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Results for hoxc11b

Z-value: 1.03

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Transcription factors associated with hoxc11b

Gene Symbol Gene ID Gene Info
hoxc11b
ENSDARG00000102631 homeobox C11b

Activity profile of hoxc11b motif

Sorted Z-values of hoxc11b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc11b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_45950530 4.41 ENSDART00000060822
afp4
antifreeze protein type IV
chr3_+_26896869 4.27 ENSDART00000065495
emp2
epithelial membrane protein 2
chr23_+_10211543 3.95 ENSDART00000048073
zgc:171775
zgc:171775
chr23_+_39713307 3.57 ENSDART00000109464
g0s2
G0/G1 switch 2
chr16_-_39620777 3.21 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr18_-_15404998 3.17 ENSDART00000031752
rfx4
regulatory factor X, 4
chr24_+_5205878 3.15 ENSDART00000106488
ENSDART00000005901
plod2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr18_+_22617072 3.15 ENSDART00000128965
bcar1
breast cancer anti-estrogen resistance 1
chr14_-_24463906 2.80 ENSDART00000126199
slit3
slit homolog 3 (Drosophila)
chr23_+_25428372 2.67 ENSDART00000147440
fmnl3
formin-like 3
chr9_-_48673183 2.62 ENSDART00000140185
ENSDART00000134185
col28a2a
collagen, type XXVIII, alpha 2a
chr5_-_39910235 2.57 ENSDART00000146237
ENSDART00000163302
fsta
follistatin a
chr6_+_56157608 2.44 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr7_+_35769973 2.41 ENSDART00000168658
irx3a
iroquois homeobox 3a
chr2_+_20748431 2.40 ENSDART00000137848
palmda
palmdelphin a
chr8_-_44305494 2.38 ENSDART00000098520
fzd10
frizzled class receptor 10
chr18_+_26437604 2.36 ENSDART00000060245
ctsh
cathepsin H
chr8_-_38126693 2.35 ENSDART00000112331
adgra2
adhesion G protein-coupled receptor A2
chr18_-_15405161 2.34 ENSDART00000031752
rfx4
regulatory factor X, 4
chr23_+_36023748 2.34

chr18_+_730277 2.33 ENSDART00000159846
prtga
protogenin homolog a (Gallus gallus)
chr14_+_4169846 2.31 ENSDART00000038301
gnpda2
glucosamine-6-phosphate deaminase 2
chr21_+_25199691 2.28 ENSDART00000168140
ENSDART00000112783
tmem45b
transmembrane protein 45B
chr9_+_17298410 2.26 ENSDART00000048548
scel
sciellin
chr2_-_30675594 2.24 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr10_-_10372266 2.19

chr7_-_26035308 2.19 ENSDART00000131906
zgc:77439
zgc:77439
chr6_-_39315024 2.15 ENSDART00000012644
krt4
keratin 4
chr19_+_22478256 2.10 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr23_+_22977031 2.01

chr15_-_25592228 1.79 ENSDART00000157498
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr6_+_35378839 1.79 ENSDART00000102483
ENSDART00000133783
rgs4
regulator of G protein signaling 4
chr1_+_45503061 1.76 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr3_+_61924544 1.75 ENSDART00000090370
noxo1a
NADPH oxidase organizer 1a
chr20_+_51385187 1.74

chr2_+_53253623 1.73 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr9_-_1954910 1.73 ENSDART00000140438
BX322661.1
ENSDARG00000094186
chr25_-_13518274 1.70 ENSDART00000165510
fa2h
fatty acid 2-hydroxylase
chr25_+_19992389 1.69 ENSDART00000143441
tnni4b.2
troponin I4b, tandem duplicate 2
chr15_-_1858350 1.67 ENSDART00000082026
mmp28
matrix metallopeptidase 28
chr17_-_52735250 1.67

chr8_+_47644421 1.66 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr18_+_45893199 1.63 ENSDART00000158246
dvl3b
dishevelled segment polarity protein 3b
chr5_-_40707316 1.63 ENSDART00000161932
npr3
natriuretic peptide receptor 3
chr3_-_19050721 1.63 ENSDART00000131503
rfx1a
regulatory factor X, 1a (influences HLA class II expression)
chr3_+_23563620 1.63 ENSDART00000147022
hoxb7a
homeobox B7a
chr17_-_23707863 1.62 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr3_+_23580269 1.62 ENSDART00000151584
hoxb4a
homeobox B4a
chr17_-_2513630 1.58 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr16_+_21436660 1.55 ENSDART00000145886
osbpl3b
oxysterol binding protein-like 3b
chr4_+_5733160 1.51 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr16_-_33105847 1.49

chr10_-_10906027 1.47 ENSDART00000122657
nrarpa
notch-regulated ankyrin repeat protein a
chr21_-_17259886 1.46 ENSDART00000114877
gfi1b
growth factor independent 1B transcription repressor
chr23_+_7445760 1.45 ENSDART00000012194
gata5
GATA binding protein 5
chr16_-_55320569 1.44 ENSDART00000156368
ENSDARG00000069583
ENSDARG00000069583
chr14_-_31128891 1.44

chr17_+_52736192 1.42 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr23_+_27141681 1.39 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr5_-_41672394 1.39 ENSDART00000164363
si:ch211-207c6.2
si:ch211-207c6.2
chr10_-_22834248 1.32 ENSDART00000079469
pcolcea
procollagen C-endopeptidase enhancer a
chr24_-_16884946 1.31 ENSDART00000171988
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr21_-_3548719 1.30 ENSDART00000137844
atp8b1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr2_-_40170303 1.29 ENSDART00000165602
epha4a
eph receptor A4a
chr14_+_34626233 1.27 ENSDART00000004550
rnf145a
ring finger protein 145a
chr19_-_19290260 1.26

chr20_+_26981663 1.24 ENSDART00000077769
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_+_69383382 1.21 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
KN150230v1_-_36595 1.20

chr6_-_50705420 1.19 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr11_+_42265857 1.17 ENSDART00000039206
rps23
ribosomal protein S23
chr14_+_45895103 1.17

chr12_-_27032151 1.17 ENSDART00000153365
BX001014.2
ENSDARG00000096750
chr1_+_27174549 1.16 ENSDART00000102337
dnajb14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr17_-_37040941 1.16 ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr23_-_7740845 1.15 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr20_+_52740555 1.14 ENSDART00000110777
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr25_+_30701751 1.13

chr6_-_60152693 1.10 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr21_+_10663517 1.09 ENSDART00000074833
rx3
retinal homeobox gene 3
chr4_-_13394059 1.07 ENSDART00000175909
ENSDART00000174861
BX511038.1
ENSDARG00000108089
chr24_+_30386569 1.07 ENSDART00000162555
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr22_-_22696091 1.07

chr13_+_12257610 1.07 ENSDART00000086525
atp10d
ATPase, class V, type 10D
chr17_+_52736535 1.07 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr16_-_21238288 1.07 ENSDART00000139737
cbx3b
chromobox homolog 3b
chr17_-_52735615 1.05

chr13_+_4276783 1.04 ENSDART00000148280
prr18
proline rich 18
chr11_-_18166056 1.03 ENSDART00000155752
sfmbt1
Scm-like with four mbt domains 1
chr23_+_22858531 1.02 ENSDART00000111345
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr7_-_23474701 1.02 ENSDART00000048050
ITGB1BP2
integrin subunit beta 1 binding protein 2
chr5_-_66293492 1.01

chr22_-_10540794 0.99 ENSDART00000140736
si:dkey-42i9.6
si:dkey-42i9.6
chr25_-_22821132 0.98

chr9_-_23346038 0.98 ENSDART00000135461
lypd6b
LY6/PLAUR domain containing 6B
chr12_-_18839556 0.96 ENSDART00000172574
ep300a
E1A binding protein p300 a
chr23_+_24711233 0.95

chr6_-_60152594 0.95 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr10_-_31619761 0.94 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr23_+_35954132 0.91 ENSDART00000103149
hoxc13a
homeobox C13a
chr10_-_42157835 0.90 ENSDART00000141500
ENSDART00000156626
BX005309.1
ENSDARG00000093535
chr5_+_64411584 0.88 ENSDART00000158484
BX001023.2
ENSDARG00000101163
chr5_+_23741791 0.87 ENSDART00000049003
atp6v1aa
ATPase, H+ transporting, lysosomal, V1 subunit Aa
chr4_+_27141061 0.85 ENSDART00000145083
brd1a
bromodomain containing 1a
chr17_+_24428093 0.84 ENSDART00000131417
ugp2b
UDP-glucose pyrophosphorylase 2b
chr19_+_20189224 0.83 ENSDART00000163611
hoxa4a
homeobox A4a
chr19_-_27152063 0.83 ENSDART00000109258
csnk2b
casein kinase 2, beta polypeptide
chr23_-_10906094 0.82

chr19_+_42899678 0.81 ENSDART00000076915
si:dkey-166k12.1
si:dkey-166k12.1
chr4_+_119964 0.81 ENSDART00000177177
ENSDART00000159996
tbk1
TANK-binding kinase 1
chr12_+_10096495 0.79 ENSDART00000152212
ENSDART00000127343
smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr25_+_5567388 0.79

chr17_+_15780370 0.78 ENSDART00000027667
ENSDART00000161637
rragd
ras-related GTP binding D
chr17_+_52736844 0.78 ENSDART00000160507
meis2a
Meis homeobox 2a
chr5_+_19802818 0.76

chr10_+_2559774 0.76 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr25_+_34791665 0.75

chr8_-_18868986 0.75 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr8_+_25984588 0.75

chr21_+_26695270 0.74

chr5_+_52934865 0.74 ENSDART00000161682
BX323994.2
ENSDARG00000100423
chr13_-_24779651 0.73 ENSDART00000077775
kat6b
K(lysine) acetyltransferase 6B
chr19_+_20174462 0.71 ENSDART00000166129
hoxa9a
homeobox A9a
chr19_-_36146250 0.71 ENSDART00000066712
trappc3
trafficking protein particle complex 3
chr6_+_30716955 0.70 ENSDART00000104628
insl5a
insulin-like 5a
chr5_-_70688185 0.67 ENSDART00000108804
brinp1
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr18_+_26437724 0.67 ENSDART00000060245
ctsh
cathepsin H
chr4_+_5246465 0.67 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr11_+_36781811 0.67 ENSDART00000109235
bicd2
bicaudal D homolog 2 (Drosophila)
chr8_-_44305846 0.67 ENSDART00000144497
piwil1
piwi-like RNA-mediated gene silencing 1
chr6_+_4379989 0.66 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr10_-_30016761 0.66 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr1_+_966385 0.65 ENSDART00000051919
n6amt1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr24_-_8592102 0.64 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr25_-_34468195 0.63 ENSDART00000045177
cdk10
cyclin-dependent kinase 10
chr20_+_20887959 0.63

chr23_+_11734349 0.63 ENSDART00000091416
cntn3a.1
contactin 3a, tandem duplicate 1
chr22_-_26307952 0.61

chr24_-_6129575 0.60 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr7_+_60992745 0.60 ENSDART00000083255
adam19a
ADAM metallopeptidase domain 19a
chr15_-_25457193 0.59 ENSDART00000124205
si:dkey-54n8.4
si:dkey-54n8.4
chr4_-_5643440 0.59 ENSDART00000010903
rsph9
radial spoke head 9 homolog
chr11_+_18020191 0.59 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr11_-_24190842 0.57 ENSDART00000103752
dvl1b
dishevelled segment polarity protein 1b
chr7_-_18256512 0.55 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr7_+_31608878 0.55 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr13_-_35908743 0.55 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr24_-_38758093 0.54

chr17_-_18869111 0.54 ENSDART00000080029
ak7b
adenylate kinase 7b
chr5_-_8568715 0.53 ENSDART00000099891
atp5ib
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit Eb
chr3_+_25023544 0.53 ENSDART00000156973
si:ch211-256m1.8
si:ch211-256m1.8
chr12_-_24974450 0.53 ENSDART00000163775
ENSDART00000159167
socs5a
suppressor of cytokine signaling 5a
chr23_+_4544178 0.52 ENSDART00000092389
nup210
nucleoporin 210
chr11_-_18305730 0.51 ENSDART00000155474
fgd5a
FYVE, RhoGEF and PH domain containing 5a
chr10_-_24401876 0.51 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr1_+_32669248 0.50 ENSDART00000133870
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr20_-_16553010 0.50

chr24_-_8592157 0.49 ENSDART00000082351
tfap2a
transcription factor AP-2 alpha
chr3_+_24003840 0.49 ENSDART00000156204
si:ch211-246i5.5
si:ch211-246i5.5
chr2_+_23600656 0.49

chr5_+_58017820 0.47 ENSDART00000083015
ccdc84
coiled-coil domain containing 84
KN150183v1_+_12947 0.46

chr20_-_51454257 0.45 ENSDART00000023064
slc35b2
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr20_-_34767302 0.45 ENSDART00000033325
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr10_+_44853121 0.44 ENSDART00000167952
scarb1
scavenger receptor class B, member 1
chr25_+_15983777 0.44 ENSDART00000165598
ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr18_-_15361133 0.44 ENSDART00000019818
ric8b
RIC8 guanine nucleotide exchange factor B
chr14_+_4169371 0.43 ENSDART00000136665
gnpda2
glucosamine-6-phosphate deaminase 2
chr17_-_9794215 0.40

chr17_+_21270766 0.39

chr3_+_18263447 0.38 ENSDART00000127796
gaa
glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)
chr9_+_33049445 0.38 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr13_+_36459706 0.37 ENSDART00000138940
gmfb
glia maturation factor, beta
chr1_+_51846516 0.36 ENSDART00000074231
cldnd1b
claudin domain containing 1b
chr23_+_44543892 0.35 ENSDART00000097644
ephb4b
eph receptor B4b
chr9_+_33049549 0.35 ENSDART00000121751
si:dkey-145p14.5
si:dkey-145p14.5
chr12_-_20251183 0.35 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr12_+_26930895 0.35 ENSDART00000152975
msl1b
male-specific lethal 1 homolog b (Drosophila)
chr4_+_14658179 0.34 ENSDART00000168152
abcc9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_51658383 0.34 ENSDART00000132638
ENSDARG00000059948
ENSDARG00000059948
chr3_-_39117801 0.33 ENSDART00000102678
nmt1a
N-myristoyltransferase 1a
chr23_+_22858650 0.32 ENSDART00000142085
rerea
arginine-glutamic acid dipeptide (RE) repeats a
chr19_-_15324958 0.32 ENSDART00000055619
phactr4a
phosphatase and actin regulator 4a
chr20_-_34767188 0.32 ENSDART00000033325
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr12_-_10372346 0.31 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr7_+_35770134 0.30 ENSDART00000168658
irx3a
iroquois homeobox 3a
chr16_+_13993746 0.29 ENSDART00000101304
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr24_-_21366493 0.29 ENSDART00000109587
rnf6
ring finger protein (C3H2C3 type) 6
chr6_-_12060971 0.28 ENSDART00000155685
pkp4
plakophilin 4
chr7_+_30874387 0.28 ENSDART00000075407
ENSDART00000169462
fam189a1
family with sequence similarity 189, member A1
chr25_+_7359375 0.28

chr22_-_11618612 0.28 ENSDART00000109596
dpp4
dipeptidyl-peptidase 4
chr2_+_1881022 0.27 ENSDART00000101038
tmie
transmembrane inner ear
chr1_+_33510660 0.27 ENSDART00000147201
slc5a7a
solute carrier family 5 (sodium/choline cotransporter), member 7a
chr6_+_60152913 0.26

chr10_-_25629613 0.26 ENSDART00000131640
tiam1a
T-cell lymphoma invasion and metastasis 1a
chr3_+_27655753 0.25 ENSDART00000086994
nat15
N-acetyltransferase 15 (GCN5-related, putative)
chr3_+_24059652 0.23 ENSDART00000034762
prr15la
proline rich 15-like a
chr10_-_42155790 0.23

chr14_+_45895037 0.22

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.0 3.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.6 3.1 GO:0090527 actin filament reorganization(GO:0090527)
0.6 2.3 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.5 4.3 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.5 2.7 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.4 2.0 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 2.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 1.4 GO:0048618 post-embryonic morphogenesis(GO:0009886) post-embryonic foregut morphogenesis(GO:0048618)
0.4 1.1 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 2.2 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 1.1 GO:0006210 thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 0.7 GO:0035092 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 1.2 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 1.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.2 1.4 GO:0006833 water transport(GO:0006833)
0.2 4.4 GO:0060030 dorsal convergence(GO:0060030)
0.2 2.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 1.3 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.2 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.2 0.6 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 0.6 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 0.5 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 1.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 1.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 1.5 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 2.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 3.6 GO:0043049 otic placode formation(GO:0043049)
0.1 0.3 GO:0070285 pigment cell development(GO:0070285)
0.1 1.8 GO:0014823 response to activity(GO:0014823)
0.1 2.7 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.6 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.6 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.6 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 1.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.8 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 4.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.1 0.7 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.1 2.4 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 0.2 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.3 GO:1900619 neuromuscular synaptic transmission(GO:0007274) acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 0.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.2 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.3 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 3.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.6 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 3.3 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.4 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.3 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 2.3 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.4 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 1.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 2.3 GO:0008544 epidermis development(GO:0008544)
0.0 1.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 2.6 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.9 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 2.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.5 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 2.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.1 1.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 5.8 GO:0005581 collagen trimer(GO:0005581)
0.1 2.1 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 6.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 1.8 GO:0005861 troponin complex(GO:0005861)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.7 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 3.1 GO:0005925 focal adhesion(GO:0005925)
0.0 2.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.6 GO:0030424 axon(GO:0030424)
0.0 9.9 GO:0005576 extracellular region(GO:0005576)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.2 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026) type I transforming growth factor beta receptor binding(GO:0034713)
0.7 2.0 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.5 1.6 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.5 2.7 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.4 2.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.1 GO:0002054 nucleobase binding(GO:0002054)
0.3 1.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 2.6 GO:0048185 activin binding(GO:0048185)
0.3 2.8 GO:0048495 Roundabout binding(GO:0048495)
0.3 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 1.7 GO:0015250 water channel activity(GO:0015250)
0.2 0.5 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 4.0 GO:0004707 MAP kinase activity(GO:0004707)
0.2 0.7 GO:0034584 piRNA binding(GO:0034584)
0.2 3.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 0.6 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.6 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 2.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 4.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.7 GO:0034452 dynactin binding(GO:0034452)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.8 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 2.7 GO:0045296 cadherin binding(GO:0045296)
0.0 5.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 3.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)
0.0 15.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 1.7 GO:0060090 binding, bridging(GO:0060090)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.8 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 9.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases