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DANIO-CODE

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Results for klf12a

Z-value: 0.78

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Transcription factors associated with klf12a

Gene Symbol Gene ID Gene Info
ENSDARG00000015312 Kruppel-like factor 12a

Activity profile of klf12a motif

Sorted Z-values of klf12a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_53568814 1.73 ENSDART00000154189
RNA binding motif protein 24b
chr14_+_6742208 1.18 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr23_-_31719203 1.14 ENSDART00000148122
serum/glucocorticoid regulated kinase 1
chr8_-_410733 1.07 ENSDART00000151255
tripartite motif containing 36
chr8_+_23192085 1.05 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr13_-_49886891 1.04 ENSDART00000074230
protein kinase containing Z-DNA binding domains
chr13_-_36495730 0.92 ENSDART00000165629
cyclin-dependent kinase inhibitor 3
chr17_-_18878230 0.88 ENSDART00000028044
galactosylceramidase b
chr22_+_818795 0.82 ENSDART00000003325
DENN/MADD domain containing 2Db
chr25_+_7318688 0.82 ENSDART00000166496
catalase
chr3_-_52644257 0.75 ENSDART00000128223
coiled-coil-helix-coiled-coil-helix domain containing 5
chr5_+_2472901 0.75 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr3_+_54551887 0.75 ENSDART00000169663
ENSDARG00000098327
chr8_-_32376710 0.70 ENSDART00000098850
lipase, endothelial
chr23_-_17503357 0.68 ENSDART00000043076
pancreatic progenitor cell differentiation and proliferation factor b
chr25_+_5995507 0.66 ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr2_+_25904910 0.66 ENSDART00000133623
phospholipase D1a
chr23_+_30971437 0.65 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr16_-_17289585 0.63 ENSDART00000135146
glyceraldehyde-3-phosphate dehydrogenase
chr20_-_15205171 0.63 ENSDART00000034011
flavin containing monooxygenase 5
chr17_+_25314291 0.63 ENSDART00000082319
transmembrane protein 54a
chr10_-_34058331 0.62 ENSDART00000046599
zygote arrest 1-like
chr10_+_19597171 0.62 ENSDART00000063810
ENSDART00000063806
ATPase, H+ transporting, lysosomal, V1 subunit B2
chr22_+_24596299 0.61 ENSDART00000158303
ENSDART00000160924
mucolipin 2
chr19_+_47698663 0.60 ENSDART00000161845
ENSDART00000078382
ENSDART00000158262
thiopurine S-methyltransferase, tandem duplicate 1
chr19_+_46523185 0.59 ENSDART00000159331
RNA binding motif protein 24a
chr16_-_26258657 0.57 ENSDART00000157787
lipase, hormone-sensitive b
chr14_+_11803542 0.57 ENSDART00000121913
potassium channel tetramerisation domain containing 12b
chr6_+_41506220 0.56 ENSDART00000136538
cytokine inducible SH2-containing protein
chr10_+_40031949 0.56 ENSDART00000009857
ENSDARG00000003145
chr9_+_30610756 0.55 ENSDART00000145025
zgc:113314
chr13_-_33562119 0.54 ENSDART00000143945
ENSDART00000100504
zgc:163030
chr10_+_7678087 0.53 ENSDART00000160673
histidine triad nucleotide binding protein 1
chr21_-_13759788 0.52 ENSDART00000102197
family with sequence similarity 129, member Ba
chr6_+_18024734 0.52 ENSDART00000067560
acyl-CoA oxidase 1, palmitoyl
chr25_+_25642475 0.51 ENSDART00000108476
leucine rich repeat containing 61
chr5_+_36250811 0.50 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr10_-_42302932 0.50 ENSDART00000076693
ENSDART00000073631
STAM binding protein a
chr5_-_11530880 0.49 ENSDART00000159896
GATS protein-like 3
chr10_-_20681689 0.49

chr7_-_3332675 0.48

chr7_-_58427369 0.48 ENSDART00000149347
coiled-coil-helix-coiled-coil-helix domain containing 7
chr11_+_44909949 0.48 ENSDART00000173116
ENSDART00000167011
ENSDART00000167226
pyrroline-5-carboxylate reductase 1b
chr11_-_40383013 0.48 ENSDART00000112140
family with sequence similarity 213, member B
chr21_-_32027717 0.47 ENSDART00000131651
ENSDARG00000073961
chr14_-_136402 0.46

chr11_-_11317608 0.46 ENSDART00000113311
collagen, type IX, alpha 1a
chr17_-_7635061 0.46 ENSDART00000064655
zinc finger and BTB domain containing 2a
chr11_-_26595578 0.46 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr21_+_21242470 0.45 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr18_+_38210277 0.45 ENSDART00000052703
nucleobindin 2b
chr11_-_34314863 0.45 ENSDART00000133302
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr22_-_3747016 0.44 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr17_+_25314229 0.44 ENSDART00000082319
transmembrane protein 54a
chr9_-_28588288 0.44 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr6_+_41506350 0.44 ENSDART00000136538
cytokine inducible SH2-containing protein
chr7_-_58856734 0.44 ENSDART00000159285
HAUS augmin-like complex, subunit 6
chr18_-_6336677 0.44 ENSDART00000169844
IQ motif and Sec7 domain 3b
chr7_+_38690837 0.44 ENSDART00000173565
diacylglycerol kinase, zeta a
chr15_-_19192862 0.43 ENSDART00000152428
Rho GTPase activating protein 32a
chr25_+_25642290 0.43 ENSDART00000108476
leucine rich repeat containing 61
chr7_-_58856862 0.43 ENSDART00000164104
HAUS augmin-like complex, subunit 6
chr11_+_29543388 0.43 ENSDART00000067822
dynein, light chain, Tctex-type 3
chr7_+_38490753 0.43 ENSDART00000036461
Rho GTPase activating protein 1
chr11_+_25063081 0.42

chr20_-_43889302 0.42 ENSDART00000004601
lysosomal protein transmembrane 4 alpha
chr7_-_58856806 0.42 ENSDART00000159285
HAUS augmin-like complex, subunit 6
chr2_+_30932612 0.41 ENSDART00000132450
ENSDART00000137012
myomesin 1a (skelemin)
chr1_+_45230899 0.41 ENSDART00000033669
lipoyltransferase 1
chr16_+_19831573 0.41 ENSDART00000135359
metastasis associated in colon cancer 1
chr8_-_4562273 0.40 ENSDART00000025535
septin 5a
chr5_-_9320252 0.40 ENSDART00000169698
zgc:158343
chr7_-_73592082 0.40 ENSDART00000160951
histone 1, H4, like
chr10_+_3299541 0.40 ENSDART00000031121
ENSDARG00000021564
KN149795v1_-_10712 0.39

chr13_-_36496048 0.39 ENSDART00000057155
cyclin-dependent kinase inhibitor 3
chr25_+_18910528 0.39 ENSDART00000104420
SAMM50 sorting and assembly machinery component
chr19_+_30266913 0.38 ENSDART00000109729
si:ch73-130a3.4
chr6_+_41506504 0.37 ENSDART00000084861
cytokine inducible SH2-containing protein
chr1_+_45015350 0.37 ENSDART00000143363
si:ch211-214c7.4
chr17_+_51675406 0.37 ENSDART00000157171
si:ch211-168d23.3
chr22_-_20899539 0.37 ENSDART00000100642
elongation factor RNA polymerase II
chr22_-_38271070 0.37 ENSDART00000165430
ENSDART00000059690
Hermansky-Pudlak syndrome 3
chr8_-_17132057 0.37 ENSDART00000143920
mitochondrial ribosomal protein S36
chr10_+_33439121 0.37 ENSDART00000063662
malate dehydrogenase 2, NAD (mitochondrial)
chr9_-_7676791 0.36 ENSDART00000136438
DnaJ (Hsp40) homolog, subfamily B, member 2
chr10_-_17753753 0.36

chr17_-_4160288 0.36 ENSDART00000153824
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr18_+_44656426 0.36 ENSDART00000059063
EH-domain containing 2b
chr17_+_44327269 0.35 ENSDART00000045882
adaptor-related protein complex 5, mu 1 subunit
chr6_+_59762717 0.34 ENSDART00000050457
zgc:65895
chr20_-_194135 0.34 ENSDART00000064546
si:ch211-241j12.3
chr11_-_37816180 0.34 ENSDART00000086516
kelch domain containing 8A
chr21_+_6091802 0.34 ENSDART00000147716
si:dkey-93m18.3
chr4_+_9010972 0.34 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr1_-_689420 0.34

chr6_+_41506446 0.33 ENSDART00000140108
cytokine inducible SH2-containing protein
chr7_+_28773716 0.33 ENSDART00000086871
glucose-fructose oxidoreductase domain containing 2
chr23_-_17543731 0.33 ENSDART00000002398
tripartite motif containing 101
chr5_-_3673698 0.33

chr23_+_30971404 0.33 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr21_+_1622040 0.33 ENSDART00000148540
ferrochelatase
chr16_+_5542562 0.33

chr9_-_7676688 0.33 ENSDART00000102706
DnaJ (Hsp40) homolog, subfamily B, member 2
chr11_-_36017410 0.33 ENSDART00000122531
nuclear transcription factor Y, alpha
chr9_-_296560 0.33 ENSDART00000160220
kinesin family member 5A, a
chr25_+_4414750 0.33 ENSDART00000129978
patatin-like phospholipase domain containing 2
chr10_-_44170848 0.32 ENSDART00000135240
acyl-CoA dehydrogenase, C-2 to C-3 short chain
KN150123v1_-_37214 0.32

chr5_+_36456679 0.32 ENSDART00000036760
tubulin polymerization-promoting protein family member 2
chr8_+_53173077 0.32 ENSDART00000131514
NAD kinase a
chr18_-_33832 0.31 ENSDART00000158957
ENSDART00000129125
phosphodiesterase 8A
chr3_+_14238188 0.31 ENSDART00000165452
ENSDART00000171726
transmembrane protein 56b
chr25_-_36713728 0.31 ENSDART00000103222
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_9010890 0.31 ENSDART00000058007
sorting and assembly machinery component 50 homolog, like
chr7_+_23636549 0.31 ENSDART00000045479
synaptotagmin IV
chr22_-_12601276 0.31 ENSDART00000143261
centrosomal protein 70
chr25_-_5921772 0.31 ENSDART00000075184
sorting nexin 1a
chr4_-_4603294 0.31 ENSDART00000130601
ENSDARG00000090401
chr24_-_10935904 0.30 ENSDART00000003195
charged multivesicular body protein 4C
chr11_-_42263721 0.30 ENSDART00000130573
ATPase, H+ transporting, lysosomal accessory protein 1-like a
chr25_+_7318825 0.30 ENSDART00000159748
catalase
chr18_+_24490621 0.30 ENSDART00000143108
ENSDARG00000091941
chr18_+_27095471 0.29 ENSDART00000125326
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr9_-_1983772 0.29 ENSDART00000082339
homeobox D12a
chr18_+_6417959 0.29 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr22_-_11817641 0.29 ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr23_+_14834670 0.29 ENSDART00000143675
si:rp71-79p20.2
KN150165v1_+_30233 0.29

chr23_-_17503329 0.29 ENSDART00000132024
pancreatic progenitor cell differentiation and proliferation factor b
chr2_+_23567197 0.29 ENSDART00000167068
kinesin-associated protein 3b
chr20_-_15205248 0.29 ENSDART00000034011
flavin containing monooxygenase 5
chr21_-_22085596 0.29 ENSDART00000101726
solute carrier family 35, member F2
chr14_+_4044357 0.28 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr7_+_28881845 0.28 ENSDART00000138065
transmembrane protein with metallophosphoesterase domain
chr19_+_47707575 0.28 ENSDART00000163591
ENSDART00000159860
ENSDART00000138909
ENSDART00000158588
ENSDART00000170847
thiopurine S-methyltransferase, tandem duplicate 2
chr20_+_1175551 0.28 ENSDART00000041192
LYR motif containing 2
chr16_+_5377008 0.28 ENSDART00000133972
plectin b
chr6_+_54070547 0.27 ENSDART00000110845
fragile histidine triad gene
chr2_-_56531858 0.27 ENSDART00000113589
glutathione peroxidase 4b
chr22_-_11817587 0.27 ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr9_+_28420902 0.27

chr10_-_41430693 0.27 ENSDART00000052971
ENSDART00000128156
RAB11 family interacting protein 1 (class I) b
chr7_-_10318801 0.27 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr4_-_4603205 0.27 ENSDART00000130601
ENSDARG00000090401
chr9_+_28420988 0.27

chr20_-_54591757 0.27 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr23_-_10810264 0.26 ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr10_-_625501 0.26 ENSDART00000041236
ENSDART00000144882
regulatory factor X, 3 (influences HLA class II expression)
chr10_+_37457234 0.26 ENSDART00000136554
A kinase (PRKA) anchor protein 1a
chr13_+_36638875 0.26 ENSDART00000111832
atlastin GTPase 1
chr25_-_25641897 0.26 ENSDART00000166308
calcium and integrin binding family member 2
chr11_-_6870810 0.26 ENSDART00000007204
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr4_-_18660286 0.26 ENSDART00000178638
peroxisome proliferator-activated receptor alpha a
chr15_-_43283562 0.26 ENSDART00000110352
adaptor-related protein complex 1, sigma 3 subunit, a
chr6_+_29702868 0.25 ENSDART00000114172
phosphodiesterase 6D, cGMP-specific, rod, delta
chr2_+_19588034 0.25 ENSDART00000163875
coiled-coil and C2 domain containing 1B
chr9_-_296499 0.25 ENSDART00000165228
kinesin family member 5A, a
chr25_+_22222388 0.25 ENSDART00000154376
cytochrome P450, family 11, subfamily A, polypeptide 1
chr14_+_26141096 0.25 ENSDART00000054183
G protein-coupled receptor 137
chr14_+_32923977 0.25 ENSDART00000075187
PDZ domain containing 11
chr12_-_33481348 0.25 ENSDART00000009794
ENSDART00000136617
tudor and KH domain containing
chr21_+_13063614 0.25

chr2_+_26002426 0.25 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr12_+_42281154 0.25 ENSDART00000167324
early B-cell factor 3a
chr21_-_43332911 0.25 ENSDART00000114955
sosondowah ankyrin repeat domain family member Aa
chr17_+_16421892 0.24 ENSDART00000136078
EF-hand calcium binding domain 11
chr10_+_37556367 0.24 ENSDART00000135642
musashi RNA-binding protein 2a
chr15_-_30935719 0.24 ENSDART00000050649
musashi RNA-binding protein 2b
chr15_-_19192933 0.24 ENSDART00000152428
Rho GTPase activating protein 32a
chr15_-_9616877 0.24 ENSDART00000168668
GRB2-associated binding protein 2
chr16_+_14135089 0.24

chr19_+_8225252 0.24 ENSDART00000147218
ephrin-A3a
chr7_-_6295302 0.24 ENSDART00000173199
si:ch1073-153i20.5
chr1_-_6403371 0.23

chr17_-_36988937 0.23 ENSDART00000145236
dihydropyrimidinase-like 5a
chr13_+_16148867 0.23 ENSDART00000142408
annexin A11a
chr25_-_13057808 0.23 ENSDART00000172571
sphingomyelin phosphodiesterase 3, neutral
chr13_-_31267133 0.23 ENSDART00000008287
phosphoglycerate mutase 1a
chr1_-_45972732 0.23 ENSDART00000134450
emopamil binding protein-like
chr1_+_45015381 0.23 ENSDART00000143363
si:ch211-214c7.4
chr25_+_4508802 0.23 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr4_-_4698425 0.22 ENSDART00000093005
ENSDARG00000063578
chr8_-_410190 0.22 ENSDART00000151155
tripartite motif containing 36
chr6_-_40660116 0.22 ENSDART00000154359
peptidylprolyl isomerase (cyclophilin)-like 1
chr23_-_10810190 0.22 ENSDART00000140745
eukaryotic translation initiation factor 4E family member 3
chr10_-_17753457 0.22 ENSDART00000147553
StAR-related lipid transfer (START) domain containing 7
chr15_+_28477741 0.22 ENSDART00000057257
phosphatidylinositol transfer protein, alpha a
chr5_-_11531015 0.22 ENSDART00000159896
GATS protein-like 3
chr7_+_10320888 0.21 ENSDART00000173125
zinc finger, AN1-type domain 6
chr3_+_17801981 0.21 ENSDART00000164663
ATP citrate lyase a
chr2_+_11245538 0.21 ENSDART00000138737
ENSDART00000081058
acyl-CoA thioesterase 11a
chr13_-_42547873 0.21 ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2
chr25_+_3381667 0.21 ENSDART00000157777
zgc:153293
chr6_+_22049537 0.21 ENSDART00000158263
si:dkey-10p5.10
chr16_-_52847642 0.21 ENSDART00000147236
antizyme inhibitor 1a
chr2_-_1677190 0.21 ENSDART00000024135
tubulin, beta 2A class IIa
chr5_+_37662896 0.21 ENSDART00000051231
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr3_-_36117170 0.21 ENSDART00000158701
ENSDART00000141106
G protein pathway suppressor 1
chr13_-_42548129 0.21 ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.3 1.0 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.3 0.9 GO:0006683 galactosylceramide catabolic process(GO:0006683) galactolipid catabolic process(GO:0019376)
0.3 1.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.3 0.3 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.2 1.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.6 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 0.7 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150) negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.2 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.7 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.7 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.1 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.1 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.4 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.3 GO:0010566 regulation of ketone biosynthetic process(GO:0010566) protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698)
0.1 0.2 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.4 GO:0032094 response to food(GO:0032094)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.5 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.2 GO:0046661 development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.0 0.2 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888) positive regulation of fatty acid metabolic process(GO:0045923)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 1.0 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 1.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 1.2 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.6 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.3 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 1.3 GO:0006954 inflammatory response(GO:0006954)
0.0 0.0 GO:0052805 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.4 GO:0043648 dicarboxylic acid metabolic process(GO:0043648)
0.0 0.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.9 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:1902743 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0 0.0 GO:0032355 response to estradiol(GO:0032355)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.4 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0001650 fibrillar center(GO:0001650)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.4 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004336 galactosylceramidase activity(GO:0004336)
0.2 1.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.7 GO:0004630 phospholipase D activity(GO:0004630)
0.2 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.6 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.6 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.9 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.3 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.1 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.7 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)