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Results for hoxd3a

Z-value: 0.52

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Transcription factors associated with hoxd3a

Gene Symbol Gene ID Gene Info
hoxd3a
ENSDARG00000059280 homeobox D3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd3adr10_dc_chr9_-_1958795_19588370.888.0e-06Click!

Activity profile of hoxd3a motif

Sorted Z-values of hoxd3a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd3a

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_39141022 1.43 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr6_-_23193752 1.20 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr15_-_1858350 1.13 ENSDART00000082026
mmp28
matrix metallopeptidase 28
chr1_+_38834751 1.00 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr19_-_7069920 0.98 ENSDART00000145741
znf384l
zinc finger protein 384 like
chr20_-_9107294 0.94 ENSDART00000140792
OMA1
OMA1 zinc metallopeptidase
chr15_-_35394535 0.94 ENSDART00000144153
mff
mitochondrial fission factor
chr16_+_14817799 0.92 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr23_+_27749014 0.85 ENSDART00000128833
rps26
ribosomal protein S26
chr12_-_27032151 0.78 ENSDART00000153365
BX001014.2
ENSDARG00000096750
chr23_-_7740845 0.77 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr10_+_39148251 0.71 ENSDART00000125986
ENSDARG00000055339
ENSDARG00000055339
chr6_-_8075384 0.64 ENSDART00000129674
slc44a2
solute carrier family 44 (choline transporter), member 2
chr14_-_2682064 0.59 ENSDART00000161677
si:dkey-201i24.6
si:dkey-201i24.6
chr22_+_16282153 0.57 ENSDART00000162685
ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr8_-_19166630 0.56

chr10_-_26782374 0.54 ENSDART00000162710
fgf13b
fibroblast growth factor 13b
chr19_-_7069850 0.51 ENSDART00000145741
znf384l
zinc finger protein 384 like
chr19_+_21783111 0.50 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr5_+_62987426 0.50 ENSDART00000178937
dnm1b
dynamin 1b
chr13_-_49695322 0.49

chr1_-_50215233 0.49 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr21_+_8334453 0.48 ENSDART00000055336
dennd1a
DENN/MADD domain containing 1A
chr23_+_36016450 0.46 ENSDART00000103035
hoxc6a
homeobox C6a
chr17_-_37107310 0.46 ENSDART00000151921
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr7_+_9726412 0.46 ENSDART00000173155
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr7_+_25052687 0.45 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr23_+_17220363 0.45 ENSDART00000143420
BX927275.2
ENSDARG00000095017
chr3_+_27667194 0.43 ENSDART00000075100
carhsp1
calcium regulated heat stable protein 1
chr7_-_67906887 0.39 ENSDART00000171943
si:ch73-315f9.2
si:ch73-315f9.2
chr6_-_57542101 0.39 ENSDART00000156967
itcha
itchy E3 ubiquitin protein ligase a
chr8_+_17042976 0.38 ENSDART00000023206
plk2b
polo-like kinase 2b (Drosophila)
chr20_+_29307142 0.35 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr13_-_44492897 0.34

chr5_-_37494209 0.33 ENSDART00000084890
si:ch211-284e13.4
si:ch211-284e13.4
chr19_+_21783429 0.33 ENSDART00000024639
tshz1
teashirt zinc finger homeobox 1
chr10_+_39140943 0.32 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr5_+_65754237 0.31 ENSDART00000170757
kntc1
kinetochore associated 1
chr6_-_23193873 0.28 ENSDART00000159749
usp43a
ubiquitin specific peptidase 43a
chr8_+_25015374 0.26 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr20_-_15029379 0.26 ENSDART00000152641
dnm3a
dynamin 3a
chr20_+_29307039 0.23 ENSDART00000152949
katnbl1
katanin p80 subunit B-like 1
chr8_+_25015325 0.23 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr2_+_50873893 0.22

chr11_+_13000957 0.22 ENSDART00000161532
zfyve9b
zinc finger, FYVE domain containing 9b
chr20_-_46458839 0.20 ENSDART00000153087
bmf2
Bcl2 modifying factor 2
chr5_+_27560610 0.18 ENSDART00000051516
tacr1a
tachykinin receptor 1a
chr20_+_26012369 0.17 ENSDART00000146004
ttbk2b
tau tubulin kinase 2b
chr11_-_40464213 0.16 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr2_-_28687065 0.16 ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr15_-_5911817 0.15

chr18_-_510172 0.13 ENSDART00000164374
si:ch211-79l17.1
si:ch211-79l17.1
chr6_+_3120600 0.13 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr7_-_64172974 0.09 ENSDART00000172619
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_41910191 0.08

chr2_+_50873843 0.07

chr8_-_22252973 0.07 ENSDART00000131805
nphp4
nephronophthisis 4
chr11_-_40464253 0.06 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr10_-_41478085 0.06 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr15_-_5911548 0.05

chr20_+_29307283 0.05 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr10_-_20545884 0.05

chr21_-_32449627 0.03

chr7_-_32624437 0.02 ENSDART00000141828
ano5b
anoctamin 5b
chr14_+_22294338 0.02 ENSDART00000167829
graf4b
GDNF family receptor alpha 4b
chr11_+_35790782 0.01 ENSDART00000125221
CR933559.1
ENSDARG00000087939

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.2 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.1 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.6 GO:0015696 ammonium transport(GO:0015696)
0.0 0.6 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 1.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0042446 hormone biosynthetic process(GO:0042446)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex