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Results for meox2b

Z-value: 0.71

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Transcription factors associated with meox2b

Gene Symbol Gene ID Gene Info
ENSDARG00000061818 mesenchyme homeobox 2b

Activity profile of meox2b motif

Sorted Z-values of meox2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of meox2b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_56157608 2.03 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_+_68410884 1.54 ENSDART00000153691
ENSDARG00000097815
chr10_+_39141022 1.51 ENSDART00000158245
si:ch73-1a9.3
chr14_+_46419051 1.33 ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr3_+_56970554 1.30 ENSDART00000162930
BAH domain and coiled-coil containing 1a
chr7_-_25623974 1.22 ENSDART00000173602
CD99 molecule-like 2
chr11_-_29910947 1.20 ENSDART00000156121
sex comb on midleg-like 2 (Drosophila)
chr16_+_29060022 1.16 ENSDART00000088023
gon-4-like (C. elegans)
chr16_+_23516127 1.16 ENSDART00000004679
ictacalcin
chr25_+_14411153 1.15 ENSDART00000015681
developing brain homeobox 1b
chr20_-_9107294 1.15 ENSDART00000140792
OMA1 zinc metallopeptidase
chr23_-_12310778 1.13 ENSDART00000131256
phosphatase and actin regulator 3a
chr19_-_43037791 1.12 ENSDART00000004392
FK506 binding protein 9
chr2_+_33343287 1.12 ENSDART00000056655
Kruppel-like factor 17
chr2_+_32036450 1.10 ENSDART00000140776
ENSDARG00000091946
chr7_-_52848084 1.05 ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr16_+_13928844 1.01 ENSDART00000090191
folliculin
chr11_+_34788205 1.01 ENSDART00000124800
family with sequence similarity 212, member Aa
chr24_-_21778717 0.99 ENSDART00000131944
transgelin 3b
chr25_+_31457309 0.98 ENSDART00000022325
poly (ADP-ribose) polymerase family, member 16
chr22_-_15567180 0.96 ENSDART00000123125
tropomyosin 4a
chr4_-_2615160 0.94 ENSDART00000140760
E2F transcription factor 7
chr24_+_5205878 0.91 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr11_-_2107054 0.89 ENSDART00000173031
homeobox C6b
chr24_+_17125429 0.87 ENSDART00000017605
sperm associated antigen 6
chr6_+_3873114 0.87 ENSDART00000159952
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr3_+_17387551 0.86 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr23_+_19887319 0.86 ENSDART00000139192
emerin (Emery-Dreifuss muscular dystrophy)
chr9_+_25966093 0.86 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr13_+_35213326 0.85 ENSDART00000019323
jagged 1b
chr21_-_22510751 0.84 ENSDART00000169870
myosin VB
chr24_-_6048914 0.84 ENSDART00000146830
ENSDART00000021981
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_-_7576069 0.83 ENSDART00000148836
regulatory factor X, 5
chr1_-_57300743 0.83 ENSDART00000081122
collagen beta(1-O)galactosyltransferase 1
chr4_+_3970874 0.83 ENSDART00000049194
G protein-coupled receptor 37b
chr19_+_7234029 0.82 ENSDART00000080348
bromodomain containing 2a
chr25_-_30845998 0.81 ENSDART00000027661
myogenic differentiation 1
chr1_-_40536800 0.81 ENSDART00000134739
regulator of G protein signaling 12b
chr13_+_27102377 0.80 ENSDART00000138043
Ras and Rab interactor 2
chr8_+_2428689 0.80 ENSDART00000081325
dynein, light chain, LC8-type 1
chr13_+_27102308 0.80 ENSDART00000145901
Ras and Rab interactor 2
chr6_-_23193752 0.79 ENSDART00000159749
ubiquitin specific peptidase 43a
chr8_+_21321765 0.79 ENSDART00000131691
aminolevulinate, delta-, synthase 2
chr2_+_25468904 0.78 ENSDART00000056801
male-specific lethal 2 homolog a (Drosophila)
chr1_+_32935645 0.77 ENSDART00000170832
ADP-ribosylation factor-like 13b
chr6_+_47425082 0.77 ENSDART00000171087
si:ch211-286o17.1
chr4_-_22751641 0.77 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
lysine (K)-specific methyltransferase 2E
chr24_-_39722595 0.76 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr9_-_41608298 0.76

chr18_-_782643 0.76 ENSDART00000161084
si:dkey-205h23.1
chr10_+_39140943 0.76 ENSDART00000158245
si:ch73-1a9.3
chr2_+_49358871 0.75 ENSDART00000179089
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr6_+_16341787 0.75 ENSDART00000114667
zgc:161969
chr22_-_22846670 0.75 ENSDART00000176355
ENSDARG00000108442
chr4_-_59767735 0.75 ENSDART00000159114
zinc finger protein 1129
chr9_-_48098629 0.75

chr21_+_26684617 0.75 ENSDART00000053797
solute carrier family 3 (amino acid transporter heavy chain), member 2b
chr1_+_13779755 0.74

chr5_-_40707316 0.74 ENSDART00000161932
natriuretic peptide receptor 3
chr23_-_23474703 0.74 ENSDART00000078936
hairy-related 9
chr16_-_17439735 0.73 ENSDART00000144392
zyxin
chr21_-_8420626 0.73 ENSDART00000084378
crumbs family member 2a
chr22_-_26333957 0.73 ENSDART00000130493
calpain 2, (m/II) large subunit b
chr17_-_14868764 0.73 ENSDART00000115064
nidogen 2a (osteonidogen)
chr2_-_34010299 0.73 ENSDART00000140910
patched 2
chr14_+_20045365 0.72 ENSDART00000167637
AF4/FMR2 family, member 2
chr11_-_44724371 0.72 ENSDART00000166501
calcium activated nucleotidase 1b
chr8_-_22945616 0.71

chr7_-_33921565 0.71 ENSDART00000125131
SMAD family member 6a
chr12_-_5693715 0.71 ENSDART00000105887
distal-less homeobox 4b
chr19_+_22478256 0.71 ENSDART00000100181
spalt-like transcription factor 3b
chr16_+_46145286 0.70 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr16_+_11138924 0.70 ENSDART00000091183
Ets2 repressor factor like 3
chr20_-_35343057 0.70 ENSDART00000113294
frizzled class receptor 3a
chr10_-_15896595 0.70 ENSDART00000092343
tight junction protein 2a (zona occludens 2)
chr21_-_25567978 0.69 ENSDART00000133134
EGF containing fibulin-like extracellular matrix protein 2b
chr13_+_27654900 0.68 ENSDART00000160550
ENSDARG00000102040
chr9_-_18903879 0.68 ENSDART00000138785
si:dkey-239h2.3
chr23_+_6043862 0.68

chr11_+_37639045 0.68 ENSDART00000111157
si:ch211-112f3.4
chr11_+_14142126 0.68 ENSDART00000102520
paralemmin 1a
chr13_+_2774422 0.67 ENSDART00000162362
wu:fj16a03
chr8_-_17480730 0.67 ENSDART00000100667
v-ski avian sarcoma viral oncogene homolog a
chr1_-_23765358 0.67

chr7_+_34018862 0.67 ENSDART00000123498
fin bud initiation factor b
chr3_-_23513177 0.67 ENSDART00000078425
even-skipped-like1
chr24_+_38371710 0.66 ENSDART00000105672
myosin binding protein C, fast type b
chr16_+_24046472 0.66

chr20_-_36984259 0.66 ENSDART00000076313
taxilin beta a
chr10_-_17630376 0.66 ENSDART00000113101
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 b
chr24_+_16998329 0.65 ENSDART00000177272
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr7_-_32888309 0.65 ENSDART00000173461
ENSDARG00000105655
chr4_-_73485204 0.65 ENSDART00000122898
PHD finger protein 21B
chr20_-_21031504 0.64 ENSDART00000152726
BTB (POZ) domain containing 6b
chr15_-_18159904 0.64 ENSDART00000170874
pleckstrin homology-like domain, family B, member 1b
chr2_+_27344633 0.64 ENSDART00000178275
cadherin 7, type 2
chr3_+_18249107 0.63 ENSDART00000141100
ENSDART00000138107
ribosomal protein S2
chr15_+_29343644 0.63 ENSDART00000170537
ENSDART00000128973
RAP1 GTPase activating protein 2a
chr12_+_3043444 0.63 ENSDART00000149427
sarcoglycan, alpha
chr12_+_20230575 0.63 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr12_-_4497094 0.63 ENSDART00000163651
transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
chr16_-_7525980 0.63 ENSDART00000017445
PR domain containing 1a, with ZNF domain
chr10_+_42530040 0.62 ENSDART00000025691
drebrin-like a
chr20_-_3970778 0.62 ENSDART00000178724
ENSDART00000178565
tripartite motif containing 67
chr15_-_28663537 0.62 ENSDART00000156800
si:ch211-225b7.5
chr5_+_26925238 0.61 ENSDART00000051491
secreted frizzled-related protein 1a
chr16_+_11138879 0.61 ENSDART00000091183
Ets2 repressor factor like 3
chr17_+_23278879 0.61 ENSDART00000153652
zgc:165461
chr8_+_49789789 0.61 ENSDART00000083790
neurotrophic tyrosine kinase, receptor, type 2a
chr9_-_20562293 0.61 ENSDART00000113418
immunoglobulin superfamily, member 3
chr15_-_1858350 0.61 ENSDART00000082026
matrix metallopeptidase 28
chr17_+_15425559 0.60 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr19_+_12995955 0.60 ENSDART00000132892
collagen triple helix repeat containing 1a
chr16_-_45269179 0.60 ENSDART00000162095
si:dkey-33i11.4
chr19_-_31815128 0.60 ENSDART00000137292
transmembrane protein 106Bb
chr2_-_23348612 0.59 ENSDART00000110373
zinc finger protein 414
chr18_+_5899355 0.59

chr2_+_57903155 0.59

chr25_+_30699938 0.59 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr7_-_72278552 0.59 ENSDART00000168532
HECT domain E3 ubiquitin protein ligase 4
chr21_+_17731439 0.59 ENSDART00000124173
retinoid X receptor, alpha a
chr18_-_3056732 0.59 ENSDART00000162657
ribosomal protein S3
chr4_-_15442828 0.59 ENSDART00000157414
plexin A4
chr4_+_18974767 0.59 ENSDART00000066973
IMP (inosine 5'-monophosphate) dehydrogenase 1b
chr8_+_30443651 0.58 ENSDART00000062303
forkhead box D5
chr4_-_51772774 0.58

chr23_-_22186674 0.57 ENSDART00000142474
polyhomeotic homolog 2a (Drosophila)
chr17_+_24668907 0.57 ENSDART00000034263
ENSDART00000135794
selenoprotein N, 1
chr15_-_14616083 0.57 ENSDART00000171169
numb homolog (Drosophila)-like
chr17_-_29102320 0.57 ENSDART00000104204
forkhead box G1a
chr22_-_15930756 0.56 ENSDART00000080047
epidermal growth factor receptor pathway substrate 15-like 1a
chr2_+_44692913 0.56 ENSDART00000155362
ENSDARG00000079124
chr6_-_54816183 0.56 ENSDART00000148462
troponin I type 1b (skeletal, slow)
chr22_-_24341408 0.56

chr13_-_31165867 0.56 ENSDART00000030946
PR domain containing 8
chr6_-_40314512 0.55 ENSDART00000033844
collagen, type VII, alpha 1
chr16_-_28943421 0.55 ENSDART00000149501
si:dkey-239n17.4
chr5_-_64149931 0.54 ENSDART00000144816
limb and CNS expressed 1
chr8_+_2260519 0.54 ENSDART00000136743
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr8_-_17580655 0.54

chr3_-_59884282 0.54 ENSDART00000156597
si:ch73-364h19.1
chr6_-_55881470 0.54 ENSDART00000160991
cytochrome P450, family 24, subfamily A, polypeptide 1
chr8_-_23591082 0.54 ENSDART00000025024
solute carrier family 38, member 5b
chr22_+_9889203 0.53 ENSDART00000177953
bloody fingers
chr3_+_28822408 0.53 ENSDART00000133528
lectin, galactoside-binding, soluble, 2a
chr11_-_17620732 0.52 ENSDART00000154627
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr3_-_60929921 0.52 ENSDART00000055064
parvalbumin 8
chr18_+_618393 0.52 ENSDART00000159464
neural precursor cell expressed, developmentally down-regulated 4a
chr22_+_2921305 0.52 ENSDART00000143258
centrosomal protein 19
chr14_-_4166292 0.52 ENSDART00000127318
FERM and PDZ domain containing 1b
chr11_+_29753417 0.52

chr1_+_16681778 0.52

chr6_+_54231519 0.52 ENSDART00000149542
protein kinase C and casein kinase substrate in neurons 1b
chr20_-_29517770 0.51 ENSDART00000147464
ryanodine receptor 3
chr3_-_60866373 0.51 ENSDART00000112043
calcium channel, voltage-dependent, gamma subunit 4b
chr15_+_42329269 0.51 ENSDART00000099234
ENSDART00000152731
SR-related CTD-associated factor 4b
chr7_+_30516734 0.51 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr8_+_46378250 0.51 ENSDART00000129661
ENSDART00000084081
8-oxoguanine DNA glycosylase
chr15_-_734338 0.51 ENSDART00000155878
si:dkey-7i4.23
chr23_+_11350727 0.51

chr22_-_36561247 0.50 ENSDART00000056188
info polymerase (RNA) II (DNA directed) polypeptide H
chr14_-_45883839 0.50

chr9_-_35205969 0.50

chr6_+_50393779 0.50 ENSDART00000055502
ERGIC and golgi 3
chr6_-_43273456 0.49

chr22_-_864745 0.49 ENSDART00000035514
choline/ethanolamine phosphotransferase 1b
chr24_+_7832020 0.49 ENSDART00000019705
bone morphogenetic protein 6
chr2_+_26632673 0.49 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr24_+_35500964 0.49 ENSDART00000058571
snail family zinc finger 2
chr15_+_880573 0.49 ENSDART00000115077
zgc:174573
chr15_-_40391882 0.49

chr2_-_32370176 0.49 ENSDART00000077151
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr25_-_5835981 0.48 ENSDART00000155751
NUAK family, SNF1-like kinase, 1b
chr4_+_14728248 0.48 ENSDART00000124189
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr4_+_9668755 0.48 ENSDART00000004604
si:dkey-153k10.9
chr19_+_19939410 0.48

chr20_+_55096127 0.48

chr13_+_33151628 0.48 ENSDART00000135200
coiled-coil domain containing 28B
chr2_-_23516930 0.48 ENSDART00000165355
paired related homeobox 1a
chr17_-_25630666 0.48 ENSDART00000149060
protein phosphatase 1, catalytic subunit, beta isozyme
chr7_+_54410044 0.47

chr21_+_28408329 0.47 ENSDART00000077871
phosphorylase, glycogen, muscle A
chr21_+_25199691 0.47 ENSDART00000168140
ENSDART00000112783
transmembrane protein 45B
chr9_-_56292487 0.47 ENSDART00000151720
si:ch211-39i22.1
chr22_+_16509286 0.47 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr11_-_6442836 0.47 ENSDART00000004483
zgc:162969
chr1_-_40587797 0.47 ENSDART00000170895
regulator of G protein signaling 12b
chr9_+_25966225 0.47 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr16_+_43249142 0.47 ENSDART00000154493
ADAM metallopeptidase domain 22
chr22_+_223797 0.47

chr12_+_24221087 0.47 ENSDART00000088178
neurexin 1a
chr21_+_10663517 0.46 ENSDART00000074833
retinal homeobox gene 3
chr7_-_72500748 0.46 ENSDART00000160523
ENSDARG00000099109
chr22_-_36783601 0.46

chr24_-_14447773 0.46

chr12_+_1572834 0.45

chr2_-_10919978 0.45 ENSDART00000005944
ribosomal protein L5a
chr9_-_12453581 0.45 ENSDART00000088199
zgc:162707
chr21_-_17259886 0.45 ENSDART00000114877
growth factor independent 1B transcription repressor
chr3_-_21217799 0.45 ENSDART00000114906
family with sequence similarity 171, member A2a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.3 0.9 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.3 0.9 GO:0001659 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.3 0.8 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.3 1.1 GO:0048785 hatching gland development(GO:0048785)
0.3 1.0 GO:0086014 atrial cardiac muscle cell action potential(GO:0086014) cell-cell signaling involved in cardiac conduction(GO:0086019) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) cell communication involved in cardiac conduction(GO:0086065) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
0.3 0.8 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 1.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.2 1.0 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379)
0.2 0.6 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.2 0.6 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.2 0.6 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2 0.6 GO:1902024 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.2 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.7 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.5 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.2 0.8 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.2 0.8 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 0.5 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521) microglia development(GO:0014005) regulation of cellular amine metabolic process(GO:0033238)
0.1 0.7 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 2.4 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.7 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0033280 response to vitamin D(GO:0033280) vitamin D metabolic process(GO:0042359)
0.1 0.5 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.4 GO:0052803 imidazole-containing compound metabolic process(GO:0052803) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.9 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 0.3 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.7 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.4 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.4 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 0.3 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.9 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 0.4 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 2.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.8 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.6 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.0 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.5 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 0.4 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1 0.7 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.4 GO:0045056 transcytosis(GO:0045056)
0.1 0.2 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.1 0.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.7 GO:0046037 GMP biosynthetic process(GO:0006177) GTP biosynthetic process(GO:0006183) GMP metabolic process(GO:0046037)
0.1 0.4 GO:0035637 multicellular organismal signaling(GO:0035637)
0.1 0.6 GO:0043584 nose development(GO:0043584)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.2 GO:0051414 response to cortisol(GO:0051414) cellular response to cortisol stimulus(GO:0071387)
0.1 0.2 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.6 GO:0015671 oxygen transport(GO:0015671)
0.1 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.3 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.6 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.7 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.1 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.1 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.9 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 2.1 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.2 GO:1990481 snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.1 0.3 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.3 GO:0036268 swimming(GO:0036268)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.5 GO:0003313 heart rudiment development(GO:0003313)
0.0 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.7 GO:0055017 cardiac muscle tissue growth(GO:0055017)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.5 GO:0044247 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.4 GO:0030241 skeletal muscle thin filament assembly(GO:0030240) skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0003232 bulbus arteriosus development(GO:0003232)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.8 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.7 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.6 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.9 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 1.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.2 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.0 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.0 0.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0006956 complement activation(GO:0006956)
0.0 0.2 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 1.1 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.5 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.6 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.6 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.5 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.8 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.3 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.1 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.4 GO:0015696 ammonium transport(GO:0015696)
0.0 0.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.0 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.3 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.0 GO:0001708 cell fate specification(GO:0001708)
0.0 0.1 GO:0001881 receptor recycling(GO:0001881)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603) positive regulation of organelle assembly(GO:1902117)
0.0 0.3 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0060173 limb development(GO:0060173)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0032475 otolith formation(GO:0032475)
0.0 0.2 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0097189 apoptotic body(GO:0097189)
0.1 0.6 GO:0031838 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.1 0.6 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.0 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.8 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.0 GO:0005604 basement membrane(GO:0005604) extracellular matrix component(GO:0044420)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0030677 nucleoid(GO:0009295) ribonuclease P complex(GO:0030677) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0031674 I band(GO:0031674)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.4 GO:0008305 integrin complex(GO:0008305)
0.0 0.3 GO:0030118 clathrin coat(GO:0030118)
0.0 0.0 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0044304 main axon(GO:0044304)
0.0 0.4 GO:0014069 postsynaptic density(GO:0014069)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 0.7 GO:0008158 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.1 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0016841 folic acid binding(GO:0005542) ammonia-lyase activity(GO:0016841)
0.1 0.7 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.5 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.4 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.3 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.6 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.2 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.2 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0019869 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0035381 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.7 GO:0016247 channel regulator activity(GO:0016247)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 5.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0015141 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.9 GO:0046332 SMAD binding(GO:0046332)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.0 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.1 GO:0004691 AMP-activated protein kinase activity(GO:0004679) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.5 GO:0019955 cytokine binding(GO:0019955)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008009 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0005158 insulin receptor binding(GO:0005158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 2.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.6 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 2.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors