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Results for irx2a

Z-value: 0.65

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Transcription factors associated with irx2a

Gene Symbol Gene ID Gene Info
ENSDARG00000001785 iroquois homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx2adr10_dc_chr16_-_543957_544033-0.107.1e-01Click!

Activity profile of irx2a motif

Sorted Z-values of irx2a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of irx2a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_18403762 0.92 ENSDART00000021559
coronin, actin binding protein, 1B
chr21_-_32027717 0.64 ENSDART00000131651
ENSDARG00000073961
chr23_+_44729874 0.61 ENSDART00000056935
trafficking protein particle complex 1
chr15_+_28242729 0.59 ENSDART00000037119
solute carrier family 46 (folate transporter), member 1
chr22_-_11049321 0.59 ENSDART00000006927
ENSDART00000170509
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr24_-_32259086 0.59 ENSDART00000048633
tRNA aspartic acid methyltransferase 1
chr16_-_42015262 0.57 ENSDART00000136742
ENSDARG00000091933
chr21_-_804453 0.53

chr1_+_39315964 0.53 ENSDART00000011727
coiled-coil domain containing 149b
chr18_+_12853364 0.53

chr1_-_17643893 0.53 ENSDART00000134561
melatonin receptor 1A a
chr8_+_25940758 0.52 ENSDART00000140626
ENSDARG00000061023
chr21_+_21302661 0.48 ENSDART00000137693
succinate dehydrogenase complex assembly factor 1
chr5_-_3323004 0.48

chr5_+_31259894 0.47 ENSDART00000036235
iron-sulfur cluster assembly enzyme b
chr6_+_48721961 0.47 ENSDART00000164142
ENSDART00000167131
si:dkeyp-6a3.1
chr22_+_10752209 0.46 ENSDART00000081183
ectodermal-neural cortex 3
chr16_-_42225498 0.44 ENSDART00000084715
alkB homolog 8, tRNA methyltransferase
chr8_+_23126151 0.43 ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr5_-_12060314 0.42 ENSDART00000133587
WD repeat and SOCS box containing 2
chr13_-_25620394 0.42 ENSDART00000111567
sphingosine-1-phosphate lyase 1
chr3_+_25719002 0.41 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr11_-_16017396 0.41 ENSDART00000081062
actin related protein 2/3 complex, subunit 4, like
chr16_+_32177564 0.41

chr23_+_44828346 0.41 ENSDART00000140799
zgc:85858
chr2_+_38959335 0.40 ENSDART00000109219
RAS (RAD and GEM)-like GTP binding 2
chr19_-_11397220 0.40 ENSDART00000104933
endonuclease/exonuclease/phosphatase family domain containing 1
chr7_-_51497945 0.40 ENSDART00000054591
bone morphogenetic protein 15
chr21_-_32003326 0.39 ENSDART00000114964
zgc:165573
chr23_+_44730111 0.39 ENSDART00000177271
trafficking protein particle complex 1
chr2_-_34154845 0.38 ENSDART00000133381
centromere protein L
chr16_+_40558786 0.38 ENSDART00000126129
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr1_+_11661380 0.38 ENSDART00000144475
clathrin, light chain A
chr9_-_22014768 0.37 ENSDART00000101986
mitochondrial ribosomal protein L30
chr24_+_31751950 0.36 ENSDART00000156493
ENSDARG00000096998
chr25_-_34621069 0.36 ENSDART00000123892
histone 1, H4, like
chr22_-_28276824 0.35 ENSDART00000147686
si:dkey-222p3.1
chr18_-_11426 0.34 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr13_-_15662476 0.34 ENSDART00000145914
ENSDART00000010286
BCL2-associated athanogene 5
chr10_-_27028132 0.33 ENSDART00000113353
ENSDARG00000075422
chr9_-_29687072 0.32 ENSDART00000060246
DnaJ (Hsp40) homolog, subfamily C, member 3a
chr2_+_54911012 0.32 ENSDART00000027313
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr18_-_14774644 0.32 ENSDART00000125979
teashirt zinc finger homeobox 3a
chr7_+_27626968 0.32 ENSDART00000178912
tubby bipartite transcription factor
chr24_-_19573615 0.32 ENSDART00000158952
ENSDART00000109107
ENSDART00000056082
cysteine-serine-rich nuclear protein 1b
chr12_-_4212010 0.30 ENSDART00000059298
zgc:92313
chr8_+_26352980 0.30 ENSDART00000053460
ENSDART00000086763
N-acetyltransferase 6
hyaluronoglucosaminidase 3
chr7_-_24373579 0.30 ENSDART00000048921
GP1 homolog, RAB6A GEF complex partner 1
chr18_-_20619155 0.28 ENSDART00000151864
BCL2-like 13 (apoptosis facilitator)
chr5_-_12060382 0.28 ENSDART00000133587
WD repeat and SOCS box containing 2
chr22_+_10752245 0.28 ENSDART00000050171
ectodermal-neural cortex 3
chr9_-_22014861 0.28 ENSDART00000101986
mitochondrial ribosomal protein L30
chr5_-_18393705 0.27 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr13_-_30011613 0.27 ENSDART00000110157
trypsin domain containing 1
chr21_-_10962154 0.27 ENSDART00000084061
neural precursor cell expressed, developmentally down-regulated 4-like
chr9_+_41223155 0.27 ENSDART00000014660
ORMDL sphingolipid biosynthesis regulator 1
chr10_-_16069787 0.26 ENSDART00000122540
aldehyde dehydrogenase 7 family, member A1
chr13_-_11838653 0.26 ENSDART00000066230
ADP ribosylation factor like GTPase 3
chr25_-_34340016 0.26 ENSDART00000039485
GABA(A) receptor-associated protein like 2
chr17_-_30504063 0.25 ENSDART00000087111
intersectin 2b
chr7_+_13329491 0.25 ENSDART00000158797
ankyrin repeat and death domain containing 1A
chr7_+_21006803 0.25 ENSDART00000052942
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr3_+_25718973 0.25 ENSDART00000007119
major facilitator superfamily domain containing 6-like
chr12_+_46944395 0.25 ENSDART00000149032
ornithine aminotransferase
chr11_+_42352106 0.24 ENSDART00000169938
interleukin 17 receptor D
chr5_+_40896478 0.24 ENSDART00000039369
Fanconi anemia, complementation group G
chr13_-_26668719 0.24 ENSDART00000139264
vaccinia related kinase 2
chr12_-_36282538 0.24 ENSDART00000165935
NPL4 homolog, ubiquitin recognition factor
chr25_-_3633631 0.23 ENSDART00000159335
ENSDART00000088077
zgc:158398
chr3_-_33362384 0.23 ENSDART00000020342
small G protein signaling modulator 3
chr18_+_284210 0.23 ENSDART00000158040
La ribonucleoprotein domain family, member 6
chr9_-_22014927 0.23 ENSDART00000101986
mitochondrial ribosomal protein L30
chr13_+_11741597 0.23

chr12_+_6032064 0.23 ENSDART00000142418
sphingomyelin synthase 1
chr17_+_43478181 0.23 ENSDART00000055487
charged multivesicular body protein 3
chr5_+_52199662 0.22

chr16_-_40558536 0.22 ENSDART00000075718
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr12_-_46943791 0.22 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr15_+_11798993 0.22 ENSDART00000163844
si:dkey-31c13.1
chr2_+_34155114 0.22 ENSDART00000137170
aspartyl-tRNA synthetase 2, mitochondrial
chr16_-_22218191 0.21 ENSDART00000140175
si:dkey-71b5.3
chr2_-_52156537 0.21 ENSDART00000168875
si:ch211-9d9.1
chr1_-_11191824 0.21 ENSDART00000163971
ENSDART00000123431
IQ motif containing E
chr13_-_30011574 0.21 ENSDART00000110157
trypsin domain containing 1
chr17_+_34238753 0.21 ENSDART00000014306
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr23_-_18454945 0.20 ENSDART00000016891
hydroxysteroid (17-beta) dehydrogenase 10
chr14_-_25688444 0.20 ENSDART00000172909
antioxidant 1 copper chaperone
chr5_-_12225160 0.20 ENSDART00000156408
leucine-zipper-like transcription regulator 1
chr19_-_27755498 0.20 ENSDART00000137346
zinc ribbon domain containing 1
chr3_-_23473646 0.19 ENSDART00000078423
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_-_7522853 0.19 ENSDART00000168194
GA binding protein transcription factor, beta subunit 2a
chr7_-_28376722 0.19 ENSDART00000150148
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr25_-_34642724 0.19 ENSDART00000121963
histone 1, H4, like
chr18_-_20618924 0.18 ENSDART00000090156
ENSDART00000151980
BCL2-like 13 (apoptosis facilitator)
chr19_+_5562075 0.18 ENSDART00000148794
junction plakoglobin b
chr12_-_4212149 0.18 ENSDART00000059298
zgc:92313
chr7_+_23881828 0.18 ENSDART00000076735
low density lipoprotein receptor-related protein 10
chr6_-_10676890 0.18 ENSDART00000036456
cytochrome c, somatic b
chr13_+_45445475 0.18

chr17_-_9839620 0.18 ENSDART00000148463
sorting nexin 6
chr10_-_321050 0.18 ENSDART00000165244
ENSDART00000161493
v-akt murine thymoma viral oncogene homolog 2, like
chr13_-_49826526 0.17 ENSDART00000099475
nidogen 1a
chr10_+_36094175 0.17 ENSDART00000164678
katanin p60 subunit A-like 1
chr8_+_47565879 0.17

chr2_+_31823672 0.17 ENSDART00000086608
RAN binding protein 9
chr16_-_22218557 0.17 ENSDART00000140175
si:dkey-71b5.3
KN150226v1_+_11579 0.16

chr3_-_35734943 0.16 ENSDART00000135957
SUZ12 polycomb repressive complex 2a subunit
chr24_-_31967674 0.16 ENSDART00000156060
si:ch73-78o10.1
chr1_-_17643855 0.16 ENSDART00000134561
melatonin receptor 1A a
chr14_-_49777408 0.16 ENSDART00000166463
CCR4-NOT transcription complex, subunit 6b
chr4_-_16779846 0.15

chr23_-_27515964 0.15 ENSDART00000167838
disco-interacting protein 2 homolog Ba
chr18_-_13153190 0.15 ENSDART00000092648
transmembrane protein 5
chr18_-_42072998 0.15

chr10_+_24530670 0.15

chr7_+_24373948 0.15 ENSDART00000150233
glucosidase, beta (bile acid) 2
chr5_+_40896320 0.15 ENSDART00000039369
Fanconi anemia, complementation group G
chr2_-_11720585 0.14 ENSDART00000019392
short chain dehydrogenase/reductase family 16C, member 5a
chr15_-_21003820 0.14 ENSDART00000152371
ubiquitin specific peptidase 2a
chr7_+_21651458 0.14 ENSDART00000088041
UFM1-specific peptidase 1 (non-functional)
chr3_+_57927416 0.14 ENSDART00000170144
pyrroline-5-carboxylate reductase 1a
chr13_-_15662599 0.14 ENSDART00000145914
ENSDART00000010286
BCL2-associated athanogene 5
chr15_+_8791540 0.14 ENSDART00000033871
adaptor-related protein complex 2, sigma 1 subunit
chr17_+_17745119 0.14 ENSDART00000138189
ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr23_+_5632124 0.14 ENSDART00000059307
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr8_-_25547089 0.14 ENSDART00000078022
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr20_+_31314629 0.14 ENSDART00000020252
protein disulfide isomerase family A, member 6
chr16_+_30646457 0.13 ENSDART00000058785
family with sequence similarity 210, member Ab
chr3_-_43120399 0.13 ENSDART00000166021
stannin
chr24_+_2962301 0.13 ENSDART00000170835
enoyl-CoA delta isomerase 2
chr18_-_42072902 0.13

chr21_+_698978 0.13 ENSDART00000171800
ENSDART00000160956
ornithine decarboxylase antizyme 1b
chr12_+_13704914 0.13 ENSDART00000152257
protein phosphatase 1, regulatory subunit 16A
chr6_+_14854101 0.12 ENSDART00000087782
mitochondrial ribosomal protein S9
chr7_-_69576270 0.12

chr19_+_35155362 0.12 ENSDART00000146777
ENSDART00000103276
family with sequence similarity 206, member A
chr1_-_11191863 0.12 ENSDART00000163971
ENSDART00000123431
IQ motif containing E
chr21_+_3645203 0.12 ENSDART00000099535
SPOUT domain containing methyltransferase 1
chr15_+_28242899 0.12 ENSDART00000037119
solute carrier family 46 (folate transporter), member 1
chr20_-_33887129 0.12 ENSDART00000020183
family with sequence similarity 102, member B, b
chr2_+_47619337 0.11 ENSDART00000141974
acyl-CoA synthetase long-chain family member 3b
KN149895v1_+_73008 0.11

chr4_-_28364228 0.11 ENSDART00000064219
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr3_+_17801981 0.10 ENSDART00000164663
ATP citrate lyase a
chr7_-_73632999 0.10 ENSDART00000122392
histone cluster 2 H2A family member b
chr22_-_11618612 0.10 ENSDART00000109596
dipeptidyl-peptidase 4
chr12_-_4212095 0.10 ENSDART00000059298
zgc:92313
chr13_+_32505709 0.09 ENSDART00000141057
si:ch211-206k20.5
chr23_+_34037058 0.09 ENSDART00000140666
pyridoxal phosphate binding protein
chr19_-_42933592 0.09 ENSDART00000007642
zgc:110239
chr9_+_8418549 0.09 ENSDART00000043067
zgc:171776
chr13_-_44601523 0.09 ENSDART00000074761
zinc finger, AN1-type domain 3
chr2_+_31823750 0.09 ENSDART00000086608
RAN binding protein 9
chr21_-_37750338 0.09 ENSDART00000133585
family with sequence similarity 114, member A2
chr14_-_28261949 0.09 ENSDART00000126095
preproinsulin b
KN150226v1_+_11474 0.08

chr6_-_10728644 0.08 ENSDART00000151102
notum pectinacetylesterase 2
chr3_-_35735085 0.08 ENSDART00000135957
SUZ12 polycomb repressive complex 2a subunit
chr19_+_7630847 0.08 ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr24_+_14569372 0.07 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr14_+_31681774 0.07 ENSDART00000105760
zic family member 6
chr1_-_44239584 0.07 ENSDART00000137216
transmembrane protein 176
chr1_+_14539897 0.07 ENSDART00000109911
heparan-alpha-glucosaminide N-acetyltransferase
chr12_-_48391342 0.06 ENSDART00000153209
DnaJ (Hsp40) homolog, subfamily B, member 12b
chr8_-_30781902 0.06 ENSDART00000147332
glutathione S-transferase theta 1a
chr13_+_33237979 0.06 ENSDART00000158709
BRF1, RNA polymerase III transcription initiation factor a
chr18_-_38289553 0.06 ENSDART00000098889
cell cycle associated protein 1b
chr22_+_1750530 0.06

chr13_-_24695520 0.06 ENSDART00000142745
STE20-like kinase a
chr5_-_43219303 0.06 ENSDART00000022481
methylcrotonoyl-CoA carboxylase 2 (beta)
chr7_+_71585147 0.05 ENSDART00000161344
NOL1/NOP2/Sun domain family, member 6
chr6_+_43452686 0.05 ENSDART00000075521
zgc:113054
chr22_+_12570345 0.05 ENSDART00000140054
ENSDARG00000041602
chr11_+_38013564 0.05 ENSDART00000171496
cyclin dependent kinase 18
chr25_+_9904821 0.05

chr20_-_20370397 0.05 ENSDART00000009356
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr25_+_3634121 0.05 ENSDART00000153905
THO complex 5
chr2_+_31823314 0.05 ENSDART00000086608
RAN binding protein 9
chr6_-_10728582 0.05 ENSDART00000151102
notum pectinacetylesterase 2
chr25_-_22954929 0.04 ENSDART00000024633
dual specificity phosphatase 8a
chr5_+_41463969 0.04 ENSDART00000035235
si:ch211-202a12.4
chr8_-_21071055 0.04 ENSDART00000131322
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr11_+_17040226 0.04

chr2_+_34154885 0.04 ENSDART00000137170
aspartyl-tRNA synthetase 2, mitochondrial
chr13_-_32505425 0.04 ENSDART00000148040
matrilin 3b
chr17_-_43437795 0.04 ENSDART00000043866
polo-like kinase 4 (Drosophila)
chr1_+_35919158 0.04 ENSDART00000176692
ENSDARG00000108193
chr15_-_24243608 0.03 ENSDART00000077980
pipecolic acid oxidase
chr19_-_20862383 0.03 ENSDART00000111409
ENSDART00000140711
TBC1 domain family, member 5
chr8_+_44933065 0.03 ENSDART00000098567
ENSDARG00000016545
chr5_-_66502280 0.03 ENSDART00000065264
cell division cycle associated 5
chr5_+_63716392 0.03 ENSDART00000015940
endothelial differentiation-related factor 1
chr7_+_57374714 0.03 ENSDART00000110623
arylsulfatase family, member J
chr8_+_44933013 0.03 ENSDART00000098567
ENSDARG00000016545
chr8_-_21071108 0.03 ENSDART00000137838
aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1
chr21_-_43915591 0.03

chr25_-_20835675 0.02

chr25_-_31952245 0.02 ENSDART00000153892
centrosomal protein 152
chr23_+_24999817 0.02 ENSDART00000137486
kelch-like family member 21

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0090083 inclusion body assembly(GO:0070841) regulation of inclusion body assembly(GO:0090083)
0.1 0.5 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.3 GO:0090277 positive regulation of peptide secretion(GO:0002793) positive regulation of insulin secretion(GO:0032024) positive regulation of hormone secretion(GO:0046887) positive regulation of peptide hormone secretion(GO:0090277)
0.1 0.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.3 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.5 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.2 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.1 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.4 GO:0043901 negative regulation of multi-organism process(GO:0043901)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.4 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.2 GO:1901985 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.3 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 1.0 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.3 GO:0034066 RIC1-RGP1 guanyl-nucleotide exchange factor complex(GO:0034066)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1905202 methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005542 folic acid binding(GO:0005542)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.4 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.1 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity(GO:0043878) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism