Project

DANIO-CODE

Navigation
Downloads

Results for mecp2

Z-value: 1.65

Motif logo

Transcription factors associated with mecp2

Gene Symbol Gene ID Gene Info
ENSDARG00000014218 methyl CpG binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecp2dr10_dc_chr8_-_7618945_7619005-0.019.6e-01Click!

Activity profile of mecp2 motif

Sorted Z-values of mecp2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mecp2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
KN149861v1_-_8998 2.85

chr1_-_54570813 2.15 ENSDART00000098615
nanos homolog 3
chr4_-_12931110 2.01 ENSDART00000013604
LEM domain containing 3
chr25_+_34627031 1.94 ENSDART00000154377
histone cluster 1 H2B family member a
chr25_+_34549177 1.86 ENSDART00000157206
ENSDARG00000089719
chr7_-_73628151 1.60 ENSDART00000123136
Histone H2B 1/2
chr19_-_28247275 1.56

chr11_+_42265857 1.42 ENSDART00000039206
ribosomal protein S23
chr7_+_73595871 1.37 ENSDART00000169756
Histone H2B 1/2
chr18_+_18011562 1.34 ENSDART00000005027
ENSDARG00000011498
chr4_-_66538843 1.34 ENSDART00000165173
ENSDARG00000103357
chr1_-_54294382 1.31 ENSDART00000038330
KH-type splicing regulatory protein
KN150531v1_-_8098 1.28 ENSDART00000177246
ENSDARG00000106081
chr19_+_43468369 1.28 ENSDART00000165202
pumilio RNA-binding family member 1
chr7_+_5839103 1.26 ENSDART00000145370
zgc:112234
chr17_+_48914379 1.25

chr4_-_12930797 1.20 ENSDART00000108552
LEM domain containing 3
KN149861v1_-_8662 1.19 ENSDART00000179340
ENSDARG00000107716
chr13_+_2345595 1.18

chr16_+_11351423 1.18 ENSDART00000138335
glycogen synthase kinase 3 alpha b
chr12_-_49212400 1.15 ENSDART00000112479
acyl-CoA dehydrogenase, short/branched chain
chr7_-_10318692 1.15 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr19_+_14592632 1.13 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr20_+_32620786 1.12 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr3_-_7769397 1.09

chr5_-_29782745 1.08 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr18_+_25016753 1.08 ENSDART00000099476
family with sequence similarity 174, member B
chr15_-_47307539 1.05 ENSDART00000027060
DM1 locus, WD repeat containing
chr11_-_21203166 1.04 ENSDART00000080051
Ras association domain family member 5
chr7_+_41607231 1.03 ENSDART00000165789
ENSDART00000115090
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr2_-_38305602 1.00 ENSDART00000061677
si:ch211-14a17.6
chr1_-_22617455 0.99 ENSDART00000137567
small integral membrane protein 14
chr25_+_4454862 0.98 ENSDART00000110598
zmp:0000001167
chr22_-_20141216 0.97 ENSDART00000128023
BTB (POZ) domain containing 2a
chr4_-_66543241 0.95

chr19_+_48144910 0.95 ENSDART00000149705
cell division cycle associated 8
chr5_-_50972186 0.94 ENSDART00000134606
orthopedia homeobox b
chr2_+_10175869 0.93 ENSDART00000153323
ENSDART00000043499
SEC22 homolog B, vesicle trafficking protein a
chr16_+_33999554 0.91 ENSDART00000159969
AT rich interactive domain 1Aa (SWI-like)
chr2_+_27835370 0.91 ENSDART00000078305
zinc finger, SWIM-type containing 5
chr7_-_73590802 0.89 ENSDART00000167855
Histone H2B 1/2
chr3_+_11985816 0.86 ENSDART00000081367
DnaJ (Hsp40) homolog, subfamily A, member 3A
chr16_+_33999263 0.85 ENSDART00000164447
AT rich interactive domain 1Aa (SWI-like)
chr24_-_1014256 0.85 ENSDART00000114544
cyclin-dependent kinase 13
chr21_+_11683704 0.85 ENSDART00000081646
glutaredoxin (thioltransferase)
chr19_+_43468926 0.84

chr21_+_11685911 0.84 ENSDART00000031786
glutaredoxin (thioltransferase)
chr25_+_34562216 0.83 ENSDART00000154655
ENSDARG00000092743
chr22_-_20141589 0.83 ENSDART00000085913
BTB (POZ) domain containing 2a
chr22_-_29695242 0.82

chr25_-_9889107 0.82 ENSDART00000137407
ENSDARG00000093575
chr12_-_17370920 0.81 ENSDART00000130735
multiple inositol-polyphosphate phosphatase 1b
chr11_-_27670402 0.81 ENSDART00000173219
eukaryotic translation initiation factor 4 gamma, 3a
chr25_-_13307171 0.81 ENSDART00000056723
GINS complex subunit 3
chr15_+_38397772 0.81 ENSDART00000142403
si:dkey-24p1.6
chr22_+_132285 0.80 ENSDART00000059140
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr21_+_4091665 0.77 ENSDART00000148138
leucine rich repeat containing 8 family, member Aa
chr8_-_22265875 0.76 ENSDART00000134033
si:ch211-147a11.3
chr16_+_42567707 0.75 ENSDART00000166640
si:ch211-215k15.5
chr7_-_41601001 0.75 ENSDART00000174258
zgc:92818
chr5_-_40503137 0.74 ENSDART00000051070
golgi phosphoprotein 3
chr24_+_12689711 0.74 ENSDART00000114762
nanog homeobox
chr16_+_33999719 0.73 ENSDART00000159969
AT rich interactive domain 1Aa (SWI-like)
chr11_-_21203114 0.71 ENSDART00000080051
Ras association domain family member 5
chr1_-_53021646 0.71

chr12_-_13692190 0.70 ENSDART00000152370
forkhead box H1
chr21_+_11686037 0.70 ENSDART00000031786
glutaredoxin (thioltransferase)
chr8_-_4270732 0.69 ENSDART00000134378
cut-like homeobox 2b
chr19_+_14490203 0.69 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr19_-_3785774 0.69 ENSDART00000161738
small integral membrane protein 13
chr11_-_44756789 0.69 ENSDART00000161712
synaptogyrin 2b
chr14_-_47210912 0.68 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr15_-_30935719 0.68 ENSDART00000050649
musashi RNA-binding protein 2b
chr10_-_25383262 0.68 ENSDART00000166348
chaperonin containing TCP1, subunit 8 (theta)
chr24_+_12689887 0.68 ENSDART00000114762
nanog homeobox
chr23_-_27768575 0.67 ENSDART00000146703
IKAROS family zinc finger 4
chr21_+_13136338 0.67 ENSDART00000142569
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr19_+_14490375 0.67 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr5_-_8712114 0.66 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr21_+_45622590 0.66 ENSDART00000162422
secretion associated, Ras related GTPase 1B
chr7_+_31750514 0.66 ENSDART00000173976
methyltransferase like 15
chr2_+_39142628 0.66 ENSDART00000179419
calsyntenin 2
chr15_-_34700453 0.65 ENSDART00000140882
isoprenoid synthase domain containing
chr21_+_11686197 0.64 ENSDART00000031786
glutaredoxin (thioltransferase)
chr16_-_42116471 0.63 ENSDART00000058620
zona pellucida glycoprotein 3d tandem duplicate 1
chr7_+_15479700 0.63

KN149861v1_-_6916 0.62 ENSDART00000169003
5.8S ribosomal RNA
chr16_-_23885481 0.62 ENSDART00000139964
ribosomal protein S27, isoform 2
chr5_-_13145749 0.61 ENSDART00000166957
purine-rich element binding protein Ba
chr23_+_540664 0.61 ENSDART00000034707
LSM family member 14B
chr23_+_41015697 0.61 ENSDART00000115161
RALBP1 associated Eps domain containing 2
chr17_-_49910160 0.60 ENSDART00000122747
transmembrane protein 30Aa
chr19_-_32313943 0.59 ENSDART00000113797
zinc finger and BTB domain containing 10
chr7_-_10318801 0.59 ENSDART00000172761
ENSDART00000170476
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr5_+_65491173 0.59 ENSDART00000050847
ENSDART00000172117
glycine decarboxylase
chr19_+_14132374 0.59 ENSDART00000164696
transmembrane protein 222b
chr19_-_42892975 0.58 ENSDART00000131715
proteasome subunit beta 4
KN149861v1_-_8062 0.58 ENSDART00000179340
ENSDARG00000107716
chr14_-_44880144 0.58 ENSDART00000163543
abhydrolase domain containing 18
chr10_-_35488523 0.57

chr17_-_23874694 0.57 ENSDART00000122108
PDZ domain containing 8
chr3_+_27476229 0.57 ENSDART00000024453
ubiquitin specific peptidase 7 (herpes virus-associated)
chr7_+_16096816 0.57 ENSDART00000002449
metallophosphoesterase domain containing 2a
chr1_-_54294205 0.57 ENSDART00000140016
KH-type splicing regulatory protein
chr19_+_14592518 0.56 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr10_-_2655016 0.56

KN149883v1_-_5164 0.56 ENSDART00000158506
ENSDART00000172360
NADH:ubiquinone oxidoreductase subunit A13
chr22_-_3165441 0.56 ENSDART00000158009
lon peptidase 1, mitochondrial
chr8_-_22265802 0.56 ENSDART00000134033
si:ch211-147a11.3
chr16_+_22949379 0.55 ENSDART00000137783
flavin adenine dinucleotide synthetase 1
chr22_+_26736632 0.55

chr23_-_24328931 0.55

chr19_+_770458 0.55 ENSDART00000062518
glutathione S-transferase rho
chr22_-_5722123 0.55

chr24_-_37810565 0.55 ENSDART00000172178
si:ch211-231f6.6
chr1_+_14572155 0.55 ENSDART00000033018
phosphatidylinositol 4-kinase type 2 beta
chr14_+_300285 0.55 ENSDART00000159949
WD repeat domain 1
chr17_-_23874858 0.54 ENSDART00000122108
PDZ domain containing 8
chr14_+_42109615 0.54

chr7_-_28771601 0.53 ENSDART00000052342
THAP domain containing 11
chr2_+_50327729 0.53 ENSDART00000097939
zinc finger, CCHC domain containing 2
chr19_+_41894734 0.52 ENSDART00000087187
argonaute RISC catalytic component 2
chr3_-_10615725 0.52 ENSDART00000048095
ENSDART00000155152
elaC ribonuclease Z 2
chr24_-_1014318 0.52 ENSDART00000114544
cyclin-dependent kinase 13
chr19_+_44185325 0.52 ENSDART00000063870
ribosomal protein L11
chr16_+_22949494 0.52 ENSDART00000137783
flavin adenine dinucleotide synthetase 1
chr2_+_38305772 0.52 ENSDART00000170672
neural precursor cell expressed, developmentally down-regulated 8, like
chr5_-_40503363 0.52 ENSDART00000074781
golgi phosphoprotein 3
chr25_-_19388415 0.52 ENSDART00000156016
zgc:193812
chr23_+_12426885 0.51 ENSDART00000143728
phosphatidylinositol glycan anchor biosynthesis, class T
chr19_+_41894906 0.51 ENSDART00000087187
argonaute RISC catalytic component 2
chr24_-_23973276 0.51 ENSDART00000111096
zgc:112982
KN149861v1_-_6089 0.51

chr8_-_22266041 0.50 ENSDART00000134033
si:ch211-147a11.3
chr20_+_54595334 0.50

chr19_+_1298795 0.49 ENSDART00000113368
ring finger protein 5
chr24_+_24140538 0.49 ENSDART00000122294
YTH N(6)-methyladenosine RNA binding protein 3
chr20_-_30132364 0.49 ENSDART00000033588
ENSDARG00000024870
chr9_-_32347822 0.49 ENSDART00000037182
ankyrin repeat domain 44
chr21_-_25576567 0.48 ENSDART00000115276
ENSDART00000137896
fibroblast growth factor (acidic) intracellular binding protein b
chr1_-_51870424 0.48 ENSDART00000135636
aspartoacylase (aminocyclase) 3, tandem duplicate 1
chr21_-_44707514 0.48 ENSDART00000013814
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr6_+_6640324 0.47 ENSDART00000150967
si:ch211-85n16.3
chr8_+_388003 0.47 ENSDART00000067668
PYM homolog 1, exon junction complex associated factor
chr14_-_6096258 0.47

chr17_-_6225136 0.46 ENSDART00000137389
ENSDART00000115389
taxilin beta b
chr10_+_3427790 0.46 ENSDART00000081599
protein tyrosine phosphatase, non-receptor type 11, a
chr10_+_43208682 0.46 ENSDART00000160159
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr20_+_32620937 0.46 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr23_-_27579257 0.46 ENSDART00000137229
ankyrin repeat and SOCS box containing 8
chr19_+_14592246 0.46 ENSDART00000161088
ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr2_-_9946238 0.45 ENSDART00000097732
dishevelled segment polarity protein 3a
chr7_-_51497945 0.45 ENSDART00000054591
bone morphogenetic protein 15
chr11_-_25615491 0.45 ENSDART00000145655
transmembrane protein 51b
chr18_+_5303006 0.45

chr2_-_9946148 0.45 ENSDART00000175460
dishevelled segment polarity protein 3a
chr23_+_20505319 0.45 ENSDART00000140219
solute carrier family 35 (GDP-fucose transporter), member C2
chr9_-_23431733 0.45 ENSDART00000053282
cyclin T2a
chr17_-_27217309 0.45 ENSDART00000130080
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr7_-_26260802 0.44 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr5_+_22173976 0.44 ENSDART00000142112
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr13_+_13875110 0.44 ENSDART00000131875
attractin
KN149861v1_-_6661 0.44

chr16_+_17762256 0.44 ENSDART00000128672
transmembrane protein 238b
chr19_-_3785709 0.44 ENSDART00000165947
ENSDARG00000099249
chr22_+_11114323 0.44 ENSDART00000047442
BCL6 corepressor
chr12_-_29928951 0.43 ENSDART00000149077
ENSDART00000148847
TruB pseudouridine (psi) synthase family member 1
chr8_-_4517590 0.43 ENSDART00000090731
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr21_+_8334453 0.43 ENSDART00000055336
DENN/MADD domain containing 1A
chr2_+_37855019 0.43 ENSDART00000113337
poly (ADP-ribose) polymerase 2
chr11_+_40847576 0.43 ENSDART00000041531
parkinson protein 7
chr20_-_45757288 0.43 ENSDART00000124582
ENSDART00000100290
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr18_-_46371631 0.43 ENSDART00000018163
interferon regulatory factor 2 binding protein 1
chr21_+_11685992 0.42 ENSDART00000031786
glutaredoxin (thioltransferase)
chr23_-_5188577 0.42 ENSDART00000123191
ubiquitin-conjugating enzyme E2T (putative)
chr18_+_19893842 0.42 ENSDART00000165336
zgc:162898
chr19_-_48144752 0.42 ENSDART00000158979
c19h1orf109 homolog (H. sapiens)
chr24_+_5176362 0.42 ENSDART00000155926
si:ch73-206p6.1
chr20_+_32620873 0.42 ENSDART00000147319
sex comb on midleg-like 4 (Drosophila)
chr7_-_30654776 0.42 ENSDART00000075421
sorbitol dehydrogenase
chr4_+_9910588 0.41 ENSDART00000159762
SET binding factor 1
chr17_+_52438099 0.41 ENSDART00000135246
dihydrolipoamide S-succinyltransferase
chr1_-_50626230 0.41

chr19_+_41895061 0.40 ENSDART00000087187
argonaute RISC catalytic component 2
chr23_+_540624 0.40 ENSDART00000034707
LSM family member 14B
chr21_-_13026036 0.40 ENSDART00000135623
family with sequence similarity 219, member Aa
KN150307v1_+_6450 0.40 ENSDART00000159959
ENSDARG00000098784
chr19_+_3115685 0.40 ENSDART00000127473
ENSDART00000126549
ENSDART00000024593
ENSDART00000082353
ENSDART00000141324
heat shock transcription factor 1
chr2_+_38305689 0.40 ENSDART00000170672
neural precursor cell expressed, developmentally down-regulated 8, like
chr2_-_37418967 0.40 ENSDART00000015723
protein kinase C, iota
chr20_-_9440244 0.39 ENSDART00000025330
retinol dehydrogenase 14b (all-trans/9-cis/11-cis)
chr9_+_331815 0.39 ENSDART00000170312
ARP5 actin related protein 5 homolog
chr7_-_6308104 0.39 ENSDART00000173010
zgc:112234
chr19_-_48144715 0.39 ENSDART00000158979
c19h1orf109 homolog (H. sapiens)
chr2_-_47766563 0.39 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr25_-_29914405 0.39 ENSDART00000171137
protein disulfide isomerase family A, member 3
chr9_-_32532843 0.39 ENSDART00000078499
raftlin family member 2
chr25_-_13562597 0.39 ENSDART00000045488
casein kinase 2, alpha prime polypeptide b
chr25_+_35793115 0.39 ENSDART00000103007
zgc:173552
chr20_-_48255596 0.38 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0043622 cortical microtubule organization(GO:0043622)
0.4 1.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.4 2.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.4 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.2 3.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 1.7 GO:0035999 folic acid-containing compound biosynthetic process(GO:0009396) tetrahydrofolate interconversion(GO:0035999)
0.2 0.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 0.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 0.7 GO:0070861 regulation of COPII vesicle coating(GO:0003400) regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.2 0.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.2 0.6 GO:0030728 ovulation(GO:0030728)
0.2 0.5 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.2 0.5 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.1 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.1 0.7 GO:0010159 specification of organ position(GO:0010159)
0.1 0.5 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.9 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.4 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 1.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.3 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.6 GO:2000344 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0046078 dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078)
0.1 0.4 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 2.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 2.1 GO:0019827 stem cell population maintenance(GO:0019827)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.5 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:2000737 negative regulation of stem cell differentiation(GO:2000737)
0.1 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.2 GO:1903010 regulation of bone development(GO:1903010)
0.1 1.1 GO:0045116 protein neddylation(GO:0045116)
0.1 0.9 GO:0021884 forebrain neuron development(GO:0021884)
0.1 3.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.2 GO:0043420 anthranilate metabolic process(GO:0043420)
0.1 0.4 GO:0019405 alditol catabolic process(GO:0019405)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.7 GO:0009408 response to heat(GO:0009408)
0.1 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 1.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.2 GO:0097192 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.4 GO:0032447 protein urmylation(GO:0032447)
0.0 0.5 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.4 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0034033 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.5 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:1990709 presynaptic active zone organization(GO:1990709)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.6 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0030534 adult behavior(GO:0030534)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.4 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.2 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 1.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0090382 phagosome maturation(GO:0090382)
0.0 1.1 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390) ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.9 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.5 GO:0060119 inner ear receptor cell development(GO:0060119)
0.0 0.3 GO:0050821 protein stabilization(GO:0050821)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0035060 brahma complex(GO:0035060)
0.3 3.2 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.2 1.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.2 2.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.2 0.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 2.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.1 0.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 2.1 GO:0043186 P granule(GO:0043186)
0.1 0.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.3 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.7 GO:0005921 gap junction(GO:0005921)
0.1 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.5 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 1.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0016882 cyclo-ligase activity(GO:0016882)
0.4 2.1 GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA(GO:0070551)
0.4 1.2 GO:0034417 bisphosphoglycerate 3-phosphatase activity(GO:0034417)
0.3 1.4 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.2 1.9 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.6 GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424)
0.2 0.5 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.2 0.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 0.5 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 3.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 1.6 GO:0032190 acrosin binding(GO:0032190)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.5 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.5 GO:0031386 protein tag(GO:0031386)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0004352 glutamate dehydrogenase (NAD+) activity(GO:0004352) glutamate dehydrogenase [NAD(P)+] activity(GO:0004353) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 2.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 2.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 3.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 1.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.2 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 1.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.8 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.5 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.9 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.5 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation