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Results for mafb+nrl

Z-value: 1.59

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Transcription factors associated with mafb+nrl

Gene Symbol Gene ID Gene Info
mafb
ENSDARG00000076520 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
nrl
ENSDARG00000100466 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrldr10_dc_chr23_-_45707212_457072160.844.6e-05Click!

Activity profile of mafb+nrl motif

Sorted Z-values of mafb+nrl motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mafb+nrl

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_70948223 3.53 ENSDART00000013404
ak1
adenylate kinase 1
chr3_-_54893038 3.43 ENSDART00000155871
ENSDART00000109016
hbae3
hemoglobin alpha embryonic-3
chr22_-_613948 3.22 ENSDART00000148692
apobec2a
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr1_+_43738350 2.94 ENSDART00000127087
ENSDART00000100309
crybb1l2
crystallin, beta B1, like 2
chr1_-_58580939 2.84 ENSDART00000158011
col5a3b
collagen, type V, alpha 3b
chr19_-_5429428 2.82 ENSDART00000066620
ENSDART00000151398
krtt1c19e
keratin type 1 c19e
chr20_+_12559243 2.78 ENSDART00000172370
si:dkey-269i1.4
si:dkey-269i1.4
chr21_+_21337628 2.67 ENSDART00000136325
rtn2b
reticulon 2b
chr3_-_32686790 2.43 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr3_-_60953138 2.30 ENSDART00000028219
pvalb4
parvalbumin 4
chr16_+_5470544 2.28

chr21_+_40082890 2.27 ENSDART00000100166
serpinf1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
KN150074v1_-_1031 2.25

chr21_-_99353 2.24 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr24_+_38371710 2.23 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr7_+_58718614 2.22 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr9_-_7560915 2.21 ENSDART00000081553
desma
desmin a
chr7_-_24428781 2.19 ENSDART00000052802
calb2b
calbindin 2b
chr7_+_38895198 2.19 ENSDART00000052318
mdka
midkine a
chr23_-_26150495 2.14 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr19_-_5338129 2.07 ENSDART00000081951
stx1b
syntaxin 1B
chr16_-_39951493 1.98

chr7_-_25816549 1.95 ENSDART00000052989
ENSDART00000047951
ache
acetylcholinesterase
chr11_+_14142126 1.88 ENSDART00000102520
palm1a
paralemmin 1a
chr7_-_25816655 1.86 ENSDART00000052989
ENSDART00000047951
ache
acetylcholinesterase
chr21_+_41684338 1.77 ENSDART00000169511
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr6_-_60152693 1.76 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr10_+_38831967 1.76 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr15_-_31687 1.73

chr6_-_60152594 1.73 ENSDART00000083453
slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr24_-_26138298 1.68 ENSDART00000128618
and1
actinodin1
chr7_-_35438739 1.66 ENSDART00000043857
irx5a
iroquois homeobox 5a
chr24_-_12794672 1.65 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr9_-_42894582 1.64 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr6_+_55022668 1.63 ENSDART00000158845
mybphb
myosin binding protein Hb
chr3_-_28120668 1.63

chr20_+_45531190 1.62

chr22_+_26543146 1.61

chr22_-_120677 1.58

chr24_-_41448993 1.58 ENSDART00000041349
crygn2
crystallin, gamma N2
chr6_-_39315024 1.57 ENSDART00000012644
krt4
keratin 4
chr7_+_16583234 1.57 ENSDART00000173580
nav2a
neuron navigator 2a
chr14_+_33117964 1.56 ENSDART00000075278
atp1b4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr19_-_5416317 1.51 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr15_-_31871 1.48

chr8_-_38126693 1.46 ENSDART00000112331
adgra2
adhesion G protein-coupled receptor A2
chr7_+_50491026 1.45 ENSDART00000165037
si:ch73-380l10.2
si:ch73-380l10.2
chr9_-_22371512 1.44 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr9_-_22507592 1.44 ENSDART00000132029
crygm2d2
crystallin, gamma M2d2
chr19_+_48499602 1.44

chr10_-_26782374 1.43 ENSDART00000162710
fgf13b
fibroblast growth factor 13b
chr24_-_12794564 1.42 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr12_-_7790348 1.41 ENSDART00000148673
ank3b
ankyrin 3b
chr17_+_29328653 1.38 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr20_-_21031504 1.38 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr21_-_34623741 1.37 ENSDART00000023038
dacha
dachshund a
chr15_-_4322875 1.36 ENSDART00000173311
si:ch211-117a13.2
si:ch211-117a13.2
chr20_-_5009037 1.35 ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr2_+_393439 1.34 ENSDART00000122138
mylk4a
myosin light chain kinase family, member 4a
chr12_+_7421078 1.34 ENSDART00000163114
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr19_+_33235375 1.34 ENSDART00000052096
hrsp12
heat-responsive protein 12
chr23_-_3466041 1.33 ENSDART00000002309
mafba
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr25_+_4918339 1.33 ENSDART00000153980
parvb
parvin, beta
chr17_-_45383925 1.32

chr12_+_27032862 1.31

chr22_+_12327849 1.29 ENSDART00000178678
FO704572.1
ENSDARG00000106890
chr6_-_39311711 1.28

chr9_+_31079790 1.28 ENSDART00000101070
dachd
dachshund d
chr10_+_38831925 1.27 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr12_-_308929 1.27 ENSDART00000066579
ENSDART00000171396
pts
6-pyruvoyltetrahydropterin synthase
chr5_-_20527105 1.27 ENSDART00000133461
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr14_-_41311458 1.27 ENSDART00000163039
fgfrl1b
fibroblast growth factor receptor-like 1b
chr22_-_10430130 1.26 ENSDART00000064801
ogn
osteoglycin
chr9_+_39217373 1.26 ENSDART00000004742
cps1
carbamoyl-phosphate synthase 1, mitochondrial
chr17_+_44666606 1.25 ENSDART00000155096
tmem63c
transmembrane protein 63C
chr12_-_37921731 1.25

chr9_+_25964943 1.23 ENSDART00000147229
ENSDART00000127834
zeb2a
zinc finger E-box binding homeobox 2a
chr13_-_49826330 1.23 ENSDART00000099475
nid1a
nidogen 1a
chr13_-_869704 1.23

chr16_+_46145286 1.22 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr16_+_24069711 1.20 ENSDART00000142869
apoc2
apolipoprotein C-II
chr6_+_58549236 1.19 ENSDART00000157018
stmn3
stathmin-like 3
chr16_-_42990753 1.19 ENSDART00000149317
hfe2
hemochromatosis type 2
chr1_-_24747855 1.19 ENSDART00000111686
fhdc1
FH2 domain containing 1
chr21_-_43020159 1.18 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr21_-_1600125 1.18 ENSDART00000066621
vmo1b
vitelline membrane outer layer 1 homolog b
chr4_+_26507297 1.16 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
KN149978v1_-_10669 1.16 ENSDART00000175723
CABZ01068178.1
ENSDARG00000105971
chr5_-_63487161 1.15 ENSDART00000048395
cmlc1
cardiac myosin light chain-1
chr8_+_50994889 1.15 ENSDART00000142061
si:dkey-32e23.4
si:dkey-32e23.4
chr15_+_24277664 1.15 ENSDART00000155502
sez6b
seizure related 6 homolog b
chr4_+_3970874 1.14 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr25_-_34748472 1.14

chr17_-_50140718 1.14 ENSDART00000058707
jdp2a
Jun dimerization protein 2a
chr2_+_31974269 1.13 ENSDART00000012413
ankhb
ANKH inorganic pyrophosphate transport regulator b
chr15_-_41288480 1.13 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr24_-_475010 1.13 ENSDART00000108762
vopp1
vesicular, overexpressed in cancer, prosurvival protein 1
chr13_-_26907910 1.12 ENSDART00000146712
ccdc85a
coiled-coil domain containing 85A
chr13_-_25153833 1.12 ENSDART00000039828
ENSDART00000110304
vcla
vinculin a
chr9_-_29056763 1.12 ENSDART00000060321
ENSDARG00000056704
ENSDARG00000056704
chr9_+_49961721 1.12

chr10_+_1384178 1.12 ENSDART00000150096
gdnfa
glial cell derived neurotrophic factor a
chr8_-_14014576 1.11 ENSDART00000135811
atp2b3a
ATPase, Ca++ transporting, plasma membrane 3a
chr6_-_39312306 1.11

chr9_+_21908880 1.10

chr23_+_25782195 1.09 ENSDART00000060059
rbms2b
RNA binding motif, single stranded interacting protein 2b
chr8_-_24991984 1.08 ENSDART00000078795
ahcyl1
adenosylhomocysteinase-like 1
chr18_+_45893199 1.08 ENSDART00000158246
dvl3b
dishevelled segment polarity protein 3b
chr16_-_48672056 1.07

chr23_+_23559246 1.07 ENSDART00000172214
agrn
agrin
chr2_+_3864843 1.06 ENSDART00000108964
ENSDART00000128514
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr18_+_20504980 1.06 ENSDART00000060295
rapsn
receptor-associated protein of the synapse, 43kD
chr19_+_1797470 1.06

chr2_-_44402486 1.05 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr4_+_377829 1.05 ENSDART00000030215
rpl18a
ribosomal protein L18a
chr25_+_16505438 1.05 ENSDART00000008986
atp6v1e1a
ATPase, H+ transporting, lysosomal, V1 subunit E1a
chr7_+_10792973 1.05

chr8_-_50899451 1.05 ENSDART00000053750
acsl2
acyl-CoA synthetase long-chain family member 2
chr16_+_5625301 1.04

chr5_+_296856 1.04

chr5_-_12025080 1.03 ENSDART00000164190
ksr2
kinase suppressor of ras 2
chr1_-_43733382 1.02 ENSDART00000023642
cryba1l2
crystallin, beta A1, like 2
chr21_-_5852663 1.01 ENSDART00000130521
CACFD1
calcium channel flower domain containing 1
chr4_-_25847471 1.01 ENSDART00000142491
ndufa12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
KN150108v1_+_18276 1.00

chr9_-_44493074 1.00 ENSDART00000167685
neurod1
neuronal differentiation 1
chr9_+_54692834 1.00

chr5_-_1698166 0.99 ENSDART00000073462
rplp0
ribosomal protein, large, P0
chr14_-_16816075 0.99 ENSDART00000060479
smtnl1
smoothelin-like 1
chr4_-_22130388 0.99 ENSDART00000019748
lin7a
lin-7 homolog A (C. elegans)
KN149760v1_-_29067 0.99

chr4_+_19545842 0.99 ENSDART00000140028
lrrc4.1
leucine rich repeat containing 4.1
chr6_-_60088120 0.99

chr24_-_4941954 0.98 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr4_+_119964 0.98 ENSDART00000177177
ENSDART00000159996
tbk1
TANK-binding kinase 1
chr25_+_30838768 0.98

chr19_+_9085377 0.98 ENSDART00000091443
ENSDARG00000062900
ENSDARG00000062900
chr13_-_24248675 0.97 ENSDART00000046360
rhoua
ras homolog family member Ua
chr25_+_36872560 0.97 ENSDART00000163178
slc10a3
solute carrier family 10, member 3
chr13_-_18812889 0.97

chr7_+_23604092 0.97 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr7_-_25816498 0.97 ENSDART00000052989
ENSDART00000047951
ache
acetylcholinesterase
chr20_+_48971948 0.96 ENSDART00000164006
nkx2.4b
NK2 homeobox 4b
chr12_+_4821529 0.96

chr24_-_21353742 0.95 ENSDART00000153695
atp8a2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr9_-_561224 0.95

chr1_+_6995893 0.94 ENSDART00000163488
en1b
engrailed homeobox 1b
chr12_-_552235 0.94 ENSDART00000168586
ENSDART00000158355
bsk146
brain specific kinase 146
chr7_-_25426346 0.94 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr2_+_7054686 0.94 ENSDART00000057385
nos1apb
nitric oxide synthase 1 (neuronal) adaptor protein b
chr16_+_5470419 0.93

chr10_-_44527708 0.93

chr7_-_12715948 0.93 ENSDART00000173115
rplp2l
ribosomal protein, large P2, like
chr16_+_28449134 0.93 ENSDART00000059044
itga8
integrin, alpha 8
chr15_+_16961487 0.93 ENSDART00000154679
ypel2b
yippee-like 2b
chr12_-_7902815 0.92 ENSDART00000088100
ank3b
ankyrin 3b
chr10_+_38582701 0.92 ENSDART00000144329
acer3
alkaline ceramidase 3
chr6_+_4379989 0.92 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr17_-_32683561 0.90 ENSDART00000155002
cgref1
cell growth regulator with EF-hand domain 1
KN150680v1_+_10854 0.90

chr24_+_17112303 0.90 ENSDART00000131577
commd3
COMM domain containing 3
chr11_+_6809190 0.89 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr23_-_20402258 0.89 ENSDART00000136204
CR749762.2
ENSDARG00000093223
chr3_-_56474209 0.88 ENSDART00000156398
si:ch211-189a21.1
si:ch211-189a21.1
chr24_+_9605832 0.88 ENSDART00000131891
tmem108
transmembrane protein 108
chr1_-_57300743 0.88 ENSDART00000081122
COLGALT1 (1 of many)
collagen beta(1-O)galactosyltransferase 1
chr11_+_29913942 0.88 ENSDART00000157385
cdkl5
cyclin-dependent kinase-like 5
chr18_+_9228336 0.88

chr15_+_3296905 0.87 ENSDART00000171723
foxo1a
forkhead box O1 a
chr17_-_32683664 0.87 ENSDART00000109927
cgref1
cell growth regulator with EF-hand domain 1
chr6_-_39311594 0.87

chr11_+_6754335 0.87 ENSDART00000104292
pde4cb
phosphodiesterase 4C, cAMP-specific b
chr22_+_31866783 0.87 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr20_-_20634087 0.87 ENSDART00000125039
six6b
SIX homeobox 6b
chr25_-_8475902 0.86 ENSDART00000176751
CU929451.3
ENSDARG00000107886
chr9_-_47957181 0.86 ENSDART00000015159
tns1b
tensin 1b
chr4_-_37424443 0.86

chr2_+_35745559 0.86 ENSDART00000002094
ankrd45
ankyrin repeat domain 45
chr3_+_17210396 0.85 ENSDART00000090676
si:ch211-210g13.5
si:ch211-210g13.5
chr14_-_16815986 0.85 ENSDART00000060479
smtnl1
smoothelin-like 1
chr7_+_36213100 0.85 ENSDART00000173595
chd9
chromodomain helicase DNA binding protein 9
chr19_+_156649 0.84 ENSDART00000167717
lrrc16a
leucine rich repeat containing 16A
chr1_+_2074153 0.84 ENSDART00000058877
rap2ab
RAP2A, member of RAS oncogene family b
chr17_-_37266525 0.84 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr18_-_8697347 0.84 ENSDART00000093131
FRMD4A
FERM domain containing 4A
chr21_-_38534139 0.84 ENSDART00000148939
pof1b
premature ovarian failure, 1B
chr21_-_22435721 0.84

chr9_-_12063411 0.84 ENSDART00000038651
znf804a
zinc finger protein 804A
chr24_+_37834148 0.83

chr14_-_16762762 0.83 ENSDART00000106333
phox2bb
paired-like homeobox 2bb
chr6_-_39315608 0.83 ENSDART00000012644
krt4
keratin 4
chr6_+_60152913 0.83

chr20_-_35938683 0.83 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr19_-_27730419 0.82 ENSDART00000151047
sh3bp5lb
SH3-binding domain protein 5-like, b
chr17_+_53162459 0.82

chr19_-_22904687 0.82 ENSDART00000141503
pleca
plectin a
chr6_-_43094573 0.82 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr9_-_23406315 0.82 ENSDART00000159256
kif5c
kinesin family member 5C
chr8_-_15267816 0.82 ENSDART00000137923
spata6
spermatogenesis associated 6
chr16_+_21098948 0.82 ENSDART00000006043
hoxa11b
homeobox A11b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0006581 response to amphetamine(GO:0001975) acetylcholine catabolic process(GO:0006581) response to amine(GO:0014075)
1.1 3.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.9 2.8 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.8 3.1 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.7 2.2 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.7 3.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.7 2.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.7 4.0 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.6 2.3 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.5 1.5 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.5 1.4 GO:0061549 sympathetic ganglion development(GO:0061549)
0.4 1.3 GO:0021742 abducens nucleus development(GO:0021742)
0.4 1.2 GO:0051580 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.4 1.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.4 2.2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.4 1.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 1.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.4 1.1 GO:0010084 specification of organ axis polarity(GO:0010084)
0.3 2.0 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.3 1.3 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.3 0.9 GO:0050765 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.3 3.4 GO:0015671 oxygen transport(GO:0015671)
0.3 0.9 GO:0097484 dendrite extension(GO:0097484)
0.3 0.9 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.3 0.8 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 1.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.2 1.7 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.2 1.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.7 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.2 0.9 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.2 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.6 GO:0060220 blood vessel maturation(GO:0001955) retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 0.8 GO:0050687 negative regulation of response to biotic stimulus(GO:0002832) negative regulation of defense response to virus(GO:0050687)
0.2 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.2 1.3 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 0.6 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.2 0.6 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 1.8 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 1.6 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 3.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.2 1.2 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.2 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.2 0.8 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.2 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.1 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.3 GO:0035094 response to nicotine(GO:0035094)
0.1 1.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.6 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.8 GO:1902946 protein localization to early endosome(GO:1902946)
0.1 1.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 2.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 3.5 GO:0003094 glomerular filtration(GO:0003094)
0.1 1.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.4 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:0051701 interaction with host(GO:0051701)
0.1 8.1 GO:0007601 visual perception(GO:0007601)
0.1 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 1.1 GO:0086001 cardiac muscle cell action potential(GO:0086001)
0.1 0.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.3 GO:0030431 sleep(GO:0030431)
0.1 2.2 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 0.5 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 0.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.9 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.3 GO:0070544 histone H3-K4 demethylation(GO:0034720) histone H3-K36 demethylation(GO:0070544)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 2.3 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 0.8 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 2.1 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.1 0.3 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.7 GO:0042551 neuron maturation(GO:0042551)
0.1 1.0 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.6 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.8 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 2.2 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.4 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.7 GO:0035141 medial fin morphogenesis(GO:0035141)
0.1 0.4 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:0003139 secondary heart field specification(GO:0003139)
0.1 0.4 GO:1901655 cellular response to ketone(GO:1901655)
0.1 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.2 GO:0070861 regulation of COPII vesicle coating(GO:0003400) regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 0.3 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 0.3 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 1.0 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 2.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:1902914 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.2 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of calcium ion transmembrane transport(GO:1904427) positive regulation of cation channel activity(GO:2001259)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 1.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:2000136 cell proliferation involved in heart morphogenesis(GO:0061323) regulation of cell proliferation involved in heart morphogenesis(GO:2000136)
0.0 1.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 3.3 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.8 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.6 GO:0051181 cofactor transport(GO:0051181)
0.0 1.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 1.7 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0090148 membrane fission(GO:0090148)
0.0 0.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.6 GO:0006813 potassium ion transport(GO:0006813)
0.0 1.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0097306 cellular response to alcohol(GO:0097306)
0.0 0.3 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 3.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0060030 dorsal convergence(GO:0060030)
0.0 1.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 1.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.9 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.7 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.8 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0044839 G2/M transition of mitotic cell cycle(GO:0000086) cell cycle G2/M phase transition(GO:0044839)
0.0 0.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.1 GO:0048009 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.5 GO:0006821 chloride transport(GO:0006821)
0.0 0.7 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 3.4 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.3 3.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 0.8 GO:0097224 sperm connecting piece(GO:0097224)
0.2 2.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.2 GO:0042627 chylomicron(GO:0042627)
0.2 1.4 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.2 1.6 GO:0098533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.2 0.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.2 GO:0043195 terminal bouton(GO:0043195)
0.2 0.5 GO:0043291 RAVE complex(GO:0043291)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.6 GO:0016234 inclusion body(GO:0016234)
0.1 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0046930 pore complex(GO:0046930)
0.1 4.3 GO:0005604 basement membrane(GO:0005604) extracellular matrix component(GO:0044420)
0.1 0.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 3.0 GO:0030426 growth cone(GO:0030426)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 5.2 GO:0005882 intermediate filament(GO:0005882)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.8 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0043679 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 3.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 1.3 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 10.3 GO:0043005 neuron projection(GO:0043005)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.6 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 14.3 GO:0005576 extracellular region(GO:0005576)
0.0 0.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0030055 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 7.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.1 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
1.2 3.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
1.1 3.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.9 2.8 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.8 3.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.7 2.2 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.5 3.4 GO:0031720 haptoglobin binding(GO:0031720)
0.4 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 1.3 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.4 4.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 1.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.3 1.0 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.3 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.3 1.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 8.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 1.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 0.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.2 0.7 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.2 1.1 GO:0016801 hydrolase activity, acting on ether bonds(GO:0016801)
0.2 0.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.2 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 3.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 1.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 2.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.8 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2 1.1 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.1 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.1 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 1.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.3 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.5 GO:0043236 laminin binding(GO:0043236)
0.1 1.6 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.1 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.6 GO:0042562 hormone binding(GO:0042562)
0.1 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.4 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 4.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.4 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 3.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0019201 nucleotide kinase activity(GO:0019201)
0.1 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.2 GO:0052725 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.8 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 1.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 14.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210) quaternary ammonium group binding(GO:0050997)
0.0 1.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 5.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 2.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 4.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 3.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 4.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 1.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.0 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.8 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.1 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein