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Results for hoxb2a

Z-value: 0.74

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Transcription factors associated with hoxb2a

Gene Symbol Gene ID Gene Info
ENSDARG00000000175 homeobox B2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb2adr10_dc_chr3_+_23621843_23621906-0.273.2e-01Click!

Activity profile of hoxb2a motif

Sorted Z-values of hoxb2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb2a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_+_25740782 1.58 ENSDART00000021620
claudin d
chr11_-_6442588 1.18 ENSDART00000137879
zgc:162969
chr8_-_23759076 0.93 ENSDART00000145894
zgc:195245
chr18_+_20571619 0.92 ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr10_-_44713495 0.88 ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr20_+_37023072 0.82 ENSDART00000155058
ENSDARG00000096706
chr23_+_28396415 0.76 ENSDART00000142179
baculoviral IAP repeat containing 5b
KN150699v1_-_15078 0.74 ENSDART00000159861
ENSDARG00000098739
chr5_+_29193876 0.73 ENSDART00000045410
Thy-1 cell surface antigen
chr18_+_6417959 0.72 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr21_-_32027717 0.72 ENSDART00000131651
ENSDARG00000073961
chr5_+_58936399 0.70

chr1_-_18118467 0.69 ENSDART00000142026
si:dkey-167i21.2
chr20_-_38884093 0.68 ENSDART00000153430
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr21_+_34053590 0.68 ENSDART00000147519
ENSDART00000158115
ENSDART00000029599
ENSDART00000145123
myotubularin related protein 1b
chr6_+_28218420 0.68 ENSDART00000171216
ENSDART00000171377
si:ch73-14h10.2
chr3_+_28729443 0.64 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr1_-_54570813 0.64 ENSDART00000098615
nanos homolog 3
chr24_+_8702288 0.62 ENSDART00000114810
synaptonemal complex protein 2-like
chr20_-_23527234 0.61 ENSDART00000004625
zygote arrest 1
chr11_+_17849608 0.61 ENSDART00000020283
RNA pseudouridylate synthase domain containing 4
chr2_-_57020663 0.60

chr16_+_42567707 0.60 ENSDART00000166640
si:ch211-215k15.5
chr13_-_18564182 0.59 ENSDART00000176809
sideroflexin 3
chr7_-_24604255 0.58 ENSDART00000173920
adenosine deaminase domain containing 2
chr11_-_6442490 0.58 ENSDART00000137879
zgc:162969
chr17_+_16038358 0.58 ENSDART00000155336
si:ch73-204p21.2
chr12_-_33716108 0.58 ENSDART00000161265
progressive external ophthalmoplegia 1
chr6_-_3821922 0.56 ENSDART00000171944
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr23_-_33692244 0.56

chr4_-_75732882 0.55

chr16_+_9509875 0.54 ENSDART00000162073
ENSDART00000146174
KIAA0947-like (H. sapiens)
chr5_-_18502344 0.54 ENSDART00000137022
ENSDART00000090494
ENSDART00000165701
golgin A3
chr5_-_29818204 0.54 ENSDART00000098285
activating transcription factor 5a
chr21_+_34053739 0.53 ENSDART00000147519
myotubularin related protein 1b
chr10_-_21404605 0.52 ENSDART00000125167
avidin
chr23_-_35691369 0.52 ENSDART00000142369
major facilitator superfamily domain containing 5
chr16_+_46443800 0.52 ENSDART00000131072
rapunzel 2
chr3_-_19890717 0.51 ENSDART00000104118
ENSDART00000170199
ataxin 7-like 3
chr7_+_17564492 0.50 ENSDART00000173807
echinoderm microtubule associated protein like 3
chr14_-_8634381 0.50 ENSDART00000129030
zgc:153681
chr2_+_11335733 0.50 ENSDART00000055737
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr10_-_35313462 0.50 ENSDART00000139107
proline rich 11
chr1_+_518777 0.50 ENSDART00000109083
thioredoxin-like 4B
chr17_+_26704439 0.49 ENSDART00000114927
NRDE-2, necessary for RNA interference, domain containing
chr2_-_54224744 0.48

chr17_-_25630635 0.47 ENSDART00000149060
protein phosphatase 1, catalytic subunit, beta isozyme
chr7_-_71214600 0.46 ENSDART00000042492
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr15_-_43954665 0.45 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr1_+_23866532 0.45 ENSDART00000076519
dCTP pyrophosphatase 1
chr10_-_34971926 0.45 ENSDART00000141201
cyclin A1
chr10_-_44713414 0.45 ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr5_-_26164728 0.45 ENSDART00000140392
ring finger protein 181
chr14_+_25208174 0.44 ENSDART00000079016
THO complex 3
chr10_+_516924 0.44 ENSDART00000128275
neuropeptide FF receptor 1 like 3
chr18_+_20571460 0.43 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr22_+_8973724 0.41 ENSDART00000106414
ribonuclease/angiogenin inhibitor 1
chr1_+_50547385 0.41 ENSDART00000132141
BTB (POZ) domain containing 3a
chr1_+_50547341 0.41 ENSDART00000132141
BTB (POZ) domain containing 3a
chr5_-_4483970 0.41

chr18_+_18011759 0.41 ENSDART00000147797
ENSDARG00000011498
chr12_+_46281592 0.41 ENSDART00000149326
Usher syndrome 1Gb (autosomal recessive)
chr14_-_33605295 0.41 ENSDART00000168546
zinc finger, DHHC-type containing 24
chr10_-_25448712 0.41 ENSDART00000140023
glutamate receptor, ionotropic, kainate 1a
chr7_+_17564307 0.41 ENSDART00000158005
echinoderm microtubule associated protein like 3
chr1_+_18118735 0.40 ENSDART00000078610
solute carrier family 25, member 51a
chr13_-_37340209 0.40

chr17_-_4086971 0.40 ENSDART00000055379
growth differentiation factor 3
chr5_-_29818325 0.39 ENSDART00000098285
activating transcription factor 5a
chr12_-_30244575 0.39 ENSDART00000152981
tudor domain containing 1
chr15_-_16241412 0.39 ENSDART00000156352
si:ch211-259g3.4
chr6_+_18941135 0.38 ENSDART00000044519
connexin 44.2
chr13_-_42274486 0.38 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr24_+_29278310 0.38 ENSDART00000101641
protein arginine methyltransferase 6
chr23_-_26241101 0.38

chr8_+_26377369 0.38 ENSDART00000087151
aminomethyltransferase
chr25_-_31352866 0.38 ENSDART00000041740
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr5_-_18502442 0.37 ENSDART00000165639
golgin A3
chr18_+_18011562 0.37 ENSDART00000005027
ENSDARG00000011498
chr17_+_12504341 0.36 ENSDART00000139918
GPN-loop GTPase 1
chr5_+_32687626 0.36 ENSDART00000146759
mediator complex subunit 22
chr16_+_9509747 0.36 ENSDART00000162073
ENSDART00000146174
KIAA0947-like (H. sapiens)
chr15_-_16241500 0.36 ENSDART00000156352
si:ch211-259g3.4
chr17_+_28689850 0.36 ENSDART00000126967
striatin, calmodulin binding protein 3
KN149710v1_+_38638 0.35

chr17_+_16038103 0.35 ENSDART00000155005
si:ch73-204p21.2
chr16_+_9509605 0.35 ENSDART00000162073
ENSDART00000146174
KIAA0947-like (H. sapiens)
chr19_-_6925090 0.35 ENSDART00000081568
transcription factor 19 (SC1), like
chr1_+_21244242 0.35 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr24_-_14446593 0.35

chr1_-_44970931 0.35 ENSDART00000042158
serine hydrolase-like
chr2_+_6341404 0.34 ENSDART00000076700
zona pellucida glycoprotein 3b
chr8_-_21110262 0.34 ENSDART00000143192
carnitine palmitoyltransferase 2
chr12_+_19077980 0.34 ENSDART00000066393
pdgfa associated protein 1a
chr8_+_9955720 0.34

chr3_-_15060501 0.34 ENSDART00000037906
HIRA interacting protein 3
chr9_+_33310981 0.33

chr7_-_48393883 0.33 ENSDART00000006378
cyclin-dependent kinase inhibitor 1Ca
chr14_+_15845853 0.33 ENSDART00000160973
polymerase (RNA) I polypeptide A
chr3_-_39912816 0.33 ENSDART00000102540
lethal giant larvae homolog 1 (Drosophila)
chr25_-_24440292 0.33 ENSDART00000156805
ENSDARG00000096817
chr4_-_20457108 0.32 ENSDART00000003621
ENSDART00000132356
siaz-interacting nuclear protein
chr21_+_1622040 0.32 ENSDART00000148540
ferrochelatase
chr19_-_5186692 0.32 ENSDART00000037007
triosephosphate isomerase 1a
chr8_+_25126238 0.32 ENSDART00000136505
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr19_+_42657913 0.32 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr5_+_26165043 0.32 ENSDART00000144169
si:ch211-102c2.8
chr19_+_46371377 0.32 ENSDART00000169710
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr19_+_32614657 0.31 ENSDART00000022667
family with sequence similarity 8, member A1a
chr17_-_43725091 0.31

chr14_-_26199859 0.31 ENSDART00000054175
ENSDART00000145625
SMAD family member 5
chr24_+_39630741 0.30 ENSDART00000132939
defective in cullin neddylation 1 domain containing 3
chr23_+_32102030 0.30 ENSDART00000145501
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr12_+_30252424 0.30 ENSDART00000153364
si:ch211-225b10.4
chr14_+_17092009 0.29 ENSDART00000129838
ring finger protein 212
chr1_-_22617455 0.29 ENSDART00000137567
small integral membrane protein 14
chr18_+_20571513 0.29 ENSDART00000136710
WEE1 homolog 2 (S. pombe)
chr19_-_19806070 0.29 ENSDART00000165206
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b
chr20_+_38555185 0.29 ENSDART00000020153
aarF domain containing kinase 3
chr1_-_25750237 0.29 ENSDART00000125690
integrator complex subunit 12
chr13_-_12257051 0.29 ENSDART00000124784
COMM domain containing 8
chr2_-_37371987 0.28 ENSDART00000056522
SKI-like proto-oncogene a
chr8_+_50964745 0.28 ENSDART00000013870
ENSDARG00000007359
chr18_+_18011800 0.28 ENSDART00000147797
ENSDARG00000011498
chr10_+_516885 0.28 ENSDART00000128275
neuropeptide FF receptor 1 like 3
chr5_+_32687543 0.28 ENSDART00000123210
mediator complex subunit 22
chr18_+_20571400 0.28 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr8_+_20108592 0.27

KN150703v1_+_15225 0.27

chr18_+_20571785 0.27 ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr12_+_3632548 0.27

chr23_+_44470297 0.26 ENSDART00000149842
methylphosphate capping enzyme
chr20_+_54544931 0.26

chr24_+_5863597 0.26 ENSDART00000161104
microtubule associated serine/threonine kinase-like
chr9_-_9729041 0.26 ENSDART00000175212
G protein-coupled receptor 156
chr21_-_39132951 0.26 ENSDART00000065143
unc-119 homolog b (C. elegans)
chr7_-_64173039 0.26 ENSDART00000172619
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_+_54811485 0.25 ENSDART00000073549
snail family zinc finger 3
chr5_+_6391432 0.25 ENSDART00000170564
ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr10_+_25986401 0.25 ENSDART00000138516
ubiquitin-fold modifier 1
chr10_+_2656840 0.25

chr4_+_5789600 0.25 ENSDART00000059440
si:ch73-352p4.8
chr18_-_18886144 0.24 ENSDART00000127182
ADP-ribosylation factor-like 2 binding protein
chr11_-_44738541 0.24 ENSDART00000168066
arylformamidase
chr3_-_34208507 0.24 ENSDART00000151634
trinucleotide repeat containing 6C1
chr3_-_32741894 0.24 ENSDART00000075277
zgc:113090
chr21_+_26689954 0.24 ENSDART00000065392
calmodulin 3b (phosphorylase kinase, delta)
chr22_-_7688508 0.24

chr16_+_42567668 0.24 ENSDART00000166640
si:ch211-215k15.5
chr3_-_26113336 0.24 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr7_-_39874079 0.24 ENSDART00000173634
WD repeat domain 60
chr10_-_32550351 0.24 ENSDART00000129395
UV radiation resistance associated gene
chr7_-_17564136 0.24 ENSDART00000091272
ENSDART00000173757
ECSIT signalling integrator
chr3_+_48811662 0.23 ENSDART00000023814
protein kinase C substrate 80K-H
chr16_-_42105733 0.23 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr11_-_33956671 0.23 ENSDART00000098472
transmembrane protein 44
chr20_-_34126039 0.23 ENSDART00000033817
SCY1-like, kinase-like 3
chr19_+_31998646 0.23 ENSDART00000132182
geminin, DNA replication inhibitor
chr12_+_46281511 0.22 ENSDART00000149326
Usher syndrome 1Gb (autosomal recessive)
chr20_-_25546095 0.22 ENSDART00000145034
mitochondrial ribosomal protein L19
chr12_-_17564384 0.22 ENSDART00000079065
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr2_-_55584106 0.22 ENSDART00000169382
ENSDART00000097874
tropomyosin 4b
chr15_+_45738963 0.22

chr9_-_35073289 0.22 ENSDART00000011163
acetylserotonin O-methyltransferase-like
chr6_-_41141242 0.22 ENSDART00000128723
ENSDART00000151055
solute carrier family 6 member 22, tandem duplicate 1
chr19_+_770458 0.22 ENSDART00000062518
glutathione S-transferase rho
chr15_-_44581550 0.21

chr15_-_17233876 0.21 ENSDART00000101718
cullin 5a
chr19_+_32317583 0.21 ENSDART00000151218
tumor protein D52
chr18_+_19467527 0.21 ENSDART00000079695
zwilch kinetochore protein
chr8_-_21039978 0.21 ENSDART00000137606
ENSDART00000146532
zgc:112962
chr13_+_36797201 0.21 ENSDART00000026313
thioredoxin-related transmembrane protein 1
chr18_-_43890836 0.21 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr11_-_44539726 0.21 ENSDART00000173360
microtubule-associated protein 1 light chain 3 gamma
chr8_-_4562273 0.20 ENSDART00000025535
septin 5a
chr9_-_2522639 0.20 ENSDART00000137706
secernin 3
chr6_-_41141280 0.20 ENSDART00000001861
solute carrier family 6 member 22, tandem duplicate 1
chr16_-_42105636 0.20 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr4_-_14894468 0.20

chr7_-_54752916 0.19

chr12_+_46281623 0.19 ENSDART00000149326
Usher syndrome 1Gb (autosomal recessive)
chr2_-_33703921 0.19 ENSDART00000147439
ATPase, H+ transporting, lysosomal V0 subunit b
chr21_-_30957754 0.19 ENSDART00000065503
post-GPI attachment to proteins 2
chr12_+_19077847 0.19 ENSDART00000066393
pdgfa associated protein 1a
chr5_-_3103278 0.19

chr22_-_3986398 0.19 ENSDART00000169317
ENSDART00000171262
ubiquitin-like with PHD and ring finger domains 1
chr24_+_23571714 0.19 ENSDART00000080332
COP9 signalosome subunit 5
chr24_+_34183407 0.19 ENSDART00000143995
zgc:92591
chr3_-_26112995 0.19 ENSDART00000103741
protein phosphatase 4, catalytic subunit a
chr10_+_2554914 0.18 ENSDART00000016103
nucleoredoxin-like 2
chr2_+_6341345 0.18 ENSDART00000058256
zona pellucida glycoprotein 3b
chr11_+_17849528 0.18 ENSDART00000020283
RNA pseudouridylate synthase domain containing 4
chr25_-_36691657 0.18 ENSDART00000153789
ring finger and WD repeat domain 3
chr21_+_15815265 0.18 ENSDART00000154468
ENSDARG00000096884
chr2_+_10209233 0.18 ENSDART00000160304
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr8_+_28362546 0.18 ENSDART00000062682
adiponectin receptor 1b
chr21_-_25765319 0.17 ENSDART00000101219
methyltransferase like 27
chr22_+_2074020 0.17 ENSDART00000106540
zinc finger protein 1161
chr8_+_39640881 0.17 ENSDART00000040330
ENSDART00000045529
ENSDART00000159852
protein kinase, AMP-activated, beta 1 non-catalytic subunit, b
chr7_-_10318692 0.17 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0060631 regulation of meiosis I(GO:0060631)
0.3 0.8 GO:0050957 equilibrioception(GO:0050957)
0.3 0.8 GO:0051311 meiotic metaphase plate congression(GO:0051311)
0.2 0.6 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.4 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.5 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.5 GO:0009223 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.8 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.4 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 1.6 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.3 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 1.0 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 0.3 GO:1900186 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.5 GO:0030719 P granule organization(GO:0030719)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.6 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 1.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.3 GO:0060021 palate development(GO:0060021)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.3 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0001840 neural plate development(GO:0001840)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.5 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.5 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:0017177 glucosidase II complex(GO:0017177)
0.1 0.4 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.4 GO:0071546 pi-body(GO:0071546)
0.0 0.9 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.6 GO:0043186 P granule(GO:0043186)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.4 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.6 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.3 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.5 GO:0009374 biotin binding(GO:0009374)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.2 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.5 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.1 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0000215 tRNA 2'-phosphotransferase activity(GO:0000215) 2'-phosphotransferase activity(GO:0008665)
0.0 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 1.9 GO:0042393 histone binding(GO:0042393)
0.0 1.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.7 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism