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Results for klf12b

Z-value: 3.27

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Transcription factors associated with klf12b

Gene Symbol Gene ID Gene Info
klf12b
ENSDARG00000032197 Kruppel-like factor 12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12bdr10_dc_chr9_+_30909382_309094270.947.7e-08Click!

Activity profile of klf12b motif

Sorted Z-values of klf12b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_43501747 10.45 ENSDART00000002279
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr13_-_39821399 9.37 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr20_+_17840364 9.19 ENSDART00000024627
cdh2
cadherin 2, type 1, N-cadherin (neuronal)
chr16_+_24057260 8.25 ENSDART00000132742
ENSDART00000145330
apoc1
apolipoprotein C-I
chr25_-_30845998 8.13 ENSDART00000027661
myod1
myogenic differentiation 1
chr13_+_13550656 7.72 ENSDART00000057825
cfd
complement factor D (adipsin)
chr22_-_4264838 7.51 ENSDART00000125302
fbn2b
fibrillin 2b
chr6_+_57744081 6.46 ENSDART00000169175
SNTA1
syntrophin alpha 1
chr22_-_26333957 6.35 ENSDART00000130493
capn2b
calpain 2, (m/II) large subunit b
chr7_+_44373815 6.26 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr2_-_20941256 6.17 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr13_-_11404389 6.14 ENSDART00000018155
adss
adenylosuccinate synthase
chr21_-_37509454 6.02 ENSDART00000175126
fgfr4
fibroblast growth factor receptor 4
chr22_+_12406830 5.77 ENSDART00000108609
rnd3a
Rho family GTPase 3a
chr20_-_19646761 5.69

KN150256v1_-_9467 5.44

chr5_-_66792947 5.42 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr20_+_23392782 5.42

chr16_+_24032160 5.37 ENSDART00000103190
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr6_+_19795100 5.35

chr2_-_29501573 5.31 ENSDART00000138073
cahz
carbonic anhydrase
chr5_+_51392394 5.19 ENSDART00000143276
setbp1
SET binding protein 1
chr17_-_49878964 5.19 ENSDART00000154728
col12a1a
collagen, type XII, alpha 1a
chr7_-_43501636 5.17 ENSDART00000002279
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_-_4079427 5.10 ENSDART00000170325
map7d1b
MAP7 domain containing 1b
chr22_-_2870591 5.08 ENSDART00000063533
aqp12
aquaporin 12
chr1_+_16683931 4.99 ENSDART00000103262
ENSDART00000145068
ENSDART00000169619
ENSDART00000010526
fat1a
FAT atypical cadherin 1a
chr3_+_15355472 4.87 ENSDART00000141714
nupr1
nuclear protein 1
chr1_+_26418707 4.86 ENSDART00000161169
bnc2
basonuclin 2
chr22_+_5697877 4.86 ENSDART00000063484
si:dkey-222f2.1
si:dkey-222f2.1
chr24_-_31772736 4.86

chr14_-_46219646 4.84 ENSDART00000110191
shisa3
shisa family member 3
chr23_-_9924987 4.77 ENSDART00000005015
prkcbp1l
protein kinase C binding protein 1, like
chr25_-_2485276 4.74 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr1_+_44137973 4.68

chr11_-_471166 4.67 ENSDART00000154888
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr7_-_69639922 4.66

chr14_-_20760787 4.60

chr14_+_20809272 4.58 ENSDART00000139865
aldob
aldolase b, fructose-bisphosphate
chr11_+_23695123 4.56 ENSDART00000000486
cntn2
contactin 2
chr2_+_19546837 4.54 ENSDART00000163137
elovl1a
ELOVL fatty acid elongase 1a
chr17_+_31346338 4.54 ENSDART00000062900
itpka
inositol-trisphosphate 3-kinase A
chr14_-_36523075 4.51 ENSDART00000109293
rnf130
ring finger protein 130
chr9_-_14533551 4.50 ENSDART00000056103
nrp2b
neuropilin 2b
chr17_+_15425559 4.48 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr16_-_7525980 4.41 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr17_-_30846176 4.36 ENSDART00000062811
yy1a
YY1 transcription factor a
chr5_-_23697487 4.28 ENSDART00000013309
sox19a
SRY (sex determining region Y)-box 19a
chr11_+_10925475 4.24 ENSDART00000064860
rbms1a
RNA binding motif, single stranded interacting protein 1a
chr22_+_37944019 4.22

chr1_-_44888989 4.21 ENSDART00000135089
atf7ip
activating transcription factor 7 interacting protein
chr20_-_22036656 4.19 ENSDART00000152290
daam1b
dishevelled associated activator of morphogenesis 1b
chr25_-_207828 4.17 ENSDART00000169152
srpk2
SRSF protein kinase 2
chr1_-_34921848 4.14 ENSDART00000142154
frem3
Fras1 related extracellular matrix 3
chr9_-_22140954 4.10 ENSDART00000146528
lmo7a
LIM domain 7a
chr9_-_31467299 4.05 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr13_-_36996246 4.02 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr8_-_17480730 4.02 ENSDART00000100667
skia
v-ski avian sarcoma viral oncogene homolog a
chr20_-_44598129 4.00 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr4_+_5733160 4.00 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr9_-_32942783 3.99 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr10_+_3728747 3.98

chr6_+_13613459 3.96 ENSDART00000104722
cdk5r2a
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr22_+_659157 3.92 ENSDART00000149712
gpr37l1a
G protein-coupled receptor 37 like 1a
chr18_-_15404998 3.89 ENSDART00000031752
rfx4
regulatory factor X, 4
chr4_-_6800721 3.88 ENSDART00000099467
ifrd1
interferon-related developmental regulator 1
chr3_-_36339966 3.85 ENSDART00000176547
ppl
periplakin
chr17_+_18097490 3.84 ENSDART00000144894
bcl11ba
B-cell CLL/lymphoma 11Ba (zinc finger protein)
chr25_+_4490129 3.81

chr16_+_17705704 3.78

chr24_+_7607915 3.75 ENSDART00000124409
cavin1b
caveolae associated protein 1b
chr19_-_7501777 3.74 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr16_-_39951493 3.73

chr18_+_20504980 3.71 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr19_+_15538967 3.71 ENSDART00000171403
lin28a
lin-28 homolog A (C. elegans)
chr18_+_9213713 3.69 ENSDART00000127469
ENSDART00000101192
sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr24_-_21844170 3.59 ENSDART00000032963
apoob
apolipoprotein O, b
chr23_-_24240728 3.55 ENSDART00000113598
arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr16_+_16941228 3.49 ENSDART00000142155
myh14
myosin, heavy chain 14, non-muscle
chr5_-_65103664 3.49 ENSDART00000130888
notch1b
notch 1b
chr4_+_21485280 3.48 ENSDART00000066896
syt1a
synaptotagmin Ia
chr8_+_20125687 3.48 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr2_-_30340646 3.47 ENSDART00000099078
jph1b
junctophilin 1b
chr16_+_21121428 3.44

chr20_-_22036622 3.42 ENSDART00000152290
daam1b
dishevelled associated activator of morphogenesis 1b
chr21_+_17731439 3.41 ENSDART00000124173
rxraa
retinoid X receptor, alpha a
chr14_-_30363703 3.41 ENSDART00000134098
efemp2a
EGF containing fibulin-like extracellular matrix protein 2a
chr6_-_39008833 3.40 ENSDART00000150885
vdrb
vitamin D receptor b
chr18_-_15405161 3.39 ENSDART00000031752
rfx4
regulatory factor X, 4
chr8_+_42992323 3.38 ENSDART00000048819
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr24_+_18804086 3.37 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr21_-_36338514 3.35 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr13_+_19191645 3.31 ENSDART00000058036
emx2
empty spiracles homeobox 2
chr9_-_7695437 3.29 ENSDART00000102715
tuba8l3
tubulin, alpha 8 like 3
chr7_-_29811734 3.26 ENSDART00000075600
tspan3b
tetraspanin 3b
chr1_+_16681778 3.26

chr2_-_10919978 3.25 ENSDART00000005944
rpl5a
ribosomal protein L5a
chr3_-_32190009 3.23

chr15_-_20088439 3.23 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr25_+_18467217 3.21 ENSDART00000170841
cav1
caveolin 1
chr6_-_39009073 3.21 ENSDART00000150885
vdrb
vitamin D receptor b
KN149817v1_+_2207 3.21

chr14_+_22889826 3.20 ENSDART00000170356
enox2
ecto-NOX disulfide-thiol exchanger 2
chr1_-_11474337 3.19 ENSDART00000149913
b4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr25_+_15551288 3.18 ENSDART00000137375
spon1b
spondin 1b
chr3_+_22412059 3.14

chr10_-_23939618 3.12

chr17_+_45834257 3.11 ENSDART00000035152
kif26ab
kinesin family member 26Ab
chr16_+_5470544 3.04

chr10_-_32614936 2.98 ENSDART00000143301
mogat2
monoacylglycerol O-acyltransferase 2
chr24_+_21200975 2.98 ENSDART00000126519
shisa2b
shisa family member 2b
chr7_+_40183905 2.97 ENSDART00000173916
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr6_+_24717985 2.94 ENSDART00000165609
barhl2
BarH-like homeobox 2
chr5_-_65103730 2.93 ENSDART00000169616
notch1b
notch 1b
chr23_-_23474703 2.91 ENSDART00000078936
her9
hairy-related 9
chr3_+_17760847 2.90 ENSDART00000080946
ttc25
tetratricopeptide repeat domain 25
chr13_-_31339870 2.88 ENSDART00000076574
rtn1a
reticulon 1a
chr23_-_7283514 2.87 ENSDART00000156369
CR589876.1
ENSDARG00000096997
chr20_-_22584941 2.84 ENSDART00000063601
gsx2
GS homeobox 2
chr24_-_16995194 2.82 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr8_-_15144533 2.81 ENSDART00000138855
bcar3
breast cancer anti-estrogen resistance 3
chr1_-_22160662 2.79 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr3_-_38550961 2.79 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr15_+_15479719 2.77 ENSDART00000127436
zgc:92630
zgc:92630
chr25_+_15551474 2.77 ENSDART00000137375
spon1b
spondin 1b
chr10_+_10393377 2.76 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr15_+_36197093 2.73 ENSDART00000156697
col4a3
collagen, type IV, alpha 3
chr21_-_36338704 2.71 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr15_-_36196994 2.71 ENSDART00000163061
col4a4
collagen, type IV, alpha 4
chr20_-_14158114 2.69 ENSDART00000009549
rhag
Rh-associated glycoprotein
chr10_-_5135388 2.69 ENSDART00000108587
sec31a
SEC31 homolog A, COPII coat complex component
chr20_+_15119519 2.69 ENSDART00000039345
myoc
myocilin
chr21_+_5887486 2.67 ENSDART00000048399
slc4a4b
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr23_-_3815492 2.64 ENSDART00000131536
hmga1a
high mobility group AT-hook 1a
chr6_-_34024063 2.64 ENSDART00000003701
tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr10_-_43924675 2.62 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr13_+_32013916 2.60 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr3_+_22962233 2.60 ENSDART00000142884
gngt2a
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr3_+_28822408 2.60 ENSDART00000133528
lgals2a
lectin, galactoside-binding, soluble, 2a
chr15_-_14616083 2.58 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr24_-_16994956 2.58 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr12_-_43917936 2.57 ENSDART00000159423
foxi1
forkhead box i1
chr8_-_15071283 2.56

chr18_-_25002972 2.55 ENSDART00000163449
chd2
chromodomain helicase DNA binding protein 2
chr9_-_2588401 2.54 ENSDART00000161018
sp9
sp9 transcription factor
chr2_+_16791661 2.52 ENSDART00000145107
agfg1b
ArfGAP with FG repeats 1b
chr13_-_33269297 2.52

chr13_+_21695882 2.50 ENSDART00000165150
zswim8
zinc finger, SWIM-type containing 8
chr7_-_46509291 2.50 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr15_-_10345337 2.48

chr18_-_46243753 2.46 ENSDART00000145999
prx
periaxin
chr1_-_40557436 2.45 ENSDART00000144424
rgs12b
regulator of G protein signaling 12b
chr19_+_17941678 2.45 ENSDART00000124597
nr1d2b
nuclear receptor subfamily 1, group D, member 2b
chr9_+_4188263 2.45 ENSDART00000164543
kalrna
kalirin RhoGEF kinase a
chr5_+_51392688 2.44 ENSDART00000143276
setbp1
SET binding protein 1
chr10_+_5693933 2.44 ENSDART00000159769
pam
peptidylglycine alpha-amidating monooxygenase
chr15_-_9443120 2.43 ENSDART00000177158
sacs
sacsin molecular chaperone
chr9_-_21257082 2.43 ENSDART00000124533
tbx15
T-box 15
chr4_+_22020246 2.42 ENSDART00000112035
ENSDART00000127664
myf5
myogenic factor 5
chr9_-_28464236 2.42 ENSDART00000146932
creb1b
cAMP responsive element binding protein 1b
chr3_+_32360862 2.40 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr7_-_58649991 2.37 ENSDART00000167076
mrc1a
mannose receptor, C type 1a
chr11_+_6079418 2.36 ENSDART00000158675
ushbp1
Usher syndrome 1C binding protein 1
chr16_-_38604326 2.34 ENSDART00000109124
rspo2
R-spondin 2
chr2_-_32468715 2.32

chr15_-_32738134 2.31 ENSDART00000164670
frem2b
Fras1 related extracellular matrix protein 2b
chr3_-_30554400 2.31 ENSDART00000151097
si:ch211-51c14.1
si:ch211-51c14.1
chr20_-_21773202 2.30 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr13_-_5808515 2.29 ENSDART00000165625
spred2b
sprouty-related, EVH1 domain containing 2b
chr5_-_20441931 2.26

chr8_-_6875110 2.25 ENSDART00000014915
asb6
ankyrin repeat and SOCS box containing 6
chr8_-_3253562 2.25 ENSDART00000035965
fut9b
fucosyltransferase 9b
chr8_-_3974357 2.22 ENSDART00000163754
ENSDART00000169474
mtmr3
myotubularin related protein 3
chr4_-_11595364 2.21 ENSDART00000002682
net1
neuroepithelial cell transforming 1
chr4_-_4825948 2.21 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr19_-_35828807 2.20

chr11_-_25017693 2.20

chr2_+_23038657 2.19 ENSDART00000089012
kif1ab
kinesin family member 1Ab
chr1_+_48708504 2.19 ENSDART00000008468
msx1b
muscle segment homeobox 1b
chr20_+_14979154 2.18 ENSDART00000118157
dre-mir-199-1
dre-mir-199-1
chr18_+_17594381 2.16 ENSDART00000010998
slc12a3
solute carrier family 12 (sodium/chloride transporter), member 3
chr24_+_37692365 2.14

chr13_-_18704185 2.14 ENSDART00000146795
lzts2a
leucine zipper, putative tumor suppressor 2a
chr16_+_17706003 2.12

chr5_+_22465722 2.10 ENSDART00000145477
ENSDART00000089992
hmgn7
high mobility group nucleosomal binding domain 7
chr12_+_3189489 2.09 ENSDART00000010569
g6pc3
glucose 6 phosphatase, catalytic, 3
chr20_+_38298893 2.08 ENSDART00000022694
ehd3
EH-domain containing 3
chr8_+_47352102 2.08

chr20_+_18310624 2.06 ENSDART00000111063
kctd1
potassium channel tetramerization domain containing 1
chr5_+_23585492 2.05 ENSDART00000135083
tp53
tumor protein p53
chr24_-_21324086 2.05

chr24_+_34227202 2.02 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr20_-_40217185 2.02

chr19_+_3925188 2.01

chr21_-_24552672 1.99

chr17_+_24428093 1.98 ENSDART00000131417
ugp2b
UDP-glucose pyrophosphorylase 2b
chr22_-_20360142 1.97 ENSDART00000089015
zbtb7a
zinc finger and BTB domain containing 7a
chr21_+_25757285 1.96 ENSDART00000101217
ENSDARG00000069505
ENSDARG00000069505
chr17_+_44666606 1.94 ENSDART00000155096
tmem63c
transmembrane protein 63C
chr21_+_25150600 1.94 ENSDART00000101147
si:dkey-183i3.5
si:dkey-183i3.5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
3.1 9.2 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
2.9 8.8 GO:0061323 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
2.7 8.2 GO:0032369 negative regulation of lipid transport(GO:0032369)
2.6 10.5 GO:0002074 extraocular skeletal muscle development(GO:0002074) pharyngeal muscle development(GO:0043282)
2.4 7.1 GO:0050810 regulation of steroid biosynthetic process(GO:0050810)
1.8 7.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.8 5.3 GO:0015670 carbon dioxide transport(GO:0015670)
1.3 2.7 GO:0019755 one-carbon compound transport(GO:0019755)
1.3 19.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.3 4.0 GO:0021742 abducens nucleus development(GO:0021742)
1.2 3.7 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
1.2 4.6 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
1.1 4.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
1.1 3.2 GO:0007624 ultradian rhythm(GO:0007624)
1.0 3.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
1.0 9.6 GO:0006956 complement activation(GO:0006956)
0.9 2.6 GO:0009957 epidermal cell fate specification(GO:0009957)
0.8 2.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.8 6.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.8 2.4 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.8 4.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 4.7 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.8 4.5 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.7 5.2 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.7 3.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 2.6 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.6 5.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.6 4.4 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.6 1.8 GO:0019835 cytolysis(GO:0019835)
0.6 2.3 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.5 1.6 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
0.5 1.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.5 1.5 GO:0006014 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.4 1.3 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.4 2.5 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.4 4.0 GO:0061337 cardiac conduction(GO:0061337)
0.4 1.9 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.4 2.6 GO:0090303 positive regulation of wound healing(GO:0090303)
0.4 3.3 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.4 4.2 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 5.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 3.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.3 5.2 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.3 2.4 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.3 1.2 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.3 1.8 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 4.2 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.3 7.4 GO:0060119 inner ear receptor cell development(GO:0060119)
0.3 3.8 GO:0097320 membrane tubulation(GO:0097320)
0.3 2.8 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3 2.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 0.8 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.3 2.1 GO:0051013 microtubule severing(GO:0051013)
0.3 5.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.3 2.0 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.2 1.2 GO:2000651 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 3.4 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.2 1.4 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784) regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 2.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.2 1.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 4.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.2 0.9 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.2 2.1 GO:0001964 startle response(GO:0001964)
0.2 1.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.2 2.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 2.3 GO:0033336 caudal fin development(GO:0033336)
0.2 4.9 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.2 4.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 4.3 GO:0030199 collagen fibril organization(GO:0030199)
0.2 2.7 GO:0015701 bicarbonate transport(GO:0015701)
0.2 6.9 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.2 3.6 GO:0042407 cristae formation(GO:0042407)
0.2 2.2 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.2 1.5 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.2 3.4 GO:0032526 response to retinoic acid(GO:0032526)
0.2 3.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 2.5 GO:1902667 regulation of axon guidance(GO:1902667)
0.2 3.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2 0.7 GO:1901998 toxin transport(GO:1901998)
0.2 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 1.5 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 0.8 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.2 0.9 GO:0016559 peroxisome fission(GO:0016559)
0.2 3.8 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 1.6 GO:0006959 humoral immune response(GO:0006959)
0.1 2.1 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 3.7 GO:0007416 synapse assembly(GO:0007416)
0.1 3.5 GO:0001843 neural tube closure(GO:0001843)
0.1 4.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.7 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.9 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.8 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.2 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.1 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 1.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.1 6.7 GO:0010842 retina layer formation(GO:0010842)
0.1 1.5 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.7 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 11.7 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.9 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 0.8 GO:0045117 azole transport(GO:0045117)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.1 3.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 2.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.4 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 2.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 7.7 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.1 4.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 1.9 GO:0003094 glomerular filtration(GO:0003094)
0.1 2.2 GO:0043049 otic placode formation(GO:0043049)
0.1 1.5 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.0 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.1 1.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 1.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 1.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.1 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 0.2 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 2.7 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.1 5.6 GO:0030155 regulation of cell adhesion(GO:0030155)
0.1 2.4 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.1 8.1 GO:0060026 convergent extension(GO:0060026)
0.1 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 3.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.9 GO:0009648 photoperiodism(GO:0009648)
0.0 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 2.9 GO:0051961 negative regulation of neurogenesis(GO:0050768) negative regulation of nervous system development(GO:0051961)
0.0 1.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 2.4 GO:0021782 glial cell development(GO:0021782)
0.0 0.8 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.5 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.3 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 5.4 GO:0006869 lipid transport(GO:0006869)
0.0 0.7 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 2.4 GO:0001708 cell fate specification(GO:0001708)
0.0 1.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.3 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0043489 RNA stabilization(GO:0043489)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 1.3 GO:0007254 JNK cascade(GO:0007254)
0.0 0.6 GO:0046460 neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.4 GO:0060840 artery development(GO:0060840)
0.0 3.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.3 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 3.5 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.8 GO:0021510 spinal cord development(GO:0021510)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 1.4 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 6.9 GO:0007420 brain development(GO:0007420)
0.0 0.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.9 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 1.8 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.4 GO:0070507 regulation of microtubule-based process(GO:0032886) regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 2.1 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.2 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.1 GO:0050767 regulation of neurogenesis(GO:0050767)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0030314 junctional membrane complex(GO:0030314)
1.0 4.0 GO:0042584 chromaffin granule membrane(GO:0042584)
0.9 8.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.8 9.2 GO:0014704 intercalated disc(GO:0014704)
0.6 1.8 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.5 12.9 GO:0016342 catenin complex(GO:0016342)
0.5 2.6 GO:0043034 costamere(GO:0043034)
0.5 2.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.4 1.9 GO:0016234 inclusion body(GO:0016234)
0.3 3.7 GO:0060170 ciliary membrane(GO:0060170)
0.3 9.8 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.3 3.1 GO:0030056 hemidesmosome(GO:0030056)
0.3 1.4 GO:0032420 stereocilium(GO:0032420)
0.3 3.6 GO:0061617 MICOS complex(GO:0061617)
0.3 1.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 2.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 2.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 13.4 GO:0005581 collagen trimer(GO:0005581)
0.2 2.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 8.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.8 GO:0001650 fibrillar center(GO:0001650)
0.1 18.8 GO:0031012 extracellular matrix(GO:0031012)
0.1 8.1 GO:0005882 intermediate filament(GO:0005882)
0.1 1.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.7 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 4.4 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 3.6 GO:0016459 myosin complex(GO:0016459)
0.1 7.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 36.0 GO:0005615 extracellular space(GO:0005615)
0.1 0.7 GO:0070938 contractile ring(GO:0070938)
0.1 15.8 GO:0043235 receptor complex(GO:0043235)
0.1 3.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.7 GO:0036126 sperm flagellum(GO:0036126)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 3.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 2.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 5.6 GO:0005874 microtubule(GO:0005874)
0.0 4.3 GO:0005938 cell cortex(GO:0005938)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.5 GO:0030425 dendrite(GO:0030425)
0.0 1.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.2 GO:0030424 axon(GO:0030424)
0.0 4.3 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0070644 vitamin D response element binding(GO:0070644)
1.5 4.5 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.3 5.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.2 8.1 GO:0070888 E-box binding(GO:0070888)
1.1 12.3 GO:0005504 fatty acid binding(GO:0005504)
0.7 2.8 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.7 3.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.7 3.3 GO:0008097 5S rRNA binding(GO:0008097)
0.6 2.6 GO:0016936 galactoside binding(GO:0016936)
0.6 3.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.6 2.4 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.5 1.6 GO:0070548 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) L-glutamine aminotransferase activity(GO:0070548)
0.5 3.7 GO:0043495 protein anchor(GO:0043495)
0.5 4.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 5.7 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.5 8.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 7.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 4.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 4.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.4 1.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.4 4.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.4 22.1 GO:0045296 cadherin binding(GO:0045296)
0.4 2.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.4 1.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 1.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 5.8 GO:0035497 cAMP response element binding(GO:0035497)
0.3 1.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 2.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 3.1 GO:0030506 ankyrin binding(GO:0030506)
0.3 3.7 GO:0038191 neuropilin binding(GO:0038191)
0.3 15.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 3.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 1.2 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 1.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 1.4 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.9 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.2 1.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 2.2 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.2 2.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 4.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 9.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 6.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 7.2 GO:0008013 beta-catenin binding(GO:0008013)
0.2 3.6 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.2 4.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 2.9 GO:0051020 GTPase binding(GO:0051020)
0.2 1.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.9 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.8 GO:0045118 azole transporter activity(GO:0045118) vitamin transmembrane transporter activity(GO:0090482) azole transmembrane transporter activity(GO:1901474)
0.1 5.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 4.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 4.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 1.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 9.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 3.9 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 7.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 16.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 6.7 GO:0003774 motor activity(GO:0003774)
0.1 0.3 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.1 1.2 GO:0005112 Notch binding(GO:0005112)
0.1 5.3 GO:0003678 DNA helicase activity(GO:0003678)
0.1 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 4.0 GO:0030276 clathrin binding(GO:0030276)
0.1 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.3 GO:0008201 heparin binding(GO:0008201)
0.0 2.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 3.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.9 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 7.0 GO:0019901 protein kinase binding(GO:0019901)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 59.6 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 9.9 GO:0038023 signaling receptor activity(GO:0038023)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.3 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 10.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.8 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.8 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 5.7 GO:0003779 actin binding(GO:0003779)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.9 GO:0003682 chromatin binding(GO:0003682)
0.0 1.3 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 2.3 GO:0005543 phospholipid binding(GO:0005543)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.6 6.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.6 4.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.4 19.6 PID FGF PATHWAY FGF signaling pathway
0.4 8.2 NABA COLLAGENS Genes encoding collagen proteins
0.3 8.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 11.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.3 PID AURORA A PATHWAY Aurora A signaling
0.1 1.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.8 8.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.9 22.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.6 4.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.6 12.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.5 10.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.4 6.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 2.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.3 3.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.3 0.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 4.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 1.5 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 1.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.7 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases