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Results for hoxa9a+hoxa9b

Z-value: 1.41

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Transcription factors associated with hoxa9a+hoxa9b

Gene Symbol Gene ID Gene Info
hoxa9b
ENSDARG00000056819 homeobox A9b
hoxa9a
ENSDARG00000105013 homeobox A9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa9adr10_dc_chr19_+_20177128_20177172-0.918.1e-07Click!
hoxa9bdr10_dc_chr16_+_21109486_21109575-0.901.5e-06Click!

Activity profile of hoxa9a+hoxa9b motif

Sorted Z-values of hoxa9a+hoxa9b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa9a+hoxa9b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_32914487 5.78 ENSDART00000015547
cldng
claudin g
chr19_-_27966525 3.71 ENSDART00000142313
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr8_-_2557556 3.51 ENSDART00000140033
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
KN150456v1_-_19515 3.48 ENSDART00000168786
h1m
linker histone H1M
chr2_+_34984631 3.10 ENSDART00000141796
astn1
astrotactin 1
chr7_+_30355221 2.94 ENSDART00000173533
ENSDART00000052541
ccnb2
cyclin B2
chr20_-_20922072 2.87 ENSDART00000142618
ENSDART00000145601
ckbb
creatine kinase, brain b
chr17_+_19606608 2.83 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr17_-_4086835 2.80 ENSDART00000055379
gdf3
growth differentiation factor 3
chr5_-_23211957 2.73 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr12_-_22116694 2.66 ENSDART00000038310
ENSDART00000132731
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr14_+_34150130 2.59 ENSDART00000132193
ENSDART00000141058
wnt8a
BX927327.1
wingless-type MMTV integration site family, member 8a
ENSDARG00000105311
chr2_+_58943872 2.56 ENSDART00000158860
ENSDART00000067736
stk11
serine/threonine kinase 11
chr10_+_44853207 2.36 ENSDART00000169466
scarb1
scavenger receptor class B, member 1
chr19_-_15324823 2.29 ENSDART00000169883
phactr4a
phosphatase and actin regulator 4a
chr6_-_40451790 2.26 ENSDART00000103879
tatdn2
TatD DNase domain containing 2
chr21_-_13593659 2.20 ENSDART00000065817
pou5f3
POU domain, class 5, transcription factor 3
chr1_+_23866532 2.17 ENSDART00000076519
dctpp1
dCTP pyrophosphatase 1
chr14_+_32578253 2.13 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr25_-_36512943 2.10 ENSDART00000114508
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
KN150623v1_+_258 2.10

chr11_-_22663430 2.08 ENSDART00000154813
mdm4
MDM4, p53 regulator
chr7_+_26274687 2.04 ENSDART00000135313
tnk1
tyrosine kinase, non-receptor, 1
chr8_-_38322610 2.01 ENSDART00000134283
ENSDART00000132077
sorbs3
sorbin and SH3 domain containing 3
chr25_-_2932779 1.98 ENSDART00000149117
ENSDART00000137950
si:ch1073-296i8.2
si:ch1073-296i8.2
chr6_-_25065823 1.91 ENSDART00000167259
znf326
zinc finger protein 326
chr3_-_39316317 1.90

chr18_+_48188699 1.88

chr24_-_32259029 1.86 ENSDART00000048633
trdmt1
tRNA aspartic acid methyltransferase 1
chr14_-_32937536 1.85 ENSDART00000132850
stard14
START domain containing 14
chr21_+_15774697 1.84 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr21_+_15774822 1.79 ENSDART00000122015
fam169ab
family with sequence similarity 169, member Ab
chr3_+_44928323 1.78 ENSDART00000170913
zgc:112146
zgc:112146
chr7_-_37648061 1.77 ENSDART00000052368
heatr3
HEAT repeat containing 3
chr23_+_29017954 1.76 ENSDART00000140291
CR677513.1
ENSDARG00000093890
chr12_-_25058837 1.76 ENSDART00000135368
rhoq
ras homolog family member Q
chr22_+_21524515 1.74 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr7_+_1337856 1.72 ENSDART00000050687
lpcat4
lysophosphatidylcholine acyltransferase 4
chr7_-_19116999 1.71 ENSDART00000165680
ntn4
netrin 4
chr23_-_3778250 1.70 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr21_+_19958025 1.70

chr1_-_51567135 1.70 ENSDART00000143805
rab3da
RAB3D, member RAS oncogene family, a
chr13_+_13814142 1.67 ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr3_+_40113121 1.66 ENSDART00000074746
smcr8a
Smith-Magenis syndrome chromosome region, candidate 8a
chr15_+_24629719 1.65 ENSDART00000134622
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr20_-_23355244 1.65

chr21_-_3548863 1.63 ENSDART00000086492
atp8b1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr5_-_66145078 1.62 ENSDART00000041441
stip1
stress-induced phosphoprotein 1
chr6_-_42390995 1.61 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr3_-_40090673 1.60 ENSDART00000155969
flii
flightless I actin binding protein
chr15_+_24629858 1.56 ENSDART00000134622
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr16_-_43107682 1.51 ENSDART00000142003
nudt17
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr11_-_22663375 1.50 ENSDART00000154813
mdm4
MDM4, p53 regulator
chr7_+_13742576 1.50

KN150334v1_-_9585 1.48 ENSDART00000175935
CABZ01113810.1
ENSDARG00000107898
chr20_+_54404987 1.47 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr25_-_24440001 1.44 ENSDART00000156805
CR854832.1
ENSDARG00000096817
chr9_-_2522639 1.44 ENSDART00000137706
scrn3
secernin 3
chr5_+_19429620 1.43 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr22_+_25754857 1.42 ENSDART00000174421
AL929192.1
ENSDARG00000106684
chr20_-_34851706 1.41 ENSDART00000148066
znf395b
zinc finger protein 395b
chr14_-_31375046 1.39 ENSDART00000173274
map7d3
MAP7 domain containing 3
chr3_-_26060787 1.38 ENSDART00000113843
ypel3
yippee-like 3
chr8_-_2557506 1.37 ENSDART00000140033
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr9_-_48516764 1.36 ENSDART00000012938
phgdh
phosphoglycerate dehydrogenase
chr10_-_1933761 1.35 ENSDART00000101023
tdgf1
teratocarcinoma-derived growth factor 1
chr16_-_34240818 1.35 ENSDART00000054026
rcc1
regulator of chromosome condensation 1
chr5_+_19429500 1.35 ENSDART00000168868
ankrd13a
ankyrin repeat domain 13A
chr1_+_30925269 1.34 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr25_-_2932820 1.34 ENSDART00000149117
ENSDART00000137950
si:ch1073-296i8.2
si:ch1073-296i8.2
chr6_-_25065745 1.34 ENSDART00000165170
znf326
zinc finger protein 326
chr17_+_15780112 1.33 ENSDART00000027667
ENSDART00000161637
rragd
ras-related GTP binding D
chr21_-_20908880 1.32 ENSDART00000079701
rnf180
ring finger protein 180
chr17_+_15780156 1.31 ENSDART00000027667
ENSDART00000161637
rragd
ras-related GTP binding D
chr16_+_28335377 1.31 ENSDART00000059035
fam188a
family with sequence similarity 188, member A
chr9_-_30448622 1.30 ENSDART00000129926
si:dkey-100n23.5
si:dkey-100n23.5
chr3_+_13034056 1.28

chr17_+_25313170 1.28 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr7_-_19989419 1.28 ENSDART00000127699
si:ch73-335l21.4
si:ch73-335l21.4
chr25_+_15901398 1.28 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr10_-_8088063 1.25 ENSDART00000099031
zgc:136254
zgc:136254
chr5_-_31796734 1.25 ENSDART00000142095
fbxw2
F-box and WD repeat domain containing 2
chr12_-_7551118 1.24 ENSDART00000152556
FAM13C
family with sequence similarity 13 member C
chr23_-_39253291 1.24

chr1_+_57267909 1.24 ENSDART00000152640
BX469930.2
ENSDARG00000096615
chr7_-_38363533 1.23 ENSDART00000173861
c1qtnf4
C1q and TNF related 4
chr11_+_14285767 1.23 ENSDART00000171347
si:ch211-262i1.6
si:ch211-262i1.6
chr3_+_58417512 1.22 ENSDART00000154122
si:ch211-165g14.1
si:ch211-165g14.1
chr7_+_13742622 1.22

chr8_+_3373066 1.22 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr1_+_35253862 1.21 ENSDART00000139636
zgc:152968
zgc:152968
chr17_-_4086971 1.20 ENSDART00000055379
gdf3
growth differentiation factor 3
chr8_-_44247277 1.20

chr17_+_11519212 1.20

chr2_-_58805035 1.20 ENSDART00000159735
mau2
MAU2 sister chromatid cohesion factor
chr3_-_14545237 1.19 ENSDART00000133850
gadd45gip1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr24_-_6304289 1.18 ENSDART00000140212
zgc:174877
zgc:174877
chr19_-_35286549 1.18 ENSDART00000016057
ctnnal1
catenin (cadherin-associated protein), alpha-like 1
chr6_-_53145759 1.18 ENSDART00000154429
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr23_-_43916621 1.18 ENSDART00000015777
abce1
ATP-binding cassette, sub-family E (OABP), member 1
chr1_-_54505313 1.17 ENSDART00000100619
ENSDART00000163796
LUC7L2
zgc:158803
chr14_+_31265616 1.15

chr12_+_29017351 1.12

chr22_+_11114268 1.12 ENSDART00000047442
bcor
BCL6 corepressor
chr4_+_16197 1.12 ENSDART00000166174
ENSDARG00000100660
ENSDARG00000100660
chr5_-_40524177 1.12 ENSDART00000083561
mtmr12
myotubularin related protein 12
chr15_+_24629778 1.11 ENSDART00000134622
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr16_-_17678748 1.11 ENSDART00000017142
m6pr
mannose-6-phosphate receptor (cation dependent)
chr16_-_34471672 1.10 ENSDART00000172162
CR626886.2
ENSDARG00000105308
chr24_+_26257058 1.10 ENSDART00000133684
si:ch211-230g15.5
si:ch211-230g15.5
chr3_+_9504996 1.09 ENSDART00000171467
si:dkey-29p9.3
si:dkey-29p9.3
chr16_+_32060609 1.08 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr13_+_51485084 1.08 ENSDART00000163741
pwwp2b
PWWP domain containing 2B
chr13_-_35782121 1.05 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr1_+_30925353 1.04 ENSDART00000057880
poll
polymerase (DNA directed), lambda
chr3_-_59690168 1.04 ENSDART00000035878
cdr2l
cerebellar degeneration-related protein 2-like
chr2_-_44924505 1.03 ENSDART00000113351
ncapd2
non-SMC condensin I complex, subunit D2
chr20_-_52002087 1.03 ENSDART00000041476
mia3
melanoma inhibitory activity family, member 3
chr6_+_18894174 1.02 ENSDART00000165806
stk11ip
serine/threonine kinase 11 interacting protein
chr5_-_35997345 1.01 ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr8_+_15231620 1.01 ENSDART00000020386
gclm
glutamate-cysteine ligase, modifier subunit
chr15_-_37037547 1.01

chr14_+_25950198 0.97 ENSDART00000113804
ENSDART00000159054
CCDC69
coiled-coil domain containing 69
chr18_-_35432838 0.97 ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr3_+_58417635 0.96 ENSDART00000154122
si:ch211-165g14.1
si:ch211-165g14.1
chr8_+_25072241 0.96 ENSDART00000143922
atxn7l2b
ataxin 7-like 2b
chr22_-_11024649 0.95 ENSDART00000105823
ENSDART00000159995
insrb
insulin receptor b
chr20_+_29685379 0.95 ENSDART00000178617
adam17b
ADAM metallopeptidase domain 17b
chr18_-_35432655 0.95 ENSDART00000137663
snrpa
small nuclear ribonucleoprotein polypeptide A
chr25_+_3169073 0.93

chr22_+_11114168 0.93 ENSDART00000047442
bcor
BCL6 corepressor
chr10_+_33758581 0.93 ENSDART00000141650
b3glctb
beta 3-glucosyltransferase b
chr12_+_4651222 0.93 ENSDART00000128145
kansl1a
KAT8 regulatory NSL complex subunit 1a
chr15_+_29241472 0.92

chr11_-_13283709 0.92 ENSDART00000164978
mast3b
microtubule associated serine/threonine kinase 3b
chr3_-_40112966 0.92 ENSDART00000154562
top3a
topoisomerase (DNA) III alpha
chr17_-_2419079 0.91 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr18_+_41559512 0.91 ENSDART00000059135
bcl7bb
B-cell CLL/lymphoma 7B, b
chr13_-_22831005 0.90 ENSDART00000143112
tspan15
tetraspanin 15
chr23_+_3778066 0.90 ENSDART00000141880
smim29
small integral membrane protein 29
chr24_-_20946041 0.90 ENSDART00000140786
qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr10_-_1933874 0.90 ENSDART00000101023
tdgf1
teratocarcinoma-derived growth factor 1
chr6_-_11576632 0.89 ENSDART00000151717
march7
membrane-associated ring finger (C3HC4) 7
chr16_+_29574449 0.87 ENSDART00000148450
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr1_-_529071 0.87 ENSDART00000147610
si:ch73-41e3.7
si:ch73-41e3.7
chr3_-_40626599 0.87 ENSDART00000004923
smurf1
SMAD specific E3 ubiquitin protein ligase 1
chr23_+_43916520 0.87 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr19_-_34529880 0.87 ENSDART00000158677
ENSDART00000112004
si:dkey-184p18.2
si:dkey-184p18.2
chr8_-_38322559 0.87 ENSDART00000134283
ENSDART00000132077
sorbs3
sorbin and SH3 domain containing 3
chr13_-_24778226 0.86

KN149698v1_-_88818 0.86

chr6_-_14841372 0.86 ENSDART00000167436
CU929521.1
ENSDARG00000097482
chr13_+_13814262 0.86 ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr1_+_11490451 0.86 ENSDART00000142081
stra6l
STRA6-like
chr13_-_24778352 0.85

chr5_-_28914505 0.85 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr10_-_25448712 0.85 ENSDART00000140023
grik1a
glutamate receptor, ionotropic, kainate 1a
chr20_-_54812675 0.84 ENSDART00000059872
ppp1r35
protein phosphatase 1, regulatory subunit 35
chr17_-_25612341 0.84 ENSDART00000126201
ENSDART00000105503
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr8_+_3372903 0.84 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr13_-_22831037 0.83 ENSDART00000057641
tspan15
tetraspanin 15
chr2_-_32755182 0.83 ENSDART00000041146
nrbp2a
nuclear receptor binding protein 2a
chr2_+_21527785 0.83 ENSDART00000136498
si:dkey-29d8.3
si:dkey-29d8.3
chr19_+_3115685 0.83 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
hsf1
heat shock transcription factor 1
chr7_+_38257950 0.82 ENSDART00000109495
ENSDART00000173804
nudt19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr12_+_13050549 0.82

chr11_-_44107913 0.82

chr16_+_29442108 0.81 ENSDART00000050535
rrnad1
ribosomal RNA adenine dimethylase domain containing 1
chr3_+_52290252 0.81 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr15_-_14653696 0.81 ENSDART00000172195
adck4
aarF domain containing kinase 4
chr11_+_5522377 0.81 ENSDART00000013203
cse1l
CSE1 chromosome segregation 1-like (yeast)
chr10_-_33307845 0.81 ENSDART00000169064
bcl7ba
B-cell CLL/lymphoma 7B, a
chr25_+_16784585 0.80 ENSDART00000020259
zgc:77158
zgc:77158
chr5_+_63596241 0.80 ENSDART00000111282
qsox2
quiescin Q6 sulfhydryl oxidase 2
KN150604v1_-_7233 0.80

chr6_-_53145582 0.80 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr19_-_15324909 0.79 ENSDART00000169883
phactr4a
phosphatase and actin regulator 4a
chr2_+_35613093 0.79 ENSDART00000098734
cacybp
calcyclin binding protein
chr2_+_22753634 0.79 ENSDART00000171853
LMO4
zgc:56628
chr5_+_55763413 0.79

chr11_-_40192951 0.78 ENSDART00000102750
tnfrsf1b
tumor necrosis factor receptor superfamily, member 1B
chr3_+_52290504 0.78 ENSDART00000018908
slc27a1a
solute carrier family 27 (fatty acid transporter), member 1a
chr11_-_16261061 0.78 ENSDART00000115085
lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr5_+_61279071 0.78 ENSDART00000168808
si:dkeyp-117b8.4
si:dkeyp-117b8.4
chr22_-_9796735 0.78 ENSDART00000144395
BX539307.3
ENSDARG00000093730
chr20_+_2625716 0.77 ENSDART00000058775
zgc:101562
zgc:101562
chr25_+_2252667 0.77 ENSDART00000172905
zmp:0000000932
zmp:0000000932
chr22_+_21524430 0.77 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr16_-_9939549 0.77 ENSDART00000148528
grhl2a
grainyhead-like transcription factor 2a
chr9_-_50106512 0.77

chr17_-_25612397 0.76 ENSDART00000126201
ENSDART00000105503
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr10_-_33307992 0.76 ENSDART00000169064
bcl7ba
B-cell CLL/lymphoma 7B, a
chr15_-_1519615 0.76 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr22_+_1643493 0.76 ENSDART00000167767
BX649416.1
ENSDARG00000098230
chr23_-_3778530 0.76 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr16_-_34471475 0.76 ENSDART00000172162
CR626886.2
ENSDARG00000105308
chr11_+_23796452 0.76 ENSDART00000128309
zc3h11a
zinc finger CCCH-type containing 11A
chr3_+_24510974 0.75 ENSDART00000148414
ENSDART00000055590
zgc:113411
zgc:113411
chr19_-_31455278 0.75 ENSDART00000133101
ENSDART00000136213
bzw2
basic leucine zipper and W2 domains 2
chr16_-_29517367 0.74 ENSDART00000148960
si:ch211-113g11.6
si:ch211-113g11.6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.9 2.7 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.7 2.2 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.6 2.6 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 3.1 GO:0097009 energy homeostasis(GO:0097009)
0.5 2.2 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.5 1.6 GO:0051055 medium-chain fatty acid transport(GO:0001579) temperature homeostasis(GO:0001659) negative regulation of lipid biosynthetic process(GO:0051055)
0.5 2.1 GO:0032263 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.5 1.5 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.5 2.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.4 3.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 2.9 GO:1901911 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4 2.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 1.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.4 2.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.4 2.2 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.4 2.9 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 1.7 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 4.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.3 0.9 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.3 1.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 1.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 0.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 2.7 GO:0030259 lipid glycosylation(GO:0030259)
0.3 2.4 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.3 1.9 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.3 1.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.7 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.2 5.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 2.0 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2 1.3 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.2 0.6 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.2 1.8 GO:0034381 plasma lipoprotein particle clearance(GO:0034381)
0.2 1.6 GO:0031204 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.7 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.8 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.6 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:0007589 body fluid secretion(GO:0007589)
0.1 0.4 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.2 GO:1901797 negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 3.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 4.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 2.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.8 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 2.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.8 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.4 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.0 GO:0035459 cargo loading into vesicle(GO:0035459)
0.1 0.4 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 2.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 1.2 GO:0006415 translational termination(GO:0006415)
0.1 1.5 GO:0051014 actin filament severing(GO:0051014)
0.1 1.6 GO:0009408 response to heat(GO:0009408)
0.1 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 3.5 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 2.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 2.9 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.9 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 1.0 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.1 1.0 GO:1902622 engulfment of apoptotic cell(GO:0043652) regulation of neutrophil migration(GO:1902622)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0072019 homeostasis of number of cells within a tissue(GO:0048873) proximal convoluted tubule development(GO:0072019)
0.0 0.3 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 1.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.0 0.7 GO:0030301 cholesterol transport(GO:0030301)
0.0 1.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.8 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.7 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.8 GO:0000154 rRNA modification(GO:0000154)
0.0 1.6 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 1.1 GO:0034968 histone lysine methylation(GO:0034968)
0.0 1.8 GO:0072659 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.6 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.7 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 1.5 GO:0001666 response to hypoxia(GO:0001666)
0.0 0.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.3 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.3 GO:0006213 pyrimidine nucleoside metabolic process(GO:0006213)
0.0 0.2 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.8 GO:0032259 methylation(GO:0032259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0044609 DBIRD complex(GO:0044609)
0.9 2.7 GO:0035339 SPOTS complex(GO:0035339)
0.6 2.6 GO:0002144 cytosolic tRNA wobble base thiouridylase complex(GO:0002144)
0.6 2.6 GO:0097189 apoptotic body(GO:0097189)
0.3 1.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.3 1.6 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.3 2.0 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.6 GO:0005784 Sec61 translocon complex(GO:0005784)
0.2 0.6 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 1.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.5 GO:0000346 transcription export complex(GO:0000346)
0.2 2.0 GO:0005869 dynactin complex(GO:0005869)
0.2 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.6 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.0 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.5 GO:0044545 NSL complex(GO:0044545)
0.1 0.3 GO:0034709 methylosome(GO:0034709)
0.1 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.0 GO:0030904 retromer complex(GO:0030904)
0.1 5.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.2 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 2.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 3.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0017054 negative cofactor 2 complex(GO:0017054)
0.0 0.9 GO:0016529 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 1.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 1.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004617 phosphoglycerate dehydrogenase activity(GO:0004617)
0.7 2.1 GO:0052657 guanine phosphoribosyltransferase activity(GO:0052657)
0.5 2.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.5 1.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 2.9 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.4 1.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.4 2.9 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.3 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.3 2.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 1.4 GO:0016805 dipeptidase activity(GO:0016805)
0.2 0.7 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.2 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.9 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 0.8 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 2.2 GO:0070697 activin receptor binding(GO:0070697)
0.2 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 1.0 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.6 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.2 1.1 GO:0005537 mannose binding(GO:0005537)
0.2 3.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 3.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 0.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 2.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 1.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.1 1.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 2.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.0 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 1.3 GO:0030552 cAMP binding(GO:0030552)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0035197 siRNA binding(GO:0035197)
0.1 1.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.7 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 3.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.1 6.5 GO:0005125 cytokine activity(GO:0005125)
0.1 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 3.1 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 1.6 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.1 2.6 GO:0000049 tRNA binding(GO:0000049)
0.1 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 2.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 2.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.9 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 5.7 GO:0042802 identical protein binding(GO:0042802)
0.0 3.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 3.7 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 6.3 GO:0003924 GTPase activity(GO:0003924)
0.0 1.3 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215) chemorepellent activity(GO:0045499)
0.0 1.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 4.4 GO:0003682 chromatin binding(GO:0003682)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.2 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 0.0 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216) 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.6 GO:0016874 ligase activity(GO:0016874)
0.0 0.6 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.9 GO:0008168 methyltransferase activity(GO:0008168)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.1 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 5.1 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.5 PID ATM PATHWAY ATM pathway
0.1 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 5.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.0 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID SHP2 PATHWAY SHP2 signaling
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.3 3.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.3 1.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 1.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 2.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 2.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.5 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 1.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 2.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.1 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 1.4 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules