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Results for hoxc12a+hoxc12b

Z-value: 0.95

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Transcription factors associated with hoxc12a+hoxc12b

Gene Symbol Gene ID Gene Info
hoxc12a
ENSDARG00000070352 homeobox C12a
hoxc12b
ENSDARG00000103133 homeobox C12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc12adr10_dc_chr23_+_35964754_359648170.674.3e-03Click!
hoxc12bdr10_dc_chr11_-_2133416_21334530.674.4e-03Click!

Activity profile of hoxc12a+hoxc12b motif

Sorted Z-values of hoxc12a+hoxc12b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc12a+hoxc12b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr23_-_35997065 3.52 ENSDART00000153910
BX005254.4
ENSDARG00000097150
chr7_-_23601966 2.50 ENSDART00000101408
zgc:162171
zgc:162171
chr3_+_23580269 2.42 ENSDART00000151584
hoxb4a
homeobox B4a
chr23_+_36010592 2.39 ENSDART00000137507
hoxc3a
homeo box C3a
chr23_+_35988395 2.33 ENSDART00000154825
hoxc3a
homeo box C3a
chr12_+_2642541 2.26 ENSDART00000093113
antxr1c
anthrax toxin receptor 1c
chr9_-_39195468 2.12 ENSDART00000014207
myl1
myosin, light chain 1, alkali; skeletal, fast
chr15_-_14616083 2.06 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr3_-_23444371 1.96 ENSDART00000087726
igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr17_-_23707863 1.95 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr11_-_2107054 1.92 ENSDART00000173031
hoxc6b
homeobox C6b
chr3_-_6078015 1.87 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr14_-_36523075 1.84 ENSDART00000109293
rnf130
ring finger protein 130
chr19_+_20181908 1.77 ENSDART00000158987
hoxa4a
homeobox A4a
chr12_-_10001043 1.73 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr1_+_30215209 1.71 ENSDART00000164520
itga6b
integrin, alpha 6b
chr12_-_26760324 1.70 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr23_+_35996779 1.68 ENSDART00000127384
hoxc9a
homeobox C9a
chr24_-_16884946 1.63 ENSDART00000171988
ptgdsb.2
prostaglandin D2 synthase b, tandem duplicate 2
chr3_+_23577103 1.57 ENSDART00000025449
hoxb5a
homeobox B5a
chr2_-_10555152 1.54 ENSDART00000150166
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr12_+_27038210 1.54 ENSDART00000076161
hoxb5b
homeobox B5b
chr24_+_21395671 1.52 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr12_+_40919018 1.52 ENSDART00000176047
BX072562.1
ENSDARG00000108020
chr21_+_20678383 1.52 ENSDART00000015224
gadd45gb.1
growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1
chr16_+_21104310 1.49 ENSDART00000046766
hoxa10b
homeobox A10b
chr23_+_35988426 1.48 ENSDART00000154825
hoxc3a
homeo box C3a
chr19_+_5399813 1.44 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr3_-_23558171 1.44

chr9_+_44233139 1.42 ENSDART00000162406
itga4
integrin alpha 4
chr25_-_17906512 1.41 ENSDART00000149696
cep290
centrosomal protein 290
chr6_+_10630329 1.39 ENSDART00000174807
BX546447.1
ENSDARG00000108699
chr23_-_28099284 1.38 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr4_-_13996902 1.35 ENSDART00000147955
prickle1b
prickle homolog 1b
chr15_-_18159904 1.35 ENSDART00000170874
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr24_-_31285981 1.34 ENSDART00000164155
alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr21_+_13031158 1.31 ENSDART00000081426
odf2a
outer dense fiber of sperm tails 2a
chr3_-_23580055 1.27

chr1_-_33880029 1.24 ENSDART00000004361
klf5a
Kruppel-like factor 5a
chr10_-_33678206 1.16 ENSDART00000128049
hunk
hormonally up-regulated Neu-associated kinase
chr12_+_27038298 1.10 ENSDART00000076161
hoxb5b
homeobox B5b
chr19_+_5399877 1.07 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr19_+_20189224 1.01 ENSDART00000163611
hoxa4a
homeobox A4a
chr11_-_35788900 1.00 ENSDART00000025033
gpx1a
glutathione peroxidase 1a
chr20_+_48971948 1.00 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr7_-_18256512 1.00 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr14_-_27754549 0.99 ENSDART00000135337
zgc:64189
zgc:64189
chr3_+_37645350 0.97 ENSDART00000134524
rps11
ribosomal protein S11
chr10_+_2559774 0.96 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr23_-_28099391 0.96 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr3_+_23561215 0.92 ENSDART00000078453
hoxb7a
homeobox B7a
chr22_-_29788268 0.89

chr6_-_31160132 0.89 ENSDART00000153592
CR847887.1
ENSDARG00000097226
chr8_+_3391493 0.88 ENSDART00000085993
pxnb
paxillin b
chr21_-_18981828 0.85 ENSDART00000080256
nefma
neurofilament, medium polypeptide a
chr1_-_22144014 0.84 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr3_+_23580216 0.84 ENSDART00000151584
hoxb4a
homeobox B4a
chr14_+_30568242 0.83

chr21_+_13764828 0.81 ENSDART00000171306
stxbp1a
syntaxin binding protein 1a
chr7_+_20700070 0.80

chr23_-_28099359 0.79 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr16_+_5284778 0.79 ENSDART00000156685
ENSDART00000156765
soga3a
soga3a
SOGA family member 3a
SOGA family member 3a
chr23_+_25224499 0.77

chr9_+_55778669 0.76

chr3_+_59560881 0.71 ENSDART00000084738
ppp1r27a
protein phosphatase 1, regulatory subunit 27a
KN150230v1_-_36595 0.70

chr3_-_45237479 0.65 ENSDART00000160923
si:ch73-167f10.1
si:ch73-167f10.1
chr12_-_22438379 0.65 ENSDART00000177715
CR925753.1
ENSDARG00000108493
chr23_+_35988366 0.64 ENSDART00000154825
hoxc3a
homeo box C3a
chr15_+_29183251 0.63 ENSDART00000153609
capns1b
calpain, small subunit 1 b
chr23_-_28099235 0.62 ENSDART00000024283
sp5l
Sp5 transcription factor-like
chr7_+_28896401 0.62 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr6_+_4091384 0.62 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr12_-_48562929 0.61 ENSDART00000063438
CABZ01079984.1
uncharacterized protein C7orf62 homolog
chr2_-_55673404 0.60 ENSDART00000158147
calr3b
calreticulin 3b
chr3_+_23561306 0.60 ENSDART00000078453
hoxb7a
homeobox B7a
chr14_+_35351559 0.58 ENSDART00000074685
glrbb
glycine receptor, beta b
chr6_-_28231995 0.56 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr17_-_51110171 0.55 ENSDART00000088185
paplna
papilin a, proteoglycan-like sulfated glycoprotein
chr3_+_23561502 0.54 ENSDART00000078453
hoxb7a
homeobox B7a
chr25_-_17906739 0.50 ENSDART00000149696
cep290
centrosomal protein 290
chr11_+_14373731 0.49 ENSDART00000161879
BX571942.1
ENSDARG00000099220
chr14_+_31682159 0.47 ENSDART00000105760
zic6
zic family member 6
chr25_+_17906724 0.46

chr6_-_53333648 0.45 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr8_+_48888672 0.44

chr15_-_19508230 0.44 ENSDART00000114936
esamb
endothelial cell adhesion molecule b
chr22_+_10411257 0.44 ENSDART00000064805
cenpp
centromere protein P
chr13_+_33138144 0.43 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr22_-_9706237 0.40 ENSDART00000152919
si:dkey-286j17.4
si:dkey-286j17.4
chr6_+_4379989 0.39 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr15_-_19314712 0.37 ENSDART00000092705
igsf9ba
immunoglobulin superfamily, member 9Ba
KN150222v1_+_74557 0.36

chr16_+_38709412 0.36 ENSDART00000023238
emc2
ER membrane protein complex subunit 2
chr20_+_32646617 0.34

chr9_-_3675527 0.33

chr1_-_7417472 0.32 ENSDART00000161938
ENSDART00000163307
si:dkeyp-9d4.3
si:dkeyp-9d4.3
chr20_+_36098607 0.32 ENSDART00000021456
opn5
opsin 5
chr11_+_6648811 0.31 ENSDART00000172061
CR381534.1
ENSDARG00000098564
chr16_-_6304533 0.31 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr2_+_24851910 0.31 ENSDART00000133109
rps28
ribosomal protein S28
chr2_-_6351592 0.30

chr11_-_27832530 0.29 ENSDART00000172937
BX248318.1
ENSDARG00000104418
chr2_+_54966412 0.27 ENSDART00000074270
ankrd12
ankyrin repeat domain 12
chr13_-_44601523 0.26 ENSDART00000074761
zfand3
zinc finger, AN1-type domain 3
chr21_+_13764917 0.26 ENSDART00000015629
stxbp1a
syntaxin binding protein 1a
chr2_-_39793399 0.25 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr19_+_20189194 0.25 ENSDART00000163611
hoxa4a
homeobox A4a
chr16_+_10538946 0.25 ENSDART00000173132
vars
valyl-tRNA synthetase
chr17_-_32913287 0.23 ENSDART00000077476
prox1a
prospero homeobox 1a
chr25_+_17906515 0.21

chr3_+_24059652 0.20 ENSDART00000034762
prr15la
proline rich 15-like a
chr1_-_45972732 0.20 ENSDART00000134450
ebpl
emopamil binding protein-like
chr2_-_37891963 0.19 ENSDART00000039386
zgc:66427
zgc:66427
chr9_+_20672966 0.19 ENSDART00000145111
parp4
poly (ADP-ribose) polymerase family, member 4
chr6_+_4091251 0.19 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr18_-_21759607 0.16 ENSDART00000079253
pskh1
protein serine kinase H1
chr11_+_6138968 0.15 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr16_-_10425382 0.15 ENSDART00000104025
ENSDART00000178832
flot1b
flotillin 1b
chr1_-_43936717 0.14 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr2_-_19181629 0.13 ENSDART00000165782
pbx1a
pre-B-cell leukemia homeobox 1a
chr19_-_45499458 0.13

chr5_-_28888704 0.10

chr25_+_3168376 0.09 ENSDART00000030683
tmpob
thymopoietin b
chr23_+_8862155 0.05 ENSDART00000132992
sox18
SRY (sex determining region Y)-box 18
chr19_-_18671902 0.05

chr5_-_64637049 0.05 ENSDART00000164649
col27a1b
collagen, type XXVII, alpha 1b
chr15_+_27454643 0.04 ENSDART00000164887
ENSDART00000018603
tbx4
T-box 4
chr21_+_13030816 0.04 ENSDART00000179221
odf2a
outer dense fiber of sperm tails 2a
chr5_+_31889674 0.03 ENSDART00000165417
ndor1
NADPH dependent diflavin oxidoreductase 1
chr13_-_9543393 0.02 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr16_-_47491350 0.02 ENSDART00000149723
sept7b
septin 7b
chr23_+_36020128 0.02 ENSDART00000103134
ENSDART00000139319
hoxc5a
homeobox C5a
chr7_+_27626968 0.02 ENSDART00000178912
tub
tubby bipartite transcription factor
chr1_-_43936611 0.01 ENSDART00000170912
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr7_+_20699940 0.01 ENSDART00000062003
efnb3b
ephrin-B3b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.6 2.3 GO:1901998 toxin transport(GO:1901998)
0.4 1.7 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.2 1.9 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 2.6 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 2.5 GO:0032438 melanosome organization(GO:0032438)
0.1 1.4 GO:0021754 facial nucleus development(GO:0021754)
0.1 1.5 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 1.7 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 3.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 1.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.1 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.3 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 0.2 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.4 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.3 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.3 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.0 GO:0030878 thyroid gland development(GO:0030878)
0.1 18.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.1 0.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 3.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0048885 neuromast deposition(GO:0048885)
0.0 0.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 2.0 GO:0051028 mRNA transport(GO:0051028)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 1.2 GO:0048565 digestive tract development(GO:0048565)
0.0 0.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.4 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 1.9 GO:0034451 centriolar satellite(GO:0034451)
0.2 0.8 GO:0005883 neurofilament(GO:0005883)
0.1 1.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 3.1 GO:0008305 integrin complex(GO:0008305)
0.1 0.3 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 1.4 GO:0045180 basal cortex(GO:0045180)
0.1 2.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.3 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.1 GO:0030141 secretory granule(GO:0030141)
0.0 1.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)
0.0 2.1 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.6 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 31.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 2.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.0 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.3 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)