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Results for hoxb7a

Z-value: 0.69

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Transcription factors associated with hoxb7a

Gene Symbol Gene ID Gene Info
hoxb7a
ENSDARG00000056030 homeobox B7a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb7adr10_dc_chr3_+_23561502_23561521-0.853.3e-05Click!

Activity profile of hoxb7a motif

Sorted Z-values of hoxb7a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb7a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_2373601 2.06 ENSDART00000113774
si:ch211-188c16.1
si:ch211-188c16.1
chr9_+_21982644 1.45 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr10_-_21404605 1.45 ENSDART00000125167
avd
avidin
chr3_-_39912816 1.37 ENSDART00000102540
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr21_+_34053739 1.32 ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr16_-_43061368 1.31 ENSDART00000113714
mtx1a
metaxin 1a
chr3_-_19890717 1.26 ENSDART00000104118
ENSDART00000170199
atxn7l3
ataxin 7-like 3
chr18_-_43890836 1.23 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr21_-_13026036 1.21 ENSDART00000135623
fam219aa
family with sequence similarity 219, member Aa
chr1_+_22160932 1.20 ENSDART00000016488
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr6_+_9663119 1.20 ENSDART00000169544
ENSDART00000005573
tmem237b
transmembrane protein 237b
chr25_-_13394261 1.19 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr17_+_16082472 1.16 ENSDART00000133154
znf395a
zinc finger protein 395a
chr2_+_15379961 1.16 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr2_+_15379717 1.06 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr9_+_21982679 1.05 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr10_-_31129270 1.04 ENSDART00000146116
panx3
pannexin 3
chr10_-_31129217 1.01 ENSDART00000146116
panx3
pannexin 3
chr21_-_33998148 0.98 ENSDART00000047515
ENSDART00000138575
ENSDART00000170749
rnf145b
ring finger protein 145b
chr8_+_23806179 0.98 ENSDART00000040362
mapk14a
mitogen-activated protein kinase 14a
chr5_+_6005049 0.89

chr7_+_7463565 0.88 ENSDART00000091099
ino80b
INO80 complex subunit B
chr21_-_33998091 0.86 ENSDART00000047515
ENSDART00000138575
ENSDART00000170749
rnf145b
ring finger protein 145b
chr2_+_15380054 0.86 ENSDART00000058484
cnn3b
calponin 3, acidic b
chr21_+_34053590 0.81 ENSDART00000147519
ENSDART00000158115
ENSDART00000029599
ENSDART00000145123
mtmr1b
myotubularin related protein 1b
chr25_-_28630138 0.76

chr4_-_765957 0.75 ENSDART00000128743
tmem214
transmembrane protein 214
chr9_+_21982756 0.72 ENSDART00000059652
rev1
REV1, polymerase (DNA directed)
chr6_+_59580554 0.68

chr21_-_33998117 0.67 ENSDART00000047515
ENSDART00000138575
ENSDART00000170749
rnf145b
ring finger protein 145b
chr14_+_47368951 0.67 ENSDART00000060577
tmem33
transmembrane protein 33
chr21_-_13026077 0.66 ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr23_-_25853364 0.65 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr21_-_33998051 0.60 ENSDART00000047515
ENSDART00000138575
ENSDART00000170749
rnf145b
ring finger protein 145b
chr18_+_14651021 0.58 ENSDART00000166679
cirh1a
cirrhosis, autosomal recessive 1A (cirhin)
chr17_+_16082983 0.57 ENSDART00000133154
znf395a
zinc finger protein 395a
chr5_+_20640396 0.56 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr15_-_43402935 0.52 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr23_+_39569262 0.51 ENSDART00000031616
mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr3_-_36460498 0.47 ENSDART00000161501
rrn3
RRN3 homolog, RNA polymerase I transcription factor
chr24_-_17261929 0.44 ENSDART00000153858
BX005392.2
ENSDARG00000096996
chr7_+_21006509 0.43 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr4_-_1952230 0.41 ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr9_+_55395276 0.40 ENSDART00000029528
mospd2
motile sperm domain containing 2
chr23_+_28882409 0.39 ENSDART00000078171
pex14
peroxisomal biogenesis factor 14
chr17_-_15221715 0.38 ENSDART00000039165
styx
serine/threonine/tyrosine interacting protein
chr6_+_7257043 0.37 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr5_-_23171454 0.34 ENSDART00000135153
TBC1D8B
TBC1 domain family member 8B
chr3_+_18621758 0.34 ENSDART00000156747
AL772362.1
ENSDARG00000097552
KN150706v1_+_7627 0.33

chr25_-_35094522 0.32 ENSDART00000153827
clpxb
caseinolytic mitochondrial matrix peptidase chaperone subunit b
chr15_+_15920149 0.29 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr13_-_36672606 0.28 ENSDART00000179242
sav1
salvador family WW domain containing protein 1
chr22_-_19077300 0.26 ENSDART00000166295
polrmt
polymerase (RNA) mitochondrial (DNA directed)
chr23_-_25853331 0.26 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr16_+_42763933 0.24 ENSDART00000023452
dpy19l1l
dpy-19-like 1, like (H. sapiens)
chr5_+_20640468 0.23 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr15_-_36490729 0.22

chr17_-_49355906 0.19 ENSDART00000162563
znf292a
zinc finger protein 292a
chr6_+_59580339 0.19

chr8_-_25015215 0.18 ENSDART00000170511
nfyal
nuclear transcription factor Y, alpha, like
chr23_-_25853220 0.17 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr16_-_52961072 0.16

chr5_+_57055662 0.12 ENSDART00000166545
fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr17_+_8642686 0.11 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr4_-_766308 0.11 ENSDART00000128743
tmem214
transmembrane protein 214
chr2_+_50873843 0.09

chr4_-_1952201 0.06 ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr16_+_42763696 0.02 ENSDART00000023452
dpy19l1l
dpy-19-like 1, like (H. sapiens)
chr7_+_6814762 0.01 ENSDART00000001649
actn3b
actinin alpha 3b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.5 3.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.2 1.0 GO:1901741 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) positive regulation of myoblast fusion(GO:1901741)
0.2 1.4 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 2.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.7 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.1 0.4 GO:0043393 regulation of protein binding(GO:0043393)
0.1 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.4 GO:0022615 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.8 GO:1900746 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341) regulation of vascular endothelial growth factor signaling pathway(GO:1900746) regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.1 0.5 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 2.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 2.9 GO:0061515 myeloid cell development(GO:0061515)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.2 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.0 3.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.5 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.2 GO:0060027 convergent extension involved in gastrulation(GO:0060027)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0005921 gap junction(GO:0005921)
0.2 1.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.4 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 1.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0017125 deoxycytidyl transferase activity(GO:0017125)
0.4 1.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.3 1.4 GO:0009374 biotin binding(GO:0009374)
0.2 2.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 2.0 GO:0022829 wide pore channel activity(GO:0022829)
0.2 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 0.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.5 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0070042 rRNA (uridine-N3-)-methyltransferase activity(GO:0070042)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 3.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0003724 RNA helicase activity(GO:0003724)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 3.2 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo