Project
DANIO-CODE
Navigation
Downloads
Results for irf5
Z-value: 2.42
Motif logo
Transcription factors associated with irf5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| irf5 | dr10_dc_chr4_-_13615927_13616074 | 0.77 | 5.5e-04 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of irf5
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_32937536 Show fit | 6.40 |
ENSDART00000132850
|
START domain containing 14 |
|
| chr1_-_55072271 Show fit | 5.67 |
ENSDART00000142244
|
DnaJ (Hsp40) homolog, subfamily B, member 1b |
|
| chr14_-_32937496 Show fit | 5.34 |
ENSDART00000048130
|
START domain containing 14 |
|
| chr15_-_34106827 Show fit | 5.31 |
ENSDART00000163841
|
lipolysis stimulated lipoprotein receptor |
|
| chr14_+_32578103 Show fit | 5.20 |
ENSDART00000105721
|
ligand of numb-protein X 2b |
|
| chr7_+_68964813 Show fit | 5.20 |
ENSDART00000166258
|
MARVEL domain containing 3 |
|
| chr22_+_24596299 Show fit | 5.17 |
ENSDART00000158303
ENSDART00000160924 |
mucolipin 2 |
|
| chr14_+_32578253 Show fit | 4.86 |
ENSDART00000105721
|
ligand of numb-protein X 2b |
|
| chr16_+_19831573 Show fit | 4.62 |
ENSDART00000135359
|
metastasis associated in colon cancer 1 |
|
| chr10_-_22180658 Show fit | 4.54 |
ENSDART00000006173
|
claudin 7b |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 19.7 | GO:0060876 | semicircular canal formation(GO:0060876) |
| 0.3 | 10.1 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 7.9 | GO:0008544 | epidermis development(GO:0008544) |
| 0.0 | 7.5 | GO:0016567 | protein ubiquitination(GO:0016567) |
| 0.2 | 6.9 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 6.8 | GO:0001894 | tissue homeostasis(GO:0001894) |
| 0.0 | 5.3 | GO:0031016 | pancreas development(GO:0031016) |
| 0.1 | 5.2 | GO:0046890 | regulation of lipid biosynthetic process(GO:0046890) |
| 0.3 | 4.7 | GO:0045176 | asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176) |
| 0.1 | 4.5 | GO:0000082 | G1/S transition of mitotic cell cycle(GO:0000082) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 27.6 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.3 | 6.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.4 | 5.5 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 5.4 | GO:0005764 | lysosome(GO:0005764) |
| 0.0 | 5.1 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.8 | 4.5 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
| 0.1 | 4.3 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 4.1 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 3.8 | GO:0030496 | midbody(GO:0030496) |
| 0.6 | 3.6 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 18.0 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 17.3 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 13.8 | GO:0008289 | lipid binding(GO:0008289) |
| 0.3 | 8.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 8.6 | GO:0004672 | protein kinase activity(GO:0004672) |
| 0.4 | 6.9 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.2 | 6.4 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.1 | 5.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.6 | 5.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.0 | 5.5 | GO:0051015 | actin filament binding(GO:0051015) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.4 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.3 | 4.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 4.3 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 2.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 2.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 2.3 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 2.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.2 | 1.5 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.1 | 1.0 | PID ARF6 PATHWAY | Arf6 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 8.0 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.3 | 6.4 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 4.7 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.2 | 4.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 1.1 | 4.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 4.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 3.8 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 3.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.4 | 2.9 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 2.3 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |