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Results for mef2aa

Z-value: 2.55

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Transcription factors associated with mef2aa

Gene Symbol Gene ID Gene Info
mef2aa
ENSDARG00000031756 myocyte enhancer factor 2aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2aadr10_dc_chr18_+_23198330_231983520.962.0e-09Click!

Activity profile of mef2aa motif

Sorted Z-values of mef2aa motif

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2aa

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_60973097 10.23 ENSDART00000055062
pvalb1
parvalbumin 1
chr17_-_124685 9.64 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr1_-_12584282 9.22 ENSDART00000127838
pcdh18a
protocadherin 18a
chr3_-_32686790 8.67 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr7_+_6814828 8.64 ENSDART00000001649
actn3b
actinin alpha 3b
chr12_-_17590507 8.04 ENSDART00000010144
pvalb2
parvalbumin 2
chr19_+_2162466 7.44

chr12_-_5085227 7.05 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr19_-_7531709 6.98 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr1_-_12584179 6.86

chr1_+_6862901 6.86 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr2_-_28446615 6.82 ENSDART00000179495
cdh6
cadherin 6
chr5_-_71340996 6.82 ENSDART00000162526
smyd1a
SET and MYND domain containing 1a
chr3_+_28808901 6.28 ENSDART00000141904
ENSDART00000077221
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr5_+_38236956 5.82 ENSDART00000160236
fras1
Fraser extracellular matrix complex subunit 1
chr5_-_28090077 5.74

chr1_-_50066633 5.41

chr15_+_7068253 5.40 ENSDART00000114560
pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr5_+_66712197 5.38 ENSDART00000014822
ebf2
early B-cell factor 2
chr12_+_25684420 5.33 ENSDART00000024415
epas1a
endothelial PAS domain protein 1a
chr8_-_11191783 5.31 ENSDART00000131171
unc45b
unc-45 myosin chaperone B
chr1_+_16683931 5.29 ENSDART00000103262
ENSDART00000145068
ENSDART00000169619
ENSDART00000010526
fat1a
FAT atypical cadherin 1a
chr23_+_20183765 5.29 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr12_-_25973094 5.24 ENSDART00000171206
ENSDART00000171212
ENSDART00000170265
ldb3b
LIM domain binding 3b
chr16_+_5466342 5.24 ENSDART00000160008
plecb
plectin b
chr12_+_6007990 5.21 ENSDART00000091868
g6pca.2
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr15_+_24064257 5.15 ENSDART00000156714
CR394545.1
ENSDARG00000097097
chr22_-_6977038 5.07 ENSDART00000133143
ENSDART00000146813
gpd1b
glycerol-3-phosphate dehydrogenase 1b
chr14_+_21816442 4.98 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr7_-_22685672 4.97 ENSDART00000101447
tnfsf10l
TNF superfamily member 10, like
chr1_-_10391257 4.92 ENSDART00000102903
dmd
dystrophin
chr8_-_17480730 4.78 ENSDART00000100667
skia
v-ski avian sarcoma viral oncogene homolog a
chr18_-_26483645 4.66

chr3_+_34064081 4.55

chr10_-_8074713 4.50 ENSDART00000140476
atp6v0a2a
ATPase, H+ transporting, lysosomal V0 subunit a2a
chr16_-_29229687 4.50 ENSDART00000132589
mef2d
myocyte enhancer factor 2d
chr20_+_15653121 4.41 ENSDART00000152702
jun
jun proto-oncogene
chr1_-_30772653 4.37 ENSDART00000087115
rims1b
regulating synaptic membrane exocytosis 1b
chr3_-_39031305 4.24 ENSDART00000022393
si:dkeyp-57f11.2
si:dkeyp-57f11.2
chr24_+_26922969 4.22

chr8_+_33010788 4.04 ENSDART00000172672
angptl2b
angiopoietin-like 2b
chr8_+_10267246 3.99 ENSDART00000159312
ENSDART00000160766
pim1
Pim-1 proto-oncogene, serine/threonine kinase
chr7_+_59344089 3.91 ENSDART00000146384
rpl34
ribosomal protein L34
chr15_+_19717045 3.83 ENSDART00000138680
lim2.3
lens intrinsic membrane protein 2.3
chr7_-_23474701 3.79 ENSDART00000048050
ITGB1BP2
integrin subunit beta 1 binding protein 2
chr15_-_27778111 3.74 ENSDART00000134373
lhx1a
LIM homeobox 1a
chr2_+_22839514 3.71 ENSDART00000167915
lrrc8da
leucine rich repeat containing 8 family, member Da
KN150214v1_-_155944 3.71

chr15_+_7068009 3.70 ENSDART00000155268
pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr24_+_19842162 3.69 ENSDART00000123031
CR381686.3
ENSDARG00000094073
chr14_-_29542922 3.68

chr1_+_51706536 3.61

chr17_-_14663139 3.60 ENSDART00000037371
ppp1r13ba
protein phosphatase 1, regulatory subunit 13Ba
chr23_+_17856053 3.58 ENSDART00000154427
CR381647.1
ENSDARG00000097211
chr13_+_24703802 3.57 ENSDART00000101274
zgc:153981
zgc:153981
chr16_-_31517906 3.57 ENSDART00000145691
ENSDARG00000054814
ENSDARG00000054814
chr23_-_39956151 3.52 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr10_+_36710393 3.47

chr13_+_22350043 3.42 ENSDART00000136863
ldb3a
LIM domain binding 3a
chr17_-_14551031 3.41 ENSDART00000162452
daam1a
dishevelled associated activator of morphogenesis 1a
chr15_+_9351511 3.32 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr25_-_22821132 3.30

chr14_-_26999410 3.25 ENSDART00000159727
pcdh11
protocadherin 11
chr18_+_26737365 3.19 ENSDART00000141672
alpk3a
alpha-kinase 3a
chr24_-_25545773 3.18 ENSDART00000015391
chrnd
cholinergic receptor, nicotinic, delta (muscle)
chr1_-_5796394 3.14 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr19_+_25892125 3.12 ENSDART00000112808
col28a1a
collagen, type XXVIII, alpha 1a
chr5_+_23802054 3.09 ENSDART00000144226
ctsll
cathepsin L, like
chr18_+_23204736 3.05 ENSDART00000171594
ENSDART00000148106
mef2aa
myocyte enhancer factor 2aa
chr10_-_22875997 3.04 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr5_+_69036145 3.00 ENSDART00000174403
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr13_+_23065500 2.97 ENSDART00000158370
sorbs1
sorbin and SH3 domain containing 1
chr6_-_12224562 2.95 ENSDART00000090266
ENSDART00000144028
gpd2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr18_-_36291570 2.92

chr14_+_23220869 2.88 ENSDART00000112930
si:ch211-221f10.2
si:ch211-221f10.2
chr9_-_22371512 2.79 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr19_+_5375413 2.75 ENSDART00000141237
si:dkeyp-113d7.10
si:dkeyp-113d7.10
chr15_+_5935952 2.71 ENSDART00000152520
ENSDART00000145827
sh3bgr
SH3 domain binding glutamate-rich protein
chr24_-_3334678 2.71

chr11_-_38940966 2.71 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr7_-_29300402 2.70 ENSDART00000099477
rorab
RAR-related orphan receptor A, paralog b
chr23_+_24999817 2.70 ENSDART00000137486
klhl21
kelch-like family member 21
chr4_+_6024067 2.70

chr3_+_28450576 2.69 ENSDART00000150893
sept12
septin 12
chr13_-_2083873 2.67 ENSDART00000129773
mlip
muscular LMNA-interacting protein
chr7_+_38735582 2.65 ENSDART00000173735
dgkza
diacylglycerol kinase, zeta a
chr5_+_51201924 2.65 ENSDART00000087467
cmya5
cardiomyopathy associated 5
chr3_-_52419408 2.63 ENSDART00000154260
si:dkey-210j14.4
si:dkey-210j14.4
chr24_-_6617860 2.60 ENSDART00000166216
arhgap21a
Rho GTPase activating protein 21a
chr16_-_13914368 2.56

chr16_-_28943421 2.53 ENSDART00000149501
si:dkey-239n17.4
si:dkey-239n17.4
chr15_-_25581628 2.52

chr19_-_7531649 2.51 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr12_+_23717554 2.48 ENSDART00000152997
svila
supervillin a
chr16_-_30816954 2.43 ENSDART00000129594
ptk2ab
protein tyrosine kinase 2ab
chr17_+_8874210 2.41

chr3_+_40028301 2.41 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr15_-_7327976 2.40

chr3_+_32394550 2.39 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr5_-_57016269 2.39 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr25_-_18044103 2.38 ENSDART00000113581
kitlga
kit ligand a
chr3_-_5318289 2.37 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr3_+_28822408 2.36 ENSDART00000133528
lgals2a
lectin, galactoside-binding, soluble, 2a
chr18_+_40364675 2.36 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr23_+_17856104 2.35 ENSDART00000154427
CR381647.1
ENSDARG00000097211
chr7_-_29300448 2.33 ENSDART00000019140
rorab
RAR-related orphan receptor A, paralog b
chr24_+_25326286 2.31 ENSDART00000066625
smpx
small muscle protein, X-linked
chr1_-_21987718 2.30 ENSDART00000128918
fgfbp1b
fibroblast growth factor binding protein 1b
chr16_+_24766043 2.29 ENSDART00000114304
ywhabl
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr3_+_31821397 2.29 ENSDART00000148861
kcnc3a
potassium voltage-gated channel, Shaw-related subfamily, member 3a
chr21_-_5692160 2.28 ENSDART00000075137
ENSDART00000151202
ccni
cyclin I
chr3_+_24587720 2.27

chr5_-_63912916 2.25

chr23_-_20026717 2.21 ENSDART00000153828
atp2b3b
ATPase, Ca++ transporting, plasma membrane 3b
chr2_-_3846844 2.19 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr20_-_36672566 2.17 ENSDART00000062893
enah
enabled homolog (Drosophila)
chr11_+_18020191 2.14 ENSDART00000125984
mustn1b
musculoskeletal, embryonic nuclear protein 1b
chr23_-_18958008 2.14 ENSDART00000133419
CR847953.1
ENSDARG00000057403
chr7_-_22685631 2.14 ENSDART00000122113
tnfsf10l
TNF superfamily member 10, like
chr7_+_15629256 2.10 ENSDART00000138689
ENSDART00000137235
pax6b
paired box 6b
chr21_+_20347283 2.04 ENSDART00000026430
hspb11
heat shock protein, alpha-crystallin-related, b11
chr3_+_22774002 2.04

chr1_-_40557436 2.03 ENSDART00000144424
rgs12b
regulator of G protein signaling 12b
chr2_-_6351592 2.02

chr5_+_36677034 2.02 ENSDART00000159402
si:dkey-17o15.2
si:dkey-17o15.2
chr8_-_50270783 2.00 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr24_+_25326233 1.99 ENSDART00000066625
smpx
small muscle protein, X-linked
chr6_-_52234513 1.94 ENSDART00000133554
tomm34
translocase of outer mitochondrial membrane 34
chr1_+_5474009 1.92 ENSDART00000136060
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr23_-_28286971 1.91

chr9_-_28588288 1.89 ENSDART00000104317
ENSDART00000064343
klf7b
Kruppel-like factor 7b
chr12_+_5969088 1.88 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr5_-_22847399 1.87 ENSDART00000169258
nlgn3b
neuroligin 3b
chr1_-_54532919 1.82 ENSDART00000111671
mri1
methylthioribose-1-phosphate isomerase 1
KN150425v1_+_103569 1.81 ENSDART00000169530
cyp1c1
cytochrome P450, family 1, subfamily C, polypeptide 1
chr10_-_37098396 1.81 ENSDART00000155277
BX323076.2
ENSDARG00000097288
chr23_+_44137593 1.80 ENSDART00000148470
CU993818.1
ENSDARG00000095873
chr10_-_17274395 1.79 ENSDART00000135679
rab36
RAB36, member RAS oncogene family
chr10_-_24401876 1.78 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr21_+_11592175 1.77 ENSDART00000147473
pcsk1
proprotein convertase subtilisin/kexin type 1
chr14_-_32838287 1.76

chr15_-_25581590 1.73

chr17_-_5426195 1.72 ENSDART00000035944
clic5a
chloride intracellular channel 5a
chr25_-_23648033 1.70 ENSDART00000089278
si:ch211-236l14.4
si:ch211-236l14.4
chr21_+_13031158 1.69 ENSDART00000081426
odf2a
outer dense fiber of sperm tails 2a
chr13_+_18130206 1.69

chr20_-_2075861 1.68 ENSDART00000113237
ARHGAP18
Rho GTPase activating protein 18
chr21_-_32449627 1.68

chr20_-_26102193 1.65 ENSDART00000136518
capn3b
calpain 3b
chr20_-_26102273 1.64 ENSDART00000063177
capn3b
calpain 3b
chr5_-_56965438 1.63 ENSDART00000074306
hspb2
heat shock protein, alpha-crystallin-related, b2
chr20_-_37673852 1.62

chr3_-_42275696 1.61 ENSDART00000167844
mafk
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr20_+_6640497 1.61 ENSDART00000138361
tns3.2
tensin 3, tandem duplicate 2
chr20_-_48255596 1.59 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr9_-_43072092 1.58 ENSDART00000125953
ttn.1
titin, tandem duplicate 1
chr25_+_33924376 1.53

chr6_-_31268267 1.42

chr2_-_16586136 1.40 ENSDART00000133708
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr24_-_32115473 1.38 ENSDART00000168419
rsu1
Ras suppressor protein 1
chr3_+_32272097 1.38 ENSDART00000156982
si:ch211-195b15.8
si:ch211-195b15.8
chr2_-_24113073 1.38 ENSDART00000148685
xirp1
xin actin binding repeat containing 1
chr13_+_18130077 1.35

chr22_-_37676556 1.35 ENSDART00000028085
ttc14
tetratricopeptide repeat domain 14
chr6_+_42478185 1.33 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr14_+_14541725 1.33 ENSDART00000169932
ccdc142
coiled-coil domain containing 142
chr5_-_63912962 1.32

chr20_+_19879839 1.32 ENSDART00000132576
BX510657.1
ENSDARG00000093899
chr16_+_34157866 1.30 ENSDART00000140552
tcea3
transcription elongation factor A (SII), 3
chr6_+_27348529 1.30

chr8_-_46903869 1.30 ENSDART00000161462
acot7
acyl-CoA thioesterase 7
chr2_-_19532470 1.29 ENSDART00000166881
BX323588.1
ENSDARG00000102520
chr2_-_10300329 1.27 ENSDART00000138081
bcl6ab
B-cell CLL/lymphoma 6a, genome duplicate b
chr3_+_29314649 1.25 ENSDART00000020381
grap2a
GRB2-related adaptor protein 2a
chr9_-_24220466 1.23 ENSDART00000021218
rpe
ribulose-5-phosphate-3-epimerase
chr19_+_15666408 1.22 ENSDART00000131134
si:ch211-206a7.2
si:ch211-206a7.2
chr6_-_18814348 1.21 ENSDART00000115118
tns1a
tensin 1a
chr24_+_20815964 1.20 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr20_-_16553010 1.18

chr18_-_33072423 1.17 ENSDART00000177619
CU929403.2
ENSDARG00000106481
chr1_-_54319671 1.16 ENSDART00000074058
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr7_-_18751216 1.16 ENSDART00000157618
HACD4
3-hydroxyacyl-CoA dehydratase 4
chr7_+_57374714 1.15 ENSDART00000110623
arsj
arylsulfatase family, member J
chr7_-_29861232 1.14

chr13_-_30807799 1.12

chr3_-_49010673 1.12 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr20_-_43281269 1.11

chr23_-_27707182 1.10 ENSDART00000103639
arf3a
ADP-ribosylation factor 3a
chr2_-_49149839 1.10

chr18_+_39345919 1.09 ENSDART00000012164
tmod2
tropomodulin 2
chr24_+_41009372 1.08 ENSDART00000165952
CU633479.3
ENSDARG00000099523
chr16_-_31517858 1.06 ENSDART00000145691
ENSDARG00000054814
ENSDARG00000054814
chr6_-_52234640 1.05 ENSDART00000133554
tomm34
translocase of outer mitochondrial membrane 34
chr11_+_25266623 1.04 ENSDART00000154213
tfe3b
transcription factor binding to IGHM enhancer 3b
chr25_+_20618512 1.04 ENSDART00000144748
ergic2
ERGIC and golgi 2
chr18_+_40365208 1.02 ENSDART00000167134
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr25_+_3551924 1.02 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr3_+_34063993 1.02

chr3_+_22724101 1.01 ENSDART00000167127
BX322574.1
ENSDARG00000098353
chr6_+_19476528 1.01 ENSDART00000113911
micall1a
MICAL-like 1a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.5 GO:0051899 regulation of mitochondrial membrane potential(GO:0051881) membrane depolarization(GO:0051899) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
1.4 20.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.3 3.8 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
1.2 3.7 GO:0097377 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
1.2 7.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
1.1 11.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
1.0 5.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.9 7.1 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.9 4.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.8 1.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.6 1.9 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.6 1.8 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.5 2.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.5 9.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.5 2.0 GO:0031033 myosin filament organization(GO:0031033)
0.4 4.9 GO:0007525 somatic muscle development(GO:0007525)
0.4 2.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.4 2.9 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.4 2.1 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.4 1.2 GO:0019323 pentose catabolic process(GO:0019323)
0.4 4.5 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.4 4.8 GO:0061337 cardiac conduction(GO:0061337)
0.3 2.4 GO:0090303 positive regulation of wound healing(GO:0090303)
0.3 5.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 5.8 GO:0071711 basement membrane organization(GO:0071711)
0.3 2.4 GO:0070650 actin filament bundle distribution(GO:0070650)
0.3 3.5 GO:0046686 response to cadmium ion(GO:0046686)
0.3 2.7 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 3.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.3 0.9 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.3 4.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.3 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3 2.4 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.3 3.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.2 3.7 GO:0007634 optokinetic behavior(GO:0007634)
0.2 5.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 1.1 GO:0015744 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.2 5.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.2 1.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 0.6 GO:0045905 positive regulation of translational termination(GO:0045905)
0.2 0.6 GO:0055004 atrial cardiac myofibril assembly(GO:0055004)
0.2 1.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.0 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.2 2.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 1.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 5.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 3.4 GO:0021986 habenula development(GO:0021986)
0.1 1.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 1.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.5 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 2.5 GO:0051014 actin filament severing(GO:0051014)
0.1 1.0 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.1 1.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 3.2 GO:0007416 synapse assembly(GO:0007416)
0.1 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 3.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 2.4 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 3.4 GO:0007601 visual perception(GO:0007601)
0.0 0.9 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 4.3 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 6.5 GO:0001756 somitogenesis(GO:0001756)
0.0 3.2 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 2.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 3.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 3.3 GO:0060047 heart contraction(GO:0060047)
0.0 3.1 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.3 GO:0001817 regulation of cytokine production(GO:0001817)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.9 GO:0015711 organic anion transport(GO:0015711)
0.0 1.4 GO:0021782 glial cell development(GO:0021782)
0.0 1.3 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.6 GO:1901532 regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 3.2 GO:0006955 immune response(GO:0006955)
0.0 0.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 3.7 GO:0006811 ion transport(GO:0006811)
0.0 2.7 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.5 GO:0006414 translational elongation(GO:0006414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 8.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.0 11.1 GO:0031430 M band(GO:0031430)
0.9 4.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.7 9.6 GO:0005869 dynactin complex(GO:0005869)
0.7 5.3 GO:0031672 A band(GO:0031672)
0.6 4.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.6 3.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.5 5.2 GO:0030056 hemidesmosome(GO:0030056)
0.5 2.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.4 3.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.4 4.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 12.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 5.3 GO:0005861 troponin complex(GO:0005861)
0.2 6.8 GO:0016342 catenin complex(GO:0016342)
0.2 1.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 2.4 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.7 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 3.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.1 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 3.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 2.4 GO:0030175 filopodium(GO:0030175)
0.1 2.7 GO:0016605 PML body(GO:0016605)
0.1 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.9 GO:0016459 myosin complex(GO:0016459)
0.1 3.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.8 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 18.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.7 GO:0030425 dendrite(GO:0030425)
0.0 21.2 GO:0005576 extracellular region(GO:0005576)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.9 GO:0005840 ribosome(GO:0005840)
0.0 0.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 3.2 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 6.1 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 3.2 GO:0045202 synapse(GO:0045202)
0.0 0.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.9 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.6 GO:0016936 galactoside binding(GO:0016936)
1.4 7.1 GO:0034632 retinol transporter activity(GO:0034632)
1.0 5.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.0 9.1 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.9 2.7 GO:0005521 lamin binding(GO:0005521)
0.5 7.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.5 5.2 GO:0030506 ankyrin binding(GO:0030506)
0.5 4.5 GO:0051117 ATPase binding(GO:0051117)
0.4 7.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 8.7 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.4 1.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 5.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 3.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 3.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 2.2 GO:0005522 profilin binding(GO:0005522)
0.3 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 6.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 3.6 GO:0002039 p53 binding(GO:0002039)
0.2 1.1 GO:0015141 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.2 3.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 4.4 GO:0044325 ion channel binding(GO:0044325)
0.2 5.0 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.1 6.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 2.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.1 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 72.3 GO:0005509 calcium ion binding(GO:0005509)
0.1 1.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 2.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 4.8 GO:0046332 SMAD binding(GO:0046332)
0.1 3.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.9 GO:0016208 AMP binding(GO:0016208)
0.1 3.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.0 GO:0031072 heat shock protein binding(GO:0031072)
0.1 5.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 2.4 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.7 GO:0005254 chloride channel activity(GO:0005254)
0.0 2.9 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 3.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 2.3 GO:0019838 growth factor binding(GO:0019838)
0.0 12.6 GO:0003779 actin binding(GO:0003779)
0.0 1.1 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.7 GO:0060090 binding, bridging(GO:0060090)
0.0 1.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 5.5 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.5 GO:0008134 transcription factor binding(GO:0008134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.5 4.0 PID IL5 PATHWAY IL5-mediated signaling events
0.2 4.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.8 PID INSULIN PATHWAY Insulin Pathway
0.1 5.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.6 9.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.5 3.2 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.4 0.9 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.4 3.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.4 2.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 5.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 2.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.3 6.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 1.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 3.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production