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Results for irf5

Z-value: 2.42

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Transcription factors associated with irf5

Gene Symbol Gene ID Gene Info
irf5
ENSDARG00000045681 interferon regulatory factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf5dr10_dc_chr4_-_13615927_136160740.775.5e-04Click!

Activity profile of irf5 motif

Sorted Z-values of irf5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of irf5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_32937536 6.40 ENSDART00000132850
stard14
START domain containing 14
chr1_-_55072271 5.67 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr14_-_32937496 5.34 ENSDART00000048130
stard14
START domain containing 14
chr15_-_34106827 5.31 ENSDART00000163841
lsr
lipolysis stimulated lipoprotein receptor
chr14_+_32578103 5.20 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr7_+_68964813 5.20 ENSDART00000166258
marveld3
MARVEL domain containing 3
chr22_+_24596299 5.17 ENSDART00000158303
ENSDART00000160924
mcoln2
mucolipin 2
chr14_+_32578253 4.86 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr16_+_19831573 4.62 ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr10_-_22180658 4.54 ENSDART00000006173
cldn7b
claudin 7b
chr9_-_23954640 4.47 ENSDART00000027212
ENSDARG00000006848
ENSDARG00000006848
chr20_+_6545449 4.34 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr10_-_35209022 4.24 ENSDART00000063434
ripk4
receptor-interacting serine-threonine kinase 4
chr10_-_22180530 4.08 ENSDART00000006173
cldn7b
claudin 7b
chr18_+_45669615 4.07 ENSDART00000150973
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr18_+_44538877 4.07 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr5_-_29782745 4.06 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr1_-_54505313 4.02 ENSDART00000100619
ENSDART00000163796
LUC7L2
zgc:158803
chr18_+_44539099 3.84 ENSDART00000140672
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr10_-_22180935 3.83 ENSDART00000006173
cldn7b
claudin 7b
chr5_-_28931727 3.76 ENSDART00000174697
arrdc1a
arrestin domain containing 1a
chr12_+_17032829 3.73 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr15_+_44177774 3.67

chr13_-_22921202 3.61 ENSDART00000111774
supv3l1
SUV3-like helicase
chr10_-_33435736 3.58 ENSDART00000023509
ska2
spindle and kinetochore associated complex subunit 2
chr15_+_22458649 3.54 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr22_-_17663766 3.53 ENSDART00000147070
tjp3
tight junction protein 3
chr13_-_37504883 3.53 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
KN149966v1_+_102652 3.52 ENSDART00000160223
CABZ01062996.1
ENSDARG00000102332
chr15_-_29229170 3.44 ENSDART00000138449
xaf1
XIAP associated factor 1
chr20_-_22170411 3.41 ENSDART00000155568
BX088688.3
ENSDARG00000097598
chr20_+_35156812 3.39

chr14_-_32937341 3.39 ENSDART00000048130
stard14
START domain containing 14
chr1_-_54505112 3.38 ENSDART00000100619
ENSDART00000163796
LUC7L2
zgc:158803
chr15_+_44177693 3.31

chr12_+_17032997 3.28 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr15_-_29229135 3.14 ENSDART00000138449
xaf1
XIAP associated factor 1
chr6_+_30385355 3.14 ENSDART00000108943
shroom2a
shroom family member 2a
chr10_-_22180856 3.09 ENSDART00000006173
cldn7b
claudin 7b
chr15_+_44160948 3.04 ENSDART00000110060
zgc:165514
zgc:165514
chr20_+_3386573 2.96 ENSDART00000175369
ENSDART00000176963
ENSDART00000176191
CABZ01061478.1
ENSDARG00000106218
chr24_+_39285121 2.95

chr9_-_30453581 2.92 ENSDART00000060150
mid1ip1a
MID1 interacting protein 1a
chr24_-_34794538 2.92 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr22_-_7431710 2.92 ENSDART00000170630
BX511034.7
ENSDARG00000104176
chr21_+_20974216 2.90 ENSDART00000079692
ndr1
nodal-related 1
chr20_+_6545194 2.83 ENSDART00000159829
si:ch211-191a24.4
si:ch211-191a24.4
chr9_-_23954690 2.74 ENSDART00000027212
ENSDARG00000006848
ENSDARG00000006848
chr10_-_25366450 2.74 ENSDART00000123820
tmem135
transmembrane protein 135
chr5_-_37655292 2.73 ENSDART00000156291
CT025690.1
ENSDARG00000096962
chr6_-_1613740 2.70 ENSDART00000156305
trim107
tripartite motif containing 107
chr6_-_33931989 2.64 ENSDART00000141483
nasp
nuclear autoantigenic sperm protein (histone-binding)
chr2_-_21780380 2.60 ENSDART00000144587
plcd1b
phospholipase C, delta 1b
chr5_+_32687543 2.59 ENSDART00000123210
med22
mediator complex subunit 22
chr25_+_15983733 2.58 ENSDART00000165598
ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr19_-_15516318 2.58 ENSDART00000151454
serinc2
serine incorporator 2
chr23_+_32015527 2.56 ENSDART00000088607
nemp1
nuclear envelope integral membrane protein 1
chr6_-_10492724 2.53 ENSDART00000002247
sp3b
Sp3b transcription factor
chr10_-_22180791 2.44 ENSDART00000006173
cldn7b
claudin 7b
chr25_+_28419390 2.44 ENSDART00000154681
si:ch211-106e7.2
si:ch211-106e7.2
chr9_-_23954761 2.43 ENSDART00000027212
ENSDARG00000006848
ENSDARG00000006848
chr20_-_43846604 2.41 ENSDART00000150078
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr5_-_29782945 2.37 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr7_-_69576270 2.35

chr19_+_42657913 2.33 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr22_+_32281360 2.33 ENSDART00000114531
ENSDART00000136125
rbm15b
RNA binding motif protein 15B
chr15_+_34106908 2.33

chr6_+_49772891 2.32 ENSDART00000134207
ctsz
cathepsin Z
chr7_+_45748011 2.32 ENSDART00000170294
ccne1
cyclin E1
chr15_+_25516764 2.30 ENSDART00000009545
pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr15_-_1519615 2.30 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3
chr5_-_29782972 2.29 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr7_-_55879342 2.26 ENSDART00000098438
spg7
spastic paraplegia 7
chr7_-_19116856 2.26 ENSDART00000165680
ntn4
netrin 4
chr21_+_1719308 2.26

KN149855v1_+_17122 2.26 ENSDART00000162455
ENSDART00000157851
CABZ01109021.1
ENSDARG00000100904
chr10_-_20524937 2.24

chr20_+_3386522 2.23 ENSDART00000175369
ENSDART00000176963
ENSDART00000176191
CABZ01061478.1
ENSDARG00000106218
chr23_-_10810190 2.23 ENSDART00000140745
eif4e3
eukaryotic translation initiation factor 4E family member 3
chr7_+_45748086 2.22 ENSDART00000170294
ccne1
cyclin E1
chr23_-_31339986 2.22 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr4_+_20093671 2.18 ENSDART00000066961
ppp6r2a
protein phosphatase 6, regulatory subunit 2a
chr7_-_69576406 2.17

chr6_-_39162916 2.17 ENSDART00000148661
stat2
signal transducer and activator of transcription 2
chr24_-_34794856 2.15 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr5_+_44204845 2.15 ENSDART00000141198
ctsla
cathepsin La
chr14_+_50010976 2.15 ENSDART00000171955
CR855307.1
ENSDARG00000099628
chr9_+_23954807 2.14 ENSDART00000145120
ENSDARG00000040445
ENSDARG00000040445
chr25_-_27222696 2.12 ENSDART00000123590
si:ch211-91p5.3
si:ch211-91p5.3
chr21_-_22507089 2.11 ENSDART00000177084
myo5b
myosin VB
chr5_+_44204661 2.10 ENSDART00000122288
ctsla
cathepsin La
chr19_+_5052459 2.09 ENSDART00000003634
stard3
StAR-related lipid transfer (START) domain containing 3
chr9_+_42656327 2.07

chr9_+_38715293 2.06 ENSDART00000131846
osbpl11
oxysterol binding protein-like 11
chr13_-_24778352 2.05

chr18_-_44539130 2.04

chr15_+_25516962 2.04 ENSDART00000165509
pak4
p21 protein (Cdc42/Rac)-activated kinase 4
chr2_+_38042821 2.02 ENSDART00000134211
ENSDART00000144868
hnrnpc
heterogeneous nuclear ribonucleoprotein C
KN150702v1_-_111659 2.02 ENSDART00000165431
PPP1CC
protein phosphatase 1 catalytic subunit gamma
chr15_+_22458952 2.01 ENSDART00000109931
oafa
OAF homolog a (Drosophila)
chr25_+_15901398 2.00 ENSDART00000140047
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr21_-_22085596 1.96 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr7_-_69576628 1.92

chr4_-_17680826 1.89 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr7_-_29956782 1.89 ENSDART00000173514
znf710b
zinc finger protein 710b
chr12_+_17032963 1.88 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr3_-_55399158 1.87 ENSDART00000162413
axin2
axin 2 (conductin, axil)
chr7_-_73897752 1.83 ENSDART00000164874
cldnd1a
claudin domain containing 1a
chr12_-_16403282 1.82 ENSDART00000037601
rpp30
ribonuclease P/MRP 30 subunit
chr5_+_56772028 1.81 ENSDART00000097395
prpf4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr10_-_2944190 1.77 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr5_+_32687626 1.76 ENSDART00000146759
med22
mediator complex subunit 22
chr21_+_37985536 1.74 ENSDART00000085728
klf8
Kruppel-like factor 8
KN150384v1_+_17709 1.74

chr15_+_32053944 1.74 ENSDART00000175828
brca2
breast cancer 2, early onset
chr14_-_25636795 1.73

chr23_-_31340025 1.72 ENSDART00000139746
si:dkey-261l7.2
si:dkey-261l7.2
chr6_-_1613994 1.72 ENSDART00000112118
trim107
tripartite motif containing 107
chr10_-_22181059 1.70 ENSDART00000006173
cldn7b
claudin 7b
chr11_-_3313199 1.69 ENSDART00000002545
mcrs1
microspherule protein 1
chr6_-_1613915 1.69 ENSDART00000112118
trim107
tripartite motif containing 107
chr10_+_35209025 1.67 ENSDART00000126105
nsun5
NOP2/Sun domain family, member 5
chr14_-_32937838 1.67 ENSDART00000132850
stard14
START domain containing 14
chr10_+_110941 1.64 ENSDART00000135572
pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr22_+_18294579 1.62 ENSDART00000033103
gatad2ab
GATA zinc finger domain containing 2Ab
chr9_+_23954669 1.57 ENSDART00000145120
ENSDARG00000040445
ENSDARG00000040445
chr19_+_42658184 1.57 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr20_-_43846553 1.56 ENSDART00000150078
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr10_-_15921335 1.55 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr20_-_30132167 1.54 ENSDART00000033588
BX248324.1
ENSDARG00000024870
chr9_+_41657971 1.54 ENSDART00000132501
nemp2
nuclear envelope integral membrane protein 2
chr22_+_18294622 1.51 ENSDART00000033103
gatad2ab
GATA zinc finger domain containing 2Ab
chr9_-_30453625 1.50 ENSDART00000060150
mid1ip1a
MID1 interacting protein 1a
chr5_+_44205128 1.50 ENSDART00000136965
ctsla
cathepsin La
chr17_+_30877631 1.50 ENSDART00000127996
degs2
delta(4)-desaturase, sphingolipid 2
chr4_-_20501289 1.49 ENSDART00000132464
gsap
gamma-secretase activating protein
chr6_+_48349630 1.48 ENSDART00000064826
mov10a
Mov10 RISC complex RNA helicase a
chr5_+_57784991 1.47 ENSDART00000038602
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr13_+_24132617 1.44 ENSDART00000135992
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr8_+_30998992 1.44 ENSDART00000129882
ptgesl
prostaglandin E synthase 2-like
chr12_+_26970745 1.44 ENSDART00000153426
srcap
Snf2-related CREBBP activator protein
chr21_+_19283166 1.43 ENSDART00000063621
abraxas2a
abraxas 2a, BRISC complex subunit
chr12_-_1435708 1.42

chr13_+_17564330 1.41 ENSDART00000079778
ifit8
interferon-induced protein with tetratricopeptide repeats 8
chr8_+_18509772 1.40 ENSDART00000089274
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr22_-_6970664 1.39

chr10_-_2944295 1.38 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr9_+_23192282 1.37 ENSDART00000021060
eaf2
ELL associated factor 2
chr16_+_26727466 1.35 ENSDART00000087537
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr13_-_24132195 1.33

chr13_-_33348231 1.33 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr24_-_34794463 1.31 ENSDART00000171009
ENSDART00000170046
ctnna1
catenin (cadherin-associated protein), alpha 1
chr18_+_45711856 1.30 ENSDART00000077341
depdc7
DEP domain containing 7
chr13_-_49886891 1.29 ENSDART00000074230
pkz
protein kinase containing Z-DNA binding domains
chr4_-_66538843 1.29 ENSDART00000165173
BX548011.1
ENSDARG00000103357
chr19_+_1743359 1.28 ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr12_-_33704272 1.26 ENSDART00000030566
galk1
galactokinase 1
chr19_-_10295398 1.24 ENSDART00000148225
znf865
zinc finger protein 865
chr4_+_18525469 1.23 ENSDART00000154154
BX649398.1
ENSDARG00000097195
chr7_-_20593964 1.21 ENSDART00000135509
fis1
fission, mitochondrial 1
chr16_-_41716834 1.20 ENSDART00000084528
atp2c1
ATPase, Ca++ transporting, type 2C, member 1
chr23_-_10810264 1.18 ENSDART00000013768
eif4e3
eukaryotic translation initiation factor 4E family member 3
chr5_-_37655165 1.18 ENSDART00000156291
CT025690.1
ENSDARG00000096962
chr8_+_30999182 1.17 ENSDART00000129882
ptgesl
prostaglandin E synthase 2-like
chr21_-_42813859 1.16

chr10_+_9576840 1.15 ENSDART00000080843
ndufa8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8
chr12_-_33704313 1.15 ENSDART00000030566
galk1
galactokinase 1
chr9_+_23954607 1.12 ENSDART00000145120
ENSDARG00000040445
ENSDARG00000040445
chr14_+_623802 1.11 ENSDART00000169624
zgc:158257
zgc:158257
chr5_-_12586284 1.10 ENSDART00000051664
ypel1
yippee-like 1
chr25_+_8370452 1.09 ENSDART00000136530
fanci
Fanconi anemia, complementation group I
chr16_+_27449058 1.09 ENSDART00000132329
stx17
syntaxin 17
chr3_-_23466232 1.04 ENSDART00000156897
ube2z
ubiquitin-conjugating enzyme E2Z
chr12_+_27151693 1.03 ENSDART00000066269
arl4d
ADP-ribosylation factor-like 4D
chr7_+_53952463 1.02 ENSDART00000158518
pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr7_-_19851362 1.01 ENSDART00000052902
acap1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr14_-_33245562 1.00 ENSDART00000023540
sash3
SAM and SH3 domain containing 3
chr10_+_17414243 1.00 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr4_-_20501201 0.99 ENSDART00000132464
gsap
gamma-secretase activating protein
chr8_-_19235793 0.98 ENSDART00000036148
zgc:77486
zgc:77486
chr1_-_55072375 0.98 ENSDART00000142244
dnajb1b
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr7_+_38536733 0.97 ENSDART00000052323
harbi1
harbinger transposase derived 1
chr10_+_35208897 0.96 ENSDART00000063418
nsun5
NOP2/Sun domain family, member 5
chr3_-_29557642 0.95 ENSDART00000151679
si:ch73-233k15.2
si:ch73-233k15.2
chr15_+_43682994 0.94 ENSDART00000168589
ctsc
cathepsin C
chr12_-_92728 0.93 ENSDART00000152496
adprm
ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
chr6_-_53333532 0.93 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr23_-_29627060 0.91 ENSDART00000166554
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr17_-_8828004 0.89

chr2_-_1753013 0.89 ENSDART00000126566
slc22a23
solute carrier family 22, member 23
chr4_+_20093476 0.88 ENSDART00000066961
ppp6r2a
protein phosphatase 6, regulatory subunit 2a
KN150702v1_-_111618 0.86 ENSDART00000165431
PPP1CC
protein phosphatase 1 catalytic subunit gamma
chr6_+_30385400 0.84 ENSDART00000108943
shroom2a
shroom family member 2a
chr17_-_24860499 0.84 ENSDART00000123147
zbtb8a
zinc finger and BTB domain containing 8A
chr23_-_21011877 0.83

chr20_-_4115423 0.82 ENSDART00000064365
si:ch73-111k22.2
si:ch73-111k22.2
chr5_+_38499102 0.81 ENSDART00000166657
bmp2k
BMP2 inducible kinase
chr21_+_37985567 0.80 ENSDART00000085728
klf8
Kruppel-like factor 8
chr20_+_51385348 0.80

chr21_-_37886693 0.80 ENSDART00000177664
FO704750.1
ENSDARG00000108937

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 19.7 GO:0060876 semicircular canal formation(GO:0060876)
1.2 3.6 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.7 2.1 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.5 2.6 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5 3.5 GO:0030104 water homeostasis(GO:0030104)
0.5 2.5 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.4 2.8 GO:0034982 mitochondrial protein processing(GO:0034982)
0.3 10.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.3 1.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.3 4.7 GO:0045176 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.3 2.4 GO:0006012 galactose metabolic process(GO:0006012)
0.3 2.6 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.3 0.8 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 1.7 GO:0008585 female gonad development(GO:0008585)
0.2 6.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2 1.0 GO:0030730 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.2 1.2 GO:0006828 manganese ion transport(GO:0006828)
0.2 1.6 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.2 0.4 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.2 1.2 GO:0016559 peroxisome fission(GO:0016559)
0.2 2.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 2.3 GO:0070831 basement membrane assembly(GO:0070831)
0.2 2.8 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.2 1.5 GO:0090382 phagosome maturation(GO:0090382)
0.2 2.6 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.5 GO:0034311 diol metabolic process(GO:0034311)
0.1 3.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.6 GO:0014028 notochord formation(GO:0014028)
0.1 1.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.5 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 5.2 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.1 1.0 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.1 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.3 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535) cellular response to virus(GO:0098586)
0.1 2.7 GO:0051607 defense response to virus(GO:0051607)
0.1 2.2 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 0.6 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 1.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 4.5 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.1 2.1 GO:0030301 cholesterol transport(GO:0030301)
0.1 1.0 GO:0006465 signal peptide processing(GO:0006465)
0.1 3.1 GO:0007605 sensory perception of sound(GO:0007605)
0.1 7.9 GO:0008544 epidermis development(GO:0008544)
0.1 2.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 6.8 GO:0001894 tissue homeostasis(GO:0001894)
0.1 3.6 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 2.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 4.3 GO:0002573 myeloid leukocyte differentiation(GO:0002573)
0.1 1.4 GO:0043486 histone exchange(GO:0043486)
0.1 3.8 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 1.4 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.1 1.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0010458 exit from mitosis(GO:0010458)
0.0 1.9 GO:0042742 defense response to bacterium(GO:0042742)
0.0 1.8 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 1.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 2.6 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 4.2 GO:0006413 translational initiation(GO:0006413)
0.0 5.3 GO:0031016 pancreas development(GO:0031016)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0007032 endosome organization(GO:0007032)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.0 GO:0006869 lipid transport(GO:0006869)
0.0 7.5 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0061689 tricellular tight junction(GO:0061689)
0.8 4.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.6 3.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 27.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.4 2.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.4 5.5 GO:0043296 apical junction complex(GO:0043296)
0.4 3.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 6.4 GO:0030057 desmosome(GO:0030057)
0.3 3.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.3 2.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 2.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.0 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 3.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 4.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.4 GO:0000812 Swr1 complex(GO:0000812)
0.1 3.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.5 GO:0044545 NSL complex(GO:0044545)
0.1 3.8 GO:0030496 midbody(GO:0030496)
0.1 4.3 GO:0016592 mediator complex(GO:0016592)
0.1 1.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 5.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 5.4 GO:0005764 lysosome(GO:0005764)
0.0 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0000792 heterochromatin(GO:0000792)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 3.4 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.6 5.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.5 2.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.5 2.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.5 2.4 GO:0004335 galactokinase activity(GO:0004335)
0.4 6.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.3 2.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 8.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 1.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 1.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.3 1.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 4.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 1.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.2 1.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 6.4 GO:0008013 beta-catenin binding(GO:0008013)
0.2 0.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 2.6 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 2.5 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 3.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.1 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 4.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 3.6 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 5.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.8 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.1 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 4.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 18.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 5.1 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 17.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 13.8 GO:0008289 lipid binding(GO:0008289)
0.0 5.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.6 GO:0042393 histone binding(GO:0042393)
0.0 8.6 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.6 GO:0008168 methyltransferase activity(GO:0008168)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 6.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 1.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.4 8.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.4 2.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 6.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.4 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 4.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 3.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 4.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport