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Results for lmx1al

Z-value: 0.78

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Transcription factors associated with lmx1al

Gene Symbol Gene ID Gene Info
ENSDARG00000077915 LIM homeobox transcription factor 1, alpha-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1aldr10_dc_chr3_+_52551672_525516770.283.0e-01Click!

Activity profile of lmx1al motif

Sorted Z-values of lmx1al motif

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1al

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_23516127 2.47 ENSDART00000004679
ictacalcin
chr20_-_22576513 1.96 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr9_-_30437160 1.87 ENSDART00000147241
ENSDARG00000092870
chr24_-_21778717 1.82 ENSDART00000131944
transgelin 3b
chr1_+_13779755 1.75

chr18_-_3056732 1.74 ENSDART00000162657
ribosomal protein S3
chr9_+_25966093 1.67 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr6_+_56157608 1.55 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr9_-_41608298 1.54

chr2_+_33343287 1.42 ENSDART00000056655
Kruppel-like factor 17
chr1_-_4757890 1.40 ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr7_+_19300351 1.39 ENSDART00000169060
si:ch211-212k18.5
chr8_-_22945616 1.38

chr25_-_14472107 1.34

chr13_+_27102308 1.34 ENSDART00000145901
Ras and Rab interactor 2
chr14_+_46419051 1.31 ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr24_-_14447773 1.29

chr3_-_35928594 1.29

chr11_+_34788205 1.26 ENSDART00000124800
family with sequence similarity 212, member Aa
chr19_+_7234029 1.22 ENSDART00000080348
bromodomain containing 2a
chr8_-_26623251 1.22 ENSDART00000159264
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr21_+_26684617 1.19 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr19_+_14197118 1.16 ENSDART00000166230
trophoblast glycoprotein a
chr13_+_27102377 1.15 ENSDART00000138043
Ras and Rab interactor 2
chr16_-_42990753 1.11 ENSDART00000149317
hemochromatosis type 2
chr9_-_12453581 1.11 ENSDART00000088199
zgc:162707
chr5_-_40707316 1.10 ENSDART00000161932
natriuretic peptide receptor 3
chr1_+_32935645 1.10 ENSDART00000170832
ADP-ribosylation factor-like 13b
chr6_-_18891908 1.09 ENSDART00000074327
insulin-like growth factor binding protein 2a
chr9_-_20562293 1.09 ENSDART00000113418
immunoglobulin superfamily, member 3
chr15_-_40391882 1.09

chr13_+_35213326 1.08 ENSDART00000019323
jagged 1b
chr20_-_475417 1.08 ENSDART00000032212
fyn-related Src family tyrosine kinase
chr9_-_48098629 1.08

chr24_-_6048914 1.06 ENSDART00000146830
ENSDART00000021981
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_-_6078015 1.03 ENSDART00000165715
ENSDARG00000098850
chr23_+_11350727 1.02

chr4_+_16896821 1.00 ENSDART00000017726
ethanolamine kinase 1
chr11_-_41241693 0.99 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr17_+_23278879 0.99 ENSDART00000153652
zgc:165461
chr8_+_21321765 0.97 ENSDART00000131691
aminolevulinate, delta-, synthase 2
chr7_+_6814828 0.97 ENSDART00000001649
actinin alpha 3b
chr14_-_17257773 0.96 ENSDART00000082667
fibroblast growth factor receptor-like 1a
chr16_-_29593569 0.96 ENSDART00000150028
one cut domain, family member, like
chr15_-_14616083 0.95 ENSDART00000171169
numb homolog (Drosophila)-like
chr6_-_43094573 0.94 ENSDART00000084389
leucine rich repeat neuronal 1
chr4_-_15442828 0.94 ENSDART00000157414
plexin A4
chr16_-_17439735 0.93 ENSDART00000144392
zyxin
chr6_+_13833991 0.91

chr3_+_25992836 0.90 ENSDART00000010477
heat shock cognate 70-kd protein, tandem duplicate 3
chr17_-_2513630 0.90 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr9_+_25966225 0.89 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr16_+_3090170 0.89 ENSDART00000110395
LIM domains containing 1a
chr10_-_11303185 0.89 ENSDART00000146727
polypyrimidine tract binding protein 3
chr2_+_49358871 0.89 ENSDART00000179089
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr18_-_43890514 0.88 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr20_-_9107294 0.87 ENSDART00000140792
OMA1 zinc metallopeptidase
chr19_+_31046291 0.87 ENSDART00000052124
family with sequence similarity 49, member A-like
chr1_-_40536800 0.86 ENSDART00000134739
regulator of G protein signaling 12b
chr6_+_23787804 0.85 ENSDART00000163188
zinc finger protein 648
chr16_+_24046472 0.84

chr2_-_7375138 0.82 ENSDART00000146434
zgc:153115
chr7_+_20251345 0.80 ENSDART00000157699
si:dkey-19b23.12
chr20_+_51385187 0.79

chr4_+_3970874 0.79 ENSDART00000049194
G protein-coupled receptor 37b
chr5_-_40894631 0.78 ENSDART00000121840
eukaryotic translation elongation factor 2, like 2
chr15_-_4537178 0.78 ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr3_-_60929921 0.77 ENSDART00000055064
parvalbumin 8
chr23_-_45927723 0.76

chr17_+_30352361 0.75 ENSDART00000076611
growth regulation by estrogen in breast cancer 1
chr6_-_43273456 0.75

chr17_-_29102320 0.74 ENSDART00000104204
forkhead box G1a
chr16_+_13928844 0.74 ENSDART00000090191
folliculin
chr12_+_24221087 0.72 ENSDART00000088178
neurexin 1a
chr18_-_19467100 0.72 ENSDART00000060363
ribosomal protein L4
chr24_+_21395671 0.72 ENSDART00000091529
WAS protein family, member 3b
chr17_-_26849495 0.72 ENSDART00000153590
si:dkey-221l4.10
chr16_+_23172295 0.71 ENSDART00000167518
ENSDART00000161087
ephrin-A3b
chr6_-_23193752 0.71 ENSDART00000159749
ubiquitin specific peptidase 43a
chr6_-_54816183 0.70 ENSDART00000148462
troponin I type 1b (skeletal, slow)
chr20_-_37587804 0.69 ENSDART00000166106
si:ch211-202p1.5
chr22_+_16509286 0.69 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr20_-_21031504 0.67 ENSDART00000152726
BTB (POZ) domain containing 6b
chr14_+_34151963 0.67 ENSDART00000144301
wingless-type MMTV integration site family, member 8a
chr2_+_21267793 0.66 ENSDART00000099913
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr17_+_15425559 0.66 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr21_-_20674965 0.66 ENSDART00000065649
ENSDARG00000044676
chr3_+_17387551 0.66 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr2_+_3370130 0.64 ENSDART00000098391
wingless-type MMTV integration site family, member 9A
chr20_+_29307039 0.64 ENSDART00000152949
katanin p80 subunit B-like 1
chr3_-_56474209 0.64 ENSDART00000156398
si:ch211-189a21.1
chr20_+_29307142 0.61 ENSDART00000153016
katanin p80 subunit B-like 1
chr16_+_46145286 0.61 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr5_+_18826505 0.61

chr3_-_39554155 0.61 ENSDART00000015393
B9 protein domain 1
chr2_+_50873893 0.60

chr14_-_1342450 0.58 ENSDART00000060417
centrin 4
chr1_-_25600988 0.58 ENSDART00000160381
CXXC finger 4
chr5_+_18827478 0.58 ENSDART00000089078
acetyl-CoA carboxylase beta
chr1_-_15972040 0.57 ENSDART00000040434
N-acylsphingosine amidohydrolase (acid ceramidase) 1b
chr22_-_7371498 0.57

chr25_+_14411153 0.56 ENSDART00000015681
developing brain homeobox 1b
chr3_-_60930025 0.56 ENSDART00000055064
parvalbumin 8
chr24_+_35899507 0.56 ENSDART00000122408
si:dkeyp-7a3.1
chr23_+_31986806 0.56 ENSDART00000136910
armadillo repeat containing 1, like
chr14_+_21816442 0.56 ENSDART00000109759
thioredoxin-related transmembrane protein 2a
chr6_+_28215039 0.54 ENSDART00000104394
smx5
chr8_-_19166630 0.53

chr2_-_49114158 0.53

chr1_-_40208544 0.52 ENSDART00000027463
H6 family homeobox 4
chr7_-_27877036 0.52 ENSDART00000044208
LIM domain only 1
chr25_+_4918339 0.52 ENSDART00000153980
parvin, beta
chr13_+_28617462 0.52 ENSDART00000101633
prominin 2
chr25_+_24193604 0.52 ENSDART00000083407
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr14_-_6901415 0.51 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr15_-_23441268 0.51 ENSDART00000078570
C1q and TNF related 5
chr10_+_11303321 0.50 ENSDART00000155333
hydroxysteroid dehydrogenase like 2
chr16_+_51319421 0.50

chr10_+_11809550 0.50 ENSDART00000092047
peptidylprolyl isomerase domain and WD repeat containing 1
chr6_-_43094926 0.50 ENSDART00000084389
leucine rich repeat neuronal 1
chr21_+_28921734 0.50 ENSDART00000166575
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_-_28739099 0.49 ENSDART00000135513
regulator of G protein signaling 6
chr2_-_57244462 0.49 ENSDART00000149235
transcription factor 3a
chr22_+_1274718 0.48 ENSDART00000159296
si:ch73-138e16.4
chr9_-_19154264 0.48 ENSDART00000081878
POU class 1 homeobox 1
chr16_+_43236190 0.48 ENSDART00000065643
DBF4 zinc finger
chr20_-_29028920 0.48 ENSDART00000153082
sushi domain containing 6
chr7_+_7463292 0.48 ENSDART00000091099
INO80 complex subunit B
chr7_+_24762755 0.47 ENSDART00000170873
sb:cb1058
chr1_-_50215233 0.47 ENSDART00000137648
si:dkeyp-123h10.2
chr24_-_24306469 0.46 ENSDART00000154149
ENSDARG00000097984
chr16_+_13993746 0.46 ENSDART00000101304
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr8_+_6533379 0.46 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr17_+_10437343 0.46 ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr21_-_44707326 0.46 ENSDART00000013814
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr22_-_12130441 0.45 ENSDART00000146785
transmembrane protein 163b
chr7_-_6309265 0.45 ENSDART00000172825
Histone H3.2
chr11_-_38282978 0.44

chr22_-_12905648 0.43 ENSDART00000157820
major facilitator superfamily domain containing 6a
chr20_-_3970778 0.42 ENSDART00000178724
ENSDART00000178565
tripartite motif containing 67
chr2_-_36058327 0.42 ENSDART00000003550
nicotinamide nucleotide adenylyltransferase 2
chr1_-_40208469 0.40 ENSDART00000027463
H6 family homeobox 4
chr5_+_35815450 0.40 ENSDART00000084464
family with sequence similarity 155, member B
chr24_+_9272045 0.40 ENSDART00000132724
si:ch211-285f17.1
chr10_-_32550379 0.39 ENSDART00000028161
UV radiation resistance associated gene
chr22_+_18228143 0.39 ENSDART00000141535
ENSDARG00000095557
chr7_-_26331734 0.38

chr22_-_13018196 0.38 ENSDART00000028787
aryl hydrocarbon receptor 1b
chr3_-_19913881 0.38 ENSDART00000126915
upstream binding transcription factor, RNA polymerase I
chr15_+_32963784 0.37 ENSDART00000167739
doublecortin-like kinase 1b
chr15_+_32963516 0.37 ENSDART00000167739
doublecortin-like kinase 1b
chr17_-_49355712 0.36 ENSDART00000004424
zinc finger protein 292a
chr5_-_40894693 0.36 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr20_-_48677794 0.36 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr19_-_42821964 0.36 ENSDART00000087002
pleckstrin homology domain containing, family O member 1a
chr8_-_18502159 0.35 ENSDART00000148802
ENSDART00000149081
ENSDART00000148962
nexilin (F actin binding protein)
chr9_-_43736549 0.35 ENSDART00000140526
zinc finger protein 385B
chr6_+_33896684 0.35 ENSDART00000165710
GC-rich promoter binding protein 1-like 1
chr9_+_4708975 0.35 ENSDART00000081326
PRP40 pre-mRNA processing factor 40 homolog A
chr11_+_36983626 0.35 ENSDART00000170209
interleukin 17 receptor C
chr22_+_38084309 0.34 ENSDART00000012212
COMM domain containing 2
chr5_+_19153421 0.34

chr3_+_27667194 0.33 ENSDART00000075100
calcium regulated heat stable protein 1
chr16_+_13928376 0.33 ENSDART00000163251
folliculin
chr11_+_18710724 0.32 ENSDART00000176141
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr8_-_11512545 0.32 ENSDART00000133932
si:ch211-248e11.2
chr23_+_36016450 0.32 ENSDART00000103035
homeobox C6a
chr19_-_10324632 0.31 ENSDART00000148073
shisa family member 7
chr6_-_57542101 0.31 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr8_+_21974863 0.31

chr20_-_475321 0.30 ENSDART00000032212
fyn-related Src family tyrosine kinase
chr9_+_36316158 0.29 ENSDART00000176763
low density lipoprotein receptor-related protein 1Bb
chr7_+_9726412 0.29 ENSDART00000173155
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr24_+_14095643 0.29 ENSDART00000124740
nuclear receptor coactivator 2
chr7_+_28896401 0.29 ENSDART00000076345
solute carrier family 38, member 8b
chr1_+_53384116 0.29 ENSDART00000149760
TRIO and F-actin binding protein a
chr12_+_18559530 0.28 ENSDART00000152948
regulator of G protein signaling 9b
chr20_-_23526954 0.28 ENSDART00000004625
zygote arrest 1
chr5_-_67233396 0.28 ENSDART00000051833
ENSDART00000124890
GS homeobox 1
chr24_+_16402613 0.28 ENSDART00000164319
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr20_-_46458839 0.28 ENSDART00000153087
Bcl2 modifying factor 2
chr12_-_34621359 0.27

chr7_+_9628564 0.27 ENSDART00000172813
ENSDART00000128376
lines homolog 1
chr11_-_6051096 0.27 ENSDART00000147761
vessel-specific 1
chr13_-_40027211 0.27

chr6_+_23611854 0.27 ENSDART00000167795
phosphoinositide-3-kinase, regulatory subunit 6a
chr11_-_6442836 0.26 ENSDART00000004483
zgc:162969
chr8_+_25015325 0.26 ENSDART00000140617
neugrin, neurite outgrowth associated
chr6_+_40924749 0.26 ENSDART00000133599
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_-_12706441 0.25 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr23_-_46268313 0.25 ENSDART00000170417
ENSDART00000168352
ENSDARG00000098990
chr19_-_13946434 0.25 ENSDART00000166895
connective tissue growth factor b
chr21_-_40653250 0.25 ENSDART00000162623
aristaless related homeobox b
chr19_-_11188322 0.25 ENSDART00000059102
Rho guanine nucleotide exchange factor (GEF) 1a
chr13_+_4096622 0.25 ENSDART00000058242
ENSDART00000143456
male-enhanced antigen 1
chr10_-_26782374 0.24 ENSDART00000162710
fibroblast growth factor 13b
chr10_+_39211384 0.24

chr21_+_26684728 0.24 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr22_-_2828572 0.24

chr4_+_11385828 0.23

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.4 1.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.4 1.4 GO:0048785 hatching gland development(GO:0048785)
0.3 0.7 GO:0030431 sleep(GO:0030431)
0.3 1.1 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.2 0.7 GO:0050886 phasic smooth muscle contraction(GO:0014821) vascular smooth muscle contraction(GO:0014829) endocrine process(GO:0050886)
0.2 0.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 2.0 GO:0003315 heart rudiment formation(GO:0003315)
0.2 1.4 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 1.2 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 0.6 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 1.4 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.2 0.7 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.7 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698) inflammatory response to wounding(GO:0090594)
0.1 0.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.1 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 0.9 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.9 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 1.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.6 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.6 GO:0097264 self proteolysis(GO:0097264)
0.1 1.1 GO:1904263 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) positive regulation of TORC1 signaling(GO:1904263)
0.1 0.3 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.7 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.0 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.5 GO:0033262 positive regulation of nuclear cell cycle DNA replication(GO:0010571) regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 0.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 0.7 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.9 GO:0042026 protein refolding(GO:0042026)
0.1 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.9 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 1.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.7 GO:0031641 regulation of myelination(GO:0031641)
0.1 1.0 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.8 GO:0043584 nose development(GO:0043584)
0.1 0.2 GO:2000623 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 1.1 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.1 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 2.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.4 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.8 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.9 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0099590 postsynaptic neurotransmitter receptor internalization(GO:0098884) neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.8 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033270 paranode region of axon(GO:0033270)
0.2 0.5 GO:0071914 prominosome(GO:0071914)
0.2 0.7 GO:0097189 apoptotic body(GO:0097189)
0.1 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:0031431 Dbf4-dependent protein kinase complex(GO:0031431)
0.1 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0005814 centriole(GO:0005814)
0.0 0.9 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.0 GO:0005929 cilium(GO:0005929)
0.0 0.7 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.0 0.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.5 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.6 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 1.1 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.9 GO:0019838 growth factor binding(GO:0019838)
0.1 0.5 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.1 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.6 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 2.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 2.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions