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DANIO-CODE

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Results for hoxb3a

Z-value: 1.31

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Transcription factors associated with hoxb3a

Gene Symbol Gene ID Gene Info
hoxb3a
ENSDARG00000029263 homeobox B3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb3adr10_dc_chr3_+_23567458_23567493-0.893.1e-06Click!

Activity profile of hoxb3a motif

Sorted Z-values of hoxb3a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb3a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_-_23759076 7.17 ENSDART00000145894
zgc:195245
zgc:195245
chr19_-_18664720 6.39 ENSDART00000108627
snx10a
sorting nexin 10a
chr6_+_23476669 4.89

chr5_+_37303599 4.12 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr25_+_5845303 4.03 ENSDART00000163948
ENSDARG00000053246
ENSDARG00000053246
chr20_-_14218080 3.73 ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr2_-_38305602 3.57 ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr10_-_21587697 3.21 ENSDART00000029122
zgc:165539
zgc:165539
chr2_-_26941084 3.01 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr13_-_18564182 2.82 ENSDART00000176809
sfxn3
sideroflexin 3
chr21_-_32027717 2.79 ENSDART00000131651
ENSDARG00000073961
ENSDARG00000073961
chr9_+_18821640 2.70 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
KN150030v1_-_22572 2.64 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr18_-_43890836 2.63 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr24_+_19270877 2.61

chr11_+_12754166 2.57 ENSDART00000123445
ENSDART00000163364
ENSDART00000066122
rtel1
regulator of telomere elongation helicase 1
chr20_+_14218237 2.55 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr19_-_18664670 2.42 ENSDART00000108627
snx10a
sorting nexin 10a
chr25_-_1243081 2.35 ENSDART00000156062
calml4b
calmodulin-like 4b
KN150663v1_-_3381 2.10

chr20_-_37910887 2.09 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr8_-_28359022 2.07 ENSDART00000062693
ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr1_-_51075777 2.06 ENSDART00000152745
snrpb2
small nuclear ribonucleoprotein polypeptide B2
chr6_+_36862078 2.05 ENSDART00000104160
ENSDARG00000070746
ENSDARG00000070746
chr22_+_17235696 2.01 ENSDART00000134798
tdrd5
tudor domain containing 5
chr17_-_1907622 2.01 ENSDART00000156489
xgb
x globin
chr7_-_32598812 1.97

chr10_-_17214368 1.96

chr14_-_33141111 1.94 ENSDART00000147059
lamp2
lysosomal-associated membrane protein 2
chr23_-_32267833 1.94

chr2_+_6341404 1.87 ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr16_-_40633986 1.85 ENSDART00000170815
BX324007.2
ENSDARG00000100586
chr23_-_33692244 1.82

chr13_+_24549364 1.80 ENSDART00000139854
zgc:66426
zgc:66426
chr25_+_17764396 1.79 ENSDART00000146845
pth1a
parathyroid hormone 1a
chr13_-_8360779 1.78 ENSDART00000058107
mcfd2
multiple coagulation factor deficiency 2
chr2_+_30198819 1.73 ENSDART00000004903
rdh10b
retinol dehydrogenase 10b
chr14_-_9686650 1.69

chr24_-_39315552 1.69

chr6_+_18941186 1.59 ENSDART00000044519
cx44.2
connexin 44.2
chr17_-_1907667 1.59 ENSDART00000156489
xgb
x globin
chr22_-_21873054 1.58

chr25_+_15176959 1.57 ENSDART00000045659
tcp11l1
t-complex 11, testis-specific-like 1
chr9_+_38832959 1.55 ENSDART00000110651
slc12a8
solute carrier family 12, member 8
chr7_-_20330881 1.51 ENSDART00000169750
si:dkey-19b23.11
si:dkey-19b23.11
chr14_+_14536088 1.49 ENSDART00000158291
slbp
stem-loop binding protein
chr19_-_1571878 1.49

chr20_-_14218236 1.49 ENSDART00000168434
si:ch211-223m11.2
si:ch211-223m11.2
chr22_-_26254136 1.47 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr2_+_38305772 1.46 ENSDART00000170672
nedd8l
neural precursor cell expressed, developmentally down-regulated 8, like
chr6_-_1685041 1.45

chr19_+_21209328 1.44 ENSDART00000142463
txnl4a
thioredoxin-like 4A
chr24_-_9838947 1.43 ENSDART00000138576
zgc:171977
zgc:171977
chr3_-_30955799 1.41 ENSDART00000103421
zgc:153292
zgc:153292
chr6_+_18941135 1.39 ENSDART00000044519
cx44.2
connexin 44.2
chr7_-_48394268 1.38 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr2_-_26940965 1.38 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr8_-_19215929 1.36 ENSDART00000147172
abhd17ab
abhydrolase domain containing 17Ab
KN150030v1_-_22613 1.36 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr25_-_19510499 1.35 ENSDART00000166824
gtse1
G-2 and S-phase expressed 1
chr6_+_18941289 1.35 ENSDART00000044519
cx44.2
connexin 44.2
chr14_-_49973159 1.34 ENSDART00000124192
si:dkeyp-121d2.7
si:dkeyp-121d2.7
chr21_-_36768113 1.33 ENSDART00000018350
cnot8
CCR4-NOT transcription complex, subunit 8
chr16_+_52961277 1.33 ENSDART00000163151
cep72
centrosomal protein 72
chr20_+_27188382 1.32 ENSDART00000062094
tmem251
transmembrane protein 251
chr7_-_26226924 1.32 ENSDART00000058910
sox19b
SRY (sex determining region Y)-box 19b
chr21_-_40915270 1.31 ENSDART00000008593
yipf5
Yip1 domain family, member 5
chr20_+_29306863 1.31 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr2_+_38305689 1.30 ENSDART00000170672
nedd8l
neural precursor cell expressed, developmentally down-regulated 8, like
chr3_+_3687340 1.28 ENSDART00000113616
zgc:171426
zgc:171426
chr11_-_2437396 1.27

chr13_+_28655338 1.26 ENSDART00000039028
nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component
chr12_+_22459177 1.26 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr21_+_11742219 1.25 ENSDART00000081661
nudt2
nudix (nucleoside diphosphate linked moiety X)-type motif 2
chr5_+_60782855 1.23 ENSDART00000074073
alkbh4
alkB homolog 4, lysine demthylase
chr8_+_11287550 1.19 ENSDART00000115057
tjp2b
tight junction protein 2b (zona occludens 2)
chr7_+_12675166 1.16 ENSDART00000027329
fth1a
ferritin, heavy polypeptide 1a
chr13_+_33578737 1.16 ENSDART00000161465
CABZ01087953.1
ENSDARG00000104106
chr20_+_29306677 1.15 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr20_-_36510718 1.15

chr25_+_19642595 1.14

chr2_-_17721810 1.14 ENSDART00000100201
ENSDART00000141188
st3gal3b
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr12_+_22459218 1.13 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr2_+_1645259 1.13 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr14_-_30564987 1.13 ENSDART00000173451
si:ch211-126c2.4
si:ch211-126c2.4
chr5_+_12971972 1.13 ENSDART00000132406
cnnm4b
cyclin and CBS domain divalent metal cation transport mediator 4b
chr12_-_4212149 1.11 ENSDART00000059298
zgc:92313
zgc:92313
chr8_-_44247277 1.11

chr5_+_25133592 1.09 ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr2_-_36845638 1.08

chr12_-_33256934 1.07 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr25_-_19510386 1.06 ENSDART00000147223
gtse1
G-2 and S-phase expressed 1
chr13_+_28655433 1.05 ENSDART00000039028
nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component
chr2_+_10209233 1.05 ENSDART00000160304
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr5_+_32751876 1.04

chr10_-_25808063 1.04 ENSDART00000134176
postna
periostin, osteoblast specific factor a
chr25_+_15177176 1.03 ENSDART00000045659
tcp11l1
t-complex 11, testis-specific-like 1
chr18_+_27593121 1.03 ENSDART00000134714
cd82b
CD82 molecule b
chr1_+_43822319 1.03 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr1_-_53220810 0.99 ENSDART00000010543
ltv1
LTV1 ribosome biogenesis factor
chr21_-_30217360 0.98 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr11_+_11319810 0.96 ENSDART00000162486
si:dkey-23f9.4
si:dkey-23f9.4
chr24_+_16402587 0.96 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_-_12024136 0.95 ENSDART00000111919
sp2
sp2 transcription factor
chr3_-_27470798 0.95 ENSDART00000077734
zgc:66160
zgc:66160
chr3_+_30956719 0.94 ENSDART00000129564
si:dkey-66i24.8
si:dkey-66i24.8
chr6_+_40835073 0.94 ENSDART00000011931
ruvbl1
RuvB-like AAA ATPase 1
chr15_+_15920149 0.93 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr8_+_26040518 0.92 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_15517767 0.91 ENSDART00000115022
zgc:66474
zgc:66474
chr10_-_21971084 0.91 ENSDART00000174954
CABZ01031892.1
ENSDARG00000107280
chr16_-_31386496 0.88

chr15_+_24860161 0.85 ENSDART00000139689
gosr1
golgi SNAP receptor complex member 1
chr6_+_36862148 0.85 ENSDART00000104160
ENSDARG00000070746
ENSDARG00000070746
chr4_-_75683584 0.84 ENSDART00000075770
zgc:162948
zgc:162948
chr15_+_34734212 0.83 ENSDART00000099776
tspan13a
tetraspanin 13a
chr6_-_57642148 0.81

chr3_+_30956652 0.81 ENSDART00000129564
si:dkey-66i24.8
si:dkey-66i24.8
chr5_+_37303707 0.80 ENSDART00000097754
ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr23_+_34021303 0.78 ENSDART00000136104
si:ch211-148l7.4
si:ch211-148l7.4
chr2_-_32264046 0.78 ENSDART00000146452
fam49ba
family with sequence similarity 49, member Ba
chr16_-_40634046 0.77 ENSDART00000170815
BX324007.2
ENSDARG00000100586
chr8_-_28359072 0.76 ENSDART00000062693
ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr21_-_30217568 0.76 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr1_+_43822153 0.75 ENSDART00000147702
zdhhc5a
zinc finger, DHHC-type containing 5a
chr8_-_17974316 0.74 ENSDART00000122730
acot11b
acyl-CoA thioesterase 11b
chr6_-_54049582 0.73

chr13_-_30011574 0.72 ENSDART00000110157
tysnd1
trypsin domain containing 1
chr14_-_36057494 0.71 ENSDART00000052562
spata4
spermatogenesis associated 4
chr19_+_1743359 0.70 ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr25_-_28630138 0.70

chr12_-_4212095 0.70 ENSDART00000059298
zgc:92313
zgc:92313
chr21_+_3017338 0.69

chr3_-_60394265 0.69 ENSDART00000053502
DXO
decapping exoribonuclease
chr20_+_29306945 0.67 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr12_-_43310712 0.67 ENSDART00000178532
ENSDART00000179029
BX321882.2
ENSDARG00000109101
chr2_-_47827343 0.67 ENSDART00000056882
cul3a
cullin 3a
chr24_-_36227144 0.66

chr17_-_32417510 0.65 ENSDART00000145487
klf11b
Kruppel-like factor 11b
chr12_-_18997267 0.63 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr4_+_5147577 0.62 ENSDART00000067392
tigarb
tp53-induced glycolysis and apoptosis regulator b
chr23_+_34021480 0.62 ENSDART00000136104
si:ch211-148l7.4
si:ch211-148l7.4
chr22_-_21872864 0.61 ENSDART00000158501
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr8_-_17132057 0.61 ENSDART00000143920
mrps36
mitochondrial ribosomal protein S36
chr1_-_44874299 0.61

chr7_-_40359613 0.61 ENSDART00000173670
ube3c
ubiquitin protein ligase E3C
chr22_+_17235538 0.61 ENSDART00000134798
tdrd5
tudor domain containing 5
chr22_+_699477 0.61 ENSDART00000017305
znf76
zinc finger protein 76
KN149789v1_-_7443 0.60

chr20_+_38555185 0.60 ENSDART00000020153
adck3
aarF domain containing kinase 3
chr16_-_52030972 0.60 ENSDART00000012055
rpl28
ribosomal protein L28
chr8_-_17974364 0.60 ENSDART00000133666
acot11b
acyl-CoA thioesterase 11b
chr9_+_16304358 0.59 ENSDART00000154326
si:ch211-261p9.4
si:ch211-261p9.4
chr20_+_25687135 0.59 ENSDART00000063122
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr23_+_38313746 0.59 ENSDART00000129593
znf217
zinc finger protein 217
chr12_+_22459371 0.58 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr2_+_6341345 0.58 ENSDART00000058256
zp3b
zona pellucida glycoprotein 3b
chr5_+_60973192 0.58 ENSDART00000134387
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr24_-_34794856 0.57 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr5_+_12972081 0.57 ENSDART00000132406
cnnm4b
cyclin and CBS domain divalent metal cation transport mediator 4b
chr20_+_29315074 0.57 ENSDART00000024528
emc7
ER membrane protein complex subunit 7
chr3_+_19536018 0.56 ENSDART00000006490
tlk2
tousled-like kinase 2
chr24_-_38757042 0.56 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr22_-_26254217 0.56 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr7_-_22361507 0.55 ENSDART00000165245
si:dkey-112a7.4
si:dkey-112a7.4
chr22_-_6972182 0.55

chr8_+_52328005 0.54 ENSDART00000125241
dbnlb
drebrin-like b
chr3_-_27470857 0.54 ENSDART00000077734
zgc:66160
zgc:66160
chr19_+_3265362 0.53 ENSDART00000020344
zgc:86598
zgc:86598
chr21_-_35291005 0.53 ENSDART00000134780
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr5_-_25133456 0.52 ENSDART00000051566
zgc:101016
zgc:101016
chr11_+_43924766 0.52 ENSDART00000179206
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr21_-_11106675 0.51 ENSDART00000167666
dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr6_-_37766424 0.51 ENSDART00000149722
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr12_-_42212968 0.51 ENSDART00000171075
zgc:111868
zgc:111868
chr5_-_11779717 0.49 ENSDART00000143646
BX276096.1
ENSDARG00000093726
chr17_-_21258714 0.48 ENSDART00000157518
hspa12a
heat shock protein 12A
chr3_-_23442774 0.48

chr6_+_7257043 0.47 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr16_+_9835124 0.46 ENSDART00000020859
pip5k1ab
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr5_+_65364654 0.43 ENSDART00000016019
jak2b
Janus kinase 2b
chr20_+_30710653 0.43

chr13_-_30011613 0.43 ENSDART00000110157
tysnd1
trypsin domain containing 1
chr13_-_48884956 0.42

chr18_-_39207375 0.42 ENSDART00000131354
si:ch211-235f12.2
si:ch211-235f12.2
chr24_-_24859135 0.41 ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr6_+_36861678 0.40 ENSDART00000104160
ENSDARG00000070746
ENSDARG00000070746
chr14_+_21522672 0.40 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr1_-_39801699 0.38 ENSDART00000114659
maml3
mastermind-like transcriptional coactivator 3
chr24_+_7798743 0.37 ENSDART00000134975
zgc:101569
zgc:101569
chr5_+_65364856 0.37 ENSDART00000016019
jak2b
Janus kinase 2b
chr5_+_1439387 0.37

chr9_-_41072138 0.36 ENSDART00000066424
pofut2
protein O-fucosyltransferase 2
chr20_+_29307283 0.34 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr6_+_27906010 0.34 ENSDART00000161775
cep63
centrosomal protein 63
chr24_-_39315521 0.33

chr8_-_43782381 0.33 ENSDART00000144239
ulk1a
unc-51 like autophagy activating kinase 1a
chr6_-_48419131 0.32 ENSDART00000090528
rhoca
ras homolog family member Ca
chr25_+_34433321 0.29 ENSDART00000042678
ENSDART00000158092
vps4a
vacuolar protein sorting 4a homolog A (S. cerevisiae)
chr21_-_13565401 0.28 ENSDART00000151547
pnpla7a
patatin-like phospholipase domain containing 7a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0070986 left/right axis specification(GO:0070986)
0.9 2.6 GO:0090656 t-circle formation(GO:0090656)
0.4 6.0 GO:2000344 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.3 1.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.3 1.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.3 2.6 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 1.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.2 2.5 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 0.7 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 2.8 GO:0045116 protein neddylation(GO:0045116)
0.2 0.8 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.2 1.0 GO:0035264 multicellular organism growth(GO:0035264)
0.2 0.9 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.2 0.6 GO:1900543 negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.1 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 3.0 GO:0051014 actin filament severing(GO:0051014)
0.1 1.2 GO:0006167 AMP biosynthetic process(GO:0006167) ATP biosynthetic process(GO:0006754)
0.1 1.2 GO:0070989 oxidative demethylation(GO:0070989)
0.1 0.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 1.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 1.0 GO:0015671 oxygen transport(GO:0015671)
0.1 1.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.9 GO:0009206 GTP biosynthetic process(GO:0006183) purine nucleoside triphosphate biosynthetic process(GO:0009145) purine ribonucleoside triphosphate biosynthetic process(GO:0009206)
0.1 0.2 GO:0050864 regulation of lymphocyte mediated immunity(GO:0002706) positive regulation of adaptive immune response(GO:0002821) positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002824) regulation of B cell activation(GO:0050864)
0.1 1.0 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 2.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 2.8 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.6 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.8 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 2.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:0098869 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0099645 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 1.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.6 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 1.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 1.3 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 3.8 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 2.3 GO:0006310 DNA recombination(GO:0006310)
0.0 0.5 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0033391 chromatoid body(GO:0033391)
0.7 2.7 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.6 1.9 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 2.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 1.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 0.9 GO:0097255 R2TP complex(GO:0097255)
0.2 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 2.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 1.2 GO:0070938 contractile ring(GO:0070938)
0.1 0.6 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 2.1 GO:0005685 U1 snRNP(GO:0005685)
0.1 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.5 GO:0002102 podosome(GO:0002102)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 2.5 GO:0005930 axoneme(GO:0005930)
0.1 11.0 GO:0010008 endosome membrane(GO:0010008)
0.1 2.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 7.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.4 2.8 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.4 2.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 6.0 GO:0032190 acrosin binding(GO:0032190)
0.3 1.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.2 2.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 0.6 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 4.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 0.9 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.6 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 0.9 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.5 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.6 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 2.8 GO:0031386 protein tag(GO:0031386)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.1 1.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 2.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.9 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 8.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 2.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.2 GO:0032451 demethylase activity(GO:0032451)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 5.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.7 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 2.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres