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Results for hoxb8a+hoxb8b

Z-value: 1.40

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Transcription factors associated with hoxb8a+hoxb8b

Gene Symbol Gene ID Gene Info
hoxb8b
ENSDARG00000054025 homeobox B8b
hoxb8a
ENSDARG00000056027 homeobox B8a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb8bdr10_dc_chr12_+_27026112_270261600.894.8e-06Click!
hoxb8adr10_dc_chr3_+_23557320_235574170.895.2e-06Click!

Activity profile of hoxb8a+hoxb8b motif

Sorted Z-values of hoxb8a+hoxb8b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb8a+hoxb8b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_-_5440923 5.00 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr13_+_30673907 4.60 ENSDART00000053946
cxcl12a
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr3_+_30790513 3.65 ENSDART00000130422
cldni
claudin i
chr20_-_29517770 3.53 ENSDART00000147464
ryr3
ryanodine receptor 3
chr7_+_42124857 3.47 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr25_+_24520476 3.40

chr3_-_34363698 3.13

chr23_+_36023748 3.11

chr23_+_32573474 2.98 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr3_+_33168814 2.96 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr24_-_28814066 2.89 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr5_+_49103778 2.84 ENSDART00000155405
CR751602.2
ENSDARG00000098045
chr21_-_22510751 2.65 ENSDART00000169870
myo5b
myosin VB
chr15_-_31687 2.60

chr14_-_24463906 2.59 ENSDART00000126199
slit3
slit homolog 3 (Drosophila)
chr9_-_20562293 2.58 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr14_+_21999898 2.53

chr19_+_20209561 2.52 ENSDART00000168833
CR382300.1
ENSDARG00000098798
chr14_+_25168063 2.49 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr1_+_25378105 2.45 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr25_+_15551288 2.43 ENSDART00000137375
spon1b
spondin 1b
chr20_-_7303735 2.42 ENSDART00000100060
dsc2l
desmocollin 2 like
chr10_-_42157835 2.42 ENSDART00000141500
ENSDART00000156626
BX005309.1
ENSDARG00000093535
chr6_+_14822990 2.40 ENSDART00000149949
pou3f3b
POU class 3 homeobox 3b
chr8_-_34077387 2.35 ENSDART00000159208
ENSDART00000040126
ENSDART00000048994
ENSDART00000098822
pbx3b
pre-B-cell leukemia homeobox 3b
chr19_-_3183062 2.30 ENSDART00000122816
si:ch211-80h18.1
si:ch211-80h18.1
chr6_+_14823185 2.27 ENSDART00000149202
pou3f3b
POU class 3 homeobox 3b
chr3_-_34208423 2.24 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr5_-_62747812 2.20

chr18_+_21419735 2.18 ENSDART00000144523
necab2
N-terminal EF-hand calcium binding protein 2
chr6_-_14821305 2.09

chr4_+_13811932 2.08 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr21_-_23271127 2.05 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr17_+_52736192 1.95 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr24_+_18804086 1.94 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr1_-_18709814 1.93 ENSDART00000145224
rbm47
RNA binding motif protein 47
chr11_+_6809190 1.91 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr25_+_15551474 1.87 ENSDART00000137375
spon1b
spondin 1b
chr24_+_34227202 1.84 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr23_+_24711233 1.82

chr20_-_7303804 1.82 ENSDART00000100060
dsc2l
desmocollin 2 like
chr15_+_21231406 1.81 ENSDART00000038499
CR626907.1
ENSDARG00000077872
chr14_+_4489377 1.80 ENSDART00000041468
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr9_-_23406315 1.79 ENSDART00000159256
kif5c
kinesin family member 5C
chr11_+_3940085 1.79 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr16_+_21121428 1.66

chr11_+_13470883 1.64 ENSDART00000011362
arrdc2
arrestin domain containing 2
chr15_+_24628386 1.63 ENSDART00000148022
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr16_+_46435014 1.59 ENSDART00000144000
rpz2
rapunzel 2
chr17_-_52735250 1.59

chr13_+_23152038 1.58 ENSDART00000171676
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr8_-_52426509 1.55 ENSDART00000015081
ENSDARG00000011208
ENSDARG00000011208
chr5_-_24365811 1.54 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr1_-_25377787 1.52

chr22_+_18364282 1.50 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr5_-_35143549 1.50 ENSDART00000157881
ophn1
oligophrenin 1
chr13_-_5440751 1.49 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr10_+_31358236 1.48 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr16_+_10885785 1.48 ENSDART00000161969
atp1a3b
ATPase, Na+/K+ transporting, alpha 3b polypeptide
chr5_+_44407763 1.46 ENSDART00000010786
dmrt2a
doublesex and mab-3 related transcription factor 2a
chr7_+_31608828 1.44 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr12_-_26314881 1.43 ENSDART00000178687
myoz1b
myozenin 1b
chr13_-_5440558 1.42 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr5_-_24365560 1.42 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr5_+_296856 1.42

chr8_+_18552850 1.40 ENSDART00000177476
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr2_-_57133471 1.38

chr23_-_32378111 1.32 ENSDART00000143772
dgkaa
diacylglycerol kinase, alpha a
chr2_-_9848848 1.32 ENSDART00000056901
zgc:153615
zgc:153615
chr18_+_5707066 1.32

chr7_-_25426346 1.31 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr20_+_20772543 1.28 ENSDART00000152481
rtn1b
reticulon 1b
chr21_+_43674754 1.28 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr1_+_50547214 1.25 ENSDART00000132244
btbd3a
BTB (POZ) domain containing 3a
chr3_+_59491893 1.24 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr2_-_36058327 1.24 ENSDART00000003550
nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr2_-_50638153 1.23 ENSDART00000108900
cntnap2b
contactin associated protein-like 2b
chr16_-_50139709 1.22

chr5_-_62747914 1.21

chr21_+_13063614 1.21

chr21_-_36886505 1.18 ENSDART00000113678
wwc1
WW and C2 domain containing 1
chr7_+_53485273 1.16 ENSDART00000158160
ENSDART00000163261
neo1a
neogenin 1a
chr1_-_46292847 1.13 ENSDART00000125032
pknox1.2
pbx/knotted 1 homeobox 1.2
chr7_-_18346474 1.12

chr15_+_24628435 1.11 ENSDART00000139885
dhrs13b
dehydrogenase/reductase (SDR family) member 13b
chr25_-_31291943 1.11 ENSDART00000175104
lamb4
laminin, beta 4
chr24_-_14447773 1.10

chr14_+_6647838 1.09 ENSDART00000060998
nme5
NME/NM23 family member 5
chr9_+_32267615 1.08

chr3_+_23621843 1.08 ENSDART00000146636
hoxb2a
homeobox B2a
chr19_+_5562107 1.07 ENSDART00000082080
jupb
junction plakoglobin b
chr12_-_34621359 1.07

chr3_+_27615311 1.05

chr7_-_34854886 1.05 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr12_-_7902815 1.02 ENSDART00000088100
ank3b
ankyrin 3b
chr10_-_27780050 1.02 ENSDART00000138149
si:dkey-33o22.1
si:dkey-33o22.1
chr22_+_35113233 0.97 ENSDART00000123066
srfa
serum response factor a
chr22_-_22337268 0.96

chr11_-_25222937 0.96

chr5_-_24365703 0.93 ENSDART00000112287
gas2l1
growth arrest-specific 2 like 1
chr7_+_37105966 0.92 ENSDART00000111842
sall1a
spalt-like transcription factor 1a
chr2_-_24947660 0.91 ENSDART00000113356
ENSDART00000163038
crtc1a
CREB regulated transcription coactivator 1a
chr15_+_28269289 0.91 ENSDART00000077736
vtna
vitronectin a
chr1_+_23093475 0.90

chr22_+_35090105 0.89

chr16_+_17481157 0.88 ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr17_-_19606453 0.87 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr23_-_21607811 0.83 ENSDART00000139092
rcc2
regulator of chromosome condensation 2
chr11_-_11689402 0.82

chr20_-_2936289 0.81 ENSDART00000104667
cdk19
cyclin-dependent kinase 19
chr3_-_16077831 0.79 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr21_+_8249235 0.79 ENSDART00000129749
psmb7
proteasome subunit beta 7
chr3_+_23608395 0.77

chr3_+_26015378 0.76

chr16_+_24058139 0.72

chr8_-_14446883 0.71 ENSDART00000057644
lhx4
LIM homeobox 4
chr23_-_20412221 0.70 ENSDART00000132769
CR749762.2
ENSDARG00000093223
chr17_+_45892751 0.69

chr24_-_28813986 0.67 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr6_-_23830912 0.66

chr24_-_25021505 0.64 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr3_+_23621561 0.62 ENSDART00000146636
hoxb2a
homeobox B2a
chr15_+_8791540 0.62 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr24_+_24316486 0.62 ENSDART00000147658
bhlhe22
basic helix-loop-helix family, member e22
chr7_-_32977618 0.60 ENSDART00000052389
itga11a
integrin, alpha 11a
chr9_+_32267297 0.57

chr5_+_19737802 0.53 ENSDART00000153643
ssh1a
slingshot protein phosphatase 1a
chr8_-_18546957 0.53 ENSDART00000123917
ENSDART00000063518
tmem47
transmembrane protein 47
chr3_+_7727322 0.52 ENSDART00000160328
zgc:109949
zgc:109949
chr8_+_40604188 0.51

chr14_+_35890811 0.50 ENSDART00000141766
elovl6
ELOVL fatty acid elongase 6
chr12_+_39496010 0.49

chr10_+_26609369 0.48 ENSDART00000148617
ENSDART00000112956
slc9a6b
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr17_+_23102259 0.44 ENSDART00000178403
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr13_+_23152160 0.44 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr20_+_20772488 0.43 ENSDART00000027758
rtn1b
reticulon 1b
chr2_+_31682629 0.43 ENSDART00000143914
si:ch211-106h4.12
si:ch211-106h4.12
chr11_+_23012136 0.40 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr7_+_21006803 0.40 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr21_-_27301938 0.39 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr6_+_29096734 0.36

chr10_+_36082726 0.35 ENSDART00000165386
hmgb1a
high mobility group box 1a
chr13_+_8272812 0.34 ENSDART00000091097
socs5b
suppressor of cytokine signaling 5b
chr20_-_7303680 0.33 ENSDART00000100060
dsc2l
desmocollin 2 like
chr24_-_28813917 0.33 ENSDART00000042065
ENSDART00000170675
ENSDART00000158668
col11a1a
collagen, type XI, alpha 1a
chr5_+_36332564 0.33 ENSDART00000037879
crx
cone-rod homeobox
chr24_-_32115473 0.32 ENSDART00000168419
rsu1
Ras suppressor protein 1
chr8_-_18547147 0.32 ENSDART00000123917
ENSDART00000063518
tmem47
transmembrane protein 47
chr24_-_14447136 0.32

chr10_+_31358307 0.32 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr25_+_32419062 0.31

chr24_+_24316408 0.29 ENSDART00000147658
bhlhe22
basic helix-loop-helix family, member e22
chr1_-_22466834 0.29 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr4_+_13430131 0.29 ENSDART00000137200
si:dkey-39a18.1
si:dkey-39a18.1
chr2_+_1881022 0.28 ENSDART00000101038
tmie
transmembrane inner ear
chr11_-_3940007 0.28 ENSDART00000045971
pbrm1
polybromo 1
chr21_-_26446246 0.24 ENSDART00000112410
ankhd1
ankyrin repeat and KH domain containing 1
chr12_-_11419332 0.24 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr25_+_19889409 0.23 ENSDART00000178266
ENSDART00000121226
FO704882.1
ENSDARG00000085826
chr7_+_51879116 0.23 ENSDART00000098712
TMEM208
transmembrane protein 208
chr13_-_36495730 0.22 ENSDART00000165629
cdkn3
cyclin-dependent kinase inhibitor 3
chr24_+_24316346 0.20 ENSDART00000147658
bhlhe22
basic helix-loop-helix family, member e22
chr1_-_686007 0.16 ENSDART00000165894
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr8_-_18547116 0.16 ENSDART00000123917
ENSDART00000063518
tmem47
transmembrane protein 47
chr24_-_28814284 0.14 ENSDART00000003503
col11a1a
collagen, type XI, alpha 1a
chr23_-_6793566 0.12 ENSDART00000171714
baz2a
bromodomain adjacent to zinc finger domain, 2A
chr7_+_38540519 0.10 ENSDART00000052322
zgc:110699
zgc:110699
KN149949v1_+_25867 0.08

KN149949v1_+_25953 0.08

chr23_-_31033917 0.06 ENSDART00000142661
osbpl2a
oxysterol binding protein-like 2a
chr10_-_33212897 0.06 ENSDART00000081170
cux1a
cut-like homeobox 1a
chr3_+_35277555 0.06

chr19_+_12525407 0.05 ENSDART00000135706
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr14_+_7626683 0.04 ENSDART00000171657
cxxc5b
CXXC finger protein 5b
chr11_-_27832530 0.04 ENSDART00000172937
BX248318.1
ENSDARG00000104418
chr11_+_13470759 0.01 ENSDART00000011362
arrdc2
arrestin domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0002686 negative regulation of leukocyte migration(GO:0002686) regulation of hematopoietic stem cell migration(GO:2000471)
0.9 2.6 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.6 5.1 GO:0002159 desmosome assembly(GO:0002159)
0.5 2.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.5 7.9 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.5 1.9 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.4 1.3 GO:0002280 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.4 1.2 GO:0032475 otolith formation(GO:0032475)
0.4 1.4 GO:0003210 cardiac atrium formation(GO:0003210)
0.4 1.8 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.3 1.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.3 1.9 GO:2000742 regulation of anterior head development(GO:2000742)
0.3 2.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.3 1.8 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024)
0.3 1.1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.3 1.5 GO:0032371 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.2 1.8 GO:0060827 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.2 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.1 GO:0034650 cortisol metabolic process(GO:0034650)
0.2 3.9 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 1.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 3.6 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 3.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 0.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.6 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 1.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 2.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.1 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.5 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.7 GO:1900153 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.6 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.5 GO:0007548 sex differentiation(GO:0007548)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 3.6 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 2.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.9 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.9 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.4 GO:0009409 response to cold(GO:0009409)
0.0 0.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 7.2 GO:0022610 cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.0 0.3 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.1 GO:0010991 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 5.1 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.1 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.9 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.3 GO:0030315 T-tubule(GO:0030315)
0.1 4.0 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 2.6 GO:0016459 myosin complex(GO:0016459)
0.0 3.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.0 2.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 2.8 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 3.7 GO:0030424 axon(GO:0030424)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.5 4.6 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.4 1.4 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 2.6 GO:0048495 Roundabout binding(GO:0048495)
0.3 3.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 2.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.0 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 9.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 2.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 8.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 15.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.0 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 2.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.6 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation