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Results for ikzf2

Z-value: 1.62

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Transcription factors associated with ikzf2

Gene Symbol Gene ID Gene Info
ikzf2
ENSDARG00000069111 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2dr10_dc_chr9_-_40212643_402126510.932.1e-07Click!

Activity profile of ikzf2 motif

Sorted Z-values of ikzf2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_30790513 7.00 ENSDART00000130422
cldni
claudin i
chr11_+_21749658 5.68 ENSDART00000161485
foxp4
forkhead box P4
chr1_+_1541977 5.60 ENSDART00000048828
atp1a1a.4
ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 4
chr3_-_48865474 5.27 ENSDART00000133036
elavl3
ELAV like neuron-specific RNA binding protein 3
chr16_+_23482744 5.08 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr7_-_35161302 4.60 ENSDART00000026712
mmp2
matrix metallopeptidase 2
chr23_-_39956151 3.50 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr3_+_54876680 3.17 ENSDART00000111585
hbbe1.3
hemoglobin, beta embryonic 1.3
chr5_+_8935212 3.11

chr24_-_23175007 3.09 ENSDART00000112256
zfhx4
zinc finger homeobox 4
chr13_+_24531753 2.84 ENSDART00000014176
msx3
muscle segment homeobox 3
chr7_-_2239498 2.80 ENSDART00000173892
si:cabz01007794.1
si:cabz01007794.1
chr18_+_26437604 2.79 ENSDART00000060245
ctsh
cathepsin H
chr3_-_19942214 2.78 ENSDART00000029386
slc4a1a
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr14_+_23980348 2.69 ENSDART00000160984
BX005228.1
ENSDARG00000105465
chr14_-_42633578 2.65 ENSDART00000162714
ENSDART00000161521
pcdh10b
protocadherin 10b
chr7_+_25649559 2.55 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr12_-_9479063 2.52 ENSDART00000169727
si:ch211-207i20.3
si:ch211-207i20.3
chr16_+_26900732 2.51 ENSDART00000042895
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr16_+_19926776 2.47 ENSDART00000149901
ENSDART00000052927
twist1b
twist family bHLH transcription factor 1b
chr23_-_21520413 2.47 ENSDART00000044080
ENSDART00000112929
her12
hairy-related 12
chr2_-_43998886 2.45 ENSDART00000146493
zeb1a
zinc finger E-box binding homeobox 1a
chr20_-_21031504 2.44 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr18_+_48433986 2.39 ENSDART00000076861
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr6_+_29800606 2.38 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr18_+_19659195 2.37 ENSDART00000100569
smad6b
SMAD family member 6b
chr1_+_8605984 2.37 ENSDART00000055009
uncx4.1
Unc4.1 homeobox (C. elegans)
chr4_-_24298444 2.37 ENSDART00000077926
ENSDART00000128368
celf2
cugbp, Elav-like family member 2
chr17_+_33766838 2.31 ENSDART00000132294
fut8a
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr3_+_13114740 2.29 ENSDART00000162724
ENSDARG00000074231
ENSDARG00000074231
chr2_+_3701942 2.26 ENSDART00000132572
gpt2l
glutamic pyruvate transaminase (alanine aminotransferase) 2, like
chr16_+_5470544 2.26

chr9_+_53736715 2.24 ENSDART00000003310
sox21b
SRY (sex determining region Y)-box 21b
chr16_+_17705704 2.21

chr15_+_19902697 2.20 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr25_-_255242 2.20

chr14_+_21531709 2.16 ENSDART00000144367
ctbp1
C-terminal binding protein 1
chr22_-_19986461 2.16 ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr24_-_23174888 2.14 ENSDART00000112256
zfhx4
zinc finger homeobox 4
chr3_-_24925189 2.14 ENSDART00000156459
ep300b
E1A binding protein p300 b
chr3_+_37565550 2.14 ENSDART00000151236
map3k14a
mitogen-activated protein kinase kinase kinase 14a
chr1_-_55554518 2.12 ENSDART00000019573
zgc:65894
zgc:65894
chr2_-_30071872 2.11 ENSDART00000056747
shhb
sonic hedgehog b
chr20_-_29148810 2.11 ENSDART00000140350
thbs1b
thrombospondin 1b
chr12_-_48493654 2.10 ENSDART00000162603
ndufb8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr2_+_29992879 2.09 ENSDART00000056748
en2b
engrailed homeobox 2b
chr7_-_33080261 2.09 ENSDART00000114041
anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr23_+_25782195 2.08 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr9_-_24183317 2.07 ENSDART00000140346
col6a3
collagen, type VI, alpha 3
chr1_+_45063098 2.07 ENSDART00000084512
pkn1a
protein kinase N1a
chr5_-_33265038 2.06 ENSDART00000132634
BX005445.1
ENSDARG00000095064
chr21_-_7277655 2.05 ENSDART00000056561
s100z
S100 calcium binding protein Z
chr23_-_20837809 2.04 ENSDART00000089750
znf362b
zinc finger protein 362b
chr15_+_30276801 2.03 ENSDART00000047248
ENSDART00000123937
nlk2
nemo-like kinase, type 2
chr8_+_10267246 1.94 ENSDART00000159312
ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr23_+_23730717 1.94

chr7_+_36280563 1.92 ENSDART00000027807
chd9
chromodomain helicase DNA binding protein 9
chr16_+_29558320 1.92 ENSDART00000011497
ctsk
cathepsin K
chr21_+_5693372 1.89 ENSDART00000020603
ccng2
cyclin G2
chr1_-_5796394 1.86 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr7_-_72278552 1.85 ENSDART00000168532
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chr23_+_35988395 1.85 ENSDART00000154825
hoxc3a
homeo box C3a
chr1_+_6995893 1.84 ENSDART00000163488
en1b
engrailed homeobox 1b
chr5_-_63422783 1.83 ENSDART00000083684
pappab
pregnancy-associated plasma protein A, pappalysin 1b
chr7_+_39116005 1.80 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr22_+_13862110 1.80 ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr7_+_58443471 1.78 ENSDART00000148851
rps20
ribosomal protein S20
chr6_-_12487617 1.77 ENSDART00000090174
dock9b
dedicator of cytokinesis 9b
chr14_+_20632593 1.77 ENSDART00000166366
ENSDART00000106198
zgc:66433
zgc:66433
chr2_+_21342233 1.76 ENSDART00000062563
rreb1b
ras responsive element binding protein 1b
chr13_-_47767713 1.75 ENSDART00000045475
itga9
integrin, alpha 9
chr6_+_35378839 1.74 ENSDART00000102483
ENSDART00000133783
rgs4
regulator of G protein signaling 4
chr5_-_25866099 1.74 ENSDART00000144035
arvcfb
armadillo repeat gene deleted in velocardiofacial syndrome b
chr19_+_1814994 1.74

chr11_-_32461160 1.74 ENSDART00000155592
pcdh17
protocadherin 17
chr16_+_33702010 1.71 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr23_-_7740845 1.71 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr7_-_46509291 1.69 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr3_+_29583029 1.68

chr23_+_36002332 1.65 ENSDART00000103139
hoxc8a
homeobox C8a
chr11_-_25962291 1.64

chr10_+_9325719 1.63 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr17_+_52736192 1.63 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr10_+_10428297 1.63 ENSDART00000179214
sardh
sarcosine dehydrogenase
chr3_+_12432686 1.62

chr5_-_68145952 1.61 ENSDART00000141917
ank1a
ankyrin 1, erythrocytic a
chr6_-_36574848 1.60 ENSDART00000135413
her6
hairy-related 6
chr13_-_47767748 1.60 ENSDART00000045475
itga9
integrin, alpha 9
chr24_-_9151388 1.59 ENSDART00000149875
tgif1
TGFB-induced factor homeobox 1
chr19_-_20614846 1.59 ENSDART00000155527
si:ch211-155k24.9
si:ch211-155k24.9
chr8_+_46651079 1.57 ENSDART00000113803
her3
hairy-related 3
chr13_+_4536343 1.55

chr1_-_40208544 1.55 ENSDART00000027463
hmx4
H6 family homeobox 4
chr21_-_24552672 1.54

chr19_-_10324632 1.54 ENSDART00000148073
shisa7b
shisa family member 7
chr6_+_58921655 1.52 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr21_-_20674965 1.51 ENSDART00000065649
ENSDARG00000044676
ENSDARG00000044676
chr25_+_30472954 1.51

chr2_-_21960233 1.51 ENSDART00000027587
ralab
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr5_+_34397578 1.50 ENSDART00000043341
foxd1
forkhead box D1
chr13_-_23536022 1.49

chr2_-_30071815 1.48 ENSDART00000056747
shhb
sonic hedgehog b
chr3_-_48865399 1.47 ENSDART00000028610
elavl3
ELAV like neuron-specific RNA binding protein 3
chr17_+_22082952 1.47 ENSDART00000047772
mal
mal, T-cell differentiation protein
chr18_+_7632469 1.46 ENSDART00000136313
si:dkeyp-1h4.6
si:dkeyp-1h4.6
chr3_+_34064081 1.45

chr7_+_20272091 1.45 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr9_+_56182756 1.45 ENSDART00000144757
mxra5b
matrix-remodelling associated 5b
chr25_-_13057808 1.45 ENSDART00000172571
smpd3
sphingomyelin phosphodiesterase 3, neutral
chr8_-_52426509 1.45 ENSDART00000015081
ENSDARG00000011208
ENSDARG00000011208
chr11_-_25803101 1.44 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr12_+_28252623 1.44 ENSDART00000066294
cdk5r1b
cyclin-dependent kinase 5, regulatory subunit 1b (p35)
chr4_+_18854068 1.43 ENSDART00000066977
bik
BCL2-interacting killer (apoptosis-inducing)
chr9_-_23346038 1.43 ENSDART00000135461
lypd6b
LY6/PLAUR domain containing 6B
chr1_-_51862897 1.43 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr1_-_40208469 1.42 ENSDART00000027463
hmx4
H6 family homeobox 4
chr11_-_23151247 1.42

chr23_+_25392850 1.42

chr13_+_13562712 1.42 ENSDART00000110509
ENSDART00000169265
si:ch211-194c3.5
si:ch211-194c3.5
chr4_+_5240888 1.41 ENSDART00000150391
si:ch211-214j24.14
si:ch211-214j24.14
chr5_-_21523520 1.40 ENSDART00000023306
asb12a
ankyrin repeat and SOCS box-containing 12a
chr3_-_12432661 1.40

chr7_-_54407681 1.39 ENSDART00000162795
ccnd1
cyclin D1
chr23_+_6298911 1.38 ENSDART00000139795
syt2a
synaptotagmin IIa
chr22_-_24341408 1.38

chr9_+_46038777 1.37 ENSDART00000114814
twist2
twist2
chr16_+_19731017 1.37 ENSDART00000139357
sp8b
sp8 transcription factor b
chr11_+_21749918 1.35 ENSDART00000161485
foxp4
forkhead box P4
chr24_+_9231693 1.34 ENSDART00000082422
si:ch211-285f17.1
si:ch211-285f17.1
chr6_+_39362786 1.34 ENSDART00000151322
ENSDARG00000028618
ENSDARG00000028618
chr5_+_19924978 1.34 ENSDART00000141118
tmem119a
transmembrane protein 119a
chr9_-_33518818 1.34 ENSDART00000140039
rpl8
ribosomal protein L8
chr4_-_23362106 1.33 ENSDART00000133644
ENSDART00000009768
magi2a
membrane associated guanylate kinase, WW and PDZ domain containing 2a
chr4_+_4223606 1.33

chr2_-_54965656 1.33

chr19_+_15538967 1.32 ENSDART00000171403
lin28a
lin-28 homolog A (C. elegans)
chr24_-_11681151 1.31 ENSDART00000058992
gli3
GLI family zinc finger 3
chr22_+_34738389 1.30 ENSDART00000154372
hoga1
4-hydroxy-2-oxoglutarate aldolase 1
chr24_-_11681037 1.30 ENSDART00000058992
gli3
GLI family zinc finger 3
chr4_-_6558919 1.29 ENSDART00000142087
foxp2
forkhead box P2
KN150442v1_-_35734 1.29

chr8_+_7655655 1.29 ENSDART00000170184
fgd1
FYVE, RhoGEF and PH domain containing 1
chr12_-_7902815 1.28 ENSDART00000088100
ank3b
ankyrin 3b
chr25_-_21618526 1.28 ENSDART00000152011
DOCK4 (1 of many)
dedicator of cytokinesis 4
chr24_+_14093524 1.27

chr23_-_18972097 1.25 ENSDART00000133826
CR847953.1
ENSDARG00000057403
chr22_-_16009772 1.24

chr14_+_33073643 1.23 ENSDART00000052780
ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr16_-_10089440 1.23 ENSDART00000066372
id4
inhibitor of DNA binding 4
chr4_+_52697064 1.23

chr13_-_16126849 1.22 ENSDART00000079745
zgc:110045
zgc:110045
chr23_-_27721250 1.22 ENSDART00000059974
wnt10b
wingless-type MMTV integration site family, member 10b
chr16_+_5466342 1.22 ENSDART00000160008
plecb
plectin b
chr21_+_25597814 1.22 ENSDART00000110705
tmem151a
transmembrane protein 151A
chr7_+_73598802 1.21 ENSDART00000109720
zgc:163061
zgc:163061
chr3_+_23587156 1.20

chr10_-_36864268 1.19 ENSDART00000165853
dhrs13a.1
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr7_-_40713381 1.19 ENSDART00000031700
en2a
engrailed homeobox 2a
chr14_-_14260824 1.19 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr6_+_4000287 1.19 ENSDART00000111817
trim25l
tripartite motif containing 25, like
chr21_+_5293086 1.18

chr19_-_30834919 1.17 ENSDART00000043554
ppp1r10
protein phosphatase 1, regulatory subunit 10
chr3_+_23561502 1.17 ENSDART00000078453
hoxb7a
homeobox B7a
chr1_-_22144014 1.17 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr12_-_3742062 1.16 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr9_+_5884066 1.15 ENSDART00000129117
pdzk1
PDZ domain containing 1
chr20_+_26803282 1.15 ENSDART00000077753
foxc1b
forkhead box C1b
chr4_-_16365281 1.15 ENSDART00000139919
lum
lumican
chr13_+_22134507 1.14 ENSDART00000060576
myoz1a
myozenin 1a
chr23_-_45266310 1.14

chr9_-_8475669 1.13 ENSDART00000110158
irs2b
insulin receptor substrate 2b
chr7_+_19300351 1.12 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr11_+_33972923 1.12 ENSDART00000172594
fam43a
family with sequence similarity 43, member A
chr9_+_38814714 1.11 ENSDART00000114728
znf148
zinc finger protein 148
chr12_-_34786844 1.10 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr23_-_26562635 1.10 ENSDART00000168052
magi3a
membrane associated guanylate kinase, WW and PDZ domain containing 3a
chr3_-_19942332 1.10 ENSDART00000124326
slc4a1a
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr1_-_23771836 1.09 ENSDART00000126950
sh3d19
SH3 domain containing 19
chr19_+_30210743 1.08 ENSDART00000167803
marcksl1b
MARCKS-like 1b
chr13_-_31516399 1.08 ENSDART00000172375
ENSDART00000125987
ENSDART00000143903
ENSDART00000158719
six4a
SIX homeobox 4a
chr25_-_13456748 1.08 ENSDART00000139290
ano10b
anoctamin 10b
chr22_-_19986607 1.07 ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr19_-_46058954 1.07 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr22_-_18724510 1.07 ENSDART00000167466
midn
midnolin
chr23_+_36007936 1.06 ENSDART00000128533
hoxc3a
homeo box C3a
chr5_-_43686611 1.06 ENSDART00000146080
si:ch73-337l15.2
si:ch73-337l15.2
chr4_+_11054808 1.06 ENSDART00000140362
ccdc59
coiled-coil domain containing 59
chr12_+_1021520 1.06

chr21_-_20728623 1.05 ENSDART00000135940
ENSDART00000002231
ghrb
growth hormone receptor b
chr23_+_35988426 1.05 ENSDART00000154825
hoxc3a
homeo box C3a
chr5_-_54026450 1.04 ENSDART00000159009
spag8
sperm associated antigen 8
chr14_-_15651090 1.04 ENSDART00000169197
flt4
fms-related tyrosine kinase 4
chr16_+_33701759 1.04 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr10_+_39140943 1.03 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr6_-_54103765 1.03 ENSDART00000083880
hyal2a
hyaluronoglucosaminidase 2a
chr16_-_34304851 1.03 ENSDART00000145485
phactr4b
phosphatase and actin regulator 4b
chr16_+_17706003 1.03

chr7_-_54407461 1.03 ENSDART00000162795
ccnd1
cyclin D1
chr24_+_16005004 1.03 ENSDART00000163086
ENSDART00000152087
si:dkey-118j18.2
si:dkey-118j18.2
chr2_-_30071993 1.02 ENSDART00000056747
shhb
sonic hedgehog b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0043393 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.8 2.4 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.6 5.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.5 1.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.5 4.6 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.4 1.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.4 4.6 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.4 1.6 GO:1901052 sarcosine metabolic process(GO:1901052)
0.4 1.2 GO:0035790 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.4 1.8 GO:0031571 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.4 0.7 GO:0098900 regulation of action potential(GO:0098900)
0.3 5.9 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 1.0 GO:0060855 selective angioblast sprouting(GO:0035474) venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.3 2.3 GO:0036065 fucosylation(GO:0036065)
0.3 4.2 GO:0021794 thalamus development(GO:0021794)
0.3 4.0 GO:0015701 bicarbonate transport(GO:0015701)
0.3 0.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.3 3.2 GO:0015671 oxygen transport(GO:0015671)
0.3 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 7.0 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.3 1.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.0 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.5 GO:0071632 optomotor response(GO:0071632)
0.2 0.7 GO:0032475 otolith formation(GO:0032475)
0.2 1.4 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 3.0 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 0.9 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 1.3 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.2 0.6 GO:0051701 interaction with host(GO:0051701)
0.2 5.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 1.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 1.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.2 1.5 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.2 0.9 GO:0035777 pronephric distal tubule development(GO:0035777)
0.2 2.5 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.2 1.0 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 1.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.2 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.1 0.6 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0060997 dendritic spine development(GO:0060996) dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.1 0.7 GO:0010887 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.5 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.1 0.4 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.1 1.0 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 1.3 GO:0045471 response to ethanol(GO:0045471)
0.1 0.4 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.8 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 0.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.9 GO:0030168 platelet activation(GO:0030168)
0.1 0.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.9 GO:0016486 peptide hormone processing(GO:0016486)
0.1 4.1 GO:0030901 midbrain development(GO:0030901)
0.1 0.6 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.9 GO:0009612 response to mechanical stimulus(GO:0009612)
0.1 2.3 GO:0043113 receptor clustering(GO:0043113)
0.1 3.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 2.0 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 3.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.1 GO:0033339 pectoral fin development(GO:0033339)
0.1 0.8 GO:0042743 hydrogen peroxide metabolic process(GO:0042743)
0.1 0.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 2.1 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1 0.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 2.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 2.1 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 0.9 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.2 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 0.2 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.6 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.9 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.5 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 1.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 2.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 9.9 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.1 GO:0072045 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) convergent extension involved in nephron morphogenesis(GO:0072045)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.9 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 7.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.8 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.9 GO:0043049 otic placode formation(GO:0043049)
0.0 1.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.2 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 8.7 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 1.7 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.2 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.7 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:1903707 negative regulation of hemopoiesis(GO:1903707)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0006284 base-excision repair(GO:0006284)
0.0 1.9 GO:0048593 camera-type eye morphogenesis(GO:0048593)
0.0 0.5 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.3 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.7 GO:0006909 phagocytosis(GO:0006909)
0.0 1.7 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0033077 B cell differentiation(GO:0030183) T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.2 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 1.0 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.3 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0018196 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.5 3.2 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.2 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.2 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 4.0 GO:0008305 integrin complex(GO:0008305)
0.1 9.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.9 GO:0002102 podosome(GO:0002102)
0.1 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 2.5 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 3.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 8.5 GO:0030017 sarcomere(GO:0030017)
0.1 3.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.3 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 16.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.8 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 4.4 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0045180 basal part of cell(GO:0045178) basal cortex(GO:0045180)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.5 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.0 0.9 GO:0030658 transport vesicle membrane(GO:0030658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.6 2.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.6 5.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.5 1.6 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.5 1.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.5 7.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 4.6 GO:0005113 patched binding(GO:0005113)
0.5 3.2 GO:0031720 haptoglobin binding(GO:0031720)
0.5 1.8 GO:0004046 aminoacylase activity(GO:0004046)
0.4 1.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.3 1.0 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.3 4.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.3 0.9 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 1.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.3 1.1 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 3.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.7 GO:0043495 protein anchor(GO:0043495)
0.2 2.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.2 1.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.6 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 1.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 2.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 0.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 0.5 GO:0004953 icosanoid receptor activity(GO:0004953)
0.2 1.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 1.0 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 0.5 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 1.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 2.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0008199 ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 7.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 2.0 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.7 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.6 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.9 GO:0005109 frizzled binding(GO:0005109)
0.1 0.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 5.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.5 GO:0019003 GDP binding(GO:0019003)
0.0 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.0 59.2 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 3.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.0 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0019870 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 8.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.3 3.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 4.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 1.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 1.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.2 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.5 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 1.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 3.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 4.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC