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Results for klf7a+klf7b

Z-value: 0.46

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Transcription factors associated with klf7a+klf7b

Gene Symbol Gene ID Gene Info
klf7b
ENSDARG00000043821 Kruppel-like factor 7b
klf7a
ENSDARG00000073857 Kruppel-like factor 7a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf7bdr10_dc_chr9_-_28588192_285881990.792.5e-04Click!
klf7adr10_dc_chr1_-_5796394_57964290.684.1e-03Click!

Activity profile of klf7a+klf7b motif

Sorted Z-values of klf7a+klf7b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of klf7a+klf7b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_7531709 1.33 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr12_-_20228689 1.09 ENSDART00000066384
hbbe2
hemoglobin beta embryonic-2
chr23_-_12079877 1.08 ENSDART00000147956
ENSDARG00000076364
ENSDARG00000076364
chr2_-_23516930 1.06 ENSDART00000165355
prrx1a
paired related homeobox 1a
chr11_-_41357639 0.98 ENSDART00000055709
her2
hairy-related 2
chr5_+_26195540 0.98 ENSDART00000145631
tcn2
transcobalamin II
chr25_+_35179025 0.95 ENSDART00000149768
kif21a
kinesin family member 21A
chr2_-_23517033 0.84 ENSDART00000041365
prrx1a
paired related homeobox 1a
chr19_+_31817286 0.82 ENSDART00000078459
tmem55a
transmembrane protein 55A
chr17_-_43725003 0.64

chr1_+_13386937 0.56 ENSDART00000021693
ank2a
ankyrin 2a, neuronal
chr2_-_42185811 0.49 ENSDART00000140788
gbp1
guanylate binding protein 1
chr2_-_42185736 0.48 ENSDART00000056460
gbp1
guanylate binding protein 1
chr15_-_7327976 0.44

chr20_+_18841440 0.41 ENSDART00000174532
fam167ab
family with sequence similarity 167, member Ab
chr20_+_13507202 0.38 ENSDART00000127350
enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr24_+_21876490 0.36 ENSDART00000081234
ropn1l
rhophilin associated tail protein 1-like
chr19_-_7531649 0.35 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr2_-_23516991 0.32 ENSDART00000165355
prrx1a
paired related homeobox 1a
chr5_+_32191063 0.32 ENSDART00000077189
ier5l
immediate early response 5-like
chr9_+_748282 0.30 ENSDART00000004498
insig2
insulin induced gene 2
chr1_-_43936717 0.29 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr1_-_10201135 0.26 ENSDART00000131744
dmd
dystrophin
chr21_+_8334453 0.22 ENSDART00000055336
dennd1a
DENN/MADD domain containing 1A
chr6_+_30681170 0.21 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr6_-_9798951 0.20

chr2_+_3062119 0.19 ENSDART00000110416
eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr4_-_28346021 0.19 ENSDART00000178149
celsr1a
cadherin EGF LAG seven-pass G-type receptor 1a
chr11_-_18073742 0.19

chr1_-_43936611 0.18 ENSDART00000170912
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr2_-_23516868 0.18 ENSDART00000165355
prrx1a
paired related homeobox 1a
chr23_-_19534700 0.18

chr7_-_37292692 0.17 ENSDART00000149052
nod2
nucleotide-binding oligomerization domain containing 2
chr10_-_41235132 0.17 ENSDART00000134851
aak1b
AP2 associated kinase 1b
chr16_-_7911453 0.16 ENSDART00000108653
tcaim
T-cell activation inhibitor, mitochondrial
chr19_-_30834919 0.15 ENSDART00000043554
ppp1r10
protein phosphatase 1, regulatory subunit 10
chr12_+_49071673 0.15

chr11_-_2524674 0.14 ENSDART00000114079
nab2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr23_+_1176124 0.13

chr15_-_7328008 0.11

chr19_+_1743359 0.10 ENSDART00000166744
dennd3a
DENN/MADD domain containing 3a
chr17_-_37848208 0.08 ENSDART00000025853
zfp36l1a
zinc finger protein 36, C3H type-like 1a
chr11_-_18073851 0.07

chr5_+_26195283 0.07 ENSDART00000053001
tcn2
transcobalamin II
chr20_+_20831085 0.04 ENSDART00000047662
ppp1r13bb
protein phosphatase 1, regulatory subunit 13Bb
chr25_+_21001071 0.04 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr3_-_28741820 0.03 ENSDART00000138840
eef2kmt
eukaryotic elongation factor 2 lysine methyltransferase
chr18_-_26912259 0.02 ENSDART00000147735
si:dkey-24l11.2
si:dkey-24l11.2
chr13_-_17333287 0.02 ENSDART00000145499
c13h10orf11
c13h10orf11 homolog (H. sapiens)
chr4_+_14728603 0.02 ENSDART00000131666
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr7_-_2230502 0.00 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0086019 atrial cardiac muscle cell action potential(GO:0086014) cell-cell signaling involved in cardiac conduction(GO:0086019) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) cell communication involved in cardiac conduction(GO:0086065) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
0.3 1.7 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881) membrane depolarization(GO:0051899) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.2 1.0 GO:0007405 neuroblast proliferation(GO:0007405)
0.1 1.1 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0055062 regulation of fat cell differentiation(GO:0045598) phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.1 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 1.0 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0031720 haptoglobin binding(GO:0031720)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation