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Results for irf6

Z-value: 0.47

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Transcription factors associated with irf6

Gene Symbol Gene ID Gene Info
ENSDARG00000101986 interferon regulatory factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf6dr10_dc_chr22_+_1153361_11535270.485.7e-02Click!

Activity profile of irf6 motif

Sorted Z-values of irf6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of irf6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_54505313 1.00 ENSDART00000100619
ENSDART00000163796
zgc:158803
chr1_-_54505112 0.77 ENSDART00000100619
ENSDART00000163796
zgc:158803
chr16_+_19831573 0.64 ENSDART00000135359
metastasis associated in colon cancer 1
chr6_-_10492724 0.53 ENSDART00000002247
Sp3b transcription factor
chr18_+_44539099 0.51 ENSDART00000140672
suppression of tumorigenicity 14 (colon carcinoma) a
chr17_-_22532811 0.50 ENSDART00000079401
si:ch211-125o16.4
chr21_-_22507089 0.46 ENSDART00000177084
myosin VB
chr18_+_44538877 0.45 ENSDART00000086952
suppression of tumorigenicity 14 (colon carcinoma) a
chr15_-_25024630 0.44

chr4_-_17680826 0.42 ENSDART00000066997
DNA-damage regulated autophagy modulator 1
chr7_+_68964813 0.38 ENSDART00000166258
MARVEL domain containing 3
chr18_-_44539130 0.37

chr19_-_15516318 0.36 ENSDART00000151454
serine incorporator 2
chr6_-_10492439 0.33 ENSDART00000002247
Sp3b transcription factor
chr1_-_54504911 0.32 ENSDART00000100619
ENSDART00000163796
zgc:158803
chr11_-_30261689 0.32 ENSDART00000101667
mitogen-activated protein kinase kinase kinase kinase 3a
chr12_-_16403282 0.29 ENSDART00000037601
ribonuclease P/MRP 30 subunit
chr16_+_27449058 0.28 ENSDART00000132329
syntaxin 17
chr10_-_33435736 0.25 ENSDART00000023509
spindle and kinetochore associated complex subunit 2
chr9_+_23954669 0.18 ENSDART00000145120
ENSDARG00000040445
chr9_+_23954607 0.16 ENSDART00000145120
ENSDARG00000040445
chr9_+_23954807 0.16 ENSDART00000145120
ENSDARG00000040445
chr10_+_28273581 0.13 ENSDART00000131003
ring finger protein, transmembrane 1
chr12_-_16403608 0.05 ENSDART00000037601
ribonuclease P/MRP 30 subunit
chr16_+_10666906 0.02 ENSDART00000091241
si:ch73-22o12.1
chr11_-_30261559 0.02 ENSDART00000101667
mitogen-activated protein kinase kinase kinase kinase 3a
chr7_+_56171081 0.01 ENSDART00000073596
ENSDART00000123273
increased sodium tolerance 1 homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.4 GO:0010632 regulation of epithelial cell migration(GO:0010632)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins