 35
chr7_-_40359613 0.92 ENSDART00000173670
ube3c
ubiquitin protein ligase E3C
chr1_-_43300015 0.92 ENSDART00000138447
zgc:66472
zgc:66472
chr16_+_41004516 0.92 ENSDART00000058587
gbp
glycogen synthase kinase binding protein
chr18_+_22286036 0.91

chr24_-_14447519 0.90

chr3_+_32234155 0.89 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr10_+_43070478 0.88

chr17_-_27217309 0.85 ENSDART00000130080
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr11_-_44539726 0.83 ENSDART00000173360
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr11_+_3939876 0.81 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr22_+_37696341 0.81 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr21_-_2322963 0.81 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr2_-_37555425 0.81 ENSDART00000143496
arhgef18a
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr8_+_45339021 0.81

chr6_-_23966578 0.79 ENSDART00000164159
dr1
down-regulator of transcription 1
chr21_-_35291005 0.77 ENSDART00000134780
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr11_+_30389137 0.76 ENSDART00000087909
tmem246
transmembrane protein 246
chr11_-_7146819 0.75 ENSDART00000172879
smim7
small integral membrane protein 7
chr15_-_44581550 0.74

chr2_+_10209233 0.74 ENSDART00000160304
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr1_+_45147835 0.73 ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr19_-_11001651 0.72 ENSDART00000165630
ecm1a
extracellular matrix protein 1a
chr25_+_33486711 0.71 ENSDART00000121498
ice2
interactor of little elongator complex ELL subunit 2
chr2_+_8981028 0.69 ENSDART00000134308
zzz3
zinc finger, ZZ-type containing 3
chr6_+_23966336 0.68

chr2_-_22913885 0.67

chr16_-_39245193 0.66 ENSDART00000058546
ebag9
estrogen receptor binding site associated, antigen, 9
chr7_+_71573058 0.64 ENSDART00000166865
myl12.1
myosin, light chain 12, genome duplicate 1
chr13_-_16901290 0.64

chr3_-_26927151 0.63 ENSDART00000153542
CR954963.1
ENSDARG00000097153
chr3_+_27476229 0.56 ENSDART00000024453
usp7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr2_-_31728072 0.53 ENSDART00000113498
lrrcc1
leucine rich repeat and coiled-coil centrosomal protein 1
chr15_+_17322173 0.52 ENSDART00000169608
dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr12_-_10529236 0.52 ENSDART00000144283
myof
myoferlin
chr24_+_33916364 0.49 ENSDART00000136040
atg9b
autophagy related 9B
chr9_-_1046486 0.46 ENSDART00000161870
ino80da
INO80 complex subunit Da
chr11_-_37816180 0.46 ENSDART00000086516
klhdc8a
kelch domain containing 8A
chr9_-_746424 0.46 ENSDART00000082300
usp37
ubiquitin specific peptidase 37
chr2_+_32843040 0.45 ENSDART00000143127
si:dkey-154p10.3
si:dkey-154p10.3
chr1_+_45147775 0.43 ENSDART00000179047
map2k7
mitogen-activated protein kinase kinase 7
chr1_+_43347056 0.43

chr19_-_4934737 0.42 ENSDART00000110398
fbxl20
F-box and leucine-rich repeat protein 20
chr4_-_7644374 0.41 ENSDART00000157751
BX649411.1
ENSDARG00000101254
chr15_-_15294188 0.40 ENSDART00000155400
rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr19_+_4939815 0.39 ENSDART00000093402
cdk12
cyclin-dependent kinase 12
chr12_-_31609517 0.38 ENSDART00000080173
srsf2a
serine/arginine-rich splicing factor 2a
chr1_+_5492078 0.34 ENSDART00000140936
retreg2
reticulophagy regulator family member 2
chr15_+_42329433 0.34 ENSDART00000130404
scaf4b
SR-related CTD-associated factor 4b
chr25_+_7172658 0.34 ENSDART00000111151
peak1
pseudopodium-enriched atypical kinase 1
chr14_-_1186858 0.33 ENSDART00000106672
arl9
ADP-ribosylation factor-like 9
chr8_-_38284660 0.31 ENSDART00000102233
pdlim2
PDZ and LIM domain 2 (mystique)
chr2_+_24152953 0.29 ENSDART00000131030
gorasp1a
golgi reassembly stacking protein 1a
chr13_-_17598311 0.29 ENSDART00000013011
vdac2
voltage-dependent anion channel 2
chr15_+_23588063 0.28 ENSDART00000152517
si:dkey-182i3.9
si:dkey-182i3.9
chr21_+_17509116 0.28

chr4_-_75660728 0.28 ENSDART00000154142
ENSDART00000155070
si:dkey-172k15.3
si:dkey-172k15.3
chr14_+_10675644 0.24 ENSDART00000091169
abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr16_+_10666588 0.22 ENSDART00000091241
si:ch73-22o12.1
si:ch73-22o12.1
chr13_-_49294664 0.17 ENSDART00000165868
tomm20a
translocase of outer mitochondrial membrane 20
chr19_+_43524684 0.13

chr8_-_43733891 0.13 ENSDART00000166581
ep400
E1A binding protein p400
chr10_+_5025384 0.13 ENSDART00000031165
enoph1
enolase-phosphatase 1
chr16_-_2880109 0.11 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
chr8_-_23759198 0.11 ENSDART00000145894
zgc:195245
zgc:195245
chr11_+_10991763 0.11 ENSDART00000160488
itgb6
integrin, beta 6
chr3_+_27475771 0.08 ENSDART00000150953
usp7
ubiquitin specific peptidase 7 (herpes virus-associated)
chr14_-_1186789 0.06

chr16_-_21863723 0.00 ENSDART00000161640
gnl1
guanine nucleotide binding protein-like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
1.0 4.8 GO:0010159 specification of organ position(GO:0010159)
0.9 4.6 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.8 3.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.6 1.8 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.3 4.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 1.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.3 1.4 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.3 1.3 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.2 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.6 GO:0097065 anterior head development(GO:0097065)
0.2 2.0 GO:0034381 cholesterol efflux(GO:0033344) plasma lipoprotein particle clearance(GO:0034381)
0.2 0.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 1.9 GO:0015671 oxygen transport(GO:0015671)
0.2 4.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 4.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.9 GO:0006999 nuclear pore organization(GO:0006999)
0.1 2.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.3 GO:0060021 palate development(GO:0060021)
0.1 2.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 2.3 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 1.2 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.8 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 1.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.7 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.1 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 1.0 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.7 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 1.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 2.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.3 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.6 GO:0031647 regulation of protein stability(GO:0031647)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 5.4 GO:0000421 autophagosome membrane(GO:0000421)
0.2 0.8 GO:0017054 negative cofactor 2 complex(GO:0017054)
0.1 0.9 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.2 GO:0031941 filamentous actin(GO:0031941)
0.1 3.2 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 2.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 3.0 GO:0030141 secretory granule(GO:0030141)
0.0 3.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 2.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.5 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 4.1 GO:0000785 chromatin(GO:0000785)
0.0 0.7 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.6 GO:0005635 nuclear envelope(GO:0005635)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.4 4.6 GO:0008494 translation activator activity(GO:0008494)
0.4 2.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 2.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.3 3.0 GO:0070697 activin receptor binding(GO:0070697)
0.3 1.9 GO:0031720 haptoglobin binding(GO:0031720)
0.2 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.2 GO:0005537 mannose binding(GO:0005537)
0.2 1.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 5.7 GO:0046332 SMAD binding(GO:0046332)
0.1 2.2 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 4.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.7 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 4.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 1.2 GO:0048038 quinone binding(GO:0048038)
0.1 2.0 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 3.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 3.5 GO:0042393 histone binding(GO:0042393)
0.0 1.8 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.2 2.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 3.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.2 PID AURORA B PATHWAY Aurora B signaling
0.1 2.0 PID AURORA A PATHWAY Aurora A signaling
0.1 4.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 7.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 2.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 1.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein