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Results for jdp2b_june_atf7a+atf7b_creb5b

Z-value: 0.66

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Transcription factors associated with jdp2b_june_atf7a+atf7b_creb5b

Gene Symbol Gene ID Gene Info
ENSDARG00000020133 Jun dimerization protein 2b
ENSDARG00000104090 JunE proto-oncogene, AP-1 transcription factor subunit
ENSDARG00000011298 activating transcription factor 7a
ENSDARG00000055481 activating transcription factor 7b
ENSDARG00000070536 cAMP responsive element binding protein 5b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
creb5bdr10_dc_chr16_-_20901879_209019340.702.8e-03Click!
atf7adr10_dc_chr23_-_27569482_275695080.601.5e-02Click!
jdp2bdr10_dc_chr20_+_46683031_466830380.486.2e-02Click!
atf7bdr10_dc_chr6_-_39633603_39633697-0.458.0e-02Click!

Activity profile of jdp2b_june_atf7a+atf7b_creb5b motif

Sorted Z-values of jdp2b_june_atf7a+atf7b_creb5b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of jdp2b_june_atf7a+atf7b_creb5b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_-_43611307 2.61 ENSDART00000151030
si:ch73-362m14.4
chr15_+_28753020 2.55 ENSDART00000155815
neuro-oncological ventral antigen 2
chr22_-_3747016 1.70 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr18_-_7184884 1.66 ENSDART00000135587
CD9 molecule a
chr16_+_5284778 1.63 ENSDART00000156685
ENSDART00000156765
SOGA family member 3a
SOGA family member 3a
chr5_-_23495973 1.53 ENSDART00000085969
MAP7 domain containing 2a
chr25_+_35179025 1.52 ENSDART00000149768
kinesin family member 21A
chr20_+_29840979 1.51 ENSDART00000101603
kinase D-interacting substrate 220b
chr20_-_24223659 1.51 ENSDART00000153464
BTB and CNC homology 1, basic leucine zipper transcription factor 2b
KN149932v1_+_27584 1.48

chr17_+_29328653 1.48 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr19_-_7306228 1.41 ENSDART00000104799
collagen, type XI, alpha 2
chr2_-_30340646 1.41 ENSDART00000099078
junctophilin 1b
chr7_-_14135850 1.40 ENSDART00000161442
ENSDARG00000101584
chr3_-_45420882 1.39 ENSDART00000161507
zgc:153426
chr5_+_55598181 1.38 ENSDART00000021159
LIM homeobox 1b
chr23_+_17856053 1.32 ENSDART00000154427
ENSDARG00000097211
chr23_-_7283514 1.28 ENSDART00000156369
ENSDARG00000096997
chr19_-_2011177 1.25 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_22170553 1.24 ENSDART00000139412
small integral membrane protein 18
chr12_+_48643983 1.23 ENSDART00000168441
zgc:165653
chr24_+_4341242 1.23 ENSDART00000133360
cyclin Y
chr5_+_64175669 1.22 ENSDART00000050863
zgc:101858
chr19_-_7306136 1.21 ENSDART00000133179
collagen, type XI, alpha 2
chr2_-_10555152 1.19 ENSDART00000150166
guanine nucleotide binding protein (G protein), gamma 12a
chr20_+_45531190 1.12

chr8_+_933677 1.09 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr10_-_11806373 1.07 ENSDART00000009715
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr18_-_7184699 1.06 ENSDART00000135587
CD9 molecule a
chr8_+_15201828 1.02 ENSDART00000132216
polyamine oxidase (exo-N4-amino) 1
chr13_+_17333810 0.99 ENSDART00000134181
ENSDARG00000093577
chr22_+_980836 0.98 ENSDART00000149743
peroxisome proliferator-activated receptor delta a
chr11_-_22211478 0.97 ENSDART00000065996
transmembrane protein 183A
chr23_-_5825236 0.96 ENSDART00000055087
pleckstrin homology-like domain, family A, member 3
chr21_+_25597814 0.94 ENSDART00000110705
transmembrane protein 151A
chr24_-_35897257 0.92

chr21_-_23271127 0.92 ENSDART00000007806
zinc finger and BTB domain containing 16a
chr9_+_54612545 0.92 ENSDART00000104475
thymosin, beta 4 x
chr3_-_6078015 0.91 ENSDART00000165715
ENSDARG00000098850
chr23_+_17856104 0.90 ENSDART00000154427
ENSDARG00000097211
chr8_-_23102555 0.89

chr9_-_296560 0.89 ENSDART00000160220
kinesin family member 5A, a
chr1_+_16681778 0.89

KN150672v1_-_47685 0.87

chr24_+_10276926 0.86 ENSDART00000145771
ENSDART00000157350
ENSDARG00000093108
chr19_-_39048324 0.86 ENSDART00000086717
collagen, type XVI, alpha 1
chr12_-_25110150 0.83 ENSDART00000077188
cytochrome c oxidase subunit VIIa polypeptide 3
chr13_-_40628582 0.82 ENSDART00000111641
ENSDART00000159255
MORN repeat containing 4
chr2_+_54665352 0.80

chr5_-_40894631 0.78 ENSDART00000121840
eukaryotic translation elongation factor 2, like 2
chr7_-_11812634 0.77 ENSDART00000101537
mex-3 RNA binding family member B
chr9_-_296499 0.75 ENSDART00000165228
kinesin family member 5A, a
chr5_+_69036145 0.73 ENSDART00000174403
fibronectin type III and SPRY domain containing 1-like
chr16_-_55234426 0.73 ENSDART00000078887
transmembrane protein 222a
chr25_+_34340139 0.73 ENSDART00000061996
transmembrane protein 231
chr25_-_32344881 0.72 ENSDART00000012862
ISL LIM homeobox 2a
chr3_-_6922811 0.70

chr15_+_657554 0.69 ENSDART00000156007
si:ch73-144d13.8
chr16_-_12282596 0.69 ENSDART00000110567
calsyntenin 3
chr22_+_20157574 0.68

chr4_+_70746956 0.68 ENSDART00000172228
si:ch211-161m3.2
chr21_+_22808694 0.67 ENSDART00000065555
baculoviral IAP repeat containing 2
chr9_-_13991784 0.65 ENSDART00000061156
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr16_+_34569479 0.65 ENSDART00000041007
stathmin 1b
chr22_-_26971466 0.65 ENSDART00000087202
ENSDARG00000061256
chr18_-_5749619 0.63 ENSDART00000161538
cytochrome P450, family 1, subfamily A
chr8_+_21556157 0.63 ENSDART00000172190
adherens junctions associated protein 1
chr22_-_15567180 0.62 ENSDART00000123125
tropomyosin 4a
chr2_+_289138 0.62 ENSDART00000157246
zinc finger protein 1008
chr20_-_32543497 0.61 ENSDART00000026635
nuclear receptor subfamily 2, group E, member 1
chr21_-_45341242 0.60 ENSDART00000075438
CDKN2A interacting protein N-terminal like
chr8_+_8673307 0.59 ENSDART00000110854
ELK1, member of ETS oncogene family
chr24_-_7602759 0.59 ENSDART00000041714
ATPase, H+ transporting, lysosomal V0 subunit a1b
chr3_-_3550073 0.57 ENSDART00000166667
transmembrane protein 184bb
chr12_-_48643687 0.57 ENSDART00000178135
ENSDART00000176040
ENSDARG00000107260
chr8_+_29733109 0.57 ENSDART00000020621
mitogen-activated protein kinase 4
chr13_-_40628537 0.56 ENSDART00000111641
ENSDART00000159255
MORN repeat containing 4
chr24_+_9163779 0.56

chr15_-_630492 0.56 ENSDART00000153884
si:ch73-144d13.5
chr14_-_49951676 0.55 ENSDART00000021736
short coiled-coil protein b
chr5_+_44722544 0.54 ENSDART00000084411
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr19_-_19931617 0.54 ENSDART00000160582
cAMP responsive element binding protein 5a
chr7_+_39957385 0.54 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr3_-_16263697 0.53 ENSDART00000130575
ENSDART00000136465
elongation factor Tu GTP binding domain containing 2
chr13_+_51663349 0.53

chr18_-_19114558 0.53 ENSDART00000177621
DENN/MADD domain containing 4A
chr23_+_24141576 0.52

chr23_+_25782195 0.52 ENSDART00000060059
RNA binding motif, single stranded interacting protein 2b
chr1_+_6862901 0.52 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr19_-_22184035 0.51

chr10_-_43289221 0.51 ENSDART00000148293
transmembrane protein 167A
chr4_+_71392976 0.50 ENSDART00000167082
zgc:152938
chr5_+_5186074 0.50

chr11_-_19414624 0.50 ENSDART00000157847
ataxin 7
chr12_-_36565562 0.50 ENSDART00000153259
si:ch211-216b21.2
chr23_+_34891575 0.49 ENSDART00000013449
carbohydrate sulfotransferase 13
KN150072v1_+_1751 0.49 ENSDART00000168431
ENSDARG00000102665
chr3_-_39208943 0.48

chr24_+_24309660 0.48

chr5_-_47519273 0.48

chr15_+_1832874 0.48 ENSDART00000126253
family with sequence similarity 124B
chr4_-_73559895 0.48 ENSDART00000162529
zgc:172139
chr14_+_16508093 0.48 ENSDART00000161201
LIM and calponin homology domains 1b
chr1_-_50831155 0.47 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr4_-_6365088 0.47 ENSDART00000140100
MyoD family inhibitor domain containing
chr3_+_43010408 0.47 ENSDART00000169061
ENSDARG00000099842
chr20_-_37733350 0.47

chr15_-_1070691 0.46 ENSDART00000153569
si:dkey-77f5.4
chr4_+_22754618 0.46

chr19_+_24340673 0.46

chr25_-_13057808 0.46 ENSDART00000172571
sphingomyelin phosphodiesterase 3, neutral
chr7_-_34656224 0.46 ENSDART00000073397
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3a
chr14_-_49115338 0.46 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr4_+_72559555 0.45

chr23_-_624534 0.45 ENSDART00000132175
neural adhesion molecule L1.1
chr7_+_16348702 0.45

chr24_+_192889 0.45 ENSDART00000067764
serine/threonine kinase 17a
chr11_+_42203807 0.45 ENSDART00000067604
ADP-ribosylation factor 4a
chr2_-_57133471 0.45

chr13_+_24271932 0.44 ENSDART00000043002
RAB1A, member RAS oncogene family b
chr17_-_5453357 0.44 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr11_+_3186396 0.44 ENSDART00000159459
premelanosome protein a
chr5_+_32282547 0.44 ENSDART00000135459
ribosomal protein L12
chr16_-_20901879 0.41 ENSDART00000103630
cAMP responsive element binding protein 5b
chr9_+_219478 0.41 ENSDART00000164048
ENSDART00000161484
ENSDART00000171623
mitogen-activated protein kinase kinase kinase 12
chr13_-_49153890 0.40 ENSDART00000136991
interferon regulatory factor 2 binding protein 2a
chr9_-_306569 0.40 ENSDART00000166059
si:ch211-166e11.5
chr7_-_12715948 0.40 ENSDART00000173115
ribosomal protein, large P2, like
chr4_-_25282256 0.40 ENSDART00000066936
transmembrane protein 110, like
chr9_-_6524104 0.40 ENSDART00000158468
NCK adaptor protein 2a
chr5_-_40894693 0.39 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr4_-_38423096 0.39

chr13_-_31339870 0.39 ENSDART00000076574
reticulon 1a
chr7_-_73866202 0.39

chr5_+_64175494 0.39 ENSDART00000050863
zgc:101858
chr20_-_34898276 0.39 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr13_+_28574593 0.38 ENSDART00000126845
LIM domain binding 1a
chr17_-_47893203 0.38

chr25_+_7147666 0.38 ENSDART00000104712
high mobility group 20A
chr4_-_71335661 0.37

chr7_+_20377678 0.37 ENSDART00000173710
si:dkey-19b23.15
chr9_+_31469848 0.37

chr17_+_22936598 0.37 ENSDART00000155145
latent transforming growth factor beta binding protein 1
chr11_+_44460956 0.37 ENSDART00000168531
interferon regulatory factor 2 binding protein 2b
chr6_+_15018104 0.37 ENSDART00000063648
NCK adaptor protein 2b
chr23_+_19827551 0.37 ENSDART00000073442
filamin A, alpha (actin binding protein 280)
chr23_+_29431173 0.36 ENSDART00000027255
TAR DNA binding protein, like
chr25_-_14573221 0.36

chr5_-_31763197 0.36 ENSDART00000098045
growth arrest-specific 1b
chr17_-_26893412 0.36 ENSDART00000045842
regulator of calcineurin 3
chr2_+_48448974 0.36 ENSDART00000023040
hes family bHLH transcription factor 6
chr4_-_28651054 0.36 ENSDART00000167212
ENSDARG00000104584
chr22_+_2606049 0.35

chr10_-_9256025 0.35 ENSDART00000140830
ADP-ribosylation factor-like 15b
chr17_+_1610578 0.35 ENSDART00000082101
protein phosphatase 2, regulatory subunit B', gamma a
chr10_-_40905193 0.35 ENSDART00000172089
proliferating cell nuclear antigen
chr22_+_12327849 0.34 ENSDART00000178678
ENSDARG00000106890
chr10_+_28420109 0.34 ENSDART00000142016
peptidyl-tRNA hydrolase 2
chr3_+_33168814 0.33 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr4_-_72183874 0.33 ENSDART00000144382
si:dkey-262g12.12
chr4_-_71322276 0.33

chr6_+_27156169 0.33 ENSDART00000088364
kinesin family member 1Aa
chr8_-_410733 0.33 ENSDART00000151255
tripartite motif containing 36
chr2_-_54965656 0.33

chr4_-_1989775 0.33 ENSDART00000003790
PWP1 homolog (S. cerevisiae)
chr9_+_48521741 0.33 ENSDART00000145972
coiled-coil domain containing 173
chr17_-_5453436 0.33 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr3_-_36130248 0.33 ENSDART00000126588
ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3)
chr6_+_7092350 0.33 ENSDART00000049695
ENSDART00000136088
ENSDART00000083424
ENSDART00000125912
DAZ interacting zinc finger protein 1
chr2_+_23038657 0.33 ENSDART00000089012
kinesin family member 1Ab
chr23_-_45356039 0.33 ENSDART00000067630
ENSDARG00000039901
chr11_-_43860836 0.32 ENSDART00000047126
chloride channel, voltage-sensitive 4
chr5_+_2384929 0.32

chr18_+_12089333 0.32 ENSDART00000112671
bicaudal D homolog 1a
chr25_+_16849382 0.32 ENSDART00000016591
fibroblast growth factor 6a
chr20_-_9474672 0.32 ENSDART00000152674
ENSDARG00000033201
chr4_-_25282161 0.31 ENSDART00000066936
transmembrane protein 110, like
chr14_-_24463906 0.31 ENSDART00000126199
slit homolog 3 (Drosophila)
chr4_+_12980657 0.31

chr13_+_371940 0.31 ENSDART00000013007
delta(4)-desaturase, sphingolipid 1
chr7_+_39934376 0.31 ENSDART00000173742
non-SMC condensin II complex, subunit G2
chr20_-_54742983 0.31

chr16_-_32695903 0.31 ENSDART00000136161
failed axon connections homolog b
chr3_-_6922655 0.31

chr19_-_39048402 0.30 ENSDART00000086717
collagen, type XVI, alpha 1
chr17_+_12544451 0.30 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr5_+_29489543 0.30 ENSDART00000078114
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr14_+_905613 0.30 ENSDART00000111141
myozenin 3a
chr16_-_9978112 0.30 ENSDART00000149312
neurocalcin delta a
chr4_-_71367238 0.29 ENSDART00000165327
ENSDARG00000100390
chr23_-_4979524 0.29 ENSDART00000060714
ATPase, H+ transporting, lysosomal accessory protein 1a
chr5_+_71360122 0.29

chr5_+_43365449 0.29 ENSDART00000113502
si:dkey-84j12.1
chr9_+_7570199 0.29 ENSDART00000081543
protein tyrosine phosphatase, receptor type, Na
chr21_-_36886505 0.29 ENSDART00000113678
WW and C2 domain containing 1
chr25_+_19103272 0.29 ENSDART00000067323
hyaluronan and proteoglycan link protein 3
chr4_+_119964 0.29 ENSDART00000177177
ENSDART00000159996
TANK-binding kinase 1
chr4_-_1564624 0.29 ENSDART00000168633
BICD cargo adaptor 1
chr24_+_37752791 0.29 ENSDART00000158181
WD repeat domain 24
chr3_+_31802145 0.28 ENSDART00000139644
lin-7 homolog B (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1990535 neuron projection maintenance(GO:1990535)
0.3 1.3 GO:0030219 megakaryocyte differentiation(GO:0030219) positive regulation of myeloid cell differentiation(GO:0045639)
0.2 1.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988) synaptic membrane adhesion(GO:0099560)
0.2 1.0 GO:0030194 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.9 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.2 2.6 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 1.2 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.2 0.7 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.2 0.5 GO:2001017 regulation of retrograde axon cargo transport(GO:2001017)
0.1 0.4 GO:0097435 fibril organization(GO:0097435)
0.1 0.7 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.8 GO:0051965 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0014005 microglia development(GO:0014005)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.6 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.5 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.3 GO:0032475 otolith formation(GO:0032475)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.4 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.4 GO:0002762 negative regulation of myeloid leukocyte differentiation(GO:0002762)
0.1 0.3 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.1 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.2 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.2 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.1 0.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 2.6 GO:0007338 single fertilization(GO:0007338)
0.1 0.5 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.5 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 3.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.4 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0050864 regulation of B cell activation(GO:0050864)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0061323 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.0 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 2.1 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.2 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 2.8 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0015671 response to activity(GO:0014823) oxygen transport(GO:0015671)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 0.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.4 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.9 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 1.1 GO:0033993 response to lipid(GO:0033993)
0.0 0.6 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0030834 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) negative regulation of protein complex disassembly(GO:0043242) actin filament capping(GO:0051693) regulation of protein depolymerization(GO:1901879) negative regulation of protein depolymerization(GO:1901880)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0030314 junctional membrane complex(GO:0030314)
0.2 2.6 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0016460 myosin II complex(GO:0016460)
0.1 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 3.7 GO:0005871 kinesin complex(GO:0005871)
0.1 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.5 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 1.3 GO:0030141 secretory granule(GO:0030141)
0.0 3.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0046592 polyamine oxidase activity(GO:0046592)
0.3 2.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 0.8 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 0.6 GO:0070330 aromatase activity(GO:0070330)
0.2 2.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 3.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 1.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 3.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.1 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 ST ADRENERGIC Adrenergic Pathway
0.0 1.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1