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Results for mafa+mafbb

Z-value: 1.10

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Transcription factors associated with mafa+mafbb

Gene Symbol Gene ID Gene Info
mafa
ENSDARG00000015890 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
mafbb
ENSDARG00000070542 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafadr10_dc_chr18_+_29424354_294244060.886.8e-06Click!
mafbbdr10_dc_chr11_-_25146564_251465980.683.8e-03Click!

Activity profile of mafa+mafbb motif

Sorted Z-values of mafa+mafbb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mafa+mafbb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr25_+_30699938 5.35 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr6_-_13654186 3.77 ENSDART00000150102
ENSDART00000041269
cryba2a
crystallin, beta A2a
chr24_-_12794564 3.65 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr5_-_66792947 3.21 ENSDART00000147009
si:dkey-251i10.2
si:dkey-251i10.2
chr16_+_46327528 3.18 ENSDART00000040769
nr2f5
nuclear receptor subfamily 2, group F, member 5
chr3_-_17881044 3.17 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr15_-_29454583 3.16 ENSDART00000145976
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr13_+_2774422 3.10 ENSDART00000162362
wu:fj16a03
wu:fj16a03
chr2_-_24898678 2.86 ENSDART00000145145
cnn2
calponin 2
chr8_-_41194452 2.85 ENSDART00000165949
fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr11_-_5868257 2.63 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr16_+_33702010 2.62 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr14_-_45883839 2.57

chr10_+_10843384 2.52 ENSDART00000130283
ambp
alpha-1-microglobulin/bikunin precursor
chr13_-_33574216 2.49 ENSDART00000065435
cst3
cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr20_-_14158114 2.49 ENSDART00000009549
rhag
Rh-associated glycoprotein
chr20_-_47123598 2.45 ENSDART00000100320
dnmt3aa
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr22_-_6977038 2.37 ENSDART00000133143
ENSDART00000146813
gpd1b
glycerol-3-phosphate dehydrogenase 1b
chr20_-_29517770 2.34 ENSDART00000147464
ryr3
ryanodine receptor 3
chr5_-_30015572 2.34 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr1_-_29706856 2.29 ENSDART00000174868
igf2bp2b
insulin-like growth factor 2 mRNA binding protein 2b
chr21_+_43204049 2.24 ENSDART00000151748
aff4
AF4/FMR2 family, member 4
chr13_-_22877318 2.14 ENSDART00000057638
ENSDART00000171778
hk1
hexokinase 1
chr12_+_16845837 2.12 ENSDART00000138174
slc16a12b
solute carrier family 16, member 12b
chr23_-_26150495 2.11 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr21_-_28486800 2.08 ENSDART00000077910
epdl2
ependymin-like 2
chr2_-_9950224 2.02 ENSDART00000146407
si:ch1073-170o4.1
si:ch1073-170o4.1
chr9_-_30437160 1.95 ENSDART00000147241
BX936337.1
ENSDARG00000092870
chr3_+_27684309 1.89

chr23_-_31502149 1.86 ENSDART00000053545
zgc:153284
zgc:153284
chr7_+_13753344 1.81

chr19_+_32183937 1.77 ENSDART00000147474
stmn2b
stathmin 2b
chr9_-_12653481 1.73 ENSDART00000122558
tspearb
thrombospondin-type laminin G domain and EAR repeats b
chr2_+_2259793 1.69 ENSDART00000109073
dsg2l
desmoglein 2 like
chr24_-_12794672 1.61 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr7_+_39116005 1.54 ENSDART00000146702
tnni2b.2
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr10_+_31336284 1.54 ENSDART00000140988
tmem218
transmembrane protein 218
chr14_+_4169846 1.51 ENSDART00000038301
gnpda2
glucosamine-6-phosphate deaminase 2
chr23_-_20837809 1.44 ENSDART00000089750
znf362b
zinc finger protein 362b
chr6_-_39311711 1.42

chr1_-_11591843 1.37 ENSDART00000003825
cplx2l
complexin 2, like
chr14_+_34207218 1.36 ENSDART00000135608
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
chr11_+_666006 1.34 ENSDART00000130839
timp4.1
TIMP metallopeptidase inhibitor 4, tandem duplicate 1
chr21_+_21337628 1.32 ENSDART00000136325
rtn2b
reticulon 2b
chr8_-_41194530 1.25 ENSDART00000173055
fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chr7_-_18791134 1.24 ENSDART00000158796
fcer1g
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr8_+_28513670 1.22 ENSDART00000110291
srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr7_+_42124857 1.21 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr3_+_25992836 1.17 ENSDART00000010477
hsp70.3
heat shock cognate 70-kd protein, tandem duplicate 3
chr16_-_30606364 1.16 ENSDART00000147986
lmna
lamin A
KN150670v1_-_32201 1.15

chr2_-_21960233 1.13 ENSDART00000027587
ralab
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr11_-_33697442 1.12 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr18_+_14627030 1.11 ENSDART00000080788
wfdc1
WAP four-disulfide core domain 1
chr12_-_3903961 1.09 ENSDART00000134292
ENSDARG00000021154
ENSDARG00000021154
chr7_-_25426346 1.09 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr14_+_34440699 1.09 ENSDART00000130469
sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr5_-_18548689 1.06 ENSDART00000137802
fam214b
family with sequence similarity 214, member B
chr5_-_37335445 1.05 ENSDART00000141233
scn4bb
sodium channel, voltage-gated, type IV, beta b
chr8_-_50299273 1.05 ENSDART00000023639
nkx2.7
NK2 transcription factor related 7
chr1_-_11591684 1.02 ENSDART00000003825
cplx2l
complexin 2, like
chr5_-_64315770 0.99 ENSDART00000169287
zgc:110283
zgc:110283
chr16_+_13964949 0.97 ENSDART00000143983
zgc:174888
zgc:174888
chr23_+_7445760 0.97 ENSDART00000012194
gata5
GATA binding protein 5
chr11_-_39864306 0.96 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr7_+_23604092 0.95 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr20_+_18762031 0.95 ENSDART00000152136
ENSDART00000126959
tnfaip2a
tumor necrosis factor, alpha-induced protein 2a
chr3_-_28120668 0.94

chr13_-_22901327 0.93 ENSDART00000056523
hkdc1
hexokinase domain containing 1
chr10_+_26786051 0.90 ENSDART00000100329
f9b
coagulation factor IXb
chr12_-_28671833 0.88

chr1_-_51862897 0.87 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr16_+_7745309 0.87 ENSDART00000081418
ENSDART00000149404
bves
blood vessel epicardial substance
chr3_+_27477793 0.86

chr14_+_34440799 0.86 ENSDART00000173371
sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr12_+_7421078 0.86 ENSDART00000163114
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr15_-_2079036 0.80 ENSDART00000112946
dock10
dedicator of cytokinesis 10
chr1_+_18610282 0.78 ENSDART00000129970
si:dkeyp-118a3.2
si:dkeyp-118a3.2
chr11_-_39864543 0.78 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
chr20_+_18841440 0.77 ENSDART00000174532
fam167ab
family with sequence similarity 167, member Ab
chr6_-_39311594 0.76

chr17_-_50343403 0.75 ENSDART00000140121
si:ch211-235i11.5
si:ch211-235i11.5
chr2_+_26161204 0.74 ENSDART00000078639
slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr16_-_31476944 0.69 ENSDART00000167350
zgc:194210
zgc:194210
chr24_+_21876490 0.68 ENSDART00000081234
ropn1l
rhophilin associated tail protein 1-like
chr6_-_40747134 0.65 ENSDART00000154916
p4htm
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr18_+_17548213 0.62 ENSDART00000144960
nup93
nucleoporin 93
chr4_+_5308883 0.62 ENSDART00000150366
si:ch211-214j24.10
si:ch211-214j24.10
chr24_-_42120772 0.60 ENSDART00000166413
ENSDART00000166414
ssr1
signal sequence receptor, alpha
chr2_+_38390887 0.59 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr19_-_9793444 0.58 ENSDART00000134816
slc2a3a
solute carrier family 2 (facilitated glucose transporter), member 3a
chr10_+_877701 0.57 ENSDART00000176303
FO704646.1
ENSDARG00000107355
chr10_+_13320935 0.57 ENSDART00000135082
tmem267
transmembrane protein 267
chr18_-_16934961 0.57 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr21_+_19311031 0.57 ENSDART00000093155
hpse
heparanase
chr7_-_6280179 0.55 ENSDART00000173349
CU457819.3
Histone H3.2
chr11_-_40415291 0.50

chr11_+_23012136 0.48 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr19_+_7535067 0.46 ENSDART00000147491
fam63a
family with sequence similarity 63, member A
chr18_+_12452 0.45

chr17_-_14956738 0.43

chr19_+_32184149 0.43 ENSDART00000078299
stmn2b
stathmin 2b
chr5_-_38022706 0.43

chr4_+_23406078 0.41 ENSDART00000139543
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr9_-_12063411 0.39 ENSDART00000038651
znf804a
zinc finger protein 804A
chr11_+_44922098 0.37 ENSDART00000172999
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr4_+_15607042 0.37 ENSDART00000101619
ENSDART00000021384
exoc4
exocyst complex component 4
chr8_-_14014576 0.36 ENSDART00000135811
atp2b3a
ATPase, Ca++ transporting, plasma membrane 3a
chr19_+_7535152 0.35 ENSDART00000136502
fam63a
family with sequence similarity 63, member A
chr11_+_40280114 0.34 ENSDART00000175424
mmel1
membrane metallo-endopeptidase-like 1
chr1_-_11591631 0.34 ENSDART00000142122
cplx2l
complexin 2, like
chr3_+_15245529 0.33

chr17_+_33862300 0.33

chr10_+_877636 0.33 ENSDART00000176303
FO704646.1
ENSDARG00000107355
chr3_-_28120760 0.32

chr1_-_6403371 0.31

chr12_-_151380 0.31

chr8_+_36888422 0.30

chr22_-_38530581 0.30 ENSDART00000151785
klc4
kinesin light chain 4
chr4_+_13451169 0.29 ENSDART00000172552
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr17_-_31562669 0.28 ENSDART00000110167
rpap1
RNA polymerase II associated protein 1
KN150670v1_-_31884 0.27

chr8_+_5546852 0.27

chr10_+_38764480 0.26 ENSDART00000172306
ENSDART00000163099
tmprss2
transmembrane protease, serine 2
chr11_-_39864489 0.25 ENSDART00000165781
fam83e
family with sequence similarity 83, member E
KN149949v1_+_25867 0.25

chr14_+_26424717 0.25

chr20_-_24047119 0.24 ENSDART00000143005
mdn1
midasin AAA ATPase 1
chr14_-_2284860 0.23 ENSDART00000124171
si:dkeyp-115d7.2
si:dkeyp-115d7.2
KN149949v1_+_25953 0.23

chr21_-_45647945 0.23

chr12_-_30898555 0.23

chr25_-_34540270 0.22 ENSDART00000156508
zgc:114046
zgc:114046
chr24_+_3177066 0.22

chr14_+_4169371 0.21 ENSDART00000136665
gnpda2
glucosamine-6-phosphate deaminase 2
chr8_-_11732343 0.21 ENSDART00000091684
anapc7
anaphase promoting complex subunit 7
KN149797v1_-_70680 0.20 ENSDART00000170785
CABZ01113193.1
uncharacterized protein LOC795664 precursor
chr12_-_30898994 0.19

chr23_-_3467855 0.17

chr6_-_26905146 0.14 ENSDART00000011863
hdlbpa
high density lipoprotein binding protein a
chr1_-_51863187 0.14 ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr18_+_10957421 0.13 ENSDART00000166561
ttc38
tetratricopeptide repeat domain 38
chr13_-_25068717 0.13 ENSDART00000057605
adka
adenosine kinase a
chr15_+_29842298 0.13

chr12_-_1018688 0.11 ENSDART00000054353
ENSDARG00000037357
ENSDARG00000037357
chr11_+_42474134 0.11 ENSDART00000156080
tdrd3
tudor domain containing 3
chr19_-_35841625 0.11 ENSDART00000169006
ak2
adenylate kinase 2
chr11_-_40414664 0.10 ENSDART00000165163
si:ch211-222l21.1
si:ch211-222l21.1
chr17_-_51173358 0.09 ENSDART00000169050
trappc12
trafficking protein particle complex 12
chr24_+_14095643 0.09 ENSDART00000124740
ncoa2
nuclear receptor coactivator 2
chr3_+_27188961 0.08

chr5_-_30434967 0.08 ENSDART00000086534
cyb5d2
cytochrome b5 domain containing 2
chr20_+_54544931 0.08

chr21_-_5228529 0.07 ENSDART00000146061
psmd5
proteasome 26S subunit, non-ATPase 5
chr21_-_43332911 0.06 ENSDART00000114955
sowahaa
sosondowah ankyrin repeat domain family member Aa
chr4_-_23405867 0.05

chr12_+_33716314 0.04 ENSDART00000111486
mrpl43
mitochondrial ribosomal protein L43
chr23_-_887934 0.03

chr14_+_20927461 0.03 ENSDART00000160576
si:ch211-175m2.4
si:ch211-175m2.4
chr17_-_31027949 0.03 ENSDART00000152016
eml1
echinoderm microtubule associated protein like 1
chr7_+_49780512 0.03 ENSDART00000174308
LRRC4C
leucine rich repeat containing 4C
chr12_-_3904030 0.02 ENSDART00000134292
ENSDARG00000021154
ENSDARG00000021154
chr7_+_41141295 0.01 ENSDART00000083967
chpf2
chondroitin polymerizing factor 2
chr6_-_33940469 0.00 ENSDART00000137268
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0071549 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.9 2.6 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.8 2.5 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.5 2.4 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.4 1.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 1.1 GO:0002280 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.3 1.7 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.3 2.1 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.3 6.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 1.0 GO:0009886 post-embryonic morphogenesis(GO:0009886) post-embryonic foregut morphogenesis(GO:0048618)
0.2 2.9 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.2 0.9 GO:0001919 regulation of receptor recycling(GO:0001919) response to ischemia(GO:0002931)
0.2 2.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 3.2 GO:0032526 response to retinoic acid(GO:0032526)
0.2 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.2 1.2 GO:0090342 regulation of cell aging(GO:0090342)
0.2 1.0 GO:0051601 exocyst localization(GO:0051601)
0.2 0.6 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.2 3.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.4 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.1 1.0 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 2.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.2 GO:0042026 protein refolding(GO:0042026)
0.1 2.7 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 2.2 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 2.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 2.2 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 3.8 GO:0007601 visual perception(GO:0007601)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.7 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 2.0 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 1.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 2.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 2.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.4 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.9 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0048747 muscle fiber development(GO:0048747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 2.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.3 6.9 GO:0005861 troponin complex(GO:0005861)
0.3 1.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 2.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 2.7 GO:0043195 terminal bouton(GO:0043195)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.1 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0000145 exocyst(GO:0000145)
0.1 2.2 GO:0030426 growth cone(GO:0030426)
0.1 2.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 10.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0031514 motile cilium(GO:0031514)
0.0 2.5 GO:0009986 cell surface(GO:0009986)
0.0 1.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 3.2 GO:0048039 ubiquinone binding(GO:0048039)
0.5 2.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 2.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.4 2.3 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.4 2.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.7 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.3 2.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 1.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 2.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 3.2 GO:0005518 collagen binding(GO:0005518)
0.1 2.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 3.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.7 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 4.1 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.9 GO:0030552 cAMP binding(GO:0030552)
0.1 1.9 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 2.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.1 3.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 3.2 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.2 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0005516 calmodulin binding(GO:0005516)
0.0 2.0 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.9 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 1.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 7.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 2.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 5.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.8 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 3.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)