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Results for junba+junbb

Z-value: 0.78

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Transcription factors associated with junba+junbb

Gene Symbol Gene ID Gene Info
ENSDARG00000074378 JunB proto-oncogene, AP-1 transcription factor subunit a
ENSDARG00000104773 JunB proto-oncogene, AP-1 transcription factor subunit b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
junbadr10_dc_chr1_-_51100156_511001630.097.5e-01Click!

Activity profile of junba+junbb motif

Sorted Z-values of junba+junbb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of junba+junbb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr13_-_49749441 1.06 ENSDART00000136165
lysosomal trafficking regulator
chr1_+_6862901 0.97 ENSDART00000015732
myosin, light polypeptide 3, skeletal muscle
chr9_+_219478 0.95 ENSDART00000164048
ENSDART00000161484
ENSDART00000171623
mitogen-activated protein kinase kinase kinase 12
chr9_-_39195468 0.93 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr17_+_1610578 0.92 ENSDART00000082101
protein phosphatase 2, regulatory subunit B', gamma a
chr3_+_33168814 0.78 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr23_+_44817648 0.66 ENSDART00000143688
discs, large homolog 4b (Drosophila)
chr23_-_7283514 0.62 ENSDART00000156369
ENSDARG00000096997
chr20_+_35010140 0.61 ENSDART00000172001
synaptosomal-associated protein, 25a
chr13_-_49749469 0.61 ENSDART00000136165
lysosomal trafficking regulator
chr17_+_25163592 0.59 ENSDART00000100277
CLN8, transmembrane ER and ERGIC protein
chr22_+_18228143 0.59 ENSDART00000141535
ENSDARG00000095557
chr13_-_47266563 0.58 ENSDART00000131239
acyl-CoA oxidase-like
chr9_+_4188263 0.57 ENSDART00000164543
kalirin RhoGEF kinase a
chr6_+_10098305 0.57 ENSDART00000151477
cordon-bleu WH2 repeat protein-like 1a
chr17_-_12231165 0.57 ENSDART00000080927
synaptosomal-associated protein, 25b
chr22_-_38635149 0.56 ENSDART00000098330
natriuretic peptide C
chr25_-_22955066 0.56 ENSDART00000024633
dual specificity phosphatase 8a
chr2_+_23038657 0.55 ENSDART00000089012
kinesin family member 1Ab
chr11_-_18074946 0.53

chr11_+_3186396 0.52 ENSDART00000159459
premelanosome protein a
chr1_-_22170553 0.51 ENSDART00000139412
small integral membrane protein 18
chr8_-_14113377 0.50 ENSDART00000090427
si:dkey-6n6.1
chr2_-_42566339 0.50 ENSDART00000121452
solute carrier organic anion transporter family member 5A1b
chr13_+_15685540 0.50 ENSDART00000137061
kinesin light chain 1a
chr2_+_10023967 0.49 ENSDART00000148227
annexin A13, like
chr5_+_53854279 0.49 ENSDART00000165889
taperin
chr12_-_308929 0.49 ENSDART00000066579
ENSDART00000171396
6-pyruvoyltetrahydropterin synthase
chr17_+_25168837 0.49 ENSDART00000148431
CLN8, transmembrane ER and ERGIC protein
chr3_+_32272097 0.48 ENSDART00000156982
si:ch211-195b15.8
chr25_-_36512943 0.48 ENSDART00000114508
hypoxanthine phosphoribosyltransferase 1, like
chr5_+_8542777 0.47 ENSDART00000091463
iduronidase, alpha-L-
chr1_+_31131899 0.47 ENSDART00000075260
internexin neuronal intermediate filament protein, alpha b
chr21_-_43611307 0.46 ENSDART00000151030
si:ch73-362m14.4
chr18_+_8959686 0.45 ENSDART00000145226
si:ch211-233h19.2
chr7_-_8635687 0.43 ENSDART00000081620
ventral anterior homeobox 2
chr17_+_50577102 0.42 ENSDART00000127374
DDHD domain containing 1a
chr12_-_17585587 0.41 ENSDART00000142427
parvalbumin 3
chr13_-_24248675 0.41 ENSDART00000046360
ras homolog family member Ua
chr5_-_23495973 0.41 ENSDART00000085969
MAP7 domain containing 2a
chr19_+_16318256 0.40 ENSDART00000137189
protein tyrosine phosphatase, receptor type, U, a
chr14_+_23631214 0.40 ENSDART00000172149
SH3 domain containing ring finger 2
chr19_+_46380082 0.40 ENSDART00000158781
si:ch211-153f2.7
chr5_-_47519273 0.39

chr23_-_7889744 0.39 ENSDART00000164117
myelin transcription factor 1b
chr5_+_32314200 0.39 ENSDART00000051336
cysteine-rich, angiogenic inducer 61 like 1
chr3_+_43010408 0.38 ENSDART00000169061
ENSDARG00000099842
chr23_+_28656263 0.38 ENSDART00000020296
neural adhesion molecule L1.2
chr23_-_624534 0.38 ENSDART00000132175
neural adhesion molecule L1.1
chr15_+_36197093 0.38 ENSDART00000156697
collagen, type IV, alpha 3
chr17_+_12544451 0.37 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr19_-_10635235 0.37 ENSDART00000104539
lens intrinsic membrane protein 2.4
chr5_+_19802818 0.37

chr3_-_39208943 0.37

chr14_+_905613 0.36 ENSDART00000111141
myozenin 3a
chr22_+_12327849 0.36 ENSDART00000178678
ENSDARG00000106890
chr20_-_52133924 0.36 ENSDART00000074325
dual specificity phosphatase 10
chr14_-_41101660 0.35 ENSDART00000003170
MID1 interacting protein 1, like
chr7_-_51474531 0.35 ENSDART00000083190
histone deacetylase 8
chr8_-_9081109 0.34 ENSDART00000176850
solute carrier family 6 (neurotransmitter transporter), member 8
chr7_-_57727148 0.34

chr18_+_10815994 0.34 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr23_-_30858769 0.34 ENSDART00000131285
myelin transcription factor 1a
chr6_-_36817224 0.34 ENSDART00000160669
optic atrophy 1 (autosomal dominant)
chr6_+_27156169 0.34 ENSDART00000088364
kinesin family member 1Aa
chr11_-_7310284 0.34 ENSDART00000091664
adenomatosis polyposis coli 2
chr18_+_10815958 0.34 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr20_+_3095763 0.33 ENSDART00000133435
centrosomal protein 170B
chr22_+_30381331 0.33 ENSDART00000104751
max interactor 1, dimerization protein
chr9_-_55878647 0.33

chr23_+_19827551 0.33 ENSDART00000073442
filamin A, alpha (actin binding protein 280)
chr22_+_748767 0.32 ENSDART00000125347
cryptochrome circadian clock 1bb
chr5_+_71367929 0.32 ENSDART00000149910
c-abl oncogene 1, non-receptor tyrosine kinase
chr5_+_36250811 0.32 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr6_+_33261144 0.32 ENSDART00000157428
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr15_-_36196994 0.32 ENSDART00000163061
collagen, type IV, alpha 4
chr19_-_30816780 0.32 ENSDART00000103475
anterior gradient 2
chr10_-_26782374 0.31 ENSDART00000162710
fibroblast growth factor 13b
chr18_+_1018614 0.31 ENSDART00000161206
pyruvate kinase, muscle, a
chr20_+_54762145 0.31 ENSDART00000166592
ENSDARG00000102965
chr17_-_52735250 0.31

chr21_+_25017684 0.30 ENSDART00000065132
zgc:171740
chr22_+_38928192 0.30 ENSDART00000133067
ENSDART00000085701
ENSDARG00000095689
SUMO1/sentrin specific peptidase 5
chr5_+_26840147 0.30 ENSDART00000064701
lysyl oxidase-like 2b
chr12_-_10474942 0.30 ENSDART00000106163
ENSDART00000124562
zgc:152977
chr8_+_28046911 0.29 ENSDART00000078533
potassium voltage-gated channel, Shal-related subfamily, member 3
chr7_+_23636549 0.29 ENSDART00000045479
synaptotagmin IV
chr10_+_32702525 0.29 ENSDART00000137244
zinc finger and BTB domain containing 21
chr1_-_50962689 0.29 ENSDART00000130828
cannabinoid receptor interacting protein 1a
chr1_-_24297477 0.28

chr7_-_21978889 0.28

chr3_+_14314116 0.28 ENSDART00000170927
calponin 1, basic, smooth muscle, b
chr8_+_51721225 0.28 ENSDART00000129372
kelch-like family member 22
chr12_-_18981467 0.28 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr12_-_17079132 0.28 ENSDART00000020541
lipase, gastric
chr1_-_54269904 0.28 ENSDART00000129710
cartilage acidic protein 1a
chr15_-_28267088 0.27 ENSDART00000004200
sterile alpha and TIR motif containing 1
chr8_-_14446883 0.27 ENSDART00000057644
LIM homeobox 4
chr6_+_27676752 0.27 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr13_-_22943797 0.27 ENSDART00000143210
serglycin
chr10_+_5688293 0.27 ENSDART00000172632
peptidylglycine alpha-amidating monooxygenase
chr2_+_35505943 0.27 ENSDART00000131248
ENSDARG00000094295
chr6_-_18891908 0.27 ENSDART00000074327
insulin-like growth factor binding protein 2a
chr3_-_22083446 0.26 ENSDART00000154818
microtubule-associated protein tau b
chr8_-_27839244 0.26 ENSDART00000136562
CTTNBP2 N-terminal like b
chr4_-_16356071 0.26 ENSDART00000079521
keratocan
chr20_-_34898276 0.26 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr11_+_24826881 0.26 ENSDART00000157435
ndrg family member 3a
chr23_-_624480 0.26 ENSDART00000132175
neural adhesion molecule L1.1
chr7_-_8635989 0.26 ENSDART00000081620
ventral anterior homeobox 2
chr24_-_3751435 0.26 ENSDART00000139596
adenosine deaminase, RNA-specific, B2 (non-functional)
chr17_-_22552999 0.26 ENSDART00000141523
exonuclease 1
chr19_-_39048324 0.26 ENSDART00000086717
collagen, type XVI, alpha 1
chr23_+_12225922 0.26 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr25_+_16849382 0.25 ENSDART00000016591
fibroblast growth factor 6a
chr8_-_38126693 0.25 ENSDART00000112331
adhesion G protein-coupled receptor A2
chr9_+_21725007 0.25 ENSDART00000045093
Rho guanine nucleotide exchange factor (GEF) 7a
chr22_+_26737422 0.25

chr1_-_45941709 0.25 ENSDART00000053232
cytidine and dCMP deaminase domain containing 1
chr2_-_43318809 0.25 ENSDART00000132588
cAMP responsive element modulator a
KN150199v1_+_10711 0.25

chr12_+_44829938 0.25 ENSDART00000098932
WW domain binding protein 2
chr4_-_12915292 0.24 ENSDART00000067135
methionine sulfoxide reductase B3
chr3_-_45420882 0.24 ENSDART00000161507
zgc:153426
chr12_+_32936230 0.24 ENSDART00000153146
RNA binding protein, fox-1 homolog (C. elegans) 3a
chr18_-_6336677 0.24 ENSDART00000169844
IQ motif and Sec7 domain 3b
chr21_-_4530904 0.24 ENSDART00000031425
zgc:55582
chr22_+_30097988 0.24 ENSDART00000040538
adducin 3 (gamma) a
chr22_+_24596299 0.24 ENSDART00000158303
ENSDART00000160924
mucolipin 2
chr12_+_31523147 0.24 ENSDART00000153129
dynamin binding protein
chr25_-_8475902 0.24 ENSDART00000176751
ENSDARG00000107886
chr20_-_39200252 0.23 ENSDART00000037318
ENSDART00000143379
regulator of calcineurin 2
chr19_-_10476653 0.23 ENSDART00000109488
zgc:194578
chr2_-_16548451 0.23 ENSDART00000152031
Rho guanine nucleotide exchange factor (GEF) 4
chr20_-_37733350 0.23

chr15_-_34560555 0.23 ENSDART00000147582
alkylglycerol monooxygenase
chr11_-_80746 0.23

chr13_+_30033024 0.23 ENSDART00000040926
eukaryotic translation initiation factor 4E binding protein 2
chr14_-_30739765 0.23 ENSDART00000173282
muscleblind-like splicing regulator 3
chr20_-_18836593 0.23 ENSDART00000142837
ectonucleotide pyrophosphatase/phosphodiesterase 5
KN150108v1_+_18276 0.23

chr3_-_36130248 0.23 ENSDART00000126588
ras-related C3 botulinum toxin substrate 3a (rho family, small GTP binding protein Rac3)
chr11_+_19894390 0.22 ENSDART00000103997
FEZ family zinc finger 2
chr7_-_37283894 0.22 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr13_-_49707003 0.22

chr9_+_16437408 0.22 ENSDART00000006787
eph receptor A3
chr12_+_19183576 0.22 ENSDART00000066391
casein kinase 1, epsilon
chr4_+_70728870 0.22 ENSDART00000122809
si:ch211-161m3.2
chr9_+_31204464 0.22

chr8_+_50202152 0.22 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr23_+_19728953 0.22 ENSDART00000104441
abhydrolase domain containing 6b
chr9_+_21911860 0.22 ENSDART00000102021
SRY (sex determining region Y)-box 1a
chr13_+_1484997 0.22

chr22_+_18762028 0.22 ENSDART00000105399
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr19_-_7069850 0.22 ENSDART00000145741
zinc finger protein 384 like
chr25_-_36513113 0.21 ENSDART00000025494
hypoxanthine phosphoribosyltransferase 1, like
chr10_+_20435265 0.21 ENSDART00000160803
R3H domain and coiled-coil containing 1
chr18_+_16759954 0.21 ENSDART00000061265
ring finger protein 141
chr6_+_54857805 0.21

chr8_+_50201986 0.21 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr25_+_23494481 0.21 ENSDART00000089199
carnitine palmitoyltransferase 1Ab (liver)
chr14_-_26999410 0.21 ENSDART00000159727
protocadherin 11
chr21_+_28710341 0.21 ENSDART00000014058
zgc:100829
chr13_-_36420228 0.21

chr2_+_26273986 0.21 ENSDART00000137746
solute carrier family 7, member 14a
chr18_-_12483329 0.21 ENSDART00000092522
si:ch211-1e14.1
chr10_+_1384178 0.21 ENSDART00000150096
glial cell derived neurotrophic factor a
chr23_+_17294623 0.21 ENSDART00000054761
nucleolar protein 4-like b
chr25_-_19889225 0.21

chr6_-_36817334 0.21 ENSDART00000161928
optic atrophy 1 (autosomal dominant)
chr14_+_34146377 0.21 ENSDART00000131861
thymosin beta 2
chr12_-_292556 0.21 ENSDART00000152608
ENSDARG00000079888
chr15_+_36196988 0.20 ENSDART00000156697
collagen, type IV, alpha 3
chr4_+_9477541 0.20 ENSDART00000030738
lipase maturation factor 2b
chr11_-_16067646 0.20

chr10_+_32160464 0.20 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr9_-_41705830 0.20 ENSDART00000135821
major facilitator superfamily domain containing 6b
chr18_-_21116872 0.20 ENSDART00000100791
si:dkey-12e7.1
chr22_-_10574773 0.20 ENSDART00000091777
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr12_+_14040873 0.20 ENSDART00000078033
ENSDARG00000055642
chr9_+_34623833 0.20 ENSDART00000175455
si:ch211-269e2.1
chr10_+_20299071 0.20 ENSDART00000111097
chromosome 8 open reading frame 4
chr6_+_33552572 0.20 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr17_-_7990960 0.19

chr25_-_22954929 0.19 ENSDART00000024633
dual specificity phosphatase 8a
chr9_+_41776713 0.19

chr25_+_30627892 0.19

chr15_-_8333117 0.19 ENSDART00000061351
tumor necrosis factor receptor superfamily, member 19
chr22_+_38928297 0.19 ENSDART00000133067
ENSDART00000085701
ENSDARG00000095689
SUMO1/sentrin specific peptidase 5
chr3_-_23340407 0.19 ENSDART00000113135
ENSDART00000166068
male-specific lethal 1 homolog a (Drosophila)
chr5_-_9035835 0.19 ENSDART00000160079
cyclin G associated kinase
chr21_-_35048238 0.19 ENSDART00000146454
adrenoceptor beta 2, surface b
chr25_-_26449722 0.19 ENSDART00000006709
dihydrolipoamide dehydrogenase
chr15_-_41732304 0.19 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr10_+_32739166 0.19 ENSDART00000063551
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr8_+_52429114 0.19 ENSDART00000021604
GINS complex subunit 4 (Sld5 homolog)
chr21_+_26954483 0.19 ENSDART00000065397
FK506 binding protein 2
chr19_-_35688014 0.19

KN150475v1_+_6489 0.19

chr9_+_7019681 0.19 ENSDART00000135576
inositol polyphosphate-4-phosphatase type I Aa

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.2 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 0.5 GO:0097435 fibril organization(GO:0097435)
0.2 0.7 GO:0046100 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine metabolic process(GO:0046098) guanine biosynthetic process(GO:0046099) hypoxanthine metabolic process(GO:0046100)
0.2 0.5 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.4 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 1.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.4 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 1.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.3 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0060544 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.2 GO:0098810 neurotransmitter uptake(GO:0001504) phasic smooth muscle contraction(GO:0014821) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.1 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.2 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.3 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 0.5 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 0.2 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.1 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.7 GO:1902253 regulation of retinal ganglion cell axon guidance(GO:0090259) regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902253) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.1 0.3 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 1.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.3 GO:0099541 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0060031 protein catabolic process in the vacuole(GO:0007039) mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0046661 development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.0 1.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.5 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0036073 perichondral ossification(GO:0036073)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.1 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 0.5 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:0035552 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.3 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.8 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1902803 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) regulation of synaptic vesicle transport(GO:1902803)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:2001045 regulation of integrin-mediated signaling pathway(GO:2001044) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.3 GO:0015844 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) monoamine transport(GO:0015844) dopamine transport(GO:0015872) catecholamine secretion(GO:0050432) regulation of catecholamine secretion(GO:0050433) catecholamine transport(GO:0051937) regulation of amine transport(GO:0051952)
0.0 0.1 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.1 GO:0033146 intracellular estrogen receptor signaling pathway(GO:0030520) regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.3 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.0 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.2 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.4 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.3 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.5 GO:0051261 actin filament depolymerization(GO:0030042) protein depolymerization(GO:0051261)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005883 neurofilament(GO:0005883)
0.1 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.0 GO:0016234 inclusion body(GO:0016234)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.7 GO:0052657 guanine phosphoribosyltransferase activity(GO:0052657)
0.2 0.5 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.1 0.6 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.8 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.1 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:1901611 phosphatidic acid binding(GO:0070300) phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.4 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.3 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.2 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635) calcitonin receptor activity(GO:0004948) calcitonin family receptor activity(GO:0097642)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.1 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.9 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004935 adrenergic receptor activity(GO:0004935)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.7 GO:0071949 FAD binding(GO:0071949)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.0 GO:0035515 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.0 GO:0034713 transforming growth factor beta receptor activity, type II(GO:0005026) type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.6 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185) modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 1.4 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation