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Results for mafk

Z-value: 1.82

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Transcription factors associated with mafk

Gene Symbol Gene ID Gene Info
ENSDARG00000100947 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafkdr10_dc_chr3_-_42275696_422758070.852.9e-05Click!

Activity profile of mafk motif

Sorted Z-values of mafk motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mafk

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_25886553 7.83 ENSDART00000030890
heme oxygenase 1a
chr3_-_32686790 7.06 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr16_-_9978112 5.72 ENSDART00000149312
neurocalcin delta a
chr5_-_66792947 4.90 ENSDART00000147009
si:dkey-251i10.2
chr11_+_26371444 4.78 ENSDART00000042322
microtubule-associated protein 1 light chain 3 alpha
chr19_-_7501777 4.75 ENSDART00000081741
RAB25, member RAS oncogene family a
chr6_-_39661423 4.72 ENSDART00000110380
La ribonucleoprotein domain family, member 4Ab
chr8_-_17480730 4.53 ENSDART00000100667
v-ski avian sarcoma viral oncogene homolog a
chr20_+_34423970 4.16 ENSDART00000061659
influenza virus NS1A binding protein a
chr14_+_11151485 4.04 ENSDART00000169202
si:ch211-153b23.5
chr5_+_42312784 4.00 ENSDART00000039973
RUN and FYVE domain containing 3
chr9_+_21581061 3.90

chr4_-_2615160 3.52 ENSDART00000140760
E2F transcription factor 7
chr5_-_30015572 3.32 ENSDART00000147769
si:ch211-117m20.5
chr15_-_24987099 3.31

chr16_-_16274298 3.30 ENSDART00000103815
stathmin 2a
chr5_+_36487425 3.30 ENSDART00000049900
transgelin 2
chr9_-_24431684 3.23 ENSDART00000039399
caveolae associated protein 2a
chr13_+_2774422 3.22 ENSDART00000162362
wu:fj16a03
chr23_+_19887319 3.20 ENSDART00000139192
emerin (Emery-Dreifuss muscular dystrophy)
chr10_+_38831967 3.18 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr2_-_1677190 3.17 ENSDART00000024135
tubulin, beta 2A class IIa
chr11_-_2107054 3.10 ENSDART00000173031
homeobox C6b
chr19_+_32183937 3.09 ENSDART00000147474
stathmin 2b
chr22_+_21997000 3.04 ENSDART00000046174
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr5_+_65267043 3.00 ENSDART00000161578
myomaker, myoblast fusion factor
chr20_-_39200252 2.96 ENSDART00000037318
ENSDART00000143379
regulator of calcineurin 2
chr7_+_23843682 2.90 ENSDART00000173899
mitochondrial ribosomal protein L52
chr23_+_26215871 2.86 ENSDART00000158878
protein tyrosine phosphatase, non-receptor type 22
chr23_+_10412852 2.86 ENSDART00000142595
keratin 18
chr14_+_34440699 2.81 ENSDART00000130469
SH3 domain and tetratricopeptide repeats 2
chr15_+_29343644 2.79 ENSDART00000170537
ENSDART00000128973
RAP1 GTPase activating protein 2a
chr12_-_1931281 2.75 ENSDART00000005676
ENSDART00000127937
SRY (sex determining region Y)-box 9a
chr5_+_64225977 2.72 ENSDART00000122863
prostaglandin-endoperoxide synthase 1
chr1_-_51862897 2.64 ENSDART00000136469
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr21_-_41001910 2.60 ENSDART00000142277
PLAC8-like 1
chr9_+_41301317 2.59 ENSDART00000000250
solute carrier family 40 (iron-regulated transporter), member 1
chr21_+_30757831 2.55 ENSDART00000139486
ENSDARG00000030006
chr24_+_30343717 2.52 ENSDART00000162377
ENSDARG00000100270
chr3_+_25933164 2.51 ENSDART00000143697
si:dkeyp-69e1.8
chr12_+_38382027 2.50 ENSDART00000021069
ribosomal protein L38
chr11_-_32461160 2.48 ENSDART00000155592
protocadherin 17
chr9_-_3700395 2.44 ENSDART00000102900
Sp5 transcription factor a
chr23_-_27645138 2.43 ENSDART00000008174
phosphofructokinase, muscle a
chr7_+_56807833 2.43 ENSDART00000055956
enolase superfamily member 1
chr1_-_7456961 2.42 ENSDART00000152295
family with sequence similarity 83 member G
chr5_+_64226125 2.39 ENSDART00000122863
prostaglandin-endoperoxide synthase 1
chr19_-_23037220 2.38 ENSDART00000090669
plectin a
chr16_+_21109486 2.37 ENSDART00000079383
homeobox A9b
chr18_-_17031173 2.33 ENSDART00000129146
TBC1 domain family, member 15
chr14_+_34440799 2.33 ENSDART00000173371
SH3 domain and tetratricopeptide repeats 2
chr10_+_38831925 2.30 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr14_+_26137608 2.28 ENSDART00000175459
G protein-coupled receptor 137
chr21_-_23074223 2.27 ENSDART00000147896
ubiquitin specific peptidase 28
chr19_+_31817286 2.25 ENSDART00000078459
transmembrane protein 55A
chr16_-_17254837 2.24 ENSDART00000089386
intermediate filament family orphan 1b
chr25_-_22089794 2.24 ENSDART00000139110
plakophilin 3a
chr14_+_24543732 2.22 ENSDART00000106039
Rho guanine nucleotide exchange factor (GEF) 37
chr13_-_22877318 2.21 ENSDART00000057638
ENSDART00000171778
hexokinase 1
chr1_-_25272318 2.20 ENSDART00000134192
synaptopodin 2b
chr11_-_39864306 2.19 ENSDART00000165781
family with sequence similarity 83, member E
chr15_-_40391882 2.16

chr9_-_23307419 2.16 ENSDART00000020884
LY6/PLAUR domain containing 6
chr7_+_20046425 2.08 ENSDART00000131019
acyl-CoA dehydrogenase, very long chain
chr12_-_4648262 2.07 ENSDART00000152771
si:ch211-255p10.3
chr16_+_11138924 2.06 ENSDART00000091183
Ets2 repressor factor like 3
chr19_-_41819752 2.05 ENSDART00000167772
split hand/foot malformation (ectrodactyly) type 1
chr3_-_4395852 2.02 ENSDART00000158197
si:dkey-73p2.2
chr13_-_35908743 2.02 ENSDART00000133565
si:dkey-157l19.2
chr3_+_25992836 1.97 ENSDART00000010477
heat shock cognate 70-kd protein, tandem duplicate 3
chr20_+_51385187 1.97

chr16_+_11138879 1.95 ENSDART00000091183
Ets2 repressor factor like 3
chr5_-_37335445 1.94 ENSDART00000141233
sodium channel, voltage-gated, type IV, beta b
chr6_-_34951506 1.93

chr23_+_26995808 1.93

chr3_-_21149752 1.92 ENSDART00000003939
synaptogyrin 1a
chr10_+_31336284 1.86 ENSDART00000140988
transmembrane protein 218
chr14_-_31522323 1.84 ENSDART00000172870
RNA binding motif protein, X-linked
chr13_+_28689749 1.84 ENSDART00000101653
ENSDARG00000062790
chr8_-_15071283 1.83

chr20_-_25727145 1.83 ENSDART00000126716
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr23_+_14058972 1.83 ENSDART00000090864
leiomodin 3 (fetal)
chr2_-_25325686 1.82 ENSDART00000111212
NCK adaptor protein 1a
chr10_+_26786051 1.81 ENSDART00000100329
coagulation factor IXb
chr24_+_9073790 1.81

chr22_+_520496 1.79 ENSDART00000067638
mediator complex subunit 20
chr2_+_10023967 1.76 ENSDART00000148227
annexin A13, like
chr14_-_49600662 1.76 ENSDART00000161147
si:ch211-154c21.1
chr6_-_34951317 1.76

chr12_-_28248133 1.74 ENSDART00000016283
proteasome 26S subunit, non-ATPase 11b
chr6_+_12618821 1.72 ENSDART00000156341
family with sequence similarity 117, member Ba
chr12_+_2412047 1.71 ENSDART00000112032
Rho GTPase activating protein 22
chr8_-_50270783 1.71 ENSDART00000146056
NK3 homeobox 1
chr14_-_17282615 1.70 ENSDART00000006716
ENSDART00000136242
selenoprotein T, 2
chr14_+_47229400 1.70 ENSDART00000136045
microsomal glutathione S-transferase 2
chr21_+_5887486 1.70 ENSDART00000048399
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr24_-_37792982 1.69 ENSDART00000078828
ENSDART00000131342
ankyrin repeat and sterile alpha motif domain containing 3
chr1_+_50395721 1.68 ENSDART00000134065
dpy-30 histone methyltransferase complex regulatory subunit
chr10_+_9764591 1.67 ENSDART00000091780
ring finger and CCCH-type domains 2
chr22_-_26728956 1.66 ENSDART00000169887
wu:fu71h07
chr3_-_17881044 1.66 ENSDART00000013540
si:ch73-141c7.1
chr7_+_10346939 1.66

chr17_+_45430353 1.64 ENSDART00000162937
ezrin a
chr22_+_37696217 1.64 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr17_+_27383737 1.64 ENSDART00000156756
ENSDARG00000097369
chr7_+_39116005 1.62 ENSDART00000146702
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr22_-_13325475 1.62 ENSDART00000154095
si:ch211-227m13.1
chr22_+_28496424 1.60 ENSDART00000089546
ABI family, member 3 (NESH) binding protein b
chr3_+_21059221 1.60 ENSDART00000078807
zgc:123295
chr6_-_39656043 1.58 ENSDART00000155859
La ribonucleoprotein domain family, member 4Ab
chr11_-_39864543 1.58 ENSDART00000165781
family with sequence similarity 83, member E
chr4_-_376986 1.58 ENSDART00000067482
ENSDART00000160718
dynein, light chain, Tctex-type 1
chr21_-_35646193 1.57

chr4_+_13569588 1.56 ENSDART00000136152
calumenin a
chr24_+_18154733 1.54 ENSDART00000140994
thiamin pyrophosphokinase 1
chr3_+_49166063 1.53 ENSDART00000156347
epsin 3a
chr9_+_36316158 1.52 ENSDART00000176763
low density lipoprotein receptor-related protein 1Bb
chr7_+_16615075 1.51

chr2_+_19587617 1.50 ENSDART00000166292
coiled-coil and C2 domain containing 1B
chr21_+_9483423 1.49 ENSDART00000162834
mitogen-activated protein kinase 10
chr1_+_13386937 1.49 ENSDART00000021693
ankyrin 2a, neuronal
chr24_+_14093524 1.49

chr20_+_29307142 1.49 ENSDART00000153016
katanin p80 subunit B-like 1
chr11_-_25181234 1.49 ENSDART00000013714
GATA binding protein 1a
chr5_+_26925392 1.48 ENSDART00000051491
secreted frizzled-related protein 1a
chr2_+_52473102 1.47 ENSDART00000146418
Src homology 2 domain containing transforming protein D, a
chr24_+_26922969 1.46

chr8_-_50299273 1.41 ENSDART00000023639
NK2 transcription factor related 7
chr5_-_18548689 1.41 ENSDART00000137802
family with sequence similarity 214, member B
chr13_-_11553609 1.40

chr7_+_72128846 1.40 ENSDART00000123887
mitogen-activated protein kinase 8 interacting protein 1
chr2_+_25622497 1.39 ENSDART00000131977
protein phosphatase 2, regulatory subunit B'', alpha
chr21_+_45780315 1.38

chr18_+_29178482 1.38 ENSDART00000137587
ENSDART00000144423
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr20_+_29307039 1.37 ENSDART00000152949
katanin p80 subunit B-like 1
chr24_+_30343687 1.36 ENSDART00000162377
ENSDARG00000100270
chr3_-_28120668 1.34

chr16_-_21981065 1.33 ENSDART00000078858
si:ch73-86n18.1
chr2_-_26987186 1.33 ENSDART00000132854
U2 snRNP-associated SURP domain containing
chr20_-_1293519 1.32 ENSDART00000152436
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_+_18610282 1.31 ENSDART00000129970
si:dkeyp-118a3.2
chr11_+_18020191 1.29 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr19_-_7235125 1.28

chr18_+_14369543 1.28

chr6_-_120376 1.26 ENSDART00000148974
kelch-like ECH-associated protein 1b
chr16_-_19154920 1.26 ENSDART00000088818
formin homology 2 domain containing 3b
chr22_-_4622401 1.25 ENSDART00000106166
retinal homeobox gene 1
chr15_-_19186046 1.25 ENSDART00000108818
Rho GTPase activating protein 32a
chr10_-_28474085 1.24

chr24_-_1308951 1.24

chr23_+_14461509 1.24 ENSDART00000143618
baculoviral IAP repeat containing 7
chr1_+_15827083 1.22

chr18_+_45564871 1.21

chr6_-_39655998 1.19 ENSDART00000155859
La ribonucleoprotein domain family, member 4Ab
chr3_-_30027552 1.19 ENSDART00000103502
si:ch211-152f23.5
chr24_+_16760759 1.18 ENSDART00000066760
chaperonin containing TCP1, subunit 5 (epsilon)
chr6_+_12619062 1.17 ENSDART00000156341
family with sequence similarity 117, member Ba
chr16_+_13964949 1.17 ENSDART00000143983
zgc:174888
chr3_-_12818954 1.17 ENSDART00000158747
ENSDART00000158815
platelet-derived growth factor alpha polypeptide b
chr23_+_5632124 1.17 ENSDART00000059307
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr1_-_39509011 1.14 ENSDART00000146680
ENSDARG00000078251
chr25_-_15117843 1.14 ENSDART00000031499
wilms tumor 1a
chr24_-_37793048 1.14 ENSDART00000078828
ENSDART00000131342
ankyrin repeat and sterile alpha motif domain containing 3
chr12_+_35912088 1.12 ENSDART00000167873
BAI1-associated protein 2b
chr18_+_22228682 1.12 ENSDART00000165464
family with sequence similarity 65, member A
chr24_+_27469268 1.11 ENSDART00000105774
eph-like kinase 1
chr19_-_10962536 1.10 ENSDART00000160438
proteasome 26S subunit, non-ATPase 4a
chr5_-_44243476 1.10 ENSDART00000161408
fructose-1,6-bisphosphatase 1a
chr22_-_16971035 1.10 ENSDART00000090237
nuclear factor I/A
chr5_-_20527105 1.09 ENSDART00000133461
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr12_-_31342432 1.09 ENSDART00000148603
acyl-CoA synthetase long-chain family member 5
chr25_-_36886647 1.09 ENSDART00000160688
proteasome subunit alpha 1
chr7_+_620117 1.08 ENSDART00000152224
zgc:63470
chr17_-_14956738 1.08

chr2_-_25306278 1.08 ENSDART00000132050
helicase-like transcription factor
chr24_+_19842162 1.07 ENSDART00000123031
ENSDARG00000094073
chr5_-_18548376 1.05 ENSDART00000133330
family with sequence similarity 214, member B
chr12_-_28671833 1.05

chr19_-_10324632 1.05 ENSDART00000148073
shisa family member 7
chr4_-_72146177 1.04 ENSDART00000150546
si:dkey-262g12.3
chr20_+_18762031 1.04 ENSDART00000152136
ENSDART00000126959
tumor necrosis factor, alpha-induced protein 2a
chr3_-_28120255 1.03

chr4_-_885413 1.03 ENSDART00000022668
crystallin beta-gamma domain containing 1b
chr17_-_35011682 1.02

chr2_+_50892294 1.02 ENSDART00000018150
ENSDART00000111135
neuronal differentiation 6b
chr9_-_12063411 1.02 ENSDART00000038651
zinc finger protein 804A
chr17_+_48041768 1.00 ENSDART00000160219
solute carrier family 39, member 9
chr3_+_45345181 0.98

chr22_-_31110564 0.97 ENSDART00000022445
cullin-associated and neddylation-dissociated 2 (putative)
chr17_-_12812747 0.96 ENSDART00000022874
ENSDART00000046025
proteasome subunit alpha 6a
chr6_+_31377287 0.96

chr23_+_24999817 0.95 ENSDART00000137486
kelch-like family member 21
chr7_-_50642150 0.95 ENSDART00000022918
ankyrin repeat domain 46b
chr2_-_4277516 0.95

chr16_-_19385441 0.94 ENSDART00000118132
5S ribosomal RNA
chr14_-_25154966 0.94 ENSDART00000148652
solute carrier family 26 (anion exchanger), member 2
chr10_+_16267331 0.93 ENSDART00000129844
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr6_-_39312306 0.93

chr16_-_16614023 0.93 ENSDART00000160602
neurobeachin-like 2
chr12_+_23302859 0.92 ENSDART00000077732
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
1.7 5.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.2 3.5 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.5 1.5 GO:0042357 thiamine metabolic process(GO:0006772) thiamine diphosphate metabolic process(GO:0042357) thiamine-containing compound metabolic process(GO:0042723)
0.5 1.8 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.4 2.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.4 2.7 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.4 1.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.4 1.5 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.4 1.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.4 4.5 GO:0061337 cardiac conduction(GO:0061337)
0.4 1.5 GO:0030224 monocyte differentiation(GO:0030224)
0.4 2.6 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.4 1.1 GO:0015911 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 2.4 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.3 1.7 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.3 1.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.3 3.0 GO:0014896 regulation of muscle hypertrophy(GO:0014743) muscle hypertrophy(GO:0014896)
0.3 1.0 GO:0010265 SCF complex assembly(GO:0010265)
0.3 4.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 1.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 5.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.3 3.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.3 2.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.3 1.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 8.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 2.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.2 2.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 1.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 2.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.2 2.2 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.2 1.8 GO:0034333 adherens junction assembly(GO:0034333)
0.2 2.0 GO:0042026 protein refolding(GO:0042026)
0.2 1.4 GO:0003207 cardiac chamber formation(GO:0003207)
0.2 1.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 1.0 GO:0051601 exocyst localization(GO:0051601)
0.2 2.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 0.5 GO:2000391 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.2 1.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.1 2.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.7 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 2.1 GO:0006825 copper ion transport(GO:0006825)
0.1 2.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 2.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 3.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 0.9 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.9 GO:0008272 sulfate transport(GO:0008272)
0.1 1.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.9 GO:0032543 mitochondrial translation(GO:0032543)
0.1 0.5 GO:0031033 myosin filament organization(GO:0031033)
0.1 0.9 GO:0030168 platelet activation(GO:0030168)
0.1 0.4 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.2 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 1.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 3.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0021703 locus ceruleus development(GO:0021703)
0.1 1.8 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 4.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 2.5 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 1.5 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 1.7 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 2.2 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 4.0 GO:0050770 regulation of axonogenesis(GO:0050770)
0.0 2.4 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 2.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.7 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.6 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 1.7 GO:0045333 cellular respiration(GO:0045333)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 3.4 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 3.2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 1.4 GO:0001947 heart looping(GO:0001947)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0070062 extracellular exosome(GO:0070062)
0.3 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 2.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 2.0 GO:0016234 inclusion body(GO:0016234)
0.3 1.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 2.4 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.2 GO:0001650 fibrillar center(GO:0001650)
0.2 8.0 GO:0030426 growth cone(GO:0030426)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 2.4 GO:0031594 neuromuscular junction(GO:0031594)
0.2 1.8 GO:0031430 M band(GO:0031430)
0.2 4.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:0032420 stereocilium(GO:0032420)
0.1 1.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 2.2 GO:0030057 desmosome(GO:0030057)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 4.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 1.0 GO:0000145 exocyst(GO:0000145)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.1 GO:0031941 filamentous actin(GO:0031941)
0.1 3.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 4.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 5.8 GO:0030424 axon(GO:0030424)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 4.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 2.2 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.7 5.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
1.0 2.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.8 7.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.7 2.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.6 2.6 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.6 3.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 1.7 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.6 5.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.4 2.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.4 1.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 2.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.3 2.4 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.3 3.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.3 5.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 2.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 1.7 GO:0048039 ubiquinone binding(GO:0048039)
0.3 1.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 3.2 GO:0005080 protein kinase C binding(GO:0005080)
0.2 2.1 GO:0016531 copper chaperone activity(GO:0016531)
0.2 2.4 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.5 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.7 GO:0046332 SMAD binding(GO:0046332)
0.1 1.1 GO:0019203 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.1 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 1.8 GO:0017069 snRNA binding(GO:0017069)
0.0 2.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 2.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 3.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 4.9 GO:0015631 tubulin binding(GO:0015631)
0.0 4.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 8.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.0 GO:0004044 amidophosphoribosyltransferase activity(GO:0004044)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0000149 SNARE binding(GO:0000149)
0.0 4.3 GO:0005525 GTP binding(GO:0005525)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.5 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.5 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 5.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 2.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing