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Results for ikzf1

Z-value: 0.82

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Transcription factors associated with ikzf1

Gene Symbol Gene ID Gene Info
ikzf1
ENSDARG00000013539 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ikzf1dr10_dc_chr13_-_15863571_158635740.243.7e-01Click!

Activity profile of ikzf1 motif

Sorted Z-values of ikzf1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr22_-_3264630 1.77 ENSDART00000170992
si:zfos-943e10.1
si:zfos-943e10.1
chr15_-_2677200 1.71 ENSDART00000063320
cldne
claudin e
chr20_+_4567653 1.44

chr1_-_50066633 1.36

chr11_+_6446302 1.21 ENSDART00000140707
ENSDART00000036939
gadd45ba
growth arrest and DNA-damage-inducible, beta a
chr18_+_40364675 1.16 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr1_+_29054033 1.16 ENSDART00000054066
zic2b
zic family member 2 (odd-paired homolog, Drosophila) b
chr11_+_7139675 1.16 ENSDART00000155864
CU929070.1
ENSDARG00000097452
chr11_-_27706441 1.15

chr22_-_10005524 1.08 ENSDART00000160744
BX324216.1
ENSDARG00000086839
chr12_+_31558667 1.04 ENSDART00000152971
dnmbp
dynamin binding protein
chr19_+_17832515 1.02 ENSDART00000149045
klf2b
Kruppel-like factor 2b
chr24_-_35811390 1.02 ENSDART00000167990
mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_-_70948223 0.95 ENSDART00000013404
ak1
adenylate kinase 1
chr10_+_33935945 0.95

chr15_-_2689005 0.87 ENSDART00000063325
cldnf
claudin f
chr15_-_20297270 0.84 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr5_+_30141562 0.84 ENSDART00000098246
ftr83
finTRIM family, member 83
chr24_-_8589270 0.78 ENSDART00000082346
tfap2a
transcription factor AP-2 alpha
chr15_+_42617510 0.77

chr7_-_24201833 0.76 ENSDART00000121684
nat8l
N-acetyltransferase 8-like
chr14_-_40454194 0.73 ENSDART00000166621
ef1
E74-like factor 1 (ets domain transcription factor)
chr11_-_29316162 0.72 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr20_+_4567603 0.71

chr13_-_36265504 0.70 ENSDART00000140243
actn1
actinin, alpha 1
chr23_-_30119058 0.69 ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr16_+_29558320 0.67 ENSDART00000011497
ctsk
cathepsin K
chr13_-_13163676 0.65 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
KN149990v1_+_7315 0.63

chr19_+_5375413 0.63 ENSDART00000141237
si:dkeyp-113d7.10
si:dkeyp-113d7.10
chr18_-_35415824 0.61 ENSDART00000098297
CABZ01041002.1
ENSDARG00000068104
chr24_+_16005004 0.61 ENSDART00000163086
ENSDART00000152087
si:dkey-118j18.2
si:dkey-118j18.2
chr1_-_30299017 0.60

chr24_+_38783264 0.59 ENSDART00000154214
si:ch73-70c5.1
si:ch73-70c5.1
chr24_-_2830194 0.58 ENSDART00000164913
si:ch211-152c8.5
si:ch211-152c8.5
chr16_+_46728964 0.58 ENSDART00000163571
rab25b
RAB25, member RAS oncogene family b
chr23_+_42381296 0.58 ENSDART00000158684
ENSDART00000159985
ENSDART00000172144
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr23_-_6831711 0.57 ENSDART00000125393
FP102169.1
ENSDARG00000089210
chr25_-_2485276 0.55 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr17_-_14868764 0.55 ENSDART00000115064
nid2a
nidogen 2a (osteonidogen)
chr13_-_21529695 0.54 ENSDART00000100925
mxtx1
mix-type homeobox gene 1
chr2_+_55888093 0.54 ENSDART00000146160
loxl5b
lysyl oxidase-like 5b
chr3_+_34019696 0.53 ENSDART00000006091
carm1
coactivator-associated arginine methyltransferase 1
chr11_+_18862603 0.53

chr20_-_54742983 0.52

chr15_-_33669717 0.52 ENSDART00000161151
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr2_-_58111727 0.52 ENSDART00000004431
ENSDART00000166845
ENSDART00000163999
epb41l3b
erythrocyte membrane protein band 4.1-like 3b
chr7_-_57796486 0.52 ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr12_+_29994735 0.51 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr21_+_30434147 0.51 ENSDART00000147375
snx12
sorting nexin 12
chr3_+_30790513 0.50 ENSDART00000130422
cldni
claudin i
chr11_+_5745644 0.49 ENSDART00000179139
arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr22_-_15678308 0.48 ENSDART00000130238
safb
scaffold attachment factor B
chr17_-_48623315 0.48 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr13_-_39033893 0.48 ENSDART00000045434
col9a1b
collagen, type IX, alpha 1b
chr5_+_58017820 0.47 ENSDART00000083015
ccdc84
coiled-coil domain containing 84
chr6_+_39373026 0.47 ENSDART00000157165
si:dkey-195m11.8
si:dkey-195m11.8
chr19_-_28546417 0.47 ENSDART00000130922
ENSDART00000079114
irx1b
iroquois homeobox 1b
chr4_-_7721419 0.46

chr2_-_816669 0.46 ENSDART00000122732
foxc1a
forkhead box C1a
chr22_+_15871952 0.42 ENSDART00000062587
klf2a
Kruppel-like factor 2a
chr21_+_25633278 0.42 ENSDART00000101203
sumf2
sulfatase modifying factor 2
chr12_-_28840796 0.41

chr7_-_38521262 0.41 ENSDART00000157416
si:dkey-23n7.10
si:dkey-23n7.10
chr3_+_18779544 0.41

chr5_-_25866099 0.41 ENSDART00000144035
arvcfb
armadillo repeat gene deleted in velocardiofacial syndrome b
chr18_+_17548213 0.40 ENSDART00000144960
nup93
nucleoporin 93
chr2_+_42874975 0.40 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr17_+_33462782 0.39 ENSDART00000140805
snap23.1
synaptosomal-associated protein 23.1
chr13_-_13163801 0.39 ENSDART00000156968
fgfr3
fibroblast growth factor receptor 3
chr16_+_39396358 0.39

chr11_-_4216204 0.38 ENSDART00000121716
ENSDARG00000086300
ENSDARG00000086300
chr10_+_34377959 0.37

chr8_-_15144533 0.37 ENSDART00000138855
bcar3
breast cancer anti-estrogen resistance 3
chr9_-_30744878 0.37 ENSDART00000079222
chaf1b
chromatin assembly factor 1, subunit B
chr18_-_14891913 0.37 ENSDART00000018502
mapk12a
mitogen-activated protein kinase 12a
chr13_+_49527181 0.37 ENSDART00000176643
CABZ01084653.1
ENSDARG00000106801
chr10_+_32007448 0.36 ENSDART00000019416
lhfp
lipoma HMGIC fusion partner
chr19_-_23037220 0.36 ENSDART00000090669
pleca
plectin a
chr9_-_21677993 0.35 ENSDART00000121939
ENSDART00000080404
mphosph8
M-phase phosphoprotein 8
chr16_+_53238110 0.35 ENSDART00000102170
CABZ01053976.1
ENSDARG00000069929
chr16_+_26892979 0.35 ENSDART00000048036
gem
GTP binding protein overexpressed in skeletal muscle
chr23_-_30861356 0.35 ENSDART00000114628
myt1a
myelin transcription factor 1a
chr16_+_5256773 0.35 ENSDART00000012053
elovl4a
ELOVL fatty acid elongase 4a
chr3_+_31793328 0.34 ENSDART00000127330
ENSDART00000126773
ENSDART00000055279
snrnp70
small nuclear ribonucleoprotein 70 (U1)
chr5_-_67580755 0.34 ENSDART00000169350
ENSDARG00000098655
ENSDARG00000098655
chr3_+_3955069 0.34 ENSDART00000092393
plbd1
phospholipase B domain containing 1
chr21_+_18295124 0.34 ENSDART00000167511
ENSDARG00000104101
ENSDARG00000104101
chr1_+_8605984 0.34 ENSDART00000055009
uncx4.1
Unc4.1 homeobox (C. elegans)
chr5_+_31745031 0.34 ENSDART00000147132
c9
complement component 9
chr12_+_24994481 0.33 ENSDART00000170466
gch2
GTP cyclohydrolase 2
chr16_+_7874573 0.33

chr2_+_2583068 0.33

chr3_+_52901602 0.33 ENSDART00000114343
brd4
bromodomain containing 4
chr3_-_19913881 0.33 ENSDART00000126915
ubtf
upstream binding transcription factor, RNA polymerase I
chr7_-_24119645 0.32 ENSDART00000141769
ptgr1
prostaglandin reductase 1
chr12_-_37921731 0.32

chr25_+_18467217 0.32 ENSDART00000170841
cav1
caveolin 1
chr14_+_21999898 0.31

chr11_+_12802775 0.31 ENSDART00000037474
zgpat
zinc finger, CCCH-type with G patch domain
chr24_-_8589388 0.31 ENSDART00000082346
tfap2a
transcription factor AP-2 alpha
chr1_-_53746151 0.31 ENSDART00000179565
CABZ01043826.1
ENSDARG00000108130
chr19_+_43487281 0.30

chr2_-_43347158 0.30 ENSDART00000141087
crema
cAMP responsive element modulator a
chr2_-_10555152 0.30 ENSDART00000150166
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr2_-_32521879 0.29 ENSDART00000056639
faim2a
Fas apoptotic inhibitory molecule 2a
chr21_-_2143830 0.29

chr12_-_5693715 0.29 ENSDART00000105887
dlx4b
distal-less homeobox 4b
chr2_-_42643045 0.29 ENSDART00000139929
esyt2a
extended synaptotagmin-like protein 2a
chr2_+_42342148 0.29 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr18_+_45680282 0.29 ENSDART00000109948
qser1
glutamine and serine rich 1
chr5_-_1325831 0.29

chr20_-_34389652 0.28 ENSDART00000144705
ENSDART00000020389
hmcn1
hemicentin 1
chr7_-_17460601 0.28 ENSDART00000149047
men1
multiple endocrine neoplasia I
chr16_+_5470544 0.28

chr16_+_24047649 0.28

chr16_+_21109486 0.28 ENSDART00000079383
hoxa9b
homeobox A9b
chr14_-_45887823 0.27 ENSDART00000178932
ENSDART00000160657
cltb
clathrin, light chain B
chr8_-_23744125 0.27 ENSDART00000141871
INAVA
innate immunity activator
chr20_-_7303804 0.26 ENSDART00000100060
dsc2l
desmocollin 2 like
chr13_+_17333810 0.26 ENSDART00000134181
CT025897.1
ENSDARG00000093577
chr9_-_21257082 0.26 ENSDART00000124533
tbx15
T-box 15
chr13_-_36265476 0.26 ENSDART00000133740
ENSDART00000100217
actn1
actinin, alpha 1
chr23_-_26150495 0.26 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr6_+_6333766 0.26 ENSDART00000140827
bcl11ab
B-cell CLL/lymphoma 11Ab
chr6_-_16328987 0.25 ENSDART00000083305
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr6_+_30441419 0.25

chr8_-_13026629 0.25 ENSDART00000129168
si:dkey-208b23.5
si:dkey-208b23.5
chr12_-_26339002 0.25 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr5_+_65754237 0.25 ENSDART00000170757
kntc1
kinetochore associated 1
chr2_-_44402486 0.25 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr19_+_12663944 0.25 ENSDART00000151508
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr8_+_20456215 0.25 ENSDART00000036630
zgc:101100
zgc:101100
chr25_+_11317025 0.24

chr18_+_45680493 0.24 ENSDART00000109948
qser1
glutamine and serine rich 1
chr24_-_34794463 0.24 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr21_+_45629613 0.24

chr6_-_8156520 0.24 ENSDART00000081561
ilf3a
interleukin enhancer binding factor 3a
chr20_-_54200627 0.24

chr5_+_39619826 0.23 ENSDART00000114078
si:dkey-193c22.2
si:dkey-193c22.2
chr4_-_12915292 0.23 ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr13_-_37001997 0.23 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr16_-_54634679 0.23 ENSDART00000075275
ENSDART00000115024
pklr
pyruvate kinase, liver and RBC
chr25_+_5922190 0.23 ENSDART00000128816
sv2
synaptic vesicle glycoprotein 2
chr18_-_44365869 0.23 ENSDART00000166935
prdm10
PR domain containing 10
chr20_+_27613739 0.22

chr5_+_36690093 0.22 ENSDART00000114671
ENSDART00000113642
zgc:163098
zgc:163098
chr16_-_31835463 0.22 ENSDART00000148389
chd4b
chromodomain helicase DNA binding protein 4b
chr2_-_1752776 0.22 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr7_-_58751849 0.22 ENSDART00000165390
chmp5b
charged multivesicular body protein 5b
chr24_+_40625215 0.22

chr18_-_46831863 0.22

chr2_-_1753058 0.22 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr20_+_35156202 0.22 ENSDART00000165899
ENSDART00000122696
hnrnpub
heterogeneous nuclear ribonucleoprotein Ub
chr16_+_41922320 0.22

chr15_-_25582891 0.21

chr21_+_38025480 0.21 ENSDART00000142106
klf8
Kruppel-like factor 8
chr10_+_38582701 0.21 ENSDART00000144329
acer3
alkaline ceramidase 3
chr23_+_20522512 0.21 ENSDART00000137294
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr9_-_52788707 0.20

chr9_-_9693002 0.20 ENSDART00000018228
gsk3b
glycogen synthase kinase 3 beta
chr14_-_23501428 0.20

chr23_+_6861489 0.20 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr19_-_7372767 0.20 ENSDART00000137654
sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr21_+_7844259 0.20 ENSDART00000027268
otpa
orthopedia homeobox a
chr13_-_7897936 0.19 ENSDART00000139728
si:ch211-250c4.4
si:ch211-250c4.4
chr19_-_46396376 0.19

chr14_+_16508093 0.19 ENSDART00000161201
limch1b
LIM and calponin homology domains 1b
chr23_+_1721759 0.19 ENSDART00000149545
tgm1
transglutaminase 1, K polypeptide
chr4_+_5370319 0.19 ENSDART00000163797
ENSDARG00000014395
ENSDARG00000014395
chr15_-_23441268 0.19 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr1_-_52869817 0.19 ENSDART00000162025
ENSDART00000100788
commd1
copper metabolism (Murr1) domain containing 1
chr14_-_5371581 0.18 ENSDART00000012116
tlx2
T-cell leukemia, homeobox 2
chr10_+_4987494 0.18 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr1_-_23603046 0.18

chr18_+_20504980 0.18 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr25_-_14948922 0.18 ENSDART00000161165
pax6a
paired box 6a
chr3_-_60522527 0.18 ENSDART00000166334
srsf2b
serine/arginine-rich splicing factor 2b
chr20_+_51388214 0.18 ENSDART00000153452
hsp90ab1
heat shock protein 90, alpha (cytosolic), class B member 1
chr3_+_17465729 0.18 ENSDART00000034536
rab5c
RAB5C, member RAS oncogene family
chr3_+_29583029 0.18

chr13_-_508202 0.18 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr20_+_35156072 0.18 ENSDART00000165899
ENSDART00000122696
hnrnpub
heterogeneous nuclear ribonucleoprotein Ub
chr4_+_292818 0.18 ENSDART00000103659
msgn1
mesogenin 1
chr7_-_18751216 0.17 ENSDART00000157618
HACD4
3-hydroxyacyl-CoA dehydratase 4
chr6_-_2028814 0.17 ENSDART00000171265
tgm5l
transglutaminase 5, like
chr11_-_18004011 0.17 ENSDART00000125800
CABZ01112210.1
ENSDARG00000088766
chr19_-_7151715 0.17 ENSDART00000168755
tapbp.2
TAP binding protein (tapasin), tandem duplicate 2
chr1_-_30298698 0.17

chr17_-_14663139 0.17 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr6_+_14854074 0.17 ENSDART00000087782
mrps9
mitochondrial ribosomal protein S9
chr25_+_31746643 0.17 ENSDART00000162636
tjp1b
tight junction protein 1b
chr20_+_8041008 0.17 ENSDART00000085668
prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr6_-_39767452 0.17 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr7_-_28300008 0.17

chr6_-_30671802 0.17 ENSDART00000065215
lurap1
leucine rich adaptor protein 1
chr10_+_6925975 0.16

chr21_-_40389601 0.16 ENSDART00000003221
nsrp1
nuclear speckle splicing regulatory protein 1
chr2_-_1753013 0.16 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr7_-_33791033 0.16 ENSDART00000052404
map2k5
mitogen-activated protein kinase kinase 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.4 1.2 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.2 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 0.9 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.2 0.5 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) regulation of somitogenesis(GO:0014807) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 1.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 3.1 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0046931 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.1 0.5 GO:0018057 peptidyl-lysine oxidation(GO:0018057) protein oxidation(GO:0018158)
0.1 0.3 GO:0010084 specification of organ axis polarity(GO:0010084) specification of axis polarity(GO:0065001)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.3 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 0.7 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.1 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036) iridophore differentiation(GO:0050935)
0.1 0.2 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.2 GO:0070254 mucus secretion(GO:0070254)
0.1 0.2 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 0.3 GO:1990280 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) regulation of mitotic attachment of spindle microtubules to kinetochore(GO:1902423) positive regulation of attachment of mitotic spindle microtubules to kinetochore(GO:1902425) RNA localization to chromatin(GO:1990280)
0.1 1.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0060394 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0 0.2 GO:0036363 transforming growth factor beta activation(GO:0036363) transforming growth factor beta production(GO:0071604) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.2 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.3 GO:0045117 azole transport(GO:0045117)
0.0 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.1 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.0 0.7 GO:0001757 somite specification(GO:0001757)
0.0 0.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.2 GO:0061615 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0090109 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.4 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.6 GO:0009612 response to mechanical stimulus(GO:0009612)
0.0 0.2 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) positive regulation of leukocyte chemotaxis(GO:0002690) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.5 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0021767 mammillary body development(GO:0021767)
0.0 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0032467 mitotic spindle elongation(GO:0000022) positive regulation of cytokinesis(GO:0032467) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0098594 mucin granule(GO:0098594)
0.1 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.3 GO:0000803 sex chromosome(GO:0000803) inactive sex chromosome(GO:0098577)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 3.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 1.3 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0017130 TFIIH-class transcription factor binding(GO:0001097) poly(C) RNA binding(GO:0017130)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.4 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.2 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:1901474 azole transporter activity(GO:0045118) vitamin transmembrane transporter activity(GO:0090482) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination