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Results for isl2a+isl2b

Z-value: 0.68

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Transcription factors associated with isl2a+isl2b

Gene Symbol Gene ID Gene Info
isl2a
ENSDARG00000003971 ISL LIM homeobox 2a
isl2b
ENSDARG00000053499 ISL LIM homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
isl2adr10_dc_chr25_-_32344881_323449400.087.7e-01Click!

Activity profile of isl2a+isl2b motif

Sorted Z-values of isl2a+isl2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of isl2a+isl2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_-_2677200 1.45 ENSDART00000063320
cldne
claudin e
chr6_-_37444877 1.29 ENSDART00000138351
cth
cystathionase (cystathionine gamma-lyase)
chr7_-_17129072 1.00

chr7_+_38895198 0.94 ENSDART00000052318
mdka
midkine a
chr25_-_22821132 0.94

chr20_-_475417 0.93 ENSDART00000032212
fynrk
fyn-related Src family tyrosine kinase
chr1_+_13779755 0.90

chr7_-_48392300 0.89

chr22_-_36561247 0.75 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_15425559 0.72 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr16_+_54350976 0.72 ENSDART00000172622
ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr16_+_4825019 0.72 ENSDART00000167665
LIN28A
lin-28 homolog A
chr18_+_17548213 0.71 ENSDART00000144960
nup93
nucleoporin 93
chr10_+_29964045 0.70 ENSDART00000118838
SNORD14
Small nucleolar RNA SNORD14
chr5_-_19357961 0.67 ENSDART00000088904
ENSDART00000163701
gltpa
glycolipid transfer protein a
chr9_+_2523927 0.65 ENSDART00000166326
si:ch73-167c12.2
si:ch73-167c12.2
chr17_+_1799209 0.64 ENSDART00000112183
cep170b
centrosomal protein 170B
chr3_-_26657213 0.59

chr19_-_5851328 0.57 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr11_-_44724371 0.55 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr24_+_35500964 0.55 ENSDART00000058571
snai2
snail family zinc finger 2
chr12_-_22438379 0.55 ENSDART00000177715
CR925753.1
ENSDARG00000108493
chr13_-_36265504 0.54 ENSDART00000140243
actn1
actinin, alpha 1
chr4_-_73485204 0.53 ENSDART00000122898
phf21b
PHD finger protein 21B
chr17_-_16414629 0.51 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr14_-_24094142 0.49 ENSDART00000126894
fam13b
family with sequence similarity 13, member B
chr21_-_8103907 0.48 ENSDART00000171027
OLFML2A
olfactomedin like 2A
chr16_-_48458505 0.48 ENSDART00000159372
eif3ha
eukaryotic translation initiation factor 3, subunit H, a
chr10_+_29963998 0.46 ENSDART00000118838
SNORD14
Small nucleolar RNA SNORD14
chr12_-_4497094 0.45 ENSDART00000163651
trpm4b.2
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr2_-_57133471 0.44

chr10_-_43924675 0.44 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr3_-_19218660 0.44 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr14_-_6831373 0.43 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr20_+_41123859 0.42 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr19_+_38834972 0.42 ENSDART00000140198
ENSDART00000033037
ENSDART00000035093
col9a2
procollagen, type IX, alpha 2
chr6_-_53227526 0.42 ENSDART00000160955
slc38a3b
solute carrier family 38, member 3b
chr24_-_14447773 0.42

chr8_+_28362311 0.41 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr14_-_33604914 0.41 ENSDART00000168546
zdhhc24
zinc finger, DHHC-type containing 24
chr23_-_43595189 0.41

chr13_+_516287 0.41 ENSDART00000172469
ENSDART00000168523
ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr13_+_516546 0.37 ENSDART00000172469
ENSDART00000168523
ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr16_-_17164459 0.37 ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr16_-_7876036 0.34 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr22_-_23518719 0.34 ENSDART00000161253
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr17_-_11312185 0.33 ENSDART00000091159
adpgk2
ADP-dependent glucokinase 2
chr17_+_43605118 0.33 ENSDART00000156271
cfap99
cilia and flagella associated protein 99
chr10_-_17264097 0.32 ENSDART00000134059
depdc5
DEP domain containing 5
chr20_-_54206786 0.32 ENSDART00000004756
hsp90aa1.1
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
chr19_+_16111610 0.32 ENSDART00000131319
ctps1a
CTP synthase 1a
chr4_-_17680826 0.31 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr20_+_22900165 0.31 ENSDART00000058527
scfd2
sec1 family domain containing 2
chr13_-_36265476 0.31 ENSDART00000133740
ENSDART00000100217
actn1
actinin, alpha 1
chr7_+_58007815 0.31 ENSDART00000179306
CR354540.2
ENSDARG00000106881
chr20_-_475321 0.30 ENSDART00000032212
fynrk
fyn-related Src family tyrosine kinase
chr10_+_29964164 0.29 ENSDART00000118838
SNORD14
Small nucleolar RNA SNORD14
chr12_+_19159234 0.28 ENSDART00000153428
tnrc6b
trinucleotide repeat containing 6b
chr9_-_32942783 0.26 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr12_-_28248133 0.26 ENSDART00000016283
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr21_+_25199691 0.24 ENSDART00000168140
ENSDART00000112783
tmem45b
transmembrane protein 45B
chr9_-_34691159 0.24 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr5_-_9162684 0.23

chr21_+_13196717 0.23 ENSDART00000163767
adora2ab
adenosine A2a receptor b
chr14_-_6831308 0.23 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr25_-_20933295 0.23 ENSDART00000138985
ENSDART00000046298
gnaia
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr13_+_516496 0.23 ENSDART00000172469
ENSDART00000168523
ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr8_-_52728470 0.22

chr7_-_5253397 0.22 ENSDART00000033316
vangl2
VANGL planar cell polarity protein 2
chr18_+_25743054 0.22

chr22_-_4867538 0.22 ENSDART00000081801
ncl1
nicalin
chr1_+_52157637 0.22 ENSDART00000123972
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr23_+_33792005 0.21 ENSDART00000024695
dazap2
DAZ associated protein 2
chr2_-_48203102 0.21

chr16_+_5492632 0.20

chr18_+_17594381 0.19 ENSDART00000010998
slc12a3
solute carrier family 12 (sodium/chloride transporter), member 3
chr3_+_3994248 0.19

chr3_+_19911730 0.19

chr22_-_10135735 0.19 ENSDART00000142012
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr5_-_31301280 0.19 ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr21_+_11656401 0.18 ENSDART00000102404
ell2
elongation factor, RNA polymerase II, 2
chr4_-_73485366 0.18 ENSDART00000122898
phf21b
PHD finger protein 21B
chr7_+_58718614 0.17 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr7_-_5366526 0.17

chr5_-_40894693 0.16 ENSDART00000051081
eef2l2
eukaryotic translation elongation factor 2, like 2
chr15_-_14616083 0.16 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr14_-_4038642 0.16 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr18_+_15964146 0.15

chr15_-_36490729 0.15

chr22_-_36561217 0.15 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr8_+_17479651 0.15

chr10_-_20545884 0.15

chr2_+_38390887 0.15 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr20_+_22900302 0.14 ENSDART00000131132
scfd2
sec1 family domain containing 2
chr3_+_32400841 0.14 ENSDART00000150981
nosip
nitric oxide synthase interacting protein
chr24_-_14447136 0.14

chr12_+_18777525 0.13 ENSDART00000105858
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr18_-_1347210 0.13 ENSDART00000171402
pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr8_-_49739908 0.13 ENSDART00000138810
gkap1
G kinase anchoring protein 1
chr19_+_46371192 0.12 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr11_+_11284030 0.12 ENSDART00000026814
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr6_+_7376428 0.12 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr13_-_33529333 0.12 ENSDART00000133073
rrbp1a
ribosome binding protein 1a
chr6_+_20402297 0.12

chr4_-_2370333 0.12 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr22_-_16128314 0.12 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr9_-_34691081 0.12 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr4_-_62022037 0.12

chr5_+_69013399 0.11 ENSDART00000162057
ENSDART00000166893
setd8b
SET domain containing (lysine methyltransferase) 8b
chr6_+_3556296 0.11 ENSDART00000041627
ssb
Sjogren syndrome antigen B (autoantigen La)
chr5_-_68712571 0.11 ENSDART00000109487
CABZ01032476.1
ENSDARG00000074645
chr12_+_22438908 0.10 ENSDART00000172066
polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr4_-_73485324 0.10 ENSDART00000122898
phf21b
PHD finger protein 21B
KN150123v1_-_37086 0.10

chr2_+_21267793 0.09 ENSDART00000099913
pla2g4aa
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr22_-_12905648 0.09 ENSDART00000157820
mfsd6a
major facilitator superfamily domain containing 6a
chr23_+_29956616 0.09 ENSDART00000148706
aurkaip1
aurora kinase A interacting protein 1
chr7_+_72030256 0.09 ENSDART00000172021
tollip
toll interacting protein
chr16_+_38251717 0.09 ENSDART00000044971
myo1eb
myosin IE, b
chr12_-_41128584 0.09

chr19_-_48327666 0.09

chr5_-_68712851 0.08 ENSDART00000109487
CABZ01032476.1
ENSDARG00000074645
chr25_+_1046304 0.07 ENSDART00000172662
fam96a
family with sequence similarity 96, member A
chr8_+_31707960 0.07 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr23_-_29952057 0.07 ENSDART00000058407
slc25a33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr7_+_8834138 0.07 ENSDART00000173250
pcsk6
proprotein convertase subtilisin/kexin type 6
chr12_-_3042545 0.06 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr13_-_36265415 0.05 ENSDART00000133740
ENSDART00000100217
actn1
actinin, alpha 1
chr5_+_31590746 0.05

chr7_-_48392412 0.05

KN149711v1_-_7827 0.05 ENSDART00000171410
ENSDARG00000104905
ENSDARG00000104905
chr3_+_28808901 0.05 ENSDART00000141904
ENSDART00000077221
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr12_+_24221087 0.04 ENSDART00000088178
nrxn1a
neurexin 1a
chr20_-_23272102 0.04 ENSDART00000167197
spata18
spermatogenesis associated 18
chr1_-_50215233 0.04 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr13_+_35402382 0.04 ENSDART00000163368
wdr27
WD repeat domain 27
chr2_-_55565099 0.03 ENSDART00000149062
rab8a
RAB8A, member RAS oncogene family
chr15_+_9351211 0.03 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr25_+_4729095 0.03 ENSDART00000163839
ap4e1
adaptor-related protein complex 4, epsilon 1 subunit
chr8_-_53593880 0.02 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr14_-_6831278 0.02 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr2_+_11094785 0.02 ENSDART00000091497
tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_+_53384116 0.02 ENSDART00000149760
triobpa
TRIO and F-actin binding protein a
chr20_+_40560443 0.02 ENSDART00000153119
serinc1
serine incorporator 1
chr6_-_16590883 0.02 ENSDART00000153552
nomo
nodal modulator
chr19_+_7505348 0.01 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr6_-_34854950 0.01 ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr7_-_57680717 0.01

chr20_+_36098607 0.01 ENSDART00000021456
opn5
opsin 5
chr19_+_46371377 0.00 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0019344 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.2 1.2 GO:0000012 single strand break repair(GO:0000012)
0.2 0.7 GO:0046931 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.1 0.4 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.1 0.3 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.3 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.4 GO:0015817 histidine transport(GO:0015817)
0.1 0.3 GO:0098900 regulation of action potential(GO:0098900)
0.1 0.2 GO:0045813 positive regulation of Wnt signaling pathway, calcium modulating pathway(GO:0045813)
0.1 0.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 1.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.3 GO:1903428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.9 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.3 GO:0019856 pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.3 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.1 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698) inflammatory response to wounding(GO:0090594)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.4 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.2 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.7 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008665 tRNA 2'-phosphotransferase activity(GO:0000215) 2'-phosphotransferase activity(GO:0008665)
0.2 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0015182 L-histidine transmembrane transporter activity(GO:0005290) L-asparagine transmembrane transporter activity(GO:0015182)
0.1 0.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0005035 death receptor activity(GO:0005035)
0.1 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.0 GO:0002039 p53 binding(GO:0002039)
0.1 0.2 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.0 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.7 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.9 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions