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Results for irf1b+irf2+irf2a

Z-value: 2.53

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Transcription factors associated with irf1b+irf2+irf2a

Gene Symbol Gene ID Gene Info
ENSDARG00000007387 interferon regulatory factor 2a
ENSDARG00000040465 interferon regulatory factor 2
ENSDARG00000043249 interferon regulatory factor 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf2dr10_dc_chr14_-_4014025_4014033-0.879.5e-06Click!
irf2adr10_dc_chr1_+_39141680_391417460.844.7e-05Click!
txndc15dr10_dc_chr21_-_45800602_45800732-0.836.1e-05Click!

Activity profile of irf1b+irf2+irf2a motif

Sorted Z-values of irf1b+irf2+irf2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of irf1b+irf2+irf2a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_+_43868027 12.56 ENSDART00000112598
ENSDART00000169576
OTU deubiquitinase 4
chr1_-_21961282 8.42 ENSDART00000171830
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr18_-_38289370 7.68 ENSDART00000139519
cell cycle associated protein 1b
chr14_-_46980330 7.58 ENSDART00000043751
ENSDART00000141357
MACRO domain containing 1
chr11_+_1558144 7.09 ENSDART00000154583
si:dkey-40c23.2
chr1_-_44892852 6.11 ENSDART00000160961
activating transcription factor 7 interacting protein
chr6_+_38898605 5.94 ENSDART00000029930
solute carrier family 48 (heme transporter), member 1b
chr11_+_37371675 5.83 ENSDART00000140502
SH2 domain containing 5
chr20_-_20922072 5.74 ENSDART00000142618
ENSDART00000145601
creatine kinase, brain b
chr1_-_44892600 5.58 ENSDART00000149155
activating transcription factor 7 interacting protein
chr24_+_32295105 5.51 ENSDART00000143570
ENSDARG00000092965
chr3_+_32285237 5.42 ENSDART00000157324
proline rich Gla (G-carboxyglutamic acid) 2
chr1_-_55072271 5.31 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr13_-_37504883 5.16 ENSDART00000108855
si:dkey-188i13.7
chr8_-_51380691 5.13 ENSDART00000060628
charged multivesicular body protein 7
chr17_-_18777398 5.06 ENSDART00000045991
vaccinia related kinase 1
chr5_-_57053687 4.99 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr18_-_12889296 4.76 ENSDART00000130343
poly (ADP-ribose) polymerase family, member 12a
chr7_-_24724911 4.73 ENSDART00000173791
REST corepressor 2
chr4_+_16197 4.68 ENSDART00000166174
ENSDARG00000100660
chr10_-_45383207 4.66 ENSDART00000169845
poly (ADP-ribose) glycohydrolase, like
chr5_-_29782745 4.63 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr15_+_25554119 4.57 ENSDART00000162482
zgc:152863
chr13_-_6123969 4.54 ENSDART00000161163
tubulin, alpha 4 like
chr5_+_36677193 4.45 ENSDART00000159402
si:dkey-17o15.2
chr15_+_20054306 4.33 ENSDART00000155199
zgc:112083
chr3_+_51430252 4.29 ENSDART00000159493
BAI1-associated protein 2a
chr12_+_17032829 4.21 ENSDART00000028003
ankyrin repeat domain 22
chr10_-_35209022 4.18 ENSDART00000063434
receptor-interacting serine-threonine kinase 4
chr16_-_9911999 3.93 ENSDART00000154217
TAP binding protein (tapasin)-like
chr18_-_12889369 3.92 ENSDART00000130343
poly (ADP-ribose) polymerase family, member 12a
chr1_-_51567135 3.90 ENSDART00000143805
RAB3D, member RAS oncogene family, a
chr19_+_4135556 3.85 ENSDART00000162461
bloodthirsty-related gene family, member 26
chr15_-_18273640 3.84 ENSDART00000141508
bloodthirsty-related gene family, member 16
chr5_+_21902777 3.83 ENSDART00000141385
si:dkey-27p18.3
chr1_-_54505313 3.79 ENSDART00000100619
ENSDART00000163796
zgc:158803
chr24_-_31967674 3.74 ENSDART00000156060
si:ch73-78o10.1
chr21_+_31216418 3.73 ENSDART00000178521
argininosuccinate lyase
chr10_-_210594 3.71 ENSDART00000059476
proteasome (prosome, macropain) assembly chaperone 1
chr12_+_17032997 3.71 ENSDART00000028003
ankyrin repeat domain 22
chr2_+_36623514 3.65 ENSDART00000098415
inhibitor of growth family, member 5b
chr11_+_36088518 3.61

chr8_-_14042703 3.59 ENSDART00000042867
death effector domain containing
chr23_+_32015527 3.59 ENSDART00000088607
nuclear envelope integral membrane protein 1
chr24_+_32295150 3.57 ENSDART00000143570
ENSDARG00000092965
chr22_-_7431710 3.54 ENSDART00000170630
ENSDARG00000104176
chr22_+_31073990 3.47 ENSDART00000111561
zmp:0000000735
chr14_+_9175399 3.47 ENSDART00000054690
ENSDART00000135449
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr3_+_12087549 3.45

chr5_+_36168475 3.45 ENSDART00000146854
MAP/microtubule affinity-regulating kinase 4a
chr16_-_40508858 3.44 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr22_-_7780120 3.35 ENSDART00000097201
si:ch73-44m9.1
chr22_-_7412566 3.35 ENSDART00000161615
ENSDART00000158210
ENSDARG00000099295
chr10_-_7862983 3.35 ENSDART00000160606
ENSDART00000112201
methionine adenosyltransferase II, alpha a
chr2_+_10040130 3.32 ENSDART00000139639
annexin A13, like
chr19_-_35905513 3.28 ENSDART00000177052
protein tyrosine phosphatase type IVA, member 2b
chr22_+_30041252 3.24 ENSDART00000165313
si:dkey-286j15.3
chr13_-_49886891 3.21 ENSDART00000074230
protein kinase containing Z-DNA binding domains
chr22_-_7976467 3.21 ENSDART00000162028
sc:d217
chr21_-_31215463 3.19 ENSDART00000170507
calcitonin gene-related peptide-receptor component protein
chr9_+_30815655 3.16 ENSDART00000147813
TBC1 domain family, member 4
chr6_-_1613740 3.00 ENSDART00000156305
tripartite motif containing 107
chr2_+_35621136 2.99 ENSDART00000133018
ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr3_-_21006698 2.97 ENSDART00000104051
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr7_+_55217087 2.95 ENSDART00000149915
chromatin licensing and DNA replication factor 1
chr15_+_20416591 2.92 ENSDART00000161047
interleukin 15, like
chr5_-_29782945 2.85 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr18_-_23847383 2.84 ENSDART00000155068
ENSDARG00000097764
KN150200v1_-_6975 2.77

chr5_+_57056091 2.75 ENSDART00000134684
ferredoxin-fold anticodon binding domain containing 1
chr7_+_66660882 2.73 ENSDART00000082664
SET binding factor 2
chr1_-_54505112 2.72 ENSDART00000100619
ENSDART00000163796
zgc:158803
chr6_+_36862078 2.68 ENSDART00000104160
ENSDARG00000070746
chr13_+_2345595 2.68

chr5_-_29782972 2.66 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr9_-_23954640 2.65 ENSDART00000027212
ENSDARG00000006848
chr15_+_20416518 2.64 ENSDART00000161047
interleukin 15, like
chr12_-_4800362 2.64 ENSDART00000172093
si:ch211-93e11.8
chr2_-_21512154 2.63 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr23_+_33792145 2.63 ENSDART00000024695
DAZ associated protein 2
chr11_-_44734403 2.61 ENSDART00000160656
arylformamidase
chr3_-_39117855 2.56 ENSDART00000102678
N-myristoyltransferase 1a
chr9_+_22015827 2.55 ENSDART00000101985
zgc:162944
chr5_+_27697056 2.54 ENSDART00000132070
vesicle-associated membrane protein 5
chr1_-_44892558 2.53 ENSDART00000149155
activating transcription factor 7 interacting protein
chr22_-_8144599 2.52 ENSDART00000156571
si:ch73-44m9.3
chr15_-_1519615 2.52 ENSDART00000129356
si:dkeyp-97b10.3
chr13_+_11418060 2.51 ENSDART00000166908
desumoylating isopeptidase 2
chr6_+_49054117 2.50 ENSDART00000011876
synaptonemal complex protein 1
chr15_-_29229170 2.49 ENSDART00000138449
XIAP associated factor 1
chr19_+_38580804 2.49 ENSDART00000160756
PHD finger protein 14
chr17_-_42523585 2.47 ENSDART00000154755
protein kinase D3
chr24_+_16838877 2.47 ENSDART00000145520
eukaryotic translation initiation factor 2, subunit 3 gamma
chr5_-_23092592 2.46 ENSDART00000024815
family with sequence similarity 76, member B
chr2_-_26820425 2.45 ENSDART00000132125
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr12_-_37274632 2.45 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr10_-_25366450 2.44 ENSDART00000123820
transmembrane protein 135
chr14_+_36074512 2.44 ENSDART00000015761
nei-like DNA glycosylase 3
chr3_-_19890717 2.44 ENSDART00000104118
ENSDART00000170199
ataxin 7-like 3
chr3_+_32530476 2.42 ENSDART00000171556
si:dkey-16l2.16
chr10_+_35209025 2.42 ENSDART00000126105
NOP2/Sun domain family, member 5
chr13_+_7055611 2.39 ENSDART00000148240
exocyst complex component 3-like 4
chr12_+_1247340 2.37

chr11_-_36088336 2.37 ENSDART00000141477
proteasome subunit alpha 5
chr18_-_23847340 2.37 ENSDART00000155068
ENSDARG00000097764
chr7_-_69883542 2.36

KN150335v1_-_25856 2.31 ENSDART00000164352
zgc:171497
chr12_-_26468261 2.31 ENSDART00000039510
si:dkey-57h18.2
chr12_+_17032963 2.30 ENSDART00000028003
ankyrin repeat domain 22
chr17_-_25612341 2.30 ENSDART00000126201
ENSDART00000105503
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr6_+_12810986 2.29 ENSDART00000104757
ENSDART00000165896
caspase 8, apoptosis-related cysteine peptidase
chr15_+_14656645 2.28 ENSDART00000162350
F-box protein 46
chr4_-_26106485 2.26 ENSDART00000100611
si:ch211-244b2.3
chr9_+_8919663 2.26 ENSDART00000134954
carbohydrate kinase domain containing
chr9_-_41151768 2.23 ENSDART00000135805
ENSDARG00000092912
chr23_+_38228263 2.22 ENSDART00000137969
zgc:112994
chr21_+_20286289 2.21 ENSDART00000153992
ENSDART00000156867
ENSDARG00000096964
chr15_+_17162691 2.20

chr13_+_26573404 2.20 ENSDART00000142483
Fanconi anemia, complementation group L
chr24_-_34794538 2.20 ENSDART00000171009
ENSDART00000170046
catenin (cadherin-associated protein), alpha 1
chr7_-_69883581 2.17

chr24_+_32295048 2.17 ENSDART00000143570
ENSDARG00000092965
chr6_-_1613915 2.16 ENSDART00000112118
tripartite motif containing 107
chr5_+_57056176 2.16 ENSDART00000134684
ferredoxin-fold anticodon binding domain containing 1
chr25_-_25455861 2.15 ENSDART00000150412
interferon regulatory factor 7
chr20_+_29328615 2.15 ENSDART00000147064
apoptosis, caspase activation inhibitor
chr6_-_54425831 2.12 ENSDART00000017230
small nuclear ribonucleoprotein polypeptide C
chr16_-_9562744 2.11 ENSDART00000126154
PRP3 pre-mRNA processing factor 3 homolog (yeast)
chr7_-_71343686 2.11 ENSDART00000128678
methyltransferase like 4
chr15_-_29229135 2.10 ENSDART00000138449
XIAP associated factor 1
chr16_+_14119938 2.09 ENSDART00000059928
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
chr5_-_57053661 2.09 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr22_-_34639168 2.09

chr8_-_21020134 2.09 ENSDART00000136561
si:dkeyp-82a1.6
chr12_-_4563094 2.08 ENSDART00000152489
interferon regulatory factor 3
chr9_+_29806055 2.08 ENSDART00000143493
PHD finger protein 11
chr1_-_51567283 2.06 ENSDART00000023757
RAB3D, member RAS oncogene family, a
chr17_-_42523635 2.06 ENSDART00000154755
protein kinase D3
chr9_-_40881885 2.03 ENSDART00000141979
BRCA1 associated RING domain 1
chr5_+_40235387 2.03 ENSDART00000147767
si:dkey-3h3.3
chr24_-_13205000 2.02 ENSDART00000134482
telomeric repeat binding factor (NIMA-interacting) 1
chr4_-_19911139 2.02

chr6_-_1613994 2.02 ENSDART00000112118
tripartite motif containing 107
chr25_-_19476079 2.01 ENSDART00000156811
si:ch211-59o9.10
chr18_-_38289008 2.01 ENSDART00000139519
cell cycle associated protein 1b
chr13_+_11417882 2.00 ENSDART00000034935
desumoylating isopeptidase 2
chr11_+_39664664 2.00 ENSDART00000102734
ENSDART00000137516
vesicle-associated membrane protein 3 (cellubrevin)
chr22_-_7887341 1.99 ENSDART00000097198
sc:d217
chr23_-_36350571 1.98 ENSDART00000110478
zgc:174906
chr20_+_44684340 1.98 ENSDART00000149775
ATPase family, AAA domain containing 2B
chr16_-_31834774 1.97

chr7_+_19348229 1.97 ENSDART00000007310
ENSDART00000166355
zgc:171731
chr14_+_31278584 1.96 ENSDART00000158875
ENSDART00000026195
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6a
chr25_-_27222696 1.95 ENSDART00000123590
si:ch211-91p5.3
chr10_+_21487218 1.93 ENSDART00000147215
ENSDART00000019252
F-box and WD repeat domain containing 11b
chr5_+_69007907 1.92 ENSDART00000154507
si:ch211-275j6.5
chr13_-_40592360 1.91

chr5_-_56953716 1.91 ENSDART00000167892
zgc:193711
chr7_-_40307611 1.90 ENSDART00000173926
ENSDART00000010035
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr23_-_36350288 1.90 ENSDART00000110478
zgc:174906
chr18_-_14910429 1.90 ENSDART00000099701
selenoprotein O
chr3_+_1054368 1.88 ENSDART00000153693
si:ch73-166o21.1
chr5_-_56953587 1.88 ENSDART00000167892
zgc:193711
chr5_+_44204845 1.87 ENSDART00000141198
cathepsin La
chr18_+_14715573 1.87 ENSDART00000108469
spermatogenesis associated 2-like
chr15_-_16447990 1.86 ENSDART00000154504
family with sequence similarity 222, member Bb
chr14_+_11864388 1.86 ENSDART00000146521
ras homolog gene family, member Gd
chr2_-_8813671 1.86 ENSDART00000138223
si:ch211-71m22.1
chr9_-_35824470 1.85 ENSDART00000140356
zona pellucida glycoprotein 2, like 1
chr5_+_32215942 1.84 ENSDART00000047377
carnitine O-acetyltransferase a
chr10_-_21971084 1.84 ENSDART00000174954
ENSDARG00000107280
chr5_+_45295180 1.84 ENSDART00000083937
polymerase (DNA directed) kappa
chr11_-_40239946 1.83 ENSDART00000165394
si:dkeyp-61b2.1
chr10_-_7862767 1.83 ENSDART00000059021
methionine adenosyltransferase II, alpha a
chr21_+_19283166 1.76 ENSDART00000063621
abraxas 2a, BRISC complex subunit
chr8_-_51380846 1.76 ENSDART00000060628
charged multivesicular body protein 7
chr1_-_529071 1.75 ENSDART00000147610
si:ch73-41e3.7
chr22_+_2049719 1.74

chr14_+_11863984 1.74 ENSDART00000129953
ras homolog gene family, member Gd
chr16_+_17762256 1.73 ENSDART00000128672
transmembrane protein 238b
chr23_-_45011264 1.72 ENSDART00000129138
monoacylglycerol O-acyltransferase 3a
chr5_-_5848617 1.71

chr18_+_13280400 1.70 ENSDART00000080709
phospholipase C, gamma 2
chr5_+_44204661 1.69 ENSDART00000122288
cathepsin La
chr21_-_21477462 1.69 ENSDART00000031205
poliovirus receptor-related 3b
chr8_+_47108614 1.68 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr13_-_33096999 1.68 ENSDART00000057386
golgin A5
chr16_-_40508938 1.67 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr19_-_34529880 1.66 ENSDART00000158677
ENSDART00000112004
si:dkey-184p18.2
chr1_+_22798407 1.66 ENSDART00000134576
si:dkeyp-26a9.2
chr14_+_11863939 1.63 ENSDART00000129953
ras homolog gene family, member Gd
chr19_+_15581145 1.63 ENSDART00000079014
PDLIM1 interacting kinase 1 like
chr15_-_14147062 1.63 ENSDART00000147796
trafficking protein particle complex 6b-like
chr4_-_12979951 1.61 ENSDART00000013839
transmembrane BAX inhibitor motif containing 4
chr13_+_17564330 1.59 ENSDART00000079778
interferon-induced protein with tetratricopeptide repeats 8
chr9_-_34450885 1.59 ENSDART00000012385
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr12_-_20494169 1.58 ENSDART00000105362
sorting nexin 11
chr2_-_21512285 1.58 ENSDART00000135417
bmi1 polycomb ring finger oncogene 1b
chr2_-_8813612 1.57 ENSDART00000138223
si:ch211-71m22.1
chr9_-_23954690 1.57 ENSDART00000027212
ENSDARG00000006848

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
2.9 8.7 GO:0090166 Golgi disassembly(GO:0090166)
1.2 14.7 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.1 6.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.0 6.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
1.0 1.0 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.9 3.6 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.9 3.5 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.8 2.5 GO:0051026 chiasma assembly(GO:0051026)
0.8 2.3 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism(GO:0043903) interaction with host(GO:0051701)
0.8 3.0 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.7 5.7 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.7 2.9 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.7 2.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.7 2.0 GO:0019376 galactosylceramide catabolic process(GO:0006683) galactolipid catabolic process(GO:0019376)
0.7 7.3 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.6 2.6 GO:0018008 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.6 2.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.6 2.5 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791) medium-chain fatty acid catabolic process(GO:0051793)
0.6 3.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6 8.3 GO:0070475 rRNA base methylation(GO:0070475)
0.5 2.2 GO:2000737 negative regulation of stem cell differentiation(GO:2000737)
0.5 4.3 GO:2000251 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.5 2.1 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.5 6.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 7.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 1.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.4 1.3 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.4 3.7 GO:0006591 ornithine metabolic process(GO:0006591)
0.4 2.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 2.4 GO:0051601 exocyst localization(GO:0051601)
0.4 5.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 1.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.4 4.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.4 1.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 3.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 1.3 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.3 5.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.3 3.5 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.3 3.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.3 1.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.3 3.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.3 1.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.2 1.9 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.2 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.9 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 1.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 3.6 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.2 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 3.5 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.2 6.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 2.7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 5.1 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 4.7 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.2 3.8 GO:0009395 phospholipid catabolic process(GO:0009395)
0.2 4.8 GO:0051607 defense response to virus(GO:0051607)
0.1 1.9 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 4.0 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.1 13.1 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 3.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.5 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.1 0.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.0 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 2.2 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 2.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.9 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 0.6 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.6 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.9 GO:0072078 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.1 9.6 GO:0017148 negative regulation of translation(GO:0017148)
0.1 1.0 GO:0008272 sulfate transport(GO:0008272)
0.1 1.7 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 1.5 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.6 GO:0099633 protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.1 1.0 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 0.9 GO:0007020 microtubule nucleation(GO:0007020)
0.1 4.7 GO:0016575 histone deacetylation(GO:0016575)
0.1 1.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 1.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.1 0.2 GO:2000058 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.1 0.6 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.1 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.7 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.4 GO:0032456 endocytic recycling(GO:0032456)
0.1 2.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 2.5 GO:0051028 mRNA transport(GO:0051028)
0.1 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 4.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 1.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 21.1 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.5 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:1903201 regulation of cellular response to oxidative stress(GO:1900407) negative regulation of cellular response to oxidative stress(GO:1900408) negative regulation of response to oxidative stress(GO:1902883) regulation of oxidative stress-induced cell death(GO:1903201) negative regulation of oxidative stress-induced cell death(GO:1903202)
0.0 0.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 2.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.9 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.8 GO:0007254 JNK cascade(GO:0007254)
0.0 0.2 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.9 GO:0007031 peroxisome organization(GO:0007031)
0.0 2.0 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.1 GO:0071265 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.5 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.6 GO:0051321 meiotic cell cycle(GO:0051321)
0.0 0.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 3.5 GO:0042278 purine nucleoside metabolic process(GO:0042278)
0.0 1.1 GO:0000819 sister chromatid segregation(GO:0000819)
0.0 1.0 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.2 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 3.5 GO:0000278 mitotic cell cycle(GO:0000278)
0.0 4.4 GO:0008380 RNA splicing(GO:0008380)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.0 GO:0001894 tissue homeostasis(GO:0001894)
0.0 1.2 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:0071560 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.6 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.3 GO:0099518 vesicle cytoskeletal trafficking(GO:0099518)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.8 2.5 GO:0000801 central element(GO:0000801)
0.6 7.1 GO:0000815 ESCRT III complex(GO:0000815)
0.5 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.5 6.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.4 1.3 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.4 2.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 2.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 4.0 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.2 2.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 4.7 GO:0030057 desmosome(GO:0030057)
0.2 0.9 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.2 5.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 1.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 2.4 GO:0000145 exocyst(GO:0000145)
0.2 8.6 GO:0031901 early endosome membrane(GO:0031901)
0.2 4.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.7 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 3.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 4.3 GO:0030175 filopodium(GO:0030175)
0.1 1.5 GO:0000243 commitment complex(GO:0000243)
0.1 0.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 3.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 5.8 GO:0014069 postsynaptic density(GO:0014069)
0.1 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.1 6.9 GO:0005795 Golgi stack(GO:0005795)
0.1 4.5 GO:0031201 SNARE complex(GO:0031201)
0.1 4.6 GO:0000922 spindle pole(GO:0000922)
0.1 10.5 GO:0010008 endosome membrane(GO:0010008)
0.1 5.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 4.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.1 0.3 GO:0031526 brush border membrane(GO:0031526)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0030880 RNA polymerase complex(GO:0030880)
0.0 1.0 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 3.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 3.5 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 7.3 GO:0005730 nucleolus(GO:0005730)
0.0 3.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.4 GO:0005774 vacuolar membrane(GO:0005774)
0.0 1.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 6.6 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0070042 rRNA (uridine-N3-)-methyltransferase activity(GO:0070042)
1.2 3.5 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.2 12.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
1.0 6.0 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.9 3.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.9 25.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.9 3.6 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.9 3.5 GO:0004061 arylformamidase activity(GO:0004061)
0.8 2.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.7 5.7 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.7 2.0 GO:0004336 galactosylceramidase activity(GO:0004336)
0.7 7.3 GO:0015232 heme transporter activity(GO:0015232)
0.6 3.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.6 2.6 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.6 1.8 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.6 3.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.5 1.6 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 2.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.4 3.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 1.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.4 2.5 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.4 1.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 1.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 3.0 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 3.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.3 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 2.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 2.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 4.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.2 1.2 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.7 GO:0035197 siRNA binding(GO:0035197)
0.2 3.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 1.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 4.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 6.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 3.8 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.2 1.0 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.2 1.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 2.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 3.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 12.9 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 1.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 3.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 4.7 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.9 GO:0070628 proteasome binding(GO:0070628)
0.1 1.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 1.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 3.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.2 GO:0047522 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 3.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.1 3.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 2.5 GO:0000049 tRNA binding(GO:0000049)
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 21.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 6.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 4.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 3.4 GO:0000149 SNARE binding(GO:0000149)
0.0 1.9 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 6.1 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 8.7 GO:0003924 GTPase activity(GO:0003924)
0.0 1.7 GO:0042802 identical protein binding(GO:0042802)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.4 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.5 8.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 5.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 4.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 3.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 6.6 PID P73PATHWAY p73 transcription factor network
0.1 1.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.6 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 7.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.3 3.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 2.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 4.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.2 3.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 4.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 3.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 6.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 2.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 3.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 3.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.0 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives