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Results for irx5a+irx5b_irx3b

Z-value: 2.75

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Transcription factors associated with irx5a+irx5b_irx3b

Gene Symbol Gene ID Gene Info
irx5a
ENSDARG00000034043 iroquois homeobox 5a
irx5b
ENSDARG00000074070 iroquois homeobox 5b
irx3b
ENSDARG00000031138 iroquois homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx5adr10_dc_chr7_-_35438739_35438853-0.902.0e-06Click!
irx5bdr10_dc_chr25_+_35602451_35602500-0.887.2e-06Click!
irx3bdr10_dc_chr25_+_35901081_35901148-0.861.6e-05Click!

Activity profile of irx5a+irx5b_irx3b motif

Sorted Z-values of irx5a+irx5b_irx3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of irx5a+irx5b_irx3b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_33264349 8.64

chr21_+_11943637 7.68 ENSDART00000141306
zgc:162344
zgc:162344
chr17_+_24791024 7.02 ENSDART00000130871
spdya
speedy/RINGO cell cycle regulator family member A
chr23_+_46000362 6.61 ENSDART00000023944
lmnl3
lamin L3
chr2_+_216779 6.44 ENSDART00000101071
zgc:113293
zgc:113293
chr6_+_51713264 6.38 ENSDART00000146281
fam65c
family with sequence similarity 65, member C
chr17_+_24790812 6.25 ENSDART00000082251
spdya
speedy/RINGO cell cycle regulator family member A
chr2_+_216931 5.83 ENSDART00000101071
zgc:113293
zgc:113293
chr16_-_47446494 5.58 ENSDART00000032188
si:dkey-256h2.1
si:dkey-256h2.1
chr19_+_32670271 5.33

chr5_+_3567992 5.22 ENSDART00000129329
rpain
RPA interacting protein
chr8_-_20882626 5.09 ENSDART00000025356
haus5
HAUS augmin-like complex, subunit 5
chr21_+_26954898 4.85 ENSDART00000114469
fkbp2
FK506 binding protein 2
chr16_-_21734502 4.83 ENSDART00000179125
CABZ01009710.1
ENSDARG00000106589
chr9_+_22166405 4.76 ENSDART00000135032
si:dkey-57a22.11
si:dkey-57a22.11
chr12_+_17032829 4.67 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr2_+_55869860 4.52

chr22_+_10752209 4.49 ENSDART00000081183
enc3
ectodermal-neural cortex 3
chr12_+_17032997 4.45 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr12_+_47448318 4.23 ENSDART00000152857
fmn2b
formin 2b
chr12_+_13053552 4.18 ENSDART00000124799
si:ch211-103b1.2
si:ch211-103b1.2
chr7_+_38444768 4.05 ENSDART00000024590
syt13
synaptotagmin XIII
chr6_+_40924559 3.95 ENSDART00000133599
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_-_65564733 3.93 ENSDART00000178162
CABZ01049025.1
ENSDARG00000107190
chr4_-_6407602 3.83 ENSDART00000134376
CR356233.2
ENSDARG00000093020
chr3_+_17901295 3.79 ENSDART00000035531
mettl26
methyltransferase like 26
chr12_+_22552867 3.76 ENSDART00000152930
cdca9
cell division cycle associated 9
chr2_+_56534374 3.72 ENSDART00000113964
POLR2E (1 of many)
RNA polymerase II subunit E
chr3_+_33308831 3.69 ENSDART00000164322
gtpbp1
GTP binding protein 1
chr6_+_33092094 3.65 ENSDART00000122242
pomgnt1
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr21_-_32747592 3.64

chr23_+_370986 3.60 ENSDART00000055148
zgc:101663
zgc:101663
chr16_-_42236126 3.56 ENSDART00000076030
fbl
fibrillarin
chr6_+_40469996 3.53 ENSDART00000103868
zgc:152986
zgc:152986
chr1_-_33717934 3.52 ENSDART00000083736
lmo7b
LIM domain 7b
chr24_+_12689711 3.52 ENSDART00000114762
nanog
nanog homeobox
chr24_+_9898743 3.51 ENSDART00000144186
pou6f2
POU class 6 homeobox 2
chr14_+_7391258 3.44 ENSDART00000162363
brd8
bromodomain containing 8
chr10_+_8670611 3.40 ENSDART00000129643
aplnrb
apelin receptor b
chr21_+_11943609 3.37 ENSDART00000155426
ENSDART00000102463
zgc:162344
zgc:162344
chr19_-_7124381 3.37 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
KN150034v1_+_1223 3.35

chr10_+_37457234 3.32 ENSDART00000136554
akap1a
A kinase (PRKA) anchor protein 1a
chr18_+_26061521 3.25 ENSDART00000015712
znf710a
zinc finger protein 710a
chr10_+_24530670 3.24

chr5_-_65750231 3.15 ENSDART00000160189
hip1rb
huntingtin interacting protein 1 related b
chr8_-_4704361 3.15 ENSDART00000064201
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr20_+_31036284 3.07 ENSDART00000153344
sod2
superoxide dismutase 2, mitochondrial
chr23_-_31528548 3.06

chr4_-_13932592 3.02 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr4_-_7861030 3.01 ENSDART00000067339
mcm10
minichromosome maintenance 10 replication initiation factor
chr9_+_21548183 3.00 ENSDART00000059402
n6amt2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr13_+_22586873 2.98 ENSDART00000134122
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_+_34692221 2.92 ENSDART00000085087
ddx28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr20_-_27291090 2.91 ENSDART00000020710
ENSDART00000149024
btbd7
BTB (POZ) domain containing 7
chr24_-_24837798 2.91 ENSDART00000144961
slc51a
solute carrier family 51, alpha subunit
chr8_+_37716781 2.90 ENSDART00000108556
npm2a
nucleophosmin/nucleoplasmin, 2a
chr12_+_17032963 2.90 ENSDART00000028003
ankrd22
ankyrin repeat domain 22
chr14_+_1226767 2.88 ENSDART00000127477
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr22_+_1418852 2.87

chr3_-_86374 2.86 ENSDART00000138302
zgc:110249
zgc:110249
chr10_+_32107014 2.86 ENSDART00000137373
si:ch211-266i6.3
si:ch211-266i6.3
chr2_+_15432208 2.85 ENSDART00000027171
f3b
coagulation factor IIIb
chr8_+_25072241 2.80 ENSDART00000143922
atxn7l2b
ataxin 7-like 2b
chr5_+_65491173 2.75 ENSDART00000050847
ENSDART00000172117
GLDC
glycine decarboxylase
chr6_+_30123156 2.72 ENSDART00000022586
lrrc40
leucine rich repeat containing 40
chr5_+_33978279 2.72 ENSDART00000016314
gfm2
G elongation factor, mitochondrial 2
chr19_+_7254917 2.72 ENSDART00000123934
hsd17b8
hydroxysteroid (17-beta) dehydrogenase 8
chr6_-_14841372 2.72 ENSDART00000167436
CU929521.1
ENSDARG00000097482
chr5_+_65491288 2.71 ENSDART00000050847
ENSDART00000172117
GLDC
glycine decarboxylase
chr6_+_49902765 2.69 ENSDART00000023515
chmp4ba
charged multivesicular body protein 4Ba
chr16_-_21734465 2.69

chr11_-_22450582 2.69

chr22_+_35156074 2.68 ENSDART00000130581
rnf13
ring finger protein 13
chr15_+_28242899 2.67 ENSDART00000037119
slc46a1
solute carrier family 46 (folate transporter), member 1
chr3_+_28519110 2.66 ENSDART00000151116
ENSDART00000153977
CR792438.2
ENSDARG00000096409
chr5_-_58326476 2.64 ENSDART00000033923
mis12
MIS12 kinetochore complex component
chr20_-_27291231 2.64 ENSDART00000020710
ENSDART00000149024
btbd7
BTB (POZ) domain containing 7
chr10_+_37457062 2.63 ENSDART00000136554
akap1a
A kinase (PRKA) anchor protein 1a
chr23_-_20050419 2.61 ENSDART00000054659
fam58a
family with sequence similarity 58, member A
chr18_-_31126989 2.61 ENSDART00000039495
pdcd5
programmed cell death 5
chr10_-_22942557 2.60 ENSDART00000131992
si:ch1073-143l10.2
si:ch1073-143l10.2
chr24_+_32610430 2.58 ENSDART00000132417
yme1l1a
YME1-like 1a
chr22_-_510040 2.56 ENSDART00000140101
ccnd3
cyclin D3
chr25_+_7261050 2.55 ENSDART00000163017
prc1a
protein regulator of cytokinesis 1a
chr12_-_42212994 2.54 ENSDART00000171075
zgc:111868
zgc:111868
chr2_+_15432130 2.53 ENSDART00000027171
f3b
coagulation factor IIIb
chr8_+_3373066 2.53 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr11_-_6979695 2.52 ENSDART00000173242
ENSDART00000172896
ENSDART00000102493
zgc:173548
zgc:173548
KN150266v1_-_68652 2.52

chr20_-_22899048 2.51 ENSDART00000063609
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr1_+_50547385 2.50 ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr3_-_26060098 2.50 ENSDART00000136001
ypel3
yippee-like 3
chr16_-_21734257 2.48

chr15_+_28242729 2.47 ENSDART00000037119
slc46a1
solute carrier family 46 (folate transporter), member 1
chr9_-_19358774 2.44 ENSDART00000099396
zgc:152951
zgc:152951
chr8_-_53165501 2.44 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr20_+_25812737 2.44 ENSDART00000033436
cep135
centrosomal protein 135
chr7_-_6334676 2.44 ENSDART00000081359
zgc:110425
zgc:110425
chr3_-_26060047 2.42 ENSDART00000136001
ypel3
yippee-like 3
chr5_-_27953681 2.39 ENSDART00000078708
zgc:162952
zgc:162952
chr23_-_33753484 2.35 ENSDART00000138416
tfcp2
transcription factor CP2
chr15_+_19388905 2.34 ENSDART00000149926
vps26b
VPS26 retromer complex component B
chr10_-_41380870 2.34 ENSDART00000160174
brf2
BRF2, RNA polymerase III transcription initiation factor
chr10_+_45108698 2.32

chr19_-_28247275 2.32

chr3_+_42395984 2.32 ENSDART00000162096
micall2a
mical-like 2a
chr12_-_36046366 2.31

chr18_-_958923 2.28

chr18_+_24490621 2.28 ENSDART00000143108
CR847971.1
ENSDARG00000091941
chr18_-_44854242 2.27 ENSDART00000086823
srpr
signal recognition particle receptor (docking protein)
chr20_+_41351373 2.25 ENSDART00000153067
BX510919.1
ENSDARG00000096764
KN150034v1_+_1158 2.25

chr23_-_36207066 2.25 ENSDART00000147598
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr14_-_30604897 2.24 ENSDART00000161540
si:zfos-80g12.1
si:zfos-80g12.1
chr5_-_23211957 2.23 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr23_-_36547458 2.22 ENSDART00000006881
zbtb39
zinc finger and BTB domain containing 39
chr22_-_6532901 2.22 ENSDART00000106100
zgc:171490
zgc:171490
chr17_+_22291644 2.22 ENSDART00000151929
ENSDART00000089919
ENSDART00000000804
slc8a1b
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr8_+_52458939 2.22

chr19_-_25565317 2.21 ENSDART00000175266
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr2_-_40857927 2.21 ENSDART00000157099
CT583650.1
ENSDARG00000096869
chr7_+_26378093 2.19 ENSDART00000173823
ENSDART00000101053
tp53i11a
tumor protein p53 inducible protein 11a
chr9_+_21548044 2.19 ENSDART00000147619
n6amt2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr17_+_15780112 2.19 ENSDART00000027667
ENSDART00000161637
rragd
ras-related GTP binding D
chr3_+_17901095 2.17 ENSDART00000035531
mettl26
methyltransferase like 26
chr22_-_5600910 2.17 ENSDART00000179579
CABZ01075081.1
ENSDARG00000106226
chr1_+_9443056 2.16 ENSDART00000110698
rbm46
RNA binding motif protein 46
chr6_-_54049582 2.15

chr18_+_1018614 2.15 ENSDART00000161206
pkma
pyruvate kinase, muscle, a
chr22_+_2483845 2.13 ENSDART00000170192
CU570894.1
ENSDARG00000103886
chr9_-_19358693 2.13 ENSDART00000099396
zgc:152951
zgc:152951
chr3_+_17900981 2.12 ENSDART00000035531
mettl26
methyltransferase like 26
chr14_-_32755454 2.12 ENSDART00000074720
dlg3
discs, large homolog 3 (Drosophila)
chr11_-_1061904 2.12 ENSDART00000173253
ENSDART00000172765
CU914760.1
ENSDARG00000105313
chr4_+_5147577 2.12 ENSDART00000067392
tigarb
tp53-induced glycolysis and apoptosis regulator b
chr16_+_25269188 2.12 ENSDART00000147584
hcst
hematopoietic cell signal transducer
chr16_+_25201900 2.11 ENSDART00000163244
si:ch211-261d7.6
si:ch211-261d7.6
chr8_-_28359022 2.11 ENSDART00000062693
ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr5_+_68960543 2.10 ENSDART00000169013
arl6ip4
ADP-ribosylation factor-like 6 interacting protein 4
chr5_+_33978304 2.10 ENSDART00000016314
gfm2
G elongation factor, mitochondrial 2
chr13_-_24614722 2.06 ENSDART00000031564
sfr1
SWI5-dependent homologous recombination repair protein 1
chr25_-_19388381 2.05 ENSDART00000154986
zgc:193812
zgc:193812
chr20_-_32246045 2.04 ENSDART00000048537
ENSDART00000152984
cep57l1
centrosomal protein 57, like 1
chr22_-_22315679 2.04 ENSDART00000033479
si:ch211-129c21.1
si:ch211-129c21.1
chr12_+_29017351 2.03

chr17_+_15780156 2.03 ENSDART00000027667
ENSDART00000161637
rragd
ras-related GTP binding D
chr13_+_36459562 2.02 ENSDART00000030211
gmfb
glia maturation factor, beta
chr21_+_347169 2.02 ENSDART00000168983
TMEM38B
transmembrane protein 38B
chr7_+_69888002 2.02 ENSDART00000065234
gba3
glucosidase, beta, acid 3 (gene/pseudogene)
chr10_+_33790718 2.02 ENSDART00000161430
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr5_-_7591547 2.00 ENSDART00000158447
nipbla
nipped-B homolog a (Drosophila)
chr8_-_31044580 2.00 ENSDART00000109885
snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr8_+_3372903 2.00 ENSDART00000017850
ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr17_+_24666346 2.00 ENSDART00000146309
znf593
zinc finger protein 593
chr10_-_10393735 1.99

chr11_-_37613237 1.99 ENSDART00000102868
etnk2
ethanolamine kinase 2
chr5_-_68765567 1.98 ENSDART00000097251
ENSDARG00000067564
ENSDARG00000067564
chr23_-_31719203 1.97 ENSDART00000148122
sgk1
serum/glucocorticoid regulated kinase 1
chr17_+_14956899 1.97

chr24_+_15995931 1.96 ENSDART00000105955
TIMM21
translocase of inner mitochondrial membrane 21
chr15_+_17164535 1.96 ENSDART00000155350
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr17_+_47012113 1.95

chr3_+_43073321 1.94 ENSDART00000157964
zc3h7a
zinc finger CCCH-type containing 7A
chr5_-_48028931 1.94 ENSDART00000031194
lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr17_+_24919311 1.92

chr24_+_12689887 1.91 ENSDART00000114762
nanog
nanog homeobox
chr20_-_25745974 1.90 ENSDART00000063137
ENSDART00000082099
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr1_-_20511660 1.90 ENSDART00000087670
si:dkey-253i9.4
si:dkey-253i9.4
chr17_-_29254409 1.89 ENSDART00000104219
rcor1
REST corepressor 1
chr21_-_32027717 1.89 ENSDART00000131651
ENSDARG00000073961
ENSDARG00000073961
chr14_-_32755189 1.88 ENSDART00000074720
dlg3
discs, large homolog 3 (Drosophila)
chr6_-_40924459 1.87 ENSDART00000076097
sfi1
SFI1 centrin binding protein
chr21_-_23009910 1.87 ENSDART00000016167
zw10
zw10 kinetochore protein
chr6_+_21887963 1.86 ENSDART00000157796
cbx8b
chromobox homolog 8b
chr9_-_30174641 1.85 ENSDART00000134157
ENSDART00000089206
il1rapl1a
interleukin 1 receptor accessory protein-like 1a
chr2_-_47612319 1.84 ENSDART00000133615
BX085193.1
ENSDARG00000091979
chr13_-_37504883 1.84 ENSDART00000108855
si:dkey-188i13.7
si:dkey-188i13.7
chr20_-_38031246 1.84 ENSDART00000152989
angel2
angel homolog 2 (Drosophila)
chr5_+_17276357 1.84 ENSDART00000115227
chfr
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr24_-_41275160 1.84

chr14_-_47125993 1.83 ENSDART00000124925
si:ch211-235e9.8
si:ch211-235e9.8
chr7_-_18624798 1.83 ENSDART00000113593
mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_+_10373338 1.82 ENSDART00000091377
mrs2
MRS2 magnesium transporter
chr4_+_10605257 1.81 ENSDART00000122636
ENSDART00000037140
ing3
inhibitor of growth family, member 3
chr3_+_53758069 1.79 ENSDART00000154542
olfm2a
olfactomedin 2a
chr8_-_4194010 1.79

chr20_-_32502517 1.78 ENSDART00000153411
afg1lb
AFG1 like ATPase b
chr7_+_34923319 1.78

chr16_-_21241981 1.78 ENSDART00000131582
cbx3b
chromobox homolog 3b
chr18_-_49291686 1.77 ENSDART00000174038
si:zfos-464b6.2
si:zfos-464b6.2
chr20_+_14893184 1.76 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr25_+_35742745 1.76 ENSDART00000152649
bmb
brambleberry
chr9_-_705001 1.76 ENSDART00000147092
cflarb
CASP8 and FADD-like apoptosis regulator b
chr14_-_8634381 1.76 ENSDART00000129030
zgc:153681
zgc:153681
chr20_-_25745931 1.75 ENSDART00000063137
ENSDART00000082099
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr23_-_37553481 1.75

chr13_+_36459625 1.75 ENSDART00000030211
gmfb
glia maturation factor, beta
chr9_-_4640050 1.75 ENSDART00000171634
galnt13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr10_-_22942639 1.74 ENSDART00000131992
si:ch1073-143l10.2
si:ch1073-143l10.2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.4 GO:0043622 cortical microtubule organization(GO:0043622)
1.2 3.7 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
1.2 3.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
1.1 3.4 GO:0071846 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) actin filament debranching(GO:0071846)
1.0 4.8 GO:0032790 ribosome disassembly(GO:0032790)
1.0 4.8 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 2.7 GO:2000191 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.8 3.3 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.8 3.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.8 5.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.7 4.3 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.7 3.4 GO:0010524 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of calcium ion transport into cytosol(GO:0010524) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904323) positive regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904325)
0.7 2.0 GO:0030814 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.6 3.1 GO:0001780 neutrophil homeostasis(GO:0001780)
0.6 3.7 GO:0016266 O-glycan processing(GO:0016266)
0.6 1.8 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.6 2.9 GO:0097009 energy homeostasis(GO:0097009)
0.6 3.4 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.6 2.2 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.5 6.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.5 3.2 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.5 1.6 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.5 2.1 GO:1900543 negative regulation of nucleotide metabolic process(GO:0045980) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.5 2.6 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.5 2.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.5 1.4 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.5 1.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.5 2.8 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.4 1.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.4 1.7 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.4 1.6 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 3.9 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4 1.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 5.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.4 1.1 GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway(GO:0045813)
0.4 2.9 GO:0006382 adenosine to inosine editing(GO:0006382)
0.3 1.0 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.3 1.0 GO:0042126 nitrate metabolic process(GO:0042126) nitrate assimilation(GO:0042128)
0.3 1.0 GO:0061511 centriole elongation(GO:0061511)
0.3 0.9 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.3 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 1.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.9 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.3 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 1.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 2.5 GO:0051256 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.3 2.2 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.3 1.1 GO:0071047 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.3 2.5 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.3 3.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.3 5.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.3 1.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.3 1.9 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.3 2.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.3 0.8 GO:0097037 heme export(GO:0097037)
0.3 1.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.2 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 2.7 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 1.7 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 2.9 GO:0015693 magnesium ion transport(GO:0015693)
0.2 5.2 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.2 0.7 GO:0001955 blood vessel maturation(GO:0001955)
0.2 2.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 1.9 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.2 3.0 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.2 1.4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 2.2 GO:0030259 lipid glycosylation(GO:0030259)
0.2 0.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 1.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.2 3.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 0.6 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.2 0.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 1.0 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.2 2.7 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.2 4.6 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.2 1.8 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 1.7 GO:0051382 kinetochore assembly(GO:0051382)
0.2 0.8 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 0.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 4.6 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.2 0.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 2.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.5 GO:0051026 chiasma assembly(GO:0051026) meiotic metaphase plate congression(GO:0051311)
0.2 1.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.2 0.5 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.2 1.4 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 4.0 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.2 3.8 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.2 0.5 GO:0000480 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.7 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.2 0.5 GO:0007624 ultradian rhythm(GO:0007624)
0.2 1.5 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.6 GO:0044209 AMP salvage(GO:0044209)
0.1 1.9 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of hormone metabolic process(GO:0032350) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.7 GO:0045719 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.4 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.6 GO:0048478 replication fork protection(GO:0048478)
0.1 0.8 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.0 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 1.5 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:0050892 intestinal absorption(GO:0050892)
0.1 5.4 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 1.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 0.6 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012) ventricular cardiac muscle cell development(GO:0055015)
0.1 3.2 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.4 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 1.7 GO:0006308 DNA catabolic process(GO:0006308)
0.1 2.0 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 0.6 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.3 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 3.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 1.3 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.1 0.8 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 1.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.5 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.1 1.6 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 1.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.9 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 5.0 GO:0051225 spindle assembly(GO:0051225)
0.1 1.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.8 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 0.4 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 4.7 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 3.7 GO:0006414 translational elongation(GO:0006414)
0.1 1.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.6 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.7 GO:0042026 protein refolding(GO:0042026)
0.1 0.9 GO:0010043 response to zinc ion(GO:0010043)
0.1 3.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 2.4 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) energy reserve metabolic process(GO:0006112) glucan metabolic process(GO:0044042)
0.1 2.1 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.8 GO:0003341 cilium movement(GO:0003341)
0.1 0.9 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 1.8 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 3.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0071267 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 2.7 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 2.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 5.0 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 1.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0003139 secondary heart field specification(GO:0003139)
0.0 3.5 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 3.7 GO:0006413 translational initiation(GO:0006413)
0.0 2.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 7.8 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.7 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.2 GO:0061138 morphogenesis of a branching epithelium(GO:0061138)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0046660 female sex differentiation(GO:0046660)
0.0 1.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 2.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.4 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.2 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.0 1.3 GO:0045010 actin nucleation(GO:0045010)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 2.1 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.3 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 1.2 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
0.0 1.7 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.1 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.2 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.6 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.5 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.3 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.4 GO:0009408 response to heat(GO:0009408)
0.0 0.4 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.9 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.2 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 0.5 GO:0000154 rRNA modification(GO:0000154)
0.0 0.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.5 GO:0002144 cytosolic tRNA wobble base thiouridylase complex(GO:0002144)
1.0 3.0 GO:0031298 replication fork protection complex(GO:0031298)
1.0 2.9 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.9 2.6 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.9 1.7 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.7 4.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.6 4.2 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6 3.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.5 1.6 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.4 3.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.4 3.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 1.9 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.4 3.7 GO:0070652 HAUS complex(GO:0070652)
0.3 1.0 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.3 1.0 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 1.6 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.3 4.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 1.3 GO:1902636 kinociliary basal body(GO:1902636)
0.3 0.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 2.2 GO:0061700 GATOR2 complex(GO:0061700)
0.2 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 2.7 GO:0000815 ESCRT III complex(GO:0000815)
0.2 2.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 6.0 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2 2.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 0.9 GO:0031931 TORC1 complex(GO:0031931)
0.2 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.2 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 3.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 1.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 2.1 GO:0030904 retromer complex(GO:0030904)
0.1 5.9 GO:0016605 PML body(GO:0016605)
0.1 1.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 1.0 GO:0032021 NELF complex(GO:0032021)
0.1 3.0 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 4.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 1.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 2.6 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 5.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.2 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 3.9 GO:0000776 kinetochore(GO:0000776)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.1 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 1.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.2 GO:0097433 dense body(GO:0097433)
0.1 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 7.4 GO:0030424 axon(GO:0030424)
0.0 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 3.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 7.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 4.3 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 1.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 1.2 GO:0010008 endosome membrane(GO:0010008)
0.0 3.9 GO:0019866 organelle inner membrane(GO:0019866)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.3 GO:0005794 Golgi apparatus(GO:0005794)
0.0 3.4 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0005542 folic acid binding(GO:0005542)
1.4 5.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
1.2 3.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.9 2.8 GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity(GO:0008425) quinone cofactor methyltransferase activity(GO:0030580)
0.7 2.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.6 1.9 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.6 3.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.6 3.4 GO:0060182 apelin receptor activity(GO:0060182)
0.6 1.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.6 2.2 GO:0005460 UDP-glucose transmembrane transporter activity(GO:0005460)
0.5 6.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 2.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.5 1.5 GO:0035755 cardiolipin hydrolase activity(GO:0035755)
0.5 1.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.5 2.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.5 2.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.5 2.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.4 4.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 1.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4 3.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 2.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.3 1.0 GO:0002094 polyprenyltransferase activity(GO:0002094) dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.3 1.4 GO:0072572 poly-ADP-D-ribose binding(GO:0072572)
0.3 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.3 1.0 GO:0046857 nitrite reductase [NAD(P)H] activity(GO:0008942) oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor(GO:0046857)
0.3 2.3 GO:0043295 glutathione binding(GO:0043295)
0.3 3.9 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 3.5 GO:0051018 protein kinase A binding(GO:0051018)
0.3 1.2 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 0.9 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.3 1.7 GO:0051920 peroxiredoxin activity(GO:0051920)
0.3 2.2 GO:0070728 leucine binding(GO:0070728)
0.3 1.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.3 2.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.3 6.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 4.2 GO:0048038 quinone binding(GO:0048038)
0.2 0.7 GO:0016843 amine-lyase activity(GO:0016843) strictosidine synthase activity(GO:0016844)
0.2 1.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.2 1.7 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 5.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 0.7 GO:0008251 tRNA-specific adenosine deaminase activity(GO:0008251)
0.2 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.6 GO:0071253 connexin binding(GO:0071253)
0.2 1.5 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.2 1.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 3.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 1.9 GO:0032977 membrane insertase activity(GO:0032977)
0.2 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 2.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.6 GO:0002054 nucleobase binding(GO:0002054)
0.2 0.8 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 0.6 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.2 0.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.6 GO:0004353 glutamate dehydrogenase (NAD+) activity(GO:0004352) glutamate dehydrogenase [NAD(P)+] activity(GO:0004353) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 7.0 GO:0000049 tRNA binding(GO:0000049)
0.2 0.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 0.7 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 0.8 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.2 3.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 2.7 GO:0001671 ATPase activator activity(GO:0001671)
0.2 1.4 GO:0008242 omega peptidase activity(GO:0008242)
0.2 2.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 1.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 4.9 GO:0035064 methylated histone binding(GO:0035064)
0.1 3.6 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 2.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 3.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 0.8 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 1.0 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 1.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 4.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.1 GO:0030332 cyclin binding(GO:0030332)
0.1 1.9 GO:0035198 miRNA binding(GO:0035198)
0.1 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 2.9 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 2.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 3.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 4.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 2.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 10.9 GO:0019901 protein kinase binding(GO:0019901)
0.1 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 2.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.2 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 4.8 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.1 4.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 5.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.2 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 1.2 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 2.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 7.9 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 1.2 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 1.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 8.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0002020 protease binding(GO:0002020)
0.0 0.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 9.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0044325 ion channel binding(GO:0044325)
0.0 5.8 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0046332 SMAD binding(GO:0046332)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 1.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.7 GO:0022843 voltage-gated cation channel activity(GO:0022843)
0.0 1.1 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 4.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 6.6 PID LKB1 PATHWAY LKB1 signaling events
0.2 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.2 2.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 7.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.0 PID FOXO PATHWAY FoxO family signaling
0.1 3.2 PID E2F PATHWAY E2F transcription factor network
0.1 2.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.7 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID ENDOTHELIN PATHWAY Endothelins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 3.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.4 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 2.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 5.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.3 2.9 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.3 4.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.3 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 3.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 2.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 3.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 1.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 3.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 3.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 4.5 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.1 2.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 3.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC