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Results for lmx1ba+lmx1bb

Z-value: 0.49

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Transcription factors associated with lmx1ba+lmx1bb

Gene Symbol Gene ID Gene Info
lmx1bb
ENSDARG00000068365 LIM homeobox transcription factor 1, beta b
lmx1ba
ENSDARG00000104815 LIM homeobox transcription factor 1, beta a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1bbdr10_dc_chr8_-_33372638_33372708-0.263.2e-01Click!

Activity profile of lmx1ba+lmx1bb motif

Sorted Z-values of lmx1ba+lmx1bb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1ba+lmx1bb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_34788205 1.27 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr2_+_33343287 0.89 ENSDART00000056655
klf17
Kruppel-like factor 17
chr14_+_23420053 0.72 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr16_+_24046472 0.58

chr14_+_23419894 0.53 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr23_-_31986679 0.51 ENSDART00000085054
mtfr2
mitochondrial fission regulator 2
chr23_-_31986571 0.46 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr7_+_19300351 0.43 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr2_+_10192670 0.42 ENSDART00000011906
slc35a3b
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr14_+_23419864 0.40 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr18_+_19467527 0.39 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr23_-_31986482 0.39 ENSDART00000135526
mtfr2
mitochondrial fission regulator 2
chr8_-_44247277 0.38

chr8_-_23591082 0.36 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr21_+_26684617 0.34 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr8_+_45326435 0.33 ENSDART00000134161
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_+_6925975 0.33

chr20_+_46588401 0.32 ENSDART00000060695
zc3h14
zinc finger CCCH-type containing 14
KN150200v1_+_7782 0.32

chr23_-_35691369 0.31 ENSDART00000142369
mfsd5
major facilitator superfamily domain containing 5
chr17_+_16082472 0.29 ENSDART00000133154
znf395a
zinc finger protein 395a
chr6_+_40925259 0.29 ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr22_-_2828572 0.28

chr14_+_34150130 0.28 ENSDART00000132193
ENSDART00000141058
wnt8a
BX927327.1
wingless-type MMTV integration site family, member 8a
ENSDARG00000105311
chr20_-_34126039 0.27 ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr1_+_25750825 0.27 ENSDART00000046376
g3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr3_-_13771322 0.25 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
si:dkey-61n16.5
chr8_+_28362546 0.25 ENSDART00000062682
adipor1b
adiponectin receptor 1b
chr19_+_770488 0.24 ENSDART00000062518
gstr
glutathione S-transferase rho
chr5_-_56539892 0.24

chr8_+_45326523 0.24 ENSDART00000145011
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr5_-_18459312 0.24 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr11_+_34909393 0.23 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr1_+_21244242 0.22 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr15_-_16241500 0.22 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr11_-_34258956 0.22 ENSDART00000114004
pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr7_-_26332194 0.21 ENSDART00000099003
plscr3b
phospholipid scramblase 3b
chr6_-_8156520 0.21 ENSDART00000081561
ilf3a
interleukin enhancer binding factor 3a
chr6_+_40924749 0.21 ENSDART00000133599
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr19_+_31297635 0.21 ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr8_-_23591293 0.21 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr10_-_32550351 0.20 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr19_+_42863138 0.20 ENSDART00000076938
pogza
pogo transposable element derived with ZNF domain a
chr16_-_29452509 0.20 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr5_-_13890202 0.19 ENSDART00000026120
ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr7_-_15008685 0.19 ENSDART00000173048
ENSDARG00000023868
ENSDARG00000023868
chr20_-_33272014 0.19 ENSDART00000178752
ENSDART00000047834
nbas
neuroblastoma amplified sequence
chr11_-_17620732 0.19 ENSDART00000154627
eogt
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr15_-_36490729 0.17

chr7_-_15008648 0.17 ENSDART00000173048
ENSDARG00000023868
ENSDARG00000023868
chr21_-_27584637 0.16

chr10_-_8238422 0.16 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr13_+_27102308 0.16 ENSDART00000145901
rin2
Ras and Rab interactor 2
chr9_-_52950815 0.16 ENSDART00000161667
smarcal1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr21_+_26684728 0.15 ENSDART00000053797
slc3a2b
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr8_-_5834829 0.15 ENSDART00000179217
ENSDARG00000106522
ENSDARG00000106522
chr7_-_26332236 0.14 ENSDART00000099003
plscr3b
phospholipid scramblase 3b
chr21_-_44707326 0.14 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr3_-_36080647 0.14 ENSDART00000025326
csnk1da
casein kinase 1, delta a
chr10_-_43070198 0.13 ENSDART00000099270
CU326366.2
ENSDARG00000068593
chr23_+_26300882 0.13

chr14_-_21717949 0.13 ENSDART00000137795
ssrp1a
structure specific recognition protein 1a
chr11_-_6442836 0.13 ENSDART00000004483
zgc:162969
zgc:162969
chr16_-_29451902 0.13

chr16_+_19728218 0.12

chr14_+_20045365 0.12 ENSDART00000167637
aff2
AF4/FMR2 family, member 2
chr10_+_17755665 0.12 ENSDART00000170453
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr8_+_30103357 0.12 ENSDART00000133717
fancc
Fanconi anemia, complementation group C
chr15_-_23587330 0.11 ENSDART00000167246
hmbsb
hydroxymethylbilane synthase, b
chr15_-_16241412 0.11 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr3_-_16569378 0.11 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr21_-_11877044 0.11 ENSDART00000145194
nop56
NOP56 ribonucleoprotein homolog
chr5_+_65754237 0.11 ENSDART00000170757
kntc1
kinetochore associated 1
chr7_+_71757218 0.11 ENSDART00000012918
psmd9
proteasome 26S subunit, non-ATPase 9
chr10_-_15382145 0.11 ENSDART00000133919
pum3
pumilio RNA-binding family member 3
chr13_-_50032548 0.11 ENSDART00000038120
cacul1
CDK2 associated cullin domain 1
chr5_-_68848113 0.10 ENSDART00000097249
aldh2.2
aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2
chr7_+_8492338 0.10

chr15_-_40391882 0.09

chr23_-_29627060 0.09 ENSDART00000166554
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr13_+_27102377 0.09 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr5_-_50346132 0.09 ENSDART00000097460
hmgcra
3-hydroxy-3-methylglutaryl-CoA reductase a
chr7_+_7463292 0.09 ENSDART00000091099
ino80b
INO80 complex subunit B
chr16_-_21238288 0.08 ENSDART00000139737
cbx3b
chromobox homolog 3b
chr9_-_12623451 0.08 ENSDART00000142024
tra2b
transformer 2 beta homolog
chr23_-_25853364 0.08 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr11_-_34909095 0.08 ENSDART00000017393
traip
TRAF-interacting protein
chr13_-_36015558 0.08 ENSDART00000133072
med6
mediator complex subunit 6
chr18_-_43890836 0.08 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr18_-_40718244 0.08 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr8_+_25015374 0.08 ENSDART00000140617
ngrn
neugrin, neurite outgrowth associated
chr17_-_2513630 0.08 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr1_+_43471754 0.07 ENSDART00000166324
ctnnd1
catenin (cadherin-associated protein), delta 1
chr23_-_25853220 0.07 ENSDART00000110670
ENSDARG00000078574
ENSDARG00000078574
chr15_-_5912105 0.07

chr11_+_17849528 0.07 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr14_-_6831373 0.07 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr14_-_6831308 0.07 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr1_+_43471683 0.07 ENSDART00000166324
ctnnd1
catenin (cadherin-associated protein), delta 1
chr11_+_17849608 0.06 ENSDART00000020283
rpusd4
RNA pseudouridylate synthase domain containing 4
chr5_+_20640468 0.06 ENSDART00000028087
cds2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr22_+_1153361 0.06 ENSDART00000159761
irf6
interferon regulatory factor 6
chr12_-_45496246 0.06 ENSDART00000176229
ENSDART00000175457
FO818685.1
ENSDARG00000107895
chr24_+_8702288 0.05 ENSDART00000114810
sycp2l
synaptonemal complex protein 2-like
chr12_+_22497249 0.05 ENSDART00000178120
CR848021.1
ENSDARG00000107088
chr18_+_20571400 0.05 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr3_+_17387551 0.05 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr24_-_16922912 0.05 ENSDART00000111237
armc3
armadillo repeat containing 3
chr24_+_28304003 0.05 ENSDART00000018095
sh3glb1a
SH3-domain GRB2-like endophilin B1a
chr11_-_30364626 0.05 ENSDART00000089803
ENSDART00000046800
ENSDART00000172244
slc8a1a
solute carrier family 8 (sodium/calcium exchanger), member 1a
chr17_+_23278879 0.05 ENSDART00000153652
zgc:165461
zgc:165461
chr20_+_47588954 0.05 ENSDART00000021341
kif3ca
kinesin family member 3Ca
chr11_-_37730181 0.05 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr3_+_22312446 0.04 ENSDART00000156450
wnk4b
WNK lysine deficient protein kinase 4b
chr12_-_26062065 0.04 ENSDART00000076051
opn4b
opsin 4b
chr6_-_32001100 0.04 ENSDART00000132280
ror1
receptor tyrosine kinase-like orphan receptor 1
chr22_-_17627831 0.04 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr16_+_25202272 0.04 ENSDART00000163244
si:ch211-261d7.6
si:ch211-261d7.6
chr22_+_1153570 0.04 ENSDART00000157442
irf6
interferon regulatory factor 6
chr23_+_45486958 0.03 ENSDART00000111126
psip1b
PC4 and SFRS1 interacting protein 1b
chr20_-_23527004 0.03 ENSDART00000004625
zar1
zygote arrest 1
chr16_-_31494275 0.03 ENSDART00000056551
csnk2a1
casein kinase 2, alpha 1 polypeptide
chr17_+_10437343 0.03 ENSDART00000167188
mapkbp1
mitogen-activated protein kinase binding protein 1
chr10_-_34971926 0.03 ENSDART00000141201
ccna1
cyclin A1
chr13_+_33173790 0.03 ENSDART00000145295
dcdc2b
doublecortin domain containing 2B
chr14_-_6831278 0.03 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr4_+_13587809 0.03 ENSDART00000138201
tnpo3
transportin 3
chr6_+_13833991 0.03

chr3_+_48811662 0.03 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr10_+_39211384 0.03

chr14_-_33605295 0.02 ENSDART00000168546
zdhhc24
zinc finger, DHHC-type containing 24
chr4_+_9668755 0.02 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr1_+_35253821 0.02 ENSDART00000179634
zgc:152968
zgc:152968
chr24_-_14447773 0.02

chr15_-_5911817 0.02

chr19_-_42759951 0.02

chr13_-_40027211 0.02

chr14_-_3836967 0.02 ENSDART00000055817
ENSDARG00000038270
ENSDARG00000038270
chr5_-_28693064 0.02

chr3_-_26112995 0.02 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr1_-_25750237 0.02 ENSDART00000125690
ints12
integrator complex subunit 12
chr22_-_17627900 0.02 ENSDART00000138483
si:ch73-243b8.4
si:ch73-243b8.4
chr7_-_26331734 0.02

chr21_-_40653250 0.02 ENSDART00000162623
arxb
aristaless related homeobox b
chr19_-_1921502 0.02 ENSDART00000004585
clptm1l
CLPTM1-like
chr24_-_35673629 0.02 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr20_-_9107294 0.01 ENSDART00000140792
OMA1
OMA1 zinc metallopeptidase
chr17_+_9152727 0.01

chr16_-_42105636 0.01 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr25_-_3742327 0.01 ENSDART00000075663
cracr2b
calcium release activated channel regulator 2B
chr25_-_19388381 0.01 ENSDART00000154986
zgc:193812
zgc:193812
chr10_-_25448712 0.01 ENSDART00000140023
grik1a
glutamate receptor, ionotropic, kainate 1a
chr9_+_36316158 0.01 ENSDART00000176763
lrp1bb
low density lipoprotein receptor-related protein 1Bb
chr8_+_1834454 0.00 ENSDART00000056208
snap29
synaptosomal-associated protein 29
chr3_-_29932835 0.00

chr8_-_11512545 0.00 ENSDART00000133932
si:ch211-248e11.2
si:ch211-248e11.2
chr13_-_37340209 0.00

chr7_+_23752492 0.00 ENSDART00000141165
tinf2
TERF1 (TRF1)-interacting nuclear factor 2
chr17_-_31562669 0.00 ENSDART00000110167
rpap1
RNA polymerase II associated protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0048785 hatching gland development(GO:0048785)
0.2 0.6 GO:0089709 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.4 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.1 0.3 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.3 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.2 GO:2000622 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 1.4 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.1 GO:0001659 temperature homeostasis(GO:0001659)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 1.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.4 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0035493 SNARE complex assembly(GO:0035493)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097189 apoptotic body(GO:0097189)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0050699 WW domain binding(GO:0050699)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0008665 tRNA 2'-phosphotransferase activity(GO:0000215) 2'-phosphotransferase activity(GO:0008665)
0.0 0.4 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling