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Results for hoxc9a

Z-value: 0.84

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Transcription factors associated with hoxc9a

Gene Symbol Gene ID Gene Info
hoxc9a
ENSDARG00000092809 homeobox C9a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc9adr10_dc_chr23_+_35996491_359965400.862.2e-05Click!

Activity profile of hoxc9a motif

Sorted Z-values of hoxc9a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc9a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_55022668 3.00 ENSDART00000158845
mybphb
myosin binding protein Hb
chr3_-_60973097 2.94 ENSDART00000055062
pvalb1
parvalbumin 1
chr5_-_50972677 2.76 ENSDART00000134606
otpb
orthopedia homeobox b
chr9_-_1954910 2.70 ENSDART00000140438
BX322661.1
ENSDARG00000094186
chr8_+_47644421 2.66 ENSDART00000139096
si:ch211-251b21.1
si:ch211-251b21.1
chr2_-_36058327 1.95 ENSDART00000003550
nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr8_+_15968469 1.94 ENSDART00000134787
elavl4
ELAV like neuron-specific RNA binding protein 4
chr19_+_20183210 1.92 ENSDART00000164968
hoxa4a
homeobox A4a
chr11_+_15905877 1.82 ENSDART00000111284
agtrap
angiotensin II receptor-associated protein
chr10_+_10830549 1.80 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr20_-_39003917 1.76

chr5_-_50972592 1.76 ENSDART00000134606
otpb
orthopedia homeobox b
chr3_+_33168814 1.73 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr10_-_10374032 1.68 ENSDART00000134929
BX323065.1
ENSDARG00000095365
chr22_-_21021645 1.60 ENSDART00000133982
ssbp4
single stranded DNA binding protein 4
chr3_-_6078015 1.55 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr21_-_1716495 1.44 ENSDART00000151049
onecut2
one cut homeobox 2
chr19_-_39048324 1.36 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr19_+_20202737 1.34 ENSDART00000164677
hoxa4a
homeobox A4a
chr17_+_32390603 1.34 ENSDART00000156051
dhx32b
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr20_-_39003972 1.32

chr19_+_20181908 1.31 ENSDART00000158987
hoxa4a
homeobox A4a
chr8_+_6533379 1.26 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr19_+_43414160 1.26 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr5_+_15880920 1.23 ENSDART00000168643
CABZ01088700.1
ENSDARG00000101452
chr3_-_34363698 1.20

chr13_+_14873339 1.19 ENSDART00000057810
emx1
empty spiracles homeobox 1
KN150001v1_+_14939 1.15

chr7_+_31608828 1.08 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr3_+_40667131 1.01 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr25_+_2933235 0.98 ENSDART00000029580
fth1b
ferritin, heavy polypeptide 1b
KN150207v1_-_1208 0.97 ENSDART00000171112
CABZ01112575.1
ENSDARG00000099354
chr9_-_40212864 0.95 ENSDART00000166918
IKZF2
IKAROS family zinc finger 2
chr13_-_43466076 0.95 ENSDART00000172636
ENSDART00000084416
ablim1a
actin binding LIM protein 1a
chr8_+_39525254 0.93

chr21_+_13063614 0.92

chr4_+_10016118 0.91 ENSDART00000144175
ccdc136b
coiled-coil domain containing 136b
chr2_-_41873625 0.87 ENSDART00000155577
ENSDARG00000056490
ENSDARG00000056490
chr23_-_24240728 0.86 ENSDART00000113598
arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr7_-_68417190 0.81

chr10_+_13042496 0.81 ENSDART00000158919
lpar1
lysophosphatidic acid receptor 1
chr5_-_22847399 0.80 ENSDART00000169258
nlgn3b
neuroligin 3b
chr9_-_40212643 0.80 ENSDART00000166918
IKZF2
IKAROS family zinc finger 2
chr9_-_3700395 0.78 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr15_-_16075172 0.78

chr3_-_37558102 0.73 ENSDART00000151810
gpatch8
G patch domain containing 8
chr23_-_4175790 0.73 ENSDART00000109807
ENSDARG00000076299
ENSDARG00000076299
chr19_+_27895343 0.70 ENSDART00000049368
atat1
alpha tubulin acetyltransferase 1
chr23_+_35980812 0.68

chr10_+_26609369 0.68 ENSDART00000148617
ENSDART00000112956
slc9a6b
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6b
chr21_-_27301938 0.67 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr11_+_18710724 0.63 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr15_-_510285 0.62 ENSDART00000058993
psph
phosphoserine phosphatase
chr1_-_22466834 0.60 ENSDART00000144208
adgrl3.1
adhesion G protein-coupled receptor L3.1
chr19_-_39048402 0.58 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr17_-_19606453 0.57 ENSDART00000011432
reep3a
receptor accessory protein 3a
chr12_-_16331781 0.55 ENSDART00000152133
hectd2
HECT domain containing 2
chr9_-_40213039 0.51 ENSDART00000166918
IKZF2
IKAROS family zinc finger 2
chr22_-_21021866 0.50 ENSDART00000133982
ssbp4
single stranded DNA binding protein 4
chr12_+_27122352 0.50 ENSDART00000133048
nbr1a
neighbor of brca1 gene 1a
chr3_+_23608395 0.46

chr15_-_14439483 0.45 ENSDART00000160675
dpf1
D4, zinc and double PHD fingers family 1
chr23_-_24240798 0.45 ENSDART00000135173
CR925709.1
ENSDARG00000092130
chr1_+_33510660 0.44 ENSDART00000147201
slc5a7a
solute carrier family 5 (sodium/choline cotransporter), member 7a
chr5_-_64637049 0.43 ENSDART00000164649
col27a1b
collagen, type XXVII, alpha 1b
chr7_-_26137243 0.43 ENSDART00000111494
gal3st4
galactose-3-O-sulfotransferase 4
chr19_-_31378033 0.42

chr18_+_13589341 0.41 ENSDART00000169552
cdh13
cadherin 13, H-cadherin (heart)
chr12_+_16391933 0.34 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr22_+_35113233 0.33 ENSDART00000123066
srfa
serum response factor a
KN150001v1_+_15017 0.33

chr15_+_8791540 0.32 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr24_-_32115473 0.32 ENSDART00000168419
rsu1
Ras suppressor protein 1
chr9_-_40213104 0.31 ENSDART00000166918
IKZF2
IKAROS family zinc finger 2
chr2_+_1881022 0.31 ENSDART00000101038
tmie
transmembrane inner ear
chr15_+_29241472 0.29

chr9_+_492585 0.28 ENSDART00000112635
ENSDARG00000078172
ENSDARG00000078172
chr25_+_32419062 0.28

chr16_+_42161483 0.26

chr17_+_51173489 0.23 ENSDART00000063738
eipr1
EARP complex and GARP complex interacting protein 1
chr5_-_62187774 0.22

chr17_-_51173358 0.20 ENSDART00000169050
trappc12
trafficking protein particle complex 12
chr9_+_44921233 0.20 ENSDART00000145271
nckap1
NCK-associated protein 1
chr7_+_30779987 0.20 ENSDART00000148347
tjp1a
tight junction protein 1a
chr14_+_11457009 0.19 ENSDART00000110004
frmpd3
FERM and PDZ domain containing 3
chr23_+_8862155 0.18 ENSDART00000132992
sox18
SRY (sex determining region Y)-box 18
chr3_+_40667088 0.17 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr1_-_686007 0.11 ENSDART00000165894
adamts1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_+_1964320 0.11

chr21_-_11877044 0.08 ENSDART00000145194
nop56
NOP56 ribonucleoprotein homolog
chr14_-_25645760 0.07 ENSDART00000141916
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr11_-_16261123 0.06 ENSDART00000115085
lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr4_-_18646081 0.04 ENSDART00000125361
pparaa
peroxisome proliferator-activated receptor alpha a
chr16_+_50489655 0.03

chr24_-_21740552 0.02

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 GO:0021767 mammillary body development(GO:0021767)
0.3 1.1 GO:0003210 cardiac atrium formation(GO:0003210)
0.3 0.8 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.2 1.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.2 GO:0035777 pronephric distal tubule development(GO:0035777)
0.2 1.9 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.7 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.7 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274) acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1 1.8 GO:0008217 regulation of blood pressure(GO:0008217)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.3 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.9 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.4 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.3 GO:0046958 learning(GO:0007612) nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 1.0 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 4.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 2.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.8 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 1.3 GO:0001947 heart looping(GO:0001947)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.4 GO:0043204 perikaryon(GO:0043204)
0.1 0.6 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.6 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 2.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.0 GO:0004322 ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.7 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions