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Results for hoxd10a

Z-value: 0.39

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Transcription factors associated with hoxd10a

Gene Symbol Gene ID Gene Info
hoxd10a
ENSDARG00000057859 homeobox D10a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd10adr10_dc_chr9_-_1969197_1969282-0.611.2e-02Click!

Activity profile of hoxd10a motif

Sorted Z-values of hoxd10a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd10a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_2373601 0.77 ENSDART00000113774
si:ch211-188c16.1
si:ch211-188c16.1
chr19_+_14132374 0.61 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr19_+_14132473 0.55 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr8_-_28359022 0.48 ENSDART00000062693
ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr17_+_31605159 0.48 ENSDART00000157148
cinp
cyclin-dependent kinase 2 interacting protein
chr9_-_3548174 0.47 ENSDART00000145043
ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr25_+_18339864 0.47 ENSDART00000056180
cep41
centrosomal protein 41
chr16_-_42236126 0.46 ENSDART00000076030
fbl
fibrillarin
chr21_+_21242470 0.45 ENSDART00000148346
itpkca
inositol-trisphosphate 3-kinase Ca
chr12_+_30673985 0.45 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr5_+_9579430 0.43 ENSDART00000109236
ENSDARG00000075416
ENSDARG00000075416
chr6_-_39634534 0.43 ENSDART00000077839
atf7b
activating transcription factor 7b
chr6_-_25065823 0.42 ENSDART00000167259
znf326
zinc finger protein 326
chr6_-_25065745 0.37 ENSDART00000165170
znf326
zinc finger protein 326
chr15_-_5913264 0.35 ENSDART00000155156
ENSDART00000155971
si:ch73-281n10.2
si:ch73-281n10.2
chr16_+_17857068 0.35 ENSDART00000149408
them4
thioesterase superfamily member 4
chr22_-_11024649 0.34 ENSDART00000105823
ENSDART00000159995
insrb
insulin receptor b
chr9_-_3548211 0.33 ENSDART00000145043
ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr6_-_39524075 0.33 ENSDART00000065038
atf1
activating transcription factor 1
chr25_-_3091345 0.32 ENSDART00000032390
gtf2h1
general transcription factor IIH, polypeptide 1
chr5_+_30386444 0.32 ENSDART00000005893
ube2g1a
ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast)
chr14_+_44343015 0.30 ENSDART00000079866
slc30a9
solute carrier family 30 (zinc transporter), member 9
chr7_-_18624798 0.30 ENSDART00000113593
mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr5_-_35997345 0.30 ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr11_+_30005716 0.30 ENSDART00000167618
CR790368.1
ENSDARG00000100936
chr13_+_28481835 0.30 ENSDART00000077383
borcs7
BLOC-1 related complex subunit 7
chr6_-_39634666 0.28 ENSDART00000077839
atf7b
activating transcription factor 7b
chr23_-_41367783 0.28

chr11_-_38856849 0.28 ENSDART00000113185
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr22_-_22277418 0.28 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr3_-_15346427 0.28 ENSDART00000144369
sgf29
SAGA complex associated factor 29
chr3_-_26060787 0.26 ENSDART00000113843
ypel3
yippee-like 3
chr17_+_20231630 0.26 ENSDART00000155584
BX005375.1
ENSDARG00000097982
chr3_-_54414615 0.26 ENSDART00000053106
s1pr2
sphingosine-1-phosphate receptor 2
chr18_-_199009 0.26

chr25_+_18339837 0.23 ENSDART00000178154
cep41
centrosomal protein 41
chr2_+_21698414 0.23 ENSDART00000171397
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr2_-_49297561 0.21 ENSDART00000143471
cdc34b
cell division cycle 34 homolog (S. cerevisiae) b
chr11_-_10472565 0.20 ENSDART00000011087
ect2
epithelial cell transforming 2
chr9_+_3547661 0.20 ENSDART00000008606
mettl8
methyltransferase like 8
chr20_-_13244237 0.19 ENSDART00000124470
ints7
integrator complex subunit 7
chr11_-_18112090 0.19 ENSDART00000019248
tmem110
transmembrane protein 110
chr18_-_20469413 0.19 ENSDART00000012241
kif23
kinesin family member 23
chr13_+_49436597 0.19 ENSDART00000037559
ENSDART00000168799
ENSDART00000097845
ggps1
geranylgeranyl diphosphate synthase 1
chr1_-_17018695 0.18 ENSDART00000148322
ufsp2
ufm1-specific peptidase 2
chr21_+_3645203 0.18 ENSDART00000099535
spout1
SPOUT domain containing methyltransferase 1
chr3_-_26060702 0.18 ENSDART00000144726
ypel3
yippee-like 3
chr7_-_6328278 0.18 ENSDART00000130760
HIST2H2AB (1 of many)
histone cluster 2 H2A family member b
chr19_-_3115104 0.18 ENSDART00000093146
bop1
block of proliferation 1
chr25_+_34410718 0.17 ENSDART00000073441
sntb2
syntrophin, beta 2
chr22_-_22277386 0.17 ENSDART00000111711
chaf1a
chromatin assembly factor 1, subunit A (p150)
chr10_-_180681 0.16

chr2_+_21698145 0.16 ENSDART00000145670
ctdsplb
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr18_+_7584201 0.16 ENSDART00000163709
zgc:77650
zgc:77650
chr5_+_19703933 0.16

chr20_-_25546095 0.15 ENSDART00000145034
mrpl19
mitochondrial ribosomal protein L19
chr5_+_30386272 0.15 ENSDART00000005893
ube2g1a
ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast)
chr1_-_50438531 0.14

chr3_-_26060748 0.14 ENSDART00000144726
ypel3
yippee-like 3
chr12_+_27001284 0.14

chr16_-_43329789 0.14 ENSDART00000025877
cldn12
claudin 12
chr7_+_22710714 0.13 ENSDART00000122449
ccnb3
cyclin B3
chr8_-_9531866 0.13 ENSDART00000044000
plxna3
plexin A3
chr8_-_28359072 0.12 ENSDART00000062693
ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr11_+_30005670 0.12 ENSDART00000167618
CR790368.1
ENSDARG00000100936
chr12_+_26785950 0.12 ENSDART00000087329
znf438
zinc finger protein 438
chr18_-_20469253 0.12 ENSDART00000012241
kif23
kinesin family member 23
chr16_-_43329622 0.11 ENSDART00000025877
cldn12
claudin 12
chr3_+_12438915 0.11 ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr17_-_16414577 0.11 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr10_+_26910265 0.11 ENSDART00000166836
ehbp1l1b
EH domain binding protein 1-like 1b
chr10_-_2761480 0.11 ENSDART00000131749
ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr8_-_34509255 0.11 ENSDART00000112854
gapvd1
GTPase activating protein and VPS9 domains 1
chr10_+_26910335 0.10 ENSDART00000166836
ehbp1l1b
EH domain binding protein 1-like 1b
chr10_+_3052919 0.10 ENSDART00000028870
ube2l3a
ubiquitin-conjugating enzyme E2L 3a
chr9_+_29832294 0.10 ENSDART00000023210
trim13
tripartite motif containing 13
chr10_-_27023435 0.10 ENSDART00000050585
znhit2
zinc finger, HIT-type containing 2
chr6_+_29396163 0.10 ENSDART00000104303
actl6a
actin-like 6A
chr13_-_2211438 0.10 ENSDART00000137124
arfgef3
ARFGEF family member 3
chr13_-_17938316 0.10 ENSDART00000146772
ENSDART00000134477
zfand4
zinc finger, AN1-type domain 4
chr6_-_25065773 0.09 ENSDART00000165170
znf326
zinc finger protein 326
chr10_+_28273581 0.08 ENSDART00000131003
rnft1
ring finger protein, transmembrane 1
chr1_+_31609119 0.08 ENSDART00000135078
pudp
pseudouridine 5'-phosphatase
chr3_-_24977167 0.08 ENSDART00000055432
rbx1
ring-box 1, E3 ubiquitin protein ligase
chr23_-_16755682 0.08 ENSDART00000020810
sdcbp2
syndecan binding protein (syntenin) 2
chr18_+_23211146 0.07

chr15_+_5913761 0.06 ENSDART00000114134
wrb
tryptophan rich basic protein
chr10_+_16111920 0.06 ENSDART00000141654
megf10
multiple EGF-like-domains 10
chr15_+_8791540 0.06 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr11_+_14046768 0.05 ENSDART00000059752
med16
mediator complex subunit 16
chr7_-_67741663 0.05

chr6_+_9558204 0.04 ENSDART00000108524
als2b
amyotrophic lateral sclerosis 2b (juvenile)
chr21_-_3619164 0.04 ENSDART00000133980
scamp1
secretory carrier membrane protein 1
chr15_-_46484516 0.03 ENSDART00000154577
zgc:162872
zgc:162872
chr19_-_26109474 0.03 ENSDART00000136187
bloc1s4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr10_+_42158472 0.03 ENSDART00000160687
setd1ba
SET domain containing 1B, a
chr10_+_3053045 0.03 ENSDART00000028870
ube2l3a
ubiquitin-conjugating enzyme E2L 3a
KN149790v1_-_94139 0.02 ENSDART00000168319
zgc:171422
zgc:171422
chr21_-_26973913 0.01 ENSDART00000147090
ppp1r14ba
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.9 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.3 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652) regulation of neutrophil migration(GO:1902622)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination