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Results for hoxc13a

Z-value: 1.73

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Transcription factors associated with hoxc13a

Gene Symbol Gene ID Gene Info
hoxc13a
ENSDARG00000070353 homeobox C13a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc13adr10_dc_chr23_+_35954132_359541800.702.3e-03Click!

Activity profile of hoxc13a motif

Sorted Z-values of hoxc13a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc13a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr22_+_30234718 6.71 ENSDART00000172496
add3a
adducin 3 (gamma) a
chr14_+_23917724 5.74 ENSDART00000138082
ENSDART00000079215
stc2a
stanniocalcin 2a
chr14_-_2008649 5.29 ENSDART00000161817
pcdh2g16
protocadherin 2 gamma 16
chr25_+_30699938 5.17 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr9_-_1964814 4.98 ENSDART00000082354
hoxd9a
homeobox D9a
chr22_-_3661536 4.36 ENSDART00000153634
FP565432.1
ENSDARG00000097145
chr7_+_23843682 4.17 ENSDART00000173899
mrpl52
mitochondrial ribosomal protein L52
chr9_-_1958795 4.01 ENSDART00000138730
hoxd3a
homeobox D3a
chr4_-_16556116 3.90 ENSDART00000033188
btg1
B-cell translocation gene 1, anti-proliferative
chr7_-_23601966 3.70 ENSDART00000101408
zgc:162171
zgc:162171
chr2_+_21067708 3.64 ENSDART00000148400
ENSDART00000021168
rxrga
retinoid x receptor, gamma a
chr1_-_23765358 3.60

chr23_-_29138952 3.40 ENSDART00000002812
casz1
castor zinc finger 1
chr6_+_10630329 3.32 ENSDART00000174807
BX546447.1
ENSDARG00000108699
chr14_+_36156947 3.23

chr6_-_23193752 3.22 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr2_+_57136624 3.13 ENSDART00000159912
ENSDARG00000105208
ENSDARG00000105208
chr22_+_12327849 3.06 ENSDART00000178678
FO704572.1
ENSDARG00000106890
chr19_+_20181908 3.02 ENSDART00000158987
hoxa4a
homeobox A4a
chr8_-_28415750 2.94 ENSDART00000062702
cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr12_-_22438379 2.93 ENSDART00000177715
CR925753.1
ENSDARG00000108493
chr22_-_11712371 2.87

chr19_-_47366517 2.84 ENSDART00000043713
angpt1
angiopoietin 1
chr19_+_20183210 2.65 ENSDART00000164968
hoxa4a
homeobox A4a
chr3_+_23561215 2.65 ENSDART00000078453
hoxb7a
homeobox B7a
chr23_+_28656263 2.59 ENSDART00000020296
nadl1.2
neural adhesion molecule L1.2
chr12_-_10001043 2.52 ENSDART00000152250
ngfrb
nerve growth factor receptor b
chr14_-_5239605 2.51 ENSDART00000054877
fgf24
fibroblast growth factor 24
chr4_+_5124186 2.46 ENSDART00000127874
ccnd2b
cyclin D2, b
chr11_+_43924640 2.43 ENSDART00000179206
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr22_-_16971799 2.42 ENSDART00000090242
nfia
nuclear factor I/A
chr14_+_30568242 2.25

chr6_-_13000193 2.22

chr15_-_25582891 2.20

chr3_+_28871566 1.97

chr25_+_34546629 1.92 ENSDART00000133379
hist2h3c
histone cluster 2, H3c
chr22_-_16971035 1.88 ENSDART00000090237
nfia
nuclear factor I/A
chr22_-_29788268 1.88

chr13_-_24316940 1.86 ENSDART00000127741
slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr22_-_16971180 1.77 ENSDART00000090237
nfia
nuclear factor I/A
chr3_+_23561502 1.76 ENSDART00000078453
hoxb7a
homeobox B7a
chr25_-_15117843 1.70 ENSDART00000031499
wt1a
wilms tumor 1a
chr3_+_23561306 1.68 ENSDART00000078453
hoxb7a
homeobox B7a
chr17_-_31204651 1.66 ENSDART00000137834
pcmtl
l-isoaspartyl protein carboxyl methyltransferase, like
chr20_+_53310252 1.65 ENSDART00000175125
CABZ01089116.1
ENSDARG00000106770
chr20_+_32646617 1.63

chr5_-_34393017 1.53 ENSDART00000134516
btf3
basic transcription factor 3
chr25_-_20994084 1.44 ENSDART00000154765
prr5a
proline rich 5a (renal)
chr6_-_40101104 1.41 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr1_+_18272833 1.41 ENSDART00000132379
limch1a
LIM and calponin homology domains 1a
chr11_-_3339651 1.38

chr24_-_6129575 1.33 ENSDART00000021609
gad2
glutamate decarboxylase 2
chr11_+_14373731 1.32 ENSDART00000161879
BX571942.1
ENSDARG00000099220
chr22_+_24188575 1.32 ENSDART00000162227
glrx2
glutaredoxin 2
chr15_+_16451044 1.24 ENSDART00000101789
flot2b
flotillin 2b
chr11_+_6648811 1.22 ENSDART00000172061
CR381534.1
ENSDARG00000098564
chr7_-_6331698 1.16 ENSDART00000166041
FP325123.2
Histone H3.2
chr6_-_23193873 1.14 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr21_-_21111366 1.11

chr19_+_20617339 1.08 ENSDART00000133633
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr10_+_42761097 0.96 ENSDART00000075259
fgfr1b
fibroblast growth factor receptor 1b
chr9_-_33940350 0.92 ENSDART00000149383
ndp
Norrie disease (pseudoglioma)
chr9_+_1964320 0.92

chr25_-_3766929 0.91 ENSDART00000043172
tmem258
transmembrane protein 258
chr19_-_36009321 0.90 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr7_+_54336324 0.89 ENSDART00000168474
fgf3
fibroblast growth factor 3
chr10_+_37983342 0.89 ENSDART00000172548
bhlha9
basic helix-loop-helix family, member a9
chr7_-_26246473 0.86 ENSDART00000140694
eif4a1a
eukaryotic translation initiation factor 4A1A
chr16_-_36090863 0.85

chr1_+_966385 0.82 ENSDART00000051919
n6amt1
N-6 adenine-specific DNA methyltransferase 1 (putative)
chr2_-_39793399 0.82 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr8_-_24788837 0.80 ENSDART00000126220
alx3
ALX homeobox 3
chr20_+_36098607 0.76 ENSDART00000021456
opn5
opsin 5
chr13_+_2213363 0.75 ENSDART00000019989
ENSDART00000165305
fbxo9
F-box protein 9
chr5_-_18510716 0.71 ENSDART00000002624
ENSDART00000110553
ranbp1
RAN binding protein 1
chr13_-_44601523 0.66 ENSDART00000074761
zfand3
zinc finger, AN1-type domain 3
chr10_+_24721186 0.65 ENSDART00000144710
tpte
transmembrane phosphatase with tensin homology
chr24_-_28150352 0.64 ENSDART00000145290
bcl2a
B-cell CLL/lymphoma 2a
chr25_+_35779830 0.60 ENSDART00000073405
zgc:173552
zgc:173552
chr25_-_20993989 0.55

chr16_+_22702982 0.55 ENSDART00000041625
chrnb2b
cholinergic receptor, nicotinic, beta 2b
chr9_-_33975936 0.55 ENSDART00000140779
fundc1
FUN14 domain containing 1
chr21_+_17509116 0.51

chr2_+_38165187 0.45 ENSDART00000135307
sall2
spalt-like transcription factor 2
chr11_+_6138968 0.45 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr7_+_5783441 0.41 ENSDART00000167099
CU459186.5
Histone H3.2
chr13_-_25643419 0.33 ENSDART00000145640
pdlim1
PDZ and LIM domain 1 (elfin)
chr22_+_24188148 0.33 ENSDART00000167996
glrx2
glutaredoxin 2
chr14_+_29933552 0.33

chr13_+_24453943 0.33 ENSDART00000057599
fuom
fucose mutarotase
chr9_+_41910191 0.33

chr17_-_14697094 0.32 ENSDART00000154281
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr12_+_6161471 0.32 ENSDART00000163828
BX248126.1
ENSDARG00000096552
chr18_+_14665460 0.24 ENSDART00000133834
vps9d1
VPS9 domain containing 1
chr17_+_13088982 0.22 ENSDART00000012670
pnn
pinin, desmosome associated protein
chr15_+_27454643 0.20 ENSDART00000164887
ENSDART00000018603
tbx4
T-box 4
chr3_+_33309011 0.17 ENSDART00000164322
gtpbp1
GTP binding protein 1
chr25_+_3168376 0.16 ENSDART00000030683
tmpob
thymopoietin b
chr2_-_55971357 0.14 ENSDART00000154701
ENSDART00000154107
si:ch211-178n15.1
si:ch211-178n15.1
chr7_+_5854890 0.10 ENSDART00000173105
si:dkey-23a13.21
si:dkey-23a13.21
chr25_-_35779675 0.10

chr13_-_9543393 0.07 ENSDART00000041609
tm9sf3
transmembrane 9 superfamily member 3
chr23_+_36020128 0.06 ENSDART00000103134
ENSDART00000139319
hoxc5a
homeobox C5a
chr7_+_54336245 0.05 ENSDART00000168474
fgf3
fibroblast growth factor 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.4 1.7 GO:0072314 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 1.3 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.3 2.5 GO:0048608 gonad development(GO:0008406) negative regulation of endodermal cell fate specification(GO:0042664) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.2 2.9 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.2 6.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 0.9 GO:0021703 locus ceruleus development(GO:0021703)
0.2 3.7 GO:0032438 melanosome organization(GO:0032438)
0.2 0.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 3.6 GO:0032526 response to retinoic acid(GO:0032526)
0.2 5.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 2.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.2 0.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 2.5 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 1.0 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.7 GO:0046607 mitotic centrosome separation(GO:0007100) positive regulation of centrosome cycle(GO:0046607) centrosome separation(GO:0051299)
0.1 0.4 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 1.6 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.1 1.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 2.5 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 15.4 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 5.7 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 5.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.9 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 4.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.7 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 6.1 GO:0006260 DNA replication(GO:0006260)
0.0 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.9 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.3 1.0 GO:0016460 myosin II complex(GO:0016460)
0.2 5.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.7 GO:0016600 flotillin complex(GO:0016600)
0.1 6.7 GO:0014069 postsynaptic density(GO:0014069)
0.1 3.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 4.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 11.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.9 GO:0016607 nuclear speck(GO:0016607)
0.0 2.5 GO:0009986 cell surface(GO:0009986)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0031965 nuclear membrane(GO:0031965)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.7 3.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 2.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.4 1.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.3 1.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 2.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 1.0 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.2 0.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 2.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.1 0.8 GO:0016918 retinal binding(GO:0016918)
0.1 5.7 GO:0005179 hormone activity(GO:0005179)
0.1 1.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 4.4 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 31.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 6.6 GO:0051015 actin filament binding(GO:0051015)
0.0 4.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.9 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 2.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation