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Results for insm1a+insm1b

Z-value: 0.93

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Transcription factors associated with insm1a+insm1b

Gene Symbol Gene ID Gene Info
insm1b
ENSDARG00000053301 insulinoma-associated 1b
insm1a
ENSDARG00000091756 insulinoma-associated 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
insm1adr10_dc_chr20_-_48677794_486778110.862.3e-05Click!
insm1bdr10_dc_chr17_+_41475052_414750730.836.4e-05Click!

Activity profile of insm1a+insm1b motif

Sorted Z-values of insm1a+insm1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of insm1a+insm1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_15774816 3.57 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr13_+_371940 3.09 ENSDART00000013007
degs1
delta(4)-desaturase, sphingolipid 1
chr3_+_54876680 2.93 ENSDART00000111585
hbbe1.3
hemoglobin, beta embryonic 1.3
chr19_+_43039606 2.41 ENSDART00000010104
crtap
cartilage associated protein
chr22_+_26543146 2.39

chr12_+_27370834 2.23 ENSDART00000105661
meox1
mesenchyme homeobox 1
chr2_+_24852094 2.01 ENSDART00000052063
rps28
ribosomal protein S28
chr4_-_17420378 1.95 ENSDART00000011943
pah
phenylalanine hydroxylase
chr5_+_42406222 1.93 ENSDART00000009182
aqp3a
aquaporin 3a
chr12_-_7669319 1.92

chr6_-_10593395 1.91 ENSDART00000020261
chrna1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr18_+_7607055 1.85 ENSDART00000140784
CR318588.4
ENSDARG00000095556
chr17_+_27383737 1.85 ENSDART00000156756
FP017274.1
ENSDARG00000097369
chr5_+_8415025 1.75 ENSDART00000046440
agpat9l
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr21_+_5693372 1.67 ENSDART00000020603
ccng2
cyclin G2
chr13_+_22173410 1.63 ENSDART00000173405
usp54a
ubiquitin specific peptidase 54a
chr3_-_45420882 1.59 ENSDART00000161507
zgc:153426
zgc:153426
chr7_-_54407681 1.52 ENSDART00000162795
ccnd1
cyclin D1
chr23_+_44951868 1.51

chr6_-_39311711 1.48

chr2_+_33057931 1.47

chr1_-_18110990 1.45 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr24_-_2918801 1.43 ENSDART00000164776
fam69c
family with sequence similarity 69, member C
chr3_+_14238188 1.38 ENSDART00000165452
ENSDART00000171726
tmem56b
transmembrane protein 56b
chr12_-_1544844 1.37

chr6_+_13833991 1.36

chr6_-_8501230 1.28 ENSDART00000143956
cavin2b
caveolae associated protein 2b
chr20_-_9212177 1.20 ENSDART00000064140
ylpm1
YLP motif containing 1
chr14_+_14262816 1.19 ENSDART00000164749
pcdh20
protocadherin 20
chr10_-_15090647 1.18 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr7_+_22314304 1.18 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr5_+_61753772 1.18

chr7_-_6219627 1.14 ENSDART00000172898
HIST2H2AB (1 of many)
zgc:165551
chr25_-_23949331 1.12 ENSDART00000047569
igf2b
insulin-like growth factor 2b
chr19_+_42491631 1.11 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr11_-_25803101 1.09 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr8_-_14446883 1.06 ENSDART00000057644
lhx4
LIM homeobox 4
chr8_-_37358627 1.04 ENSDART00000009569
slc12a5b
solute carrier family 12 (potassium/chloride transporter), member 5b
chr12_-_4648262 1.02 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr11_+_25382443 1.00 ENSDART00000033702
comtb
catechol-O-methyltransferase b
chr3_+_17210396 0.99 ENSDART00000090676
si:ch211-210g13.5
si:ch211-210g13.5
chr7_-_54407461 0.99 ENSDART00000162795
ccnd1
cyclin D1
chr5_-_15774729 0.97 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr7_-_41209891 0.97 ENSDART00000174300
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr1_+_1964902 0.96 ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr4_-_1346961 0.96 ENSDART00000164623
ptn
pleiotrophin
chr17_-_4160288 0.96 ENSDART00000153824
napba
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr10_+_21843488 0.95 ENSDART00000160881
pcdh1g30
protocadherin 1 gamma 30
chr4_-_25282256 0.95 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr11_-_30105047 0.92 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr7_+_9726412 0.91 ENSDART00000173155
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr4_-_5589261 0.91 ENSDART00000017349
vegfab
vascular endothelial growth factor Ab
chr25_+_16505438 0.85 ENSDART00000008986
atp6v1e1a
ATPase, H+ transporting, lysosomal, V1 subunit E1a
chr14_+_8198019 0.83 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr8_-_23744125 0.78 ENSDART00000141871
INAVA
innate immunity activator
chr21_+_11683704 0.76 ENSDART00000081646
glrx
glutaredoxin (thioltransferase)
chr10_+_20112765 0.75 ENSDART00000027612
xpo7
exportin 7
chr21_-_24552672 0.75

chr24_+_42133471 0.75 ENSDART00000170514
top1mt
topoisomerase (DNA) I, mitochondrial
chr8_+_8899112 0.74 ENSDART00000145970
si:dkey-83k24.5
si:dkey-83k24.5
chr19_+_10912601 0.72 ENSDART00000053325
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr18_+_27205666 0.71

chr2_-_49060868 0.69

chr25_-_34608926 0.67 ENSDART00000130395
hist1h4l
histone 1, H4, like
chr17_-_52493315 0.65 ENSDART00000156806
rps6kl1
ribosomal protein S6 kinase-like 1
chr25_-_13579869 0.65 ENSDART00000090226
znf319b
zinc finger protein 319b
chr5_-_51184375 0.64 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr5_+_50432868 0.63 ENSDART00000097466
fam169aa
family with sequence similarity 169, member Aa
chr6_-_2028814 0.62 ENSDART00000171265
tgm5l
transglutaminase 5, like
chr14_+_7868515 0.62 ENSDART00000167228
psd2
pleckstrin and Sec7 domain containing 2
chr8_+_6533379 0.57 ENSDART00000138135
vsig8b
V-set and immunoglobulin domain containing 8b
chr3_+_55779906 0.56

chr13_+_36554728 0.56 ENSDART00000136030
atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr10_-_41235132 0.56 ENSDART00000134851
aak1b
AP2 associated kinase 1b
chr21_+_26576104 0.53 ENSDART00000142667
esrra
estrogen-related receptor alpha
chr6_-_42143595 0.52 ENSDART00000085472
grm2a
glutamate receptor, metabotropic 2a
chr13_+_30820707 0.50 ENSDART00000057469
vstm4a
V-set and transmembrane domain containing 4a
chr7_+_8168009 0.50

chr1_+_18639896 0.50 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr7_-_24723345 0.49 ENSDART00000002961
rcor2
REST corepressor 2
chr4_-_5589227 0.49 ENSDART00000136229
vegfab
vascular endothelial growth factor Ab
chr16_+_54579976 0.48

chr12_-_1545141 0.48

chr2_-_43820397 0.47 ENSDART00000165038
FO704635.1
ENSDARG00000105141
chr9_-_24220466 0.46 ENSDART00000021218
rpe
ribulose-5-phosphate-3-epimerase
chr3_-_47294253 0.45

chr9_+_51539262 0.44

chr6_+_39523953 0.43

chr5_+_36332564 0.42 ENSDART00000037879
crx
cone-rod homeobox
chr19_+_42492029 0.40 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr2_-_11879298 0.38 ENSDART00000136748
ENSDARG00000039203
ENSDARG00000039203
chr10_-_175160 0.38

chr14_+_35029615 0.38 ENSDART00000144702
clint1a
clathrin interactor 1a
chr24_+_42133272 0.38 ENSDART00000170514
top1mt
topoisomerase (DNA) I, mitochondrial
chr9_+_21524891 0.37

chr11_-_3888456 0.36 ENSDART00000175310
ENSDART00000082404
rpn1
ribophorin I
chr15_-_19186046 0.33 ENSDART00000108818
arhgap32a
Rho GTPase activating protein 32a
chr1_-_58577305 0.32

chr18_+_41266453 0.32

chr13_+_30820765 0.32 ENSDART00000114007
ENSDART00000162254
vstm4a
V-set and transmembrane domain containing 4a
chr2_+_7260634 0.31 ENSDART00000012119
ENSDART00000153404
zgc:110366
zgc:110366
chr5_+_30690949 0.30

chr5_+_61753841 0.29

chr8_+_1016353 0.27 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr10_-_1185742 0.26 ENSDART00000114261
bmpr1bb
bone morphogenetic protein receptor, type IBb
chr3_-_47294091 0.25

chr11_+_18897913 0.25 ENSDART00000164294
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr23_-_439495 0.25 ENSDART00000146776
tspan2b
tetraspanin 2b
chr11_-_41487157 0.24 ENSDART00000173312
abhd6a
abhydrolase domain containing 6a
chr10_+_9361595 0.23 ENSDART00000136364
antxr2b
anthrax toxin receptor 2b
chr8_+_14921850 0.23 ENSDART00000138548
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr11_+_18897769 0.21 ENSDART00000163006
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr4_+_74885660 0.20 ENSDART00000164709
zgc:153116
zgc:153116
chr7_+_54336324 0.19 ENSDART00000168474
fgf3
fibroblast growth factor 3
chr14_-_6096120 0.19

chr11_-_282662 0.19 ENSDART00000168461
poc1a
POC1 centriolar protein A
chr14_-_28261949 0.19 ENSDART00000126095
insb
preproinsulin b
chr12_+_31388957 0.17

chr2_+_24851910 0.17 ENSDART00000133109
rps28
ribosomal protein S28
chr8_+_41446054 0.16 ENSDART00000061144
arpc5la
actin related protein 2/3 complex, subunit 5-like, a
chr11_-_282830 0.16 ENSDART00000173185
poc1a
POC1 centriolar protein A
KN150487v1_+_15682 0.13 ENSDART00000166996
CABZ01074304.1
ENSDARG00000100224
chr7_-_18256512 0.13 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr8_+_41446169 0.12 ENSDART00000061144
arpc5la
actin related protein 2/3 complex, subunit 5-like, a
chr18_-_6336677 0.09 ENSDART00000169844
iqsec3b
IQ motif and Sec7 domain 3b
chr12_-_7669275 0.08

chr16_+_14981032 0.07

chr20_-_4635674 0.06

chr13_-_44687273 0.05

chr16_-_10425382 0.05 ENSDART00000104025
ENSDART00000178832
flot1b
flotillin 1b
chr5_-_2540097 0.04

chr5_-_51184313 0.03 ENSDART00000159166
homer1b
homer scaffolding protein 1b
chr7_+_20829933 0.02 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr18_+_18011562 0.01 ENSDART00000005027
ENSDARG00000011498
ENSDARG00000011498

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.5 2.5 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.4 1.9 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.4 1.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.4 2.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.3 2.2 GO:0061056 sclerotome development(GO:0061056)
0.3 2.9 GO:0015671 oxygen transport(GO:0015671)
0.3 1.0 GO:0042417 dopamine metabolic process(GO:0042417)
0.2 1.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 1.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 2.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 1.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.2 0.5 GO:0019323 pentose catabolic process(GO:0019323)
0.1 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.5 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 2.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.1 GO:0070665 positive regulation of mononuclear cell proliferation(GO:0032946) positive regulation of T cell proliferation(GO:0042102) positive regulation of lymphocyte proliferation(GO:0050671) positive regulation of leukocyte proliferation(GO:0070665)
0.1 1.0 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 1.0 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 3.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.2 GO:1901998 toxin transport(GO:1901998)
0.1 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.0 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.9 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.4 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.0 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 1.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.6 GO:0006006 glucose metabolic process(GO:0006006)
0.0 2.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.2 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 1.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.4 2.9 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.4 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 1.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 4.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.8 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 1.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.5 1.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 2.9 GO:0031720 haptoglobin binding(GO:0031720)
0.4 1.9 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 3.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 1.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 1.1 GO:0033149 FFAT motif binding(GO:0033149)
0.2 0.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.2 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 1.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.4 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.0 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 4.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.0 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.7 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 3.1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
0.0 1.0 GO:0008201 heparin binding(GO:0008201)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 4.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.2 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation