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Results for mespab+mespba_id4
Z-value: 3.60
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Transcription factors associated with mespab+mespba_id4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| id4 | dr10_dc_chr16_-_10089440_10089472 | -0.81 | 1.3e-04 | Click! |
| mespba | dr10_dc_chr7_+_15059782_15059806 | 0.78 | 3.9e-04 | Click! |
| mespab | dr10_dc_chr25_-_10919875_10919883 | -0.59 | 1.5e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of mespab+mespba_id4
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_58448953 Show fit | 25.24 |
ENSDART00000024185
|
zgc:56231 |
|
| chr21_-_30256477 Show fit | 17.18 |
ENSDART00000137193
|
stem-loop binding protein 2 |
|
| chr21_-_34227158 Show fit | 14.67 |
ENSDART00000169218
ENSDART00000064320 ENSDART00000172381 |
ALG13, UDP-N-acetylglucosaminyltransferase subunit |
|
| chr11_+_30005768 Show fit | 14.59 |
ENSDART00000167618
|
ENSDARG00000100936 |
|
| chr2_+_28199458 Show fit | 14.47 |
ENSDART00000150330
|
bucky ball |
|
| chr4_-_20456825 Show fit | 13.55 |
ENSDART00000003621
ENSDART00000132356 |
siaz-interacting nuclear protein |
|
| chr7_+_58449163 Show fit | 13.28 |
ENSDART00000167166
|
zgc:56231 |
|
| chr12_+_13053552 Show fit | 13.15 |
ENSDART00000124799
|
si:ch211-103b1.2 |
|
| chr13_-_21541531 Show fit | 13.00 |
ENSDART00000067537
|
ELOVL family member 6, elongation of long chain fatty acids like |
|
| chr23_+_540624 Show fit | 12.29 |
ENSDART00000034707
|
LSM family member 14B |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 70.8 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 1.4 | 30.1 | GO:0001840 | neural plate development(GO:0001840) |
| 1.6 | 27.4 | GO:2000344 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 2.6 | 26.2 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111) |
| 3.5 | 20.9 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.6 | 20.9 | GO:0048599 | oocyte development(GO:0048599) |
| 1.4 | 18.0 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.5 | 17.1 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 15.2 | GO:0015031 | protein transport(GO:0015031) |
| 4.8 | 14.5 | GO:0060832 | oocyte animal/vegetal axis specification(GO:0060832) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 67.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 2.9 | 26.2 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.2 | 19.9 | GO:0048475 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 1.5 | 19.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 15.6 | GO:0005938 | cell cortex(GO:0005938) |
| 0.3 | 15.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 4.8 | 14.5 | GO:0032019 | mitochondrial cloud(GO:0032019) |
| 0.7 | 12.7 | GO:0042555 | MCM complex(GO:0042555) |
| 3.9 | 11.7 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.1 | 11.7 | GO:0005770 | late endosome(GO:0005770) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 67.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 1.7 | 26.2 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 18.9 | GO:0005525 | GTP binding(GO:0005525) |
| 0.1 | 17.8 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
| 0.7 | 17.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.4 | 17.1 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 16.4 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.6 | 16.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 1.7 | 15.1 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.0 | 14.2 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 16.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.8 | 12.5 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.5 | 11.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.6 | 8.4 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.2 | 8.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.5 | 8.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.3 | 7.0 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.3 | 4.9 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 4.3 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 4.2 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 18.2 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 1.8 | 12.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.7 | 12.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.5 | 11.9 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 2.9 | 8.7 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 8.5 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 1.2 | 8.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 6.3 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.3 | 6.0 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 5.3 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |